Relationship between incomplete synapsis and chiasma localization.

abstract：:Mechanisms of chromosome condensation and segregation during the first meiotic division are not well understood. Resolution of recombination events to form chiasmata is important, for it is chiasmata that hold homologous chromosomes together for their oppositional orientation on the meiotic metaphase spindle, thus ens...

journal_title：Chromosoma

authors： Cobb J,Miyaike M,Kikuchi A,Handel MA

更新日期：1999-12-01 00:00:00

abstract：:Homologous chromosomes exchange genetic information through recombination during meiosis, a process that increases genetic diversity, and is fundamental to sexual reproduction. In an attempt to shed light on the dynamics of mammalian recombination and its implications for genome organization, we have studied the recom...

journal_title：Chromosoma

authors： Ruiz-Herrera A,Vozdova M,Fernández J,Sebestova H,Capilla L,Frohlich J,Vara C,Hernández-Marsal A,Sipek J,Robinson TJ,Rubes J

更新日期：2017-10-01 00:00:00

abstract：:To structurally dissect mitotic chromosomes, we aim to position along the folded chromatin fiber proteins involved in long-range order, such as topoisomerase IIalpha (topoIIalpha) and condensin. Immuno-electron microscopy (EM) of thin-sectioned chromosomes is the method of choice toward this goal. A much-improved immu...

journal_title：Chromosoma

authors： Maeshima K,Eltsov M,Laemmli UK

更新日期：2005-11-01 00:00:00

abstract：:A plant carrying a small extra chromosome was found in Landsberg erecta ecotype of Arabidopsis thaliana. Fluorescence in situ hybridization revealed that this minichromosome was derived from the short arm of chromosome 4. The size of this "mini4S" chromosome was estimated to be approximately 7.5 Mb on the basis of pre...

journal_title：Chromosoma

authors： Murata M,Shibata F,Yokota E

更新日期：2006-08-01 00:00:00

abstract：:Previous studies of the Robertsonian polymorphism in the Atlantic dog-whelk, Nucella lapillus (2n = 26-36), have been limited by the inability to identify unequivocally individual chromosomes in the karyotype. This species, as with many other marine invertebrates, has proven largely refractory to the standard (mammali...

journal_title：Chromosoma

authors： Pascoe PL,Patton SJ,Critcher R,Dixon DR

更新日期：1996-03-01 00:00:00

abstract：:X chromosome inactivation (XCI) is an essential mechanism to compensate gene dosage in mammals. Here, we show that XCI has evolved differently in two species of the genus Tokudaia. The Amami spiny rat, Tokudaia osimensis, has a single X chromosome in males and females (XO/XO). By contrast, the Okinawa spiny rat, Tokud...

journal_title：Chromosoma

authors： Zushi H,Murata C,Mizushima S,Nishida C,Kuroiwa A

更新日期：2017-12-01 00:00:00

abstract：:The sub-division of S-phase in Syrian hamsters, on the basis of Brd/U/Hoechst 33258/Giemsa banding, has allowed a quantitative comparison of the replication of individual chromosome bands within defined subphases of S. This analysis has shown that in hamsters, as has been reported in humans, there are distinct pattern...

journal_title：Chromosoma

authors： Cawood AH

更新日期：1981-01-01 00:00:00

abstract：:In this work we have used the inhibitor of F-actin polymerisation cytochalasin B (Cyt B) to test the hypothesis that the contractile ring and the central spindle are mutually interdependent structures in mammalian mitotic cells. Double fluorescence staining of alpha-tubulin and F-actin was employed to analyse anaphase...

journal_title：Chromosoma

authors： Cimini D,Fioravanti D,Tanzarella C,Degrassi F

更新日期：1998-12-01 00:00:00

abstract：:A crucial step during eukaryotic initiation of DNA replication is the correct loading and activation of the replicative DNA helicase, which ensures that each replication origin fires only once. Unregulated DNA helicase loading and activation, as it occurs in cancer, can cause severe DNA damage and genomic instability....

journal_title：Chromosoma

authors： Tognetti S,Riera A,Speck C

更新日期：2015-03-01 00:00:00

abstract：:By means of a cytological technique involving 5-bromodeoxyuridine, acridine orange, and fluorescence microscopy, the asynchronously replicating, hence genetically inactivated, X chromosome was identified in 6- to 8-day embryos from female mice heterozygous for Searle's translocation T(X;16)16H (abbreviated as T16H) ma...

journal_title：Chromosoma

authors： Takagi N

更新日期：1980-01-01 00:00:00

abstract：:The divergence of lineages leading to extant squamate reptiles (lizards, snakes, and amphisbaenians) and birds occurred about 275 million years ago. Birds, unlike squamates, have karyotypes that are typified by the presence of a number of very small chromosomes. Hence, a number of chromosome rearrangements might be ex...

journal_title：Chromosoma

authors： Pokorná M,Giovannotti M,Kratochvíl L,Kasai F,Trifonov VA,O'Brien PC,Caputo V,Olmo E,Ferguson-Smith MA,Rens W

更新日期：2011-10-01 00:00:00

abstract：:Dioecious species accounted for 6% of all plant species, including a number of crops and economically important species, such as poplar. However, sex determination and sex chromosome evolution have been studied only in few dioecious species. In poplar, the sex-determining locus was mapped to chromosome 19. Interesting...

journal_title：Chromosoma

authors： Xin H,Zhang T,Han Y,Wu Y,Shi J,Xi M,Jiang J

更新日期：2018-09-01 00:00:00

abstract：:The nature of replication origins in eukaryotic chromosomes has been examined in some detail only in yeast, Drosophila, and mammalian cells. We have used highly synchronous cultures of plasmodia of the myxomycete Physarum and two-dimensional agarose gel electrophoresis to examine replication of two developmentally con...

journal_title：Chromosoma

authors： Diller JD,Sauer HW

更新日期：1993-09-01 00:00:00

abstract：:The distinctive behaviors of chromosomes in mitosis and meiosis depend upon differences in kinetochore position. Kinetochore position is well established except for a critical transition between meiosis I and meiosis II. We examined kinetochore position during the transition and compared it with the position of kineto...

journal_title：Chromosoma

authors： Paliulis LV,Nicklas RB

更新日期：2005-03-01 00:00:00

abstract：:Studies using human and mouse cells have revealed some changes to non-telomeric chromatin and gene expression in response to abnormally short telomeres. To investigate this further, we studied the effect of inheriting shorter telomeres on transcription and genetic stability at non-telomeric sites in the mouse. Using m...

journal_title：Chromosoma

authors： Roberts AR,Huang E,Jones L,Daxinger L,Chong S,Whitelaw E

更新日期：2013-12-01 00:00:00

abstract：:The distribution of intermicrotubular bridges in spindles of tipulid spermatocytes (Pales ferruginea, first meiotic division) was analyzed using serial sections of pre-selected cells. Bridges were found in all spindle regions, including kinetochore microtubules and free microtubules in the chromosome fiber. The dimens...

journal_title：Chromosoma

authors： Bastmeyer M,Fuge H

更新日期：1986-01-01 00:00:00

abstract：:In a variety of organisms, euchromatic genes brought into juxtaposition with pericentric heterochromatin show position-effect variegation (PEV), a silencing of gene expression in a subset of the cells in which the gene is normally expressed. Previously, a P-element mobilization screen identified transgenic Drosophila ...

journal_title：Chromosoma

authors： Cryderman DE,Cuaycong MH,Elgin SC,Wallrath LL

更新日期：1998-11-01 00:00:00

abstract：:The chromosomes of lake trout (Salvelinus namaycush) contain a considerable amount of heterochromatin located at the centromeres and/or telomeres of several chromosomes, including a sex-specific block located distally on the X chromosome. In order to investigate further the repetitive DNAs of lake trout, genomic DNA f...

journal_title：Chromosoma

authors： Reed KM,Phillips RB

更新日期：1995-12-01 00:00:00

abstract：:We describe a mammalian artificial mini-chromosome lacking human alphoid DNA and mouse minor and major satellite DNA repeats. This mini-chromosome, initially recovered in a mouse embryonic stem (ES) cell line (CGR8), is 2.6 Mb in size and consists of sequences derived from the human Y chromosome and mouse chromosomes ...

journal_title：Chromosoma

authors： Shen MH,Ross A,Yang J,de las Heras JI,Cooke H

更新日期：2001-11-01 00:00:00

abstract：:The immunodeficiency, centromeric region instability, facial anomalies (ICF) syndrome is a rare autosomal recessive disease. Usually, it is caused by mutations in the DNA methyltransferase 3B gene, which result in decreased methylation of satellite DNA in the juxtacentromeric heterochromatin at 1qh, 16qh, and 9qh. Sat...

journal_title：Chromosoma

authors： Gisselsson D,Shao C,Tuck-Muller CM,Sogorovic S,Pålsson E,Smeets D,Ehrlich M

更新日期：2005-07-01 00:00:00

abstract：:We probed the complex between oriC and DnaA protein using two types of mutants in oriC. Base changes in the DnaA binding sites, DnaA boxes, had little effect on origin function. Mutations which change the distance between DnaA boxes R3 and R4, on the other hand, inactivated oriC unless the mutation deleted or inserted...

journal_title：Chromosoma

authors： Messer W,Hartmann-Kühlein H,Langer U,Mahlow E,Roth A,Schaper S,Urmoneit B,Woelker B

更新日期：1992-01-01 00:00:00

abstract：:In mammals, X-inactivation process is achieved by the cis-spreading of long noncoding Xist RNA over one of the female X chromosomes. The Xist binding accumulates histones H3 methylation and H4 hypoacetylation required for X inactivation that leads to proper dosage compensation of the X-linked genes. Co-transcription o...

journal_title：Chromosoma

authors： Kota SK,Roy Chowdhury D,Rao LK,Padmalatha V,Singh L,Bhadra U

更新日期：2015-06-01 00:00:00

abstract：:Allopolyploidy and homoeologous recombination are two important processes in reshaping genomes and generating evolutionary novelties. Newly formed allopolyploids usually display chromosomal perturbations as a result of pairing errors at meiosis. To understand mechanisms of stabilization of allopolyploid species derive...

journal_title：Chromosoma

authors： Wang Y,Zhao Q,Qin X,Yang S,Li Z,Li J,Lou Q,Chen J

更新日期：2017-12-01 00:00:00

abstract：:Insulator proteins orchestrate the three-dimensional organization of the genome. Insulators function by facilitating communications between regulatory sequences and gene promoters, allowing accurate gene transcription regulation during embryo development and cell differentiation. However, the role of insulator protein...

journal_title：Chromosoma

authors： Hsu SJ,Stow EC,Simmons JR,Wallace HA,Lopez AM,Stroud S,Labrador M

更新日期：2020-12-01 00:00:00

abstract：:The fourth chromosome smallest in the genome of Drosophila melanogaster differs from other chromosomes in many ways. It has high repeat density in conditions of a large number of active genes. Gray bands represent a significant part of this polytene chromosome. Specific proteins including HP1a, POF, and dSETDB1 establ...

journal_title：Chromosoma

authors： Sidorenko DS,Sidorenko IA,Zykova TY,Goncharov FP,Larsson J,Zhimulev IF

更新日期：2019-06-01 00:00:00

abstract：:Evidence is presented that chromosome ends are attached to the nuclear envelope prior to the formation of axial cores during early meiotic prophase in the grasshopper Brachystola magna. The attachment sites of distal and proximal chromosome ends are clustered in a small region of the inner nuclear envelope resulting i...

journal_title：Chromosoma

authors： Church K

更新日期：1976-11-29 00:00:00

abstract：:The Bacillus subtilis phage phi 29 DNA polymerase, involved in protein-primed viral DNA replication, contains several amino acid consensus sequences common to other eukaryotic-type DNA polymerases. Using site-directed mutagenesis, we have studied the functional significance of a C-terminal conserved region, represente...

journal_title：Chromosoma

authors： Blasco MA,Esteban JA,Méndez J,Blanco L,Salas M

更新日期：1992-01-01 00:00:00

abstract：:The zebra finch (Taeniopygia guttata) has a large Z chromosome and highly condensed W chromosome. We used the random amplified polymorphic DNA (RAPD) polymerase chain reaction (PCR) technique to isolate female-specific sequences ZBM1 and ZBM2. Southern blot hybridization to male and female zebra finch genomic DNA sugg...

journal_title：Chromosoma

authors： Itoh Y,Kampf K,Arnold AP

更新日期：2008-04-01 00:00:00

abstract：:Almost half of the human genome consists of repetitive DNA. Understanding what role these elements have in setting up chromatin states that underlie gene and chromosome function in complex genomes is paramount. The function of some types of repetitive DNA is obvious by virtue of their location, such as the alphoid arr...

journal_title：Chromosoma

authors： Chadwick BP

更新日期：2009-12-01 00:00:00

abstract：:An unstable minichromosome comprising part of the short arm of chromosome 10 of maize was recovered from an oil yellow variegated plant as a consequence of gamma irradiation of pollen. The cytological and gene dosage observations are consistent with the minichromosome being a partial isochromosome, which lags at mitot...

journal_title：Chromosoma

authors： Brock RD,Pryor AJ

更新日期：1996-06-01 00:00:00