Abstract:
:Epstein-Barr virus (EBV) associated central nervous system (CNS) infection is a rare disease. We report an atypical manifestation of EBV encephalitis initially presenting with a tumor-like lesion of the optic tract in an immunocompromised patient 8 years after a combined kidney and pancreas transplantation had been performed. Polymerase chain reaction (PCR) in the cerebrospinal fluid (CSF) and antibody testing confirmed the diagnosis of EBV encephalitis, most likely as a consequence of a reactivated persistent EBV infection. After cessation of the immunosuppressive therapy and induction of treatment with ganciclovir, clinical and magnetic resonance imaging (MRI) findings rapidly improved.
journal_name
J Neuroviroljournal_title
Journal of neurovirologyauthors
Khalil M,Enzinger C,Wallner-Blazek M,Scarpatetti M,Barth A,Horn S,Reiter Gdoi
10.1080/13550280802345715subject
Has Abstractpub_date
2008-11-01 00:00:00pages
574-8issue
6eissn
1355-0284issn
1538-2443pii
905134730journal_volume
14pub_type
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