Epicubenol synthase. Origin of the oxygen atom of a bacterial sesquiterpene alcohol.

Abstract:

:Incubation of epicubenol synthase with farnesyl pyrophosphate in the presence of 11.1 atom% H2(18)O gave epicubenol (2) in which the hydroxyl oxygen atom was shown to be derived exclusively from water, as established by GC-selected ion monitoring MS of the derived TMS-epicubenol derivative (15).

journal_name

Bioorg Med Chem Lett

authors

Cane DE,Ke N

doi

10.1016/s0960-894x(99)00650-2

subject

Has Abstract

pub_date

2000-01-17 00:00:00

pages

105-7

issue

2

eissn

0960-894X

issn

1464-3405

pii

S0960-894X(99)00650-2

journal_volume

10

pub_type

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