Tyrosine-kinases in bacteria: from a matter of controversy to the status of key regulatory enzymes.

abstract：:This work proposes a strategy that uses solid-phase peptide synthesis associated with copper(I)-catalyzed azide alkyne cycloaddition reaction to promote the glycosylation of an antimicrobial peptide (HSP1) containing a carboxyamidated C-terminus (HSP1-NH2). Two glycotriazole-peptides, namely [p-Glc-trz-G1]HSP1-NH2 and...

journal_title：Amino acids

authors： Junior EFC,Guimarães CFRC,Franco LL,Alves RJ,Kato KC,Martins HR,de Souza Filho JD,Bemquerer MP,Munhoz VHO,Resende JM,Verly RM

更新日期：2017-08-01 00:00:00

abstract：:Neurofilaments (NFs) are integral constituents of the neuron playing a major role in brain development, maintenance, regeneration and the pattern of expression for NFs suggests their contribution to plasticity of the neuronal cytoskeleton and creating and maintaining neuronal architecture. Using immune-histochemical t...

journal_title：Amino acids

authors： Bajo M,Yoo BC,Cairns N,Gratzer M,Lubec G

更新日期：2001-01-01 00:00:00

abstract：:Peptide bonds in protein structures are mainly found in trans conformation with a torsion angle ω close to 180°. Only a very low proportion is observed in cis conformation with ω angle around 0°. Cis-trans isomerization leads to local conformation changes which play an important role in many biological processes. In t...

journal_title：Amino acids

authors： Craveur P,Joseph AP,Poulain P,de Brevern AG,Rebehmed J

更新日期：2013-08-01 00:00:00

abstract：:Rats were trained to perform a conditioned avoidance response to white noise in a conventional two-compartment "shuttle-box". The partition between the compartments had two openings, however, and the correct passage (leftor right) was signalled by changes in background illumination. In this situation the psychotomimet...

journal_title：Amino acids

authors： Ahlenius S,Ericson E,Svensson TH

更新日期：1992-02-01 00:00:00

abstract：:Blood-borne angiotensin II (AngII) is known to mediate water-intake by its excitatory effect on neurons in the subfornical organ (SFO). Conversely, nitric oxide (NO) has exclusively inhibitory effects on rat SFO-neurons and on SFO-mediated water-intake. Extracellular and patch-clamp recordings from freshly dissociated...

journal_title：Amino acids

authors： Schmid HA

更新日期：1998-01-01 00:00:00

abstract：:We determined the alterations in metabolic conversion of cysteine into glutathione and taurine in liver of rats treated with ethanol acutely. Ethanol treatment reduced cysteine as well as glutathione levels in liver for 24 h. However, cysteine dioxygenase was up-regulated rapidly, and hypotaurine/taurine levels were s...

journal_title：Amino acids

authors： Ahn CW,Kwon DY,Jun DS,Lee YM,Kim YC

更新日期：2015-06-01 00:00:00

abstract：:Selective removal of protecting groups under different cleavage mechanisms could be an asset in peptide synthesis, since it provides the feasibility to incorporate different functional groups in similar reactive centres. However, selective protection/deprotection of orthogonal protecting groups in peptides is still ch...

journal_title：Amino acids

authors： Stathopoulos P,Papas S,Sakka M,Tzakos AG,Tsikaris V

更新日期：2014-05-01 00:00:00

abstract：:Green tea which is widely consumed in China, Japan and India, contains polyphenolic compounds, which account for 30% of the dry weight of the leaves. Most of the polyphenols are flavanols, of which (-)-epigallocatechin-3-gallate (EGCG) is most abundant. Epidemiological studies revealed that the incidences of stomach a...

journal_title：Amino acids

authors： Bachrach U,Wang YC

更新日期：2002-01-01 00:00:00

abstract：:Thrombin, the most potent physiological platelet agonist interacts with cells through a specific G protein-coupled receptor which has been cloned and sequenced. Synthetic thrombin receptor peptides (TRAPs) comprising the first 5 amino acids (SFLLR and SFLLR-NH2) of the new N-terminus tethered ligand of the thrombin re...

journal_title：Amino acids

authors： Alexopoulos K,Matsoukas J,Tselios T,Roumelioti P,Mavromoustakos T,Holada K

更新日期：1998-01-01 00:00:00

abstract：:The purpose of the present study was to investigate the relationship between plasma carnitine concentration and body composition variation in relation to muscular and fat masses since there is no experimentally proved correlation between plasma carnitine and body masses. We used bioelectric impedance analysis (BIA), t...

journal_title：Amino acids

authors： Gatti R,De Palo CB,Spinella P,De Palo EF

更新日期：1998-01-01 00:00:00

abstract：:Relapse and metastasis are the main causes of unfavorable outcome in head and neck cancers. Whereas, understanding of the molecular background of these processes is far from being complete. Therefore, in this study we aimed to identify potential biomarker candidates of relapse and metastasis in laryngeal squamous cell...

journal_title：Amino acids

authors： Bodnar M,Luczak M,Bednarek K,Szylberg L,Marszalek A,Grenman R,Szyfter K,Jarmuz-Szymczak M,Giefing M

更新日期：2016-06-01 00:00:00

abstract：:Glutamate dehydrogenase (GDH) plays a crucial role in amino acid deamination and has been used as an inductor of nutrients metabolism. In this study, we cloned and analyzed the GDH cDNAs in diploids (red crucian carp), triploids and tetraploids and characterized their expression profiles upon dietary treatments. Resul...

journal_title：Amino acids

authors： Liu Z,Zhou Y,Liu S,Zhong H,Zhang C,kang X,Liu Y

更新日期：2012-12-01 00:00:00

abstract：:Both 1,4-benzoquinones and 1,4-naphthoquinones were attached to the non-proteinogenic amino acid taurine to form N-quinonyl taurine derivatives. The products were formed via the direct Michael-like addition or by substitution of a good leaving group. An attempt to bridge the two moieties via an ureido spacer resulted ...

journal_title：Amino acids

authors： Gorohovsky S,Temtsin-Krayz G,Bittner S

更新日期：2003-04-01 00:00:00

abstract：:Recently, we observed that central administration of L-arginine attenuated stress responses in neonatal chicks, but the contribution of nitric oxide (NO) to this response was minimal. The sedative and hypnotic effects of L-arginine may be due to L-arginine itself and/or its metabolites, excluding NO. To clarify the me...

journal_title：Amino acids

authors： Suenaga R,Yamane H,Tomonaga S,Asechi M,Adachi N,Tsuneyoshi Y,Kurauchi I,Sato H,Denbow DM,Furuse M

更新日期：2008-06-01 00:00:00

abstract：:The cellular amino acid composition of plant cells was analyzed. The callus of carrot (Daucus carota), leaves of Torenia fournieri and protocomb-like body of Cymbidium, s.p. were examined as examples of plant cells. The cellular amino acid compositions differed in the plant cells, but their basic patterns were quite s...

journal_title：Amino acids

authors： Sorimachi K,Okayasu T,Akimoto K,Niwa A

更新日期：2000-01-01 00:00:00

abstract：:Elevated plasma concentrations of asymmetric dimethylarginine (ADMA) and symmetric dimethylarginine (SDMA) were found in various clinical settings including coronary heart disease. To assess ADMA and SDMA diagnostic validity in patients with different stages of ischemic heart disease, we studied these markers in patie...

journal_title：Amino acids

authors： Djordjević BV,Pavlović R,Ćosić V,Deljanin-Ilić M,Ristić T,Krstić N,Jevtović-Stoimenov T

更新日期：2012-12-01 00:00:00

abstract：:How to enhance fruit tolerance to cold stress is an important biological interest. In this paper, we found that mango (Mangifera indica L.) fruit treated with 10 μM brassinolide (BL) showed a higher tolerance to cold temperature of 5 °C. Further, we compared the changes in expression profiles of plasma membrane (PM) p...

journal_title：Amino acids

authors： Li B,Zhang C,Cao B,Qin G,Wang W,Tian S

更新日期：2012-12-01 00:00:00

abstract：:We have been studying control mechanisms of gene expression in early embryogenesis in a South African clawed toad Xenopus laevis, especially during the period of midblastula transition (MBT), or the transition from the phase of active cell division (cleavage stage) to the phase of extensive morphogenesis (post-blastul...

journal_title：Amino acids

authors： Shiokawa K,Aso M,Kondo T,Takai J,Yoshida J,Mishina T,Fuchimukai K,Ogasawara T,Kariya T,Tashiro K,Igarashi K

更新日期：2010-02-01 00:00:00

abstract：:Reports on nucleobase-containing chiral peptides (both natural and artificial) and achiral pseudopeptides are reviewed. Their synthesis, structural features, DNA and RNA-binding ability, as well as some other interesting applications which make them promising diagnostic/therapeutic agents of great importance in many a...

journal_title：Amino acids

authors： Roviello GN,Benedetti E,Pedone C,Bucci EM

更新日期：2010-06-01 00:00:00

abstract：:In the absence of exogenous Ca(2+) and Mg(2+) and in the presence of EGTA, which favours the release of endogenous Ca(2+), the polyamine spermine is able to stimulate the activity of pyruvate dehydrogenase complex (PDC) of energized rat liver mitochondria (RLM). This stimulation exhibits a gradual concentration-depend...

journal_title：Amino acids

authors： Pezzato E,Battaglia V,Brunati AM,Agostinelli E,Toninello A

更新日期：2009-03-01 00:00:00

abstract：:Glycation, or non-enzymatic glycosylation, is a common protein modification formed by reactions between reducing sugars (i.e. aldoses and ketoses) with protein amino groups. Resulting Amadori and Heyns compounds, respectively, can be oxidatively degraded yielding a structurally heterogeneous group of advanced glycatio...

journal_title：Amino acids

authors： Greifenhagen U,Frolov A,Hoffmann R

更新日期：2015-05-01 00:00:00

abstract：:Vascular smooth muscle cells (SMC) are able to proliferate when cultured on plates, but become differentiated when maintained in three-dimensional type I collagen matrices (honeycombs). SMC grown in honeycombs contained a low level of polyamines due to the presence of antizyme 1 (AZ1), a negative regulator of ornithin...

journal_title：Amino acids

authors： Ishii I,Suzuki T,Kaneko H,Uchida M,Suzuki Y,Higashi K,Yagi S,Ariyoshi N,Igarashi K,Kitada M

更新日期：2012-02-01 00:00:00

abstract：:Numerous indolyl amino acids and their derivatives inhibited arginase activity. The inhibition was found to be non-competitive, - at least partly - allosteric, and independent on manganese ions in the active site, and it cannot be explained by the dissociation of arginase homotrimers. Indole alone is weakly inhibitory...

journal_title：Amino acids

authors： Hrabák A,Bajor T,Mészáros G

更新日期：2008-02-01 00:00:00

abstract：:Proteins with polybasic clusters bind to negatively charged phosphoinositides at the cell membrane. In this review, I have briefly discussed the types of phosphoinositides naturally found on membrane surfaces and how they recruit protein complexes for carrying out the process of signal transduction. A large number of ...

journal_title：Amino acids

authors： Gokhale NA

更新日期：2013-10-01 00:00:00

abstract：:Taurine is found in bone tissue, but its function in skeletal tissue is not fully understood. The present study was undertaken to investigate regulation of gene expression of connective tissue growth factor (CTGF), and the roles of mitogen-activated protein kinases (MAPKs) in murine osteoblast MC3T3-E1 cells treated w...

journal_title：Amino acids

authors： Yuan LQ,Lu Y,Luo XH,Xie H,Wu XP,Liao EY

更新日期：2007-01-01 00:00:00

abstract：:In a previous study, we elucidated the apoptotic mechanism mediated via Fas/FasL-dependent pathway in mitomycin C-treated cervical carcinoma cells. In this study, 2-D and MALDI-TOF analyses were performed in order to search mitomycin C-induced modulators in cervical carcinoma cells. Some protein spots down- or up-regu...

journal_title：Amino acids

authors： Kang YH,Lee KA,Kim JH,Park SG,Yoon DY

更新日期：2010-11-01 00:00:00

abstract：:The study was designed to investigate the effects of NMDA receptor agonist on the behavioral activity in rats with experimental hyperammonemia. The experiments were performed on adult male Wistar rats. Experimental hyperammonemia was induced by intraperitoneal injections of tioacetamide (TAA, 200 mg/kg) for three cons...

journal_title：Amino acids

authors： Fedosiewicz-Wasiluk M,Hoły ZZ,Wiśniewska RJ,Wiśniewski K

更新日期：2005-02-01 00:00:00

abstract：:The lysine catabolism pathway differs in adult mammalian brain from that in extracerebral tissues. The saccharopine pathway is the predominant lysine degradative pathway in extracerebral tissues, whereas the pipecolate pathway predominates in adult brain. The two pathways converge at the level of ∆(1)-piperideine-6-ca...

journal_title：Amino acids

authors： Hallen A,Jamie JF,Cooper AJ

更新日期：2013-12-01 00:00:00

abstract：:The enzymes Akt, mTOR, p70(S6K), rpS6, GSK3, and glycogen synthase interact in the control of protein and/or glycogen synthesis in skeletal muscle, and each has been found to respond to exercise and nutrient supplementation. In the present study, we tested the hypothesis that nutrient supplementation post exercise, in...

journal_title：Amino acids

authors： Ivy JL,Ding Z,Hwang H,Cialdella-Kam LC,Morrison PJ

更新日期：2008-06-01 00:00:00

abstract：:In the postgenomic era new technologies are emerging for global analysis of protein function. The introduction of active site-directed chemical probes for enzymatic activity profiling in complex mixtures, known as activity-based proteomics has greatly accelerated functional annotation of proteins. Here we review probe...

journal_title：Amino acids

authors： Schmidinger H,Hermetter A,Birner-Gruenberger R

更新日期：2006-06-01 00:00:00