Epstein-Barr virus encephalitis presenting with a tumor-like lesion in an immunosuppressed transplant recipient.

Abstract:

:Epstein-Barr virus (EBV) associated central nervous system (CNS) infection is a rare disease. We report an atypical manifestation of EBV encephalitis initially presenting with a tumor-like lesion of the optic tract in an immunocompromised patient 8 years after a combined kidney and pancreas transplantation had been performed. Polymerase chain reaction (PCR) in the cerebrospinal fluid (CSF) and antibody testing confirmed the diagnosis of EBV encephalitis, most likely as a consequence of a reactivated persistent EBV infection. After cessation of the immunosuppressive therapy and induction of treatment with ganciclovir, clinical and magnetic resonance imaging (MRI) findings rapidly improved.

journal_name

J Neurovirol

journal_title

Journal of neurovirology

authors

Khalil M,Enzinger C,Wallner-Blazek M,Scarpatetti M,Barth A,Horn S,Reiter G

doi

10.1080/13550280802345715

subject

Has Abstract

pub_date

2008-11-01 00:00:00

pages

574-8

issue

6

eissn

1355-0284

issn

1538-2443

pii

905134730

journal_volume

14

pub_type

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