当前位置： SCI文献检索 > BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS期刊下所有文献 > MINK is a Rap2 effector for phosphorylation of the postsynaptic scaffold protein TANC1.

MINK is a Rap2 effector for phosphorylation of the postsynaptic scaffold protein TANC1.

Abstract：

:Rap1 and Rap2 are similar Ras-like G proteins but perform distinct functions. By the affinity chromatography/mass-spectrometry approach and the yeast two-hybrid screening, we identified Misshapen/NIKs-related kinase (MINK) as a novel Rap2-interacting protein that does not interact with Rap1 or Ras. MINK is a member of the STE20 group of mitogen-activated protein kinase kinase kinase kinases. The interaction between MINK and Rap2 was GTP-dependent and required Phe39 within the effector region of Rap2; the corresponding residue in Rap1 and Ras is Ser. MINK was enriched in the brain, and both MINK and its close relative, Traf2- and Nck-interacting kinase (TNIK), interacted with a postsynaptic scaffold protein containing tetratricopeptide repeats, ankyrin repeats and a coiled-coil region (TANC1) and induced its phosphorylation, under control of Rap2 in cultured cells. These are novel actions of MINK and TNIK, and consistent with a role of MINK as a Rap2 effector in the brain.

journal_name

Biochem Biophys Res Commun

journal_title

Biochemical and biophysical research communications

authors

Nonaka H,Takei K,Umikawa M,Oshiro M,Kuninaka K,Bayarjargal M,Asato T,Yamashiro Y,Uechi Y,Endo S,Suzuki T,Kariya KI

doi

10.1016/j.bbrc.2008.10.038

subject

Has Abstract

pub_date

2008-12-12 00:00:00

pages

573-578

issue

2

eissn

0006-291X

issn

1090-2104

pii

S0006-291X(08)01982-7

journal_volume

377

pub_type

杂志文章

相关文献

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS文献大全
  • Heart fatty acid binding protein is a novel regulator of cardiac myocyte hypertrophy.

    abstract：:Heart fatty acid binding protein (H-FABP) is a 15kDa protein that mediates the passage of fatty acids from the plasma membrane to sites of lipid synthesis. We report here, for the first time, that H-FABP is a potent inducer of cardiac myocyte hypertrophy, stimulating an increase in cell surface area, protein synthesis...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.1994.2882

    authors： Burton PB,Hogben CE,Joannou CL,Clark AG,Hsuan JJ,Totty NF,Sorensen C,Evans RW,Tynan MJ

    更新日期：1994-12-30 00:00:00

  • Molecular and phenotypic reassessment of an infrequently used mouse model for spinal muscular atrophy.

    abstract：:Proximal spinal muscular atrophy (SMA) results from loss of the survival motor neuron 1 (SMN1) gene, with retention of its nearly identical homolog, SMN2. There is a direct correlation between disease severity and SMN2 copy number. Mice do not have a Smn2 gene, and thus cannot naturally replicate the disorder. However...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2009.11.090

    authors： Gogliotti RG,Hammond SM,Lutz C,Didonato CJ

    更新日期：2010-01-01 00:00:00

  • Isolation and characterization of monoclonal antibodies against ribonuclease inhibitor.

    abstract：:Mouse monoclonal antibodies were generated against human ribonuclease inhibitor, an intracellular regulatory protein. A total of four antibodies were isolated, all of which were of the immunoglobulin G1 subtype. Western blot analysis of the antibodies suggested monospecificity. Based on immunoradiometric competition a...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/s0006-291x(88)80045-7

    authors： Feldman M,Kohtz DS,Kleinberg DL

    更新日期：1988-11-30 00:00:00

  • N-methyl-N-nitrosourea evidences cell cycle associated transient sequences in hepatic replicating DNA.

    abstract：:Experiments of molecular hybridization were carried out with the aim of singling out DNA sequences which might be important in the hepatocarcinogenic action of N-methyl-N-nitrosourea. Results were obtained suggesting the synthesis of transitory DNA sequences during compensatory cell proliferation. ...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.1995.1367

    authors： Kanduc D

    更新日期：1995-03-17 00:00:00

  • Alpha-lipoic acid reduces retinal cell death in diabetic mice.

    abstract：:Oxidative stress plays an important role in the development of diabetic retinopathy. Here, we examined whether α-lipoic acid (α-LA), a natural antioxidant, attenuated retinal injury in diabetic mice. The α-LA was orally administered to control mice or mice with streptozotocin-induced diabetes. We found that α-LA reduc...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2018.07.041

    authors： Kim YS,Kim M,Choi MY,Lee DH,Roh GS,Kim HJ,Kang SS,Cho GJ,Hong EK,Choi WS

    更新日期：2018-09-10 00:00:00

  • Expression of human inducible nitric oxide synthase is regulated by both promoter and 3'-regions.

    abstract：:One of the mechanisms underlying the induction of human inducible nitric oxide synthase (hiNOS) by cytokines is transcriptional regulation. However, previous reports suggest that in human cells, the cytokine activation of the hiNOS expression is accompanied by a drastic increase in cellular mRNA and protein content, b...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.1997.6471

    authors： Nunokawa Y,Oikawa S,Tanaka S

    更新日期：1997-04-17 00:00:00

  • Diversity within the JMJD2 histone demethylase family.

    abstract：:JMJD2A-D belong to the JmjC domain-containing family of histone demethylases. JMJD2D is the most structurally divergent JMJD2 protein as it lacks the PHD and Tudor domains present in JMJD2A-C. Here, we systematically analyzed the histone demethylase specificity of JMJD2 proteins in vivo. We found that JMJD2A and C dem...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2006.12.147

    authors： Shin S,Janknecht R

    更新日期：2007-02-23 00:00:00

  • The real factor for polypeptide elongation in Dictyostelium cells is EF-2B, not EF-2A.

    abstract：:Polypeptide elongation factor 2 (EF-2) plays an essential role in protein synthesis and is believed to be indispensable for cell proliferation. Recently, it has been demonstrated that there are two kinds of EF-2 (EF-2A and EF-2B with 76.6% of sequence identity at the amino acid level) in Dictyostelium discoideum. Alth...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2007.05.155

    authors： Yoshino T,Maeda Y,Amagai A

    更新日期：2007-08-03 00:00:00

  • Synergistic potentiation of thiazolidinedione-induced ST 13 preadipocyte differentiation by RAR synergists.

    abstract：:Peroxisome proliferator-activated receptor gamma (PPAR gamma) belongs to a nuclear receptor super family that functions as a master regulator of adipocyte differentiation. PPAR gamma binds its DNA response element together with a partner, retinoid X receptor (RXR), in fat cells. Five RXR ligands (HX600, HX630, DA022, ...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.2000.4172

    authors： Sato M,Yajima Y,Kawashima S,Tanaka K,Kagechika H

    更新日期：2001-01-26 00:00:00

  • Aryl hydrocarbon receptor catabolic activity in bone metabolism is osteoclast dependent in vivo.

    abstract：:Bone mass is regulated by various molecules including endogenous factors as well as exogenous factors, such as nutrients and pollutants. Aryl hydrocarbon receptor (AhR) is known as a dioxin receptor and is responsible for various pathological and physiological processes. However, the role of AhR in bone homeostasis re...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2014.05.114

    authors： Yu TY,Kondo T,Matsumoto T,Fujii-Kuriyama Y,Imai Y

    更新日期：2014-07-18 00:00:00

  • Characterizing the structural and thermodynamic properties of Aβ42 and Aβ40.

    abstract：:The self-assembly of amyloid-beta (Aβ) proteins in aqueous extracellular environments is implicated in Alzheimer's disease. Among several alloforms of Aβ proteins differing in sequence length, the 42- and 40-residue forms (Aβ42 and Aβ40) are the most abundant ones in the human body. Although the only difference is the...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2019.01.124

    authors： Lin Y,Im H,Diem LT,Ham S

    更新日期：2019-03-12 00:00:00

  • AtVps11 is essential for vacuole biogenesis in embryo and participates in pollen tube growth in Arabidopsis.

    abstract：:Vacuoles are multiple functional and essential organelles in plants. Studies in Saccharomyces cerevisiae had identified a tethering factor HOPS (Homotypic Fusion and Vacuolar Protein Sorting) complex that plays a critical role in vacuole biogenesis. The HOPS complex consists of four core subunits (Vps11, Vps16, Vps18 ...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2017.07.059

    authors： Tan X,Wei J,Li B,Wang M,Bao Y

    更新日期：2017-09-23 00:00:00

  • The HMGB1 acidic tail regulates HMGB1 DNA binding specificity by a unique mechanism.

    abstract：:HMGB1 is a conserved chromosomal protein composed of two DNA-binding domains and an acidic C-terminal tail. There were evidences suggesting that the C-terminal tail contributed to the DNA binding specificity of the N-terminal DNA-binding domains. However, the mechanism underlining this observation is largely unknown. ...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2007.05.130

    authors： Wang Q,Zeng M,Wang W,Tang J

    更新日期：2007-08-17 00:00:00

  • Ethanol feeding induces insulin resistance with enhanced PI 3-kinase activation.

    abstract：:High ethanol intake is considered to impair insulin sensitivity. In the present study, we investigated the acute and chronic effects of ethanol intake on glucose metabolism and insulin signal transduction. Hyperinsulinemic-euglycemic clamp studies revealed 70% and 51% decreases in the glucose infusion rate, 52% and 31...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/s0006-291x(03)00407-8

    authors： Onishi Y,Honda M,Ogihara T,Sakoda H,Anai M,Fujishiro M,Ono H,Shojima N,Fukushima Y,Inukai K,Katagiri H,Kikuchi M,Oka Y,Asano T

    更新日期：2003-04-11 00:00:00

  • Tissue factor expression on monocytes induced by anti-phospholipid antibodies as a strong risk factor for thromboembolic complications in SLE patients.

    abstract：:Our aim was to clarify the role of anti-phospholipid antibodies in the pathogenesis of monocyte tissue factor (TF) expression and thromboembolic complications (TE) in patients with SLE. We examined cell surface expression of TF on monocytes in 93 SLE patients. Monocyte TF expression was significantly higher in SLE pat...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2007.10.173

    authors： Nojima J,Masuda Y,Iwatani Y,Suehisa E,Futsukaichi Y,Kuratsune H,Watanabe Y,Takano T,Hidaka Y,Kanakura Y

    更新日期：2008-01-04 00:00:00

  • Molecular force spectroscopy of homophilic nectin-1 interactions.

    abstract：:Nectins are Ca2+ independent cell adhesion molecules localizing at the cadherin based adherens junctions. In this study, we have used atomic force microscopy to study interaction of a chimera of extra cellular fragment of nectin-1 and Fc of human IgG (nef-1) with wild type L-fibroblasts that express endogenous nectin-...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2007.08.096

    authors： Vedula SR,Lim TS,Hui S,Kausalya PJ,Lane EB,Rajagopal G,Hunziker W,Lim CT

    更新日期：2007-11-03 00:00:00

  • Epithelial Na+ channel and ion transport in human nasal polyp and paranasal sinus mucosa.

    abstract：:The purpose of the present study is to characterize the ENaC-mediated Na+ absorption in human upper airway epithelia, nasal cavity, and paranasal sinus. To perform the purpose, we obtained epithelial cells from human nasal polyp (NP) and paranasal sinus mucosa (PSM) by endoscopic surgery. We measured the short-circuit...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2007.08.065

    authors： Yasuda M,Niisato N,Miyazaki H,Iwasaki Y,Hama T,Dejima K,Hisa Y,Marunaka Y

    更新日期：2007-10-26 00:00:00

  • Identification and functional characterization of three type III polyketide synthases from Aquilaria sinensis calli.

    abstract：:Type III polyketide synthases (PKSs) play an important role in biosynthesis of various plant secondary metabolites and plant adaptation to environmental stresses. Aquilaria sinensis (A. sinensis) is the main plant species for production of agarwood, little is known about its PKS family. In this study, AsCHS1 and two n...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2017.03.159

    authors： Wang X,Zhang Z,Dong X,Feng Y,Liu X,Gao B,Wang J,Zhang L,Wang J,Shi S,Tu P

    更新日期：2017-05-13 00:00:00

  • In vivo characterisation of the human UCP3 gene minimal promoter in mice tibialis anterior muscles.

    abstract：:Transcriptional mechanisms controlling human UCP3 gene expression in skeletal muscle remain poorly understood. Experiments based on plasmid electrotransfer into tibialis anterior muscle of C57/BL6 male mice were set up in order to functionally analyze the hUCP3 gene promoter. These transfection experiments showed that...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2003.10.034

    authors： Riquet FB,Rodriguez M,Guigal N,Dromaint S,Naime I,Boutin JA,Galizzi JP

    更新日期：2003-11-21 00:00:00

  • Inflammatory mediator bradykinin increases population of sensory neurons expressing functional T-type Ca(2+) channels.

    abstract：:T-type Ca(2+) channels are important regulators of peripheral sensory neuron excitability. Accordingly, T-type Ca(2+) currents are often increased in various pathological pain conditions, such as inflammation or nerve injury. Here we investigated effects of inflammation on functional expression of T-type Ca(2+) channe...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2016.02.118

    authors： Huang D,Liang C,Zhang F,Men H,Du X,Gamper N,Zhang H

    更新日期：2016-04-29 00:00:00

  • The same nuclear proteins bind the proximal CACCC box of the human beta-globin promoter and a similar sequence in the enhancer.

    abstract：:Using in vitro assays, we show that nuclear proteins related to the Sp1 and GT-1 factors bind to a CACCC box sequence in the human beta-globin enhancer, adjacent to binding sites for the erythroid-specific factor NFE1 and the ubiquitous factor CP1. The same proteins are known to bind to the proximal, but not to the di...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/0006-291x(89)91695-1

    authors： Giglioni B,Comi P,Ronchi A,Mantovani R,Ottolenghi S

    更新日期：1989-10-16 00:00:00

  • GTP-binding membrane proteins in activated and differentiating T cells.

    abstract：:We have earlier reported changes in the GTP binding of several membrane proteins including Gs alpha and Gi alpha during thymic differentiation of T cells. Using an [alpha-32P]GTP-photoaffinity labeling technique we have studied the pattern of GTP binding proteins in activated and resting T lymphocytes and in T cells i...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/0006-291x(91)91790-j

    authors： Pessa-Morikawa T,Nordström T,Mustelin T,Andersson LC

    更新日期：1991-07-15 00:00:00

  • Effects of D- and L-thyroxine on the glucocorticoid binding capacity of adult rat liver.

    abstract：:Administration of either D- or L-thyroxine (T4) significantly increased the glucocorticoid binding capacity of cytosol of the livers of adrenalectomized adult rats. Administration of up to 0.5 mg/100 g body wt. of L-T4 was more effective than that of D-T4, but higher doses (0.8-3 mg/100 g body wt.) of D-T4 increased t...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/0006-291x(85)90171-8

    authors： Naito K,Isohashi F,Tsukanaka K,Horiuchi M,Okamoto K,Matsunaga T,Sakamoto Y

    更新日期：1985-06-14 00:00:00

  • Allergic asthma aggravated atherosclerosis increases cholesterol biosynthesis and foam cell formation in apolipoprotein E-deficient mice.

    abstract：:Several studies have demonstrated that allergic asthma can induce atherosclerosis formation in mice. Moreover, allergic asthma and atherosclerosis have been shown to be strongly associated with dyslipidemia. In this study, we investigated the underlying mechanism of allergic asthma-aggravated atherosclerosis-induced c...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2019.09.085

    authors： Gao S,Wang C,Li W,Shu S,Zhou J,Yuan Z,Wang L

    更新日期：2019-11-19 00:00:00

  • Purification of the mitochondrial citrate transporter in yeast.

    abstract：:We present a method of partial purification of mitochondrial citrate transporter of the yeast Saccharomyces cerevisiae. Based on functional evidence of interaction between citrate transport and citrate synthase, we have used an affinity column containing pig heart citrate synthase (PHCS) for the purification. The puri...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/0006-291x(92)91610-3

    authors： Persson LO,Srere PA

    更新日期：1992-02-28 00:00:00

  • 2,3,7,8-Tetrachlorodibenzo-p-dioxin increases reliance on fats as a fuel source independently of diet: evidence that diminished carbohydrate supply contributes to dioxin lethality.

    abstract：:The environmental toxin, 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) causes a wasting syndrome marked by hypophagia, loss of body fat, changes in intermediary metabolism and death. Use of conventional laboratory animals has not resolved whether or not TCDD affects intermediary metabolism independently of hypophagia. We...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/0006-291x(91)91558-t

    authors： Lentnek M,Griffith OW,Rifkind AB

    更新日期：1991-02-14 00:00:00

  • MicroRNA-26a modulates transforming growth factor beta-1-induced proliferation in human fetal lung fibroblasts.

    abstract：:MicroRNA-26a is a newly discovered microRNA that has a strong anti-tumorigenic capacity and is capable of suppressing cell proliferation and activating tumor-specific apoptosis. However, whether miR-26a can inhibit the over-growth of lung fibroblasts remains unclear. The relationship between miR-26a and lung fibrosis ...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2014.10.106

    authors： Li X,Liu L,Shen Y,Wang T,Chen L,Xu D,Wen F

    更新日期：2014-11-28 00:00:00

  • Escherichia coli outer membrane protein A adheres to human brain microvascular endothelial cells.

    abstract：:Escherichia coli K1 is the most common gram-negative bacterium causing neonatal meningitis. The outer membrane protein A (OmpA) assembles a beta-barrel structure having four surface-exposed loops in E. coli outer membrane. OmpA of meningitis-causing E. coli K1 is shown to contribute to invasion of the human brain micr...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2005.03.097

    authors： Shin S,Lu G,Cai M,Kim KS

    更新日期：2005-05-20 00:00:00

  • Functional characterization of a novel Cx26 (T55N) mutation associated to non-syndromic hearing loss.

    abstract：:Mutations of the GJB2 gene, encoding connexin 26, are the most common cause of hereditary congenital hearing loss in many countries and account for up to 50% of cases of autosomal-recessive non-syndromic deafness. By contrast, only a few GJB2 mutations have been reported to cause an autosomal-dominant form of non-synd...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2005.09.116

    authors： Melchionda S,Bicego M,Marciano E,Franzè A,Morgutti M,Bortone G,Zelante L,Carella M,D'Andrea P

    更新日期：2005-11-25 00:00:00

  • Internalization of MUC1 by anti-MUC1 antibody from cell membrane through the macropinocytotic pathway.

    abstract：:MUC1 is a type I transmembrane glycoprotein aberrantly overexpressed in various cancer cells. It is thought to serve as a physical barrier from the extracellular environment and also as a receptor for various extracellular molecules. However, little is known about the fate of MUC1 during and after the interaction with...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2009.08.059

    authors： Hisatsune A,Kawasaki M,Nakayama H,Mikami Y,Miyata T,Isohama Y,Katsuki H,Kim KC

    更新日期：2009-10-30 00:00:00