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Identification and functional analysis of brassicicene C biosynthetic gene cluster in Alternaria brassicicola.

Abstract：

:The biosynthetic gene cluster of brassicicene C was identified in Alternaria brassicicola strain ATCC 96836 from genome database search. In vivo and in vitro study clearly revealed the function of Orf8 and Orf6 as a fusicoccadiene synthase and methyltransferase, respectively. The understanding toward the biosynthetic pathway promises construction of this type of diterpene compounds with genetic engineering.

journal_name

Bioorg Med Chem Lett

journal_title

Bioorganic & medicinal chemistry letters

authors

Minami A,Tajima N,Higuchi Y,Toyomasu T,Sassa T,Kato N,Dairi T

doi

10.1016/j.bmcl.2008.11.108

subject

Has Abstract

pub_date

2009-02-01 00:00:00

pages

870-4

issue

3

eissn

0960-894X

issn

1464-3405

pii

S0960-894X(08)01494-7

journal_volume

19

pub_type

杂志文章

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