当前位置： SCI文献检索 > JOURNAL OF AFFECTIVE DISORDERS期刊下所有文献 > Magnetization transfer imaging reveals the brain deficit in patients with treatment-refractory depression.

Magnetization transfer imaging reveals the brain deficit in patients with treatment-refractory depression.

Abstract：

BACKGROUND:Studies on treatment resistant depression (TRD) using advanced magnetic resonance imaging techniques are very limited. METHODS:A group of 15 patients with clinically defined TRD and 15 matched healthy controls underwent magnetization transfer imaging (MTI) and T1-weighted (T1W) imaging. MTI data were processed and analyzed voxel-wised in SPM2. A voxel based morphometric (VBM) analysis was performed using T1W images. RESULTS:Reduced magnetization transfer ratio was observed in the TRD group relative to normal controls in the anterior cingulate, insula, caudate tail and amygdala-parahippocampal areas. All these regions were identified within the right hemisphere. VBM revealed no morphological abnormalities in the TRD group compared to the control group. Negative correlations were found between MRI and clinical measures in the inferior temporal gyrus. LIMITATIONS:The cross-sectional design and small sample size. CONCLUSIONS:The findings suggest that MTI is capable of identifying subtle brain abnormalities which underlie TRD and in general more sensitive than morphological measures.

journal_name

J Affect Disord

journal_title

Journal of affective disorders

authors

Zhang TJ,Wu QZ,Huang XQ,Sun XL,Zou K,Lui S,Liu F,Hu JM,Kuang WH,Li DM,Li F,Chen HF,Chan RC,Mechelli A,Gong QY

doi

10.1016/j.jad.2009.01.003

subject

Has Abstract

pub_date

2009-10-01 00:00:00

pages

157-61

issue

3

eissn

0165-0327

issn

1573-2517

pii

S0165-0327(09)00005-6

journal_volume

117

pub_type

杂志文章

相关文献

JOURNAL OF AFFECTIVE DISORDERS文献大全
  • The categorisation of dysthymic disorder: can its constituents be meaningfully apportioned?

    abstract：BACKGROUND:Since its introduction in DSM-III, the validity of dysthymia has been debated. Our objective is to further examine the concept of dysthymia in an outpatient sample, and explore whether its constituents can be meaningfully apportioned. METHODS:318 patients attending the Black Dog Institute Depression Clinic ...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2012.05.051

    authors： Rhebergen D,Graham R,Hadzi-Pavlovic D,Stek M,Friend P,Barrett M,Parker G

    更新日期：2012-12-20 00:00:00

  • Altered plasma protein glycosylation in a mouse model of depression and in patients with major depression.

    abstract：BACKGROUND:Glycosylation is a common posttranslational modification in protein biosynthesis that is implicated in several disease states. It has been reported that specific protein glycan structures are useful as biomarkers for cancer and some neuropsychiatric diseases; however, the relationship between plasma protein ...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2017.08.057

    authors： Yamagata H,Uchida S,Matsuo K,Harada K,Kobayashi A,Nakashima M,Higuchi F,Watanuki T,Matsubara T,Watanabe Y

    更新日期：2018-06-01 00:00:00

  • Characterisation of the prodrome to a first episode of psychotic mania: results of a retrospective study.

    abstract：BACKGROUND:Little is known about the early phases of bipolar disorders (BPAD) and most of current knowledge derives from putative "high-risk" studies conducted in populations of bipolar off-spring; such information may therefore be relevant only to a sub-group of at-risk subjects. METHODS:Retrospective assessment of t...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2009.12.021

    authors： Conus P,Ward J,Lucas N,Cotton S,Yung AR,Berk M,McGorry PD

    更新日期：2010-08-01 00:00:00

  • Childhood trauma and depression in alcoholics: relationship to hostility.

    abstract：OBJECTIVE:To examine for a relationship between childhood trauma and depression in alcoholics. METHODS:Euthymic depressed alcoholics (N = 23) were compared with never depressed alcoholics (N = 20) for their scores on the Childhood Trauma Questionnaire (CTQ). Subjects also completed the Hostility and Direction of Hosti...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/s0165-0327(99)00044-0

    authors： Roy A

    更新日期：1999-12-01 00:00:00

  • Validation of a Chinese version of the short form of Metacognitions Questionnaire (MCQ-30).

    abstract：BACKGROUND:This study investigated the psychometric properties of a Chinese version of the short form of Metacognitions Questionnaire (MCQ-30), which is an effective tool to assess metacognitive beliefs that have been linked to mental disturbance/disorder. We also tested whether metacognition factors would correlate wi...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2020.08.028

    authors： Zhang MX,Lei LSM,Wells A,Dang L,Wu AMS

    更新日期：2020-12-01 00:00:00

  • Hormones and mood: from menarche to menopause and beyond.

    abstract：:The lifetime prevalence of mood disorders in women is approximately twice that of men. The underlying causality of this gender difference is not yet understood. There is increasing scientific attention to the modulation of the neuroendocrine system by fluctuating gonadal hormones. This review attempts to summarize our...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章,评审

    doi：10.1016/s0165-0327(02)00432-9

    authors： Steiner M,Dunn E,Born L

    更新日期：2003-03-01 00:00:00

  • Psychosocial work factors, major depressive and generalised anxiety disorders: results from the French national SIP study.

    abstract：BACKGROUND:Anxiety and depression are prevalent mental disorders in working populations. The risk factors of these disorders are not completely well known. Developing knowledge on occupational risk factors for mental disorders appears crucial. This study investigates the association between various classical and emerge...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2012.09.014

    authors： Murcia M,Chastang JF,Niedhammer I

    更新日期：2013-04-25 00:00:00

  • Premenstrual relapse of puerperal psychosis.

    abstract：:Eight patients suffering from puerperal psychosis rapidly recovered, then relapsed shortly before the onset of their first menstrual period; five of them had repeated premenstrual relapses. This clinical observation supports a hormonal aetiology for post-partum psychosis. ...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/0165-0327(88)90046-8

    authors： Brockington IF,Kelly A,Hall P,Deakin W

    更新日期：1988-05-01 00:00:00

  • Urinary steroid metabolites and 11beta-hydroxysteroid dehydrogenase activity in patients with unipolar recurrent major depression.

    abstract：BACKGROUND:The aim of the present study was to obtain comprehensive information on steroid metabolism in depressed patients. METHODS:24-h urinary steroids were measured by gas chromatography in patients with unipolar recurrent major depression (URMD) compared to controls, and an index of relative activity of the 11bet...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/S0165-0327(03)00199-X

    authors： Poór V,Juricskay S,Gáti A,Osváth P,Tényi T

    更新日期：2004-07-01 00:00:00

  • The psychological costs and benefits of being highly persistent: personality profiles distinguish mood disorders from anxiety disorders.

    abstract：BACKGROUND:The personality trait of Persistence is highly valued by conscientious overachievers, but it has both psychological costs and benefits. The interactions among multiple personality factors influencing the development of mood and anxiety disorders have been confounded in prior clinical samples, but can be dise...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2011.09.046

    authors： Cloninger CR,Zohar AH,Hirschmann S,Dahan D

    更新日期：2012-02-01 00:00:00

  • Prevalence and clinical correlates of co-occurring insomnia and hypersomnia symptoms in depression.

    abstract：BACKGROUND:The aim was to examine the prevalence and consequences of co-occurring insomnia and hypersomnia symptoms in depressed adults drawn from a representative sample of the U.S. population. METHOD:Data from 687 National Comorbidity Survey Replication (NCS-R) respondents meeting criteria for a major depressive epi...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2014.05.060

    authors： Soehner AM,Kaplan KA,Harvey AG

    更新日期：2014-01-01 00:00:00

  • Explicating the structure and relations of the Mood Disorder Questionnaire: Implications for screening for bipolar and related disorders.

    abstract：BACKGROUND:The Mood Disorder Questionnaire (MDQ; Hirschfeld et al., 2000) is a widely used screening measure in bipolar disorder research. Although this measure assesses a heterogeneous range of content, only limited prior research utilizing relatively small sample sizes has examined its factor structure. METHODS:The ...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2017.05.046

    authors： Stanton K,Watson D

    更新日期：2017-10-01 00:00:00

  • Cognitive styles and future depressed mood in early adulthood: the importance of global attributions.

    abstract：BACKGROUND:Cognitive theories of depression suggest that beliefs of low self-worth and the tendency to attribute negative events to causes that are global (widespread rather than specific) and stable (will persist rather than change in the future) are associated with the development of depressed mood. Such theories are...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2014.08.057

    authors： Pearson RM,Heron J,Button K,Bentall RP,Fernyhough C,Mahedy L,Bowes L,Lewis G

    更新日期：2015-01-15 00:00:00

  • Pediatric bipolar disorder in a Spanish sample: results after 2.6years of follow-up.

    abstract：INTRODUCTION:Bipolar disorder (BD) often starts in childhood or adolescence. There is considerable scepticism outside the United States over the validity, stability and prevalence of BD in children and adolescents. Persistence of course lends support to the validity of a diagnosis. OBJECTIVES:To describe the longitudi...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2011.01.013

    authors： Escamilla I,Wozniak J,Soutullo CA,Gamazo-Garrán P,Figueroa-Quintana A,Biederman J

    更新日期：2011-07-01 00:00:00

  • Secular trends in the rates and seasonality of violent and nonviolent suicide occurrences in Finland during 1980-95.

    abstract：BACKGROUND:Because secular trends in seasonality of different types of suicides has not been studied before, we utilized a novel statistical method to evaluate this phenomenon by using national Finnish suicide statistics during 1980-95. METHODS:Rates were analyzed with ordinary linear regression analysis. Secular tren...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/s0165-0327(98)00031-7

    authors： Hakko H,Räsänen P,Tiihonen J

    更新日期：1998-07-01 00:00:00

  • Frontoparietal function in young people with dysthymic disorder (DSM-5: Persistent depressive disorder) during spatial working memory.

    abstract：BACKGROUND:Dysthymic disorder (DD) is a depressive disorder characterised by persistent low and/or irritable mood and has been identified as a major risk factor for developing major depressive disorder (MDD). MDD and DD have been associated with executive function difficulties of working memory and attention. Little is...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2014.01.024

    authors： Vilgis V,Chen J,Silk TJ,Cunnington R,Vance A

    更新日期：2014-05-01 00:00:00

  • Genome-wide QTL analysis for anxiety trait in bipolar disorder type I.

    abstract：BACKGROUND:Genetic studies have been consistent that bipolar disorder type I (BPI) runs in families and that this familial aggregation is strongly influenced by genes. In a preliminary study, we proved that anxiety trait meets endophenotype criteria for BPI. METHODS:We assessed 619 individuals from the Central Valley ...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2017.12.019

    authors： Contreras J,Hare E,Chavarría-Soley G,Raventós H

    更新日期：2018-07-01 00:00:00

  • Psychostimulants for managing unipolar and bipolar treatment-resistant melancholic depression: a medium-term evaluation of cost benefits.

    abstract：BACKGROUND:We earlier reported an open study of 50 unipolar and bipolar treatment resistant depressed patients indicating that psychostimulants may have differential superiority for the melancholic depressive sub-type. We designed an extension study to examine cost benefits of psychostimulants more closely for those on...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2013.05.093

    authors： Parker G,Brotchie H,McClure G,Fletcher K

    更新日期：2013-10-01 00:00:00

  • Physical injury and depression in six low- and middle-income countries: A nationally representative study.

    abstract：BACKGROUND:Studies on the association between physical injury and depression in low- and middle-income countries (LMICs) are scarce. Therefore, our goal was to analyze the association between physical injury and depression using nationally representative data from six LMICs. METHODS:Cross-sectional data from the Study...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2019.01.023

    authors： Jacob L,Pizzol D,Veronese N,Stubbs B,Koyanagi A

    更新日期：2019-04-01 00:00:00

  • Predictive accuracy of the Post-Stroke Depression Prediction Scale: A prospective binational observational study✰.

    abstract：BACKGROUND:Depression after a stroke is a common complication that negatively influences stroke rehabilitation. Early identification, followed by adequate treatment of depression, improves recovery from stroke. To support early identification, the Post-stroke Depression Prediction Scale (DePreS) was developed to predic...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2020.01.019

    authors： Hirt J,van Meijeren LCJ,Saal S,Hafsteinsdóttir TB,Hofmeijer J,Kraft A,Meyer G,de Man-van Ginkel JM

    更新日期：2020-03-15 00:00:00

  • Depressive Symptoms among Junior High School Students in Southern China: Prevalence, Changes, and Psychosocial Correlates.

    abstract：BACKGROUND:Depression is one of the most common mental health problems in adolescents. A careful assessment of the prevalence and risk of depressive symptoms, as well as those factors that protect against it, is essential for prevention and intervention programs. METHOD:Using two waves of data from Grade 7 to Grade 9 ...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2020.05.034

    authors： Chi X,Liu X,Huang Q,Huang L,Zhang P,Chen X

    更新日期：2020-09-01 00:00:00

  • Predicting postnatal depression.

    abstract：BACKGROUND:The contribution that recently identified risk factors for Postnatal Depression (PND) made to an existing prenatal screening tool ('Predictive Index' of PND; Cooper et al., 1996) was assessed in an attempt to improve the performance of this measure. METHOD:The Predictive Index and measures of appraisal and ...

    journal_title：Journal of affective disorders

    pub_type： 临床试验,杂志文章

    doi：10.1016/s0165-0327(02)00085-x

    authors： Honey KL,Bennett P,Morgan M

    更新日期：2003-09-01 00:00:00

  • Borderline personality disorder, but not euthymic bipolar I disorder, is associated with prolonged post-error slowing in sensorimotor performance.

    abstract：BACKGROUND:Borderline personality disorder (BPD) and bipolar disorder (BD) are common psychiatric diagnoses. Impulsivity and affective instability are prominent features of both illnesses, complicate treatment and are associated with poor clinical outcomes. Yet, little is known about sensorimotor control in these popul...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2016.03.027

    authors： Saunders KE,Goodwin GM,Rogers RD

    更新日期：2016-07-01 00:00:00

  • Children with euthymic bipolar disorder during an emotional go/nogo task: Insights into the neural circuits of cognitive-emotional regulation.

    abstract：BACKGROUND:Pediatric bipolar disorder (PBD), manifested by alternating episodes of depression and mania, is more likely to relapse than adult BD and develop into chronic BD. Although it can be asymptomatic during the remission of PBD, subtle changes in the brain neural response can still exist. Abnormal activities in t...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2020.12.157

    authors： Xiao Q,Wu Z,Jiao Q,Zhong Y,Zhang Y,Lu G

    更新日期：2020-12-30 00:00:00

  • Subject-own-control design in evaluating clinical antidepressant effects.

    abstract：:This study tested the use of a subject-own-control, multiple crossover design for evaluating the clinical effects of an established tricyclic antidepressant drug, imipramine. Although significant physiological and cognitive performance effects were demonstrated, only one clinical measure, target symptom change rated b...

    journal_title：Journal of affective disorders

    pub_type： 临床试验,杂志文章

    doi：10.1016/0165-0327(82)90033-7

    authors： Glass RM,Uhlenhuth EH,Matuzas W,McCracken S,Greene S

    更新日期：1982-12-01 00:00:00

  • Temperament and character profile of college students who have suicidal ideas or have attempted suicide.

    abstract：OBJECTIVE:Suicide is a major cause of death in university students. Personality traits have been suggested as possible risk factors for suicidal behaviors. This study looked at the relationship between the personality dimensions of the Temperament and Character Inventory (TCI) and suicidal behaviors. METHOD:A total of...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2017.06.025

    authors： Lee K,Lee HK,Kim SH

    更新日期：2017-10-15 00:00:00

  • Adolescent stress and symptoms of anxiety and depression: Resilience explains and differentiates the relationships.

    abstract：BACKGROUND:Some adolescents exhibit resilience even in the face of high levels of stress exposure. Despite this relationship, studies that investigate explanations for how resilience interacts with risk to produce particular outcomes and why this is so are lacking. The effect of resilience across the relationship betwe...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2016.05.031

    authors： Anyan F,Hjemdal O

    更新日期：2016-10-01 00:00:00

  • The risk of Bipolar Disorders in Multiple Sclerosis.

    abstract：BACKGROUND:The aim was to determine the risk of Mood Disorders (MD), particularly Bipolar Disorders (BD), in Multiple Sclerosis (MS) using standardized psychiatric diagnostic tools. METHODS:Case-control study. CASES:201 consecutive-patients with MS. CONTROLS:804 sex- and age-matched subjects without MS, randomly sel...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2013.11.008

    authors： Carta MG,Moro MF,Lorefice L,Trincas G,Cocco E,Del Giudice E,Fenu G,Colom F,Marrosu MG

    更新日期：2014-02-01 00:00:00

  • Attempted and completed suicide: not what we expected?

    abstract：BACKGROUND:Suicide attempters and suicide completers are two overlapping but distinct suicide populations. This study aims to present a more accurate characterization by comparing populations of suicide attempters and completers from the same geographical area. METHODS:Samples and procedure: All cases of attempted sui...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2013.03.013

    authors： Parra Uribe I,Blasco-Fontecilla H,García-Parés G,Giró Batalla M,Llorens Capdevila M,Cebrià Meca A,de Leon-Martinez V,Pérez-Solà V,Palao Vidal DJ

    更新日期：2013-09-25 00:00:00

  • Impulsive suicide attempts: a systematic literature review of definitions, characteristics and risk factors.

    abstract：BACKGROUND:Extensive research on impulsive suicide attempts, but lack of agreement on the use of this term indicates the need for a systematic literature review of the area. The aim of this review was to examine definitions and likely correlates of impulsive attempts. METHODS:A search of Medline, Psychinfo, Scopus, Pr...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章,评审

    doi：10.1016/j.jad.2014.08.044

    authors： Rimkeviciene J,O'Gorman J,De Leo D

    更新日期：2015-01-15 00:00:00