Abstract:
PURPOSE OF REVIEW:To raise awareness of and inform evidence-based practice regarding medical and behavioral interventions for antipsychotic medication-induced metabolic abnormalities. RECENT FINDINGS:The current literature indicates that individuals with severe and persistent mental illness have significantly worse health outcomes and premature mortality than the general population, owing to a combination of under-recognition and treatment of medical risk factors, reduced access to care, sedentary lifestyle and poor diet, and the potential contribution of adverse metabolic side effects of antipsychotic medications such as weight gain, hyperglycemia and dyslipidemia. A combination of administrative, behavioral and medical approaches to addressing these medical risks may be more effective than any one of these approaches alone. SUMMARY:Treatment with antipsychotic medications can induce significant weight gain and abnormalities in lipid and glucose metabolism that increase risk for cardiovascular disease and diabetes in a population already at risk from multiple other sources. Managing the side effects of antipsychotics and lowering risk in general is an important aspect of the management of chronic mental illness. There are a variety of effective medical and behavioral interventions that can be employed to achieve primary and secondary prevention aims.
journal_name
Curr Opin Psychiatryjournal_title
Current opinion in psychiatryauthors
Amiel JM,Mangurian CV,Ganguli R,Newcomer JWdoi
10.1097/YCO.0b013e328314b74bsubject
Has Abstractpub_date
2008-11-01 00:00:00pages
613-8issue
6eissn
0951-7367issn
1473-6578pii
00001504-200811000-00016journal_volume
21pub_type
杂志文章,评审abstract:PURPOSE OF REVIEW:This review covers the epidemiological research from developing countries to identify the scope of research in the various aspects of epidemiology and the strengths of research. The period covered is June 2004 to June 2005. The literature survey used searches of Medline, key psychiatric journals and p...
journal_title:Current opinion in psychiatry
pub_type: 杂志文章
doi:10.1097/01.yco.0000179499.23311.f3
更新日期:2005-09-01 00:00:00
abstract:PURPOSE OF REVIEW:To consider comorbidity across multiple classes of disorders in data derived from recent large-scale community surveys. RECENT FINDINGS:There has been substantial recent progress in our understanding of patterns and implications of comorbidity of mental disorders. There is now converging evidence on ...
journal_title:Current opinion in psychiatry
pub_type: 杂志文章,评审
doi:10.1097/YCO.0b013e3281c61dc5
更新日期:2007-07-01 00:00:00
abstract:PURPOSE OF REVIEW:To understand pathways into healthcare people of minority ethnic groups use and if these differ from those of the majority. RECENT FINDINGS:The current literature shows that some forms of treatment are seen as less stigmatizing and more acceptable. The treatment expectations also dictate choice of he...
journal_title:Current opinion in psychiatry
pub_type: 杂志文章,评审
doi:10.1097/YCO.0b013e3283477ae8
更新日期:2011-07-01 00:00:00
abstract:PURPOSE OF REVIEW:This article reviews recent literature published over the period March 2012-August 2013 on antidepressant pharmacogenetics, with a focus on clinical translation and methodological challenges. RECENT FINDINGS:Recently, various polymorphisms associated with differential antidepressant efficacy, tolerab...
journal_title:Current opinion in psychiatry
pub_type: 杂志文章,评审
doi:10.1097/YCO.0000000000000023
更新日期:2014-01-01 00:00:00
abstract:PURPOSE OF REVIEW:This work reviews recent research regarding treatment of fragile X syndrome (FXS), the most common inherited cause of intellectual disability and autism spectrum disorder. The phenotype includes anxiety linked to sensory hyperarousal, hyperactivity, and attentional problems consistent with attention d...
journal_title:Current opinion in psychiatry
pub_type: 杂志文章,评审
doi:10.1097/YCO.0000000000000131
更新日期:2015-03-01 00:00:00
abstract:PURPOSE OF REVIEW:Depression is a complex and burdensome condition; it often leads to personal, societal and economic costs. Despite advances in treatments, its management over time remains a challenge; many treated for depression do not achieve full recovery or remain well for long. Novel ways to monitor patients are ...
journal_title:Current opinion in psychiatry
pub_type: 杂志文章,评审
doi:10.1097/YCO.0000000000000382
更新日期:2018-01-01 00:00:00
abstract:PURPOSE OF REVIEW:Economic evaluation is becoming more and more important as a means to assist policy makers in choosing the best intervention or treatment against a pervasive scarcity of resources relative to the demands. Health service provision and the practice of geriatric psychiatry are closely associated with cos...
journal_title:Current opinion in psychiatry
pub_type: 杂志文章,评审
doi:10.1097/YCO.0b013e32830f1bd5
更新日期:2008-11-01 00:00:00
abstract:PURPOSE OF REVIEW:This article reviews recent evidence and other earlier relevant articles regarding early intervention studies for children with autism spectrum disorder (ASD). RECENT FINDINGS:There is a well-established body of empirical evidence for the effectiveness of Early Intensive Behavioural Intervention (EIB...
journal_title:Current opinion in psychiatry
pub_type: 杂志文章,评审
doi:10.1097/YCO.0000000000000043
更新日期:2014-03-01 00:00:00
abstract:PURPOSE OF REVIEW:The nomenclature and classification of somatoform disorders have undergone revisions in the fifth edition of the Diagnostic and Statistical Manual (DSM 5) and the upcoming eleventh edition of the International Classification of Diseases (ICD-11). The present review describes the changes that have evol...
journal_title:Current opinion in psychiatry
pub_type: 杂志文章
doi:10.1097/YCO.0000000000000630
更新日期:2020-09-01 00:00:00
abstract:PURPOSE OF REVIEW:The purpose of this article is to review the most relevant conceptual models of borderline personality disorder (BPD), with a focus on recent developments in this area. RECENT FINDINGS:Several conceptual models have been proposed with the aim of better understanding BPD: the borderline personality or...
journal_title:Current opinion in psychiatry
pub_type: 杂志文章,评审
doi:10.1097/YCO.0000000000000374
更新日期:2018-01-01 00:00:00
abstract:PURPOSE OF REVIEW:The perinatal period introduces a myriad of changes. One important but often overlooked change is the increased risk for sleep disturbance. Although casually regarded as a consequence of pregnancy or postpartum, there is emerging evidence to suggest that women with significant sleep disturbance, chara...
journal_title:Current opinion in psychiatry
pub_type: 杂志文章,评审
doi:10.1097/YCO.0000000000000206
更新日期:2015-11-01 00:00:00
abstract:PURPOSE OF REVIEW:Psychotropic medications are commonly prescribed to people with intellectual disability. We reviewed current evidence-based pharmacotherapy options and recent updates to guide clinicians in their medication management plans. RECENT FINDINGS:Antipsychotics, particularly risperidone, appear to be effec...
journal_title:Current opinion in psychiatry
pub_type: 杂志文章,评审
doi:10.1097/YCO.0000000000000233
更新日期:2016-03-01 00:00:00
abstract:PURPOSE OF REVIEW:Cognitive dysfunction in major depressive disorder (MDD) is common, pervasive across multiple subdomains of cognitive function, and is a principle determinant of health outcomes from patient, provider, and societal perspectives. The overarching aim herein is to provide rationale for the evaluation, me...
journal_title:Current opinion in psychiatry
pub_type: 杂志文章,评审
doi:10.1097/YCO.0000000000000221
更新日期:2016-01-01 00:00:00
abstract:PURPOSE OF REVIEW:Including the psychopathic specifier within the Diagnostic and Statistical Manual of Mental Disorders Fifth Edition alternative model of personality disorder (AMPD) trait conceptualization of antisocial personality disorder (ASPD) represents a significant development in the history of the conceptualiz...
journal_title:Current opinion in psychiatry
pub_type: 杂志文章
doi:10.1097/YCO.0000000000000648
更新日期:2021-01-01 00:00:00
abstract:PURPOSE OF REVIEW:Depression is a common and disabling disorder that affects people of all ages and 10% of those older than 65 years. Current strategies to decrease the personal and societal burden of depression in older age rely on the management of people with depression or of those at risk, but benefits have been li...
journal_title:Current opinion in psychiatry
pub_type: 杂志文章,评审
doi:10.1097/YCO.0b013e328356bd57
更新日期:2012-11-01 00:00:00
abstract:PURPOSE OF REVIEW:Public health concern regarding the nonmedical use of prescription stimulants among youth has generated the need for increased understanding of diversion, which is the illegal sharing and selling of prescription drugs. Although our understanding of nonmedical use of stimulants has increased, the same ...
journal_title:Current opinion in psychiatry
pub_type: 杂志文章
doi:10.1097/YCO.0000000000000172
更新日期:2015-07-01 00:00:00
abstract:PURPOSE OF REVIEW:In recent years, deficits in emotion regulation have been studied as a putative maintaining factor and promising treatment target in a broad range of mental disorders. This article aims to provide an integrative review of the latest theoretical and empirical developments in this rapidly growing field ...
journal_title:Current opinion in psychiatry
pub_type: 杂志文章,评审
doi:10.1097/YCO.0b013e3283503669
更新日期:2012-03-01 00:00:00
abstract:PURPOSE OF REVIEW:Bariatric surgery is the most effective treatment for morbid obesity. However, 20-30% of patients undergoing bariatric surgery experience premature weight stabilization or weight regain postoperatively. We report on the recent literature of predictors of weight loss and the efficacy of cognitive behav...
journal_title:Current opinion in psychiatry
pub_type: 杂志文章,评审
doi:10.1097/YCO.0000000000000359
更新日期:2017-11-01 00:00:00
abstract:PURPOSE OF REVIEW:To review evidence on the validity and utility of recent approaches to subtyping late-life mild cognitive impairment. RECENT FINDINGS:There is growing evidence that amnestic mild cognitive impairment is associated with biomarkers for Alzheimer's disease, while nonamnestic mild cognitive impairment ma...
journal_title:Current opinion in psychiatry
pub_type: 杂志文章,评审
doi:10.1097/YCO.0b013e328344696b
更新日期:2011-05-01 00:00:00
abstract:PURPOSE OF REVIEW:To review the rationale behind and the use of cerebrospinal fluid (CSF) biomarkers in Alzheimer's disease (AD). Established as well as new candidate biomarkers will be covered. RECENT FINDINGS:AD is a complex disorder and the AD brain is characterized by multiple pathological processes, in addition t...
journal_title:Current opinion in psychiatry
pub_type: 杂志文章,评审
doi:10.1097/YCO.0b013e32835f6747
更新日期:2013-05-01 00:00:00
abstract:PURPOSE OF REVIEW:We review the recent literature on the comparative efficacy/effectiveness of antipsychotic long-acting injections (LAIs) vs. oral antipsychotics. Randomized controlled trials (RCTs), mirror-image studies and cohort studies are reviewed, and the strength and weaknesses of each design discussed. RECENT...
journal_title:Current opinion in psychiatry
pub_type: 杂志文章,评审
doi:10.1097/YCO.0000000000000160
更新日期:2015-05-01 00:00:00
abstract:PURPOSE OF REVIEW:Specific phobias are prevalent and often disabling anxiety disorders. The present review examines relevant investigations that have been published during the last 2 years on major aspects of this group of disorders. RECENT FINDINGS:Recent studies have come mainly from epidemiology, brain imagery and ...
journal_title:Current opinion in psychiatry
pub_type: 杂志文章,评审
doi:10.1097/YCO.0b013e3282f30086
更新日期:2008-01-01 00:00:00
abstract:PURPOSE OF REVIEW:The aim of this article is to critically review the current literature on treatment-refractory schizophrenia with an emphasis on emergent themes and key findings. RECENT FINDINGS:New information continues to emerge on the impact of each second-generation antipsychotic on the treatment-refractory pati...
journal_title:Current opinion in psychiatry
pub_type: 杂志文章
doi:10.1097/00001504-200503000-00010
更新日期:2005-03-01 00:00:00
abstract:PURPOSE OF REVIEW:The present review focuses on atypical antipsychotics and tardive dyskinesia. RECENT FINDINGS:We have known for many years that clozapine has a diminished risk of tardive dyskinesia compared with typical antipsychotics. The last decade has seen the introduction of a number of other atypical antipsych...
journal_title:Current opinion in psychiatry
pub_type: 杂志文章,评审
doi:10.1097/YCO.0b013e328017f6b1
更新日期:2007-03-01 00:00:00
abstract:PURPOSE OF REVIEW:The government is recognizing the need to deal with the growing numbers of antisocial young people through investing in early preventive parenting support. It is important that the services provided are evidence-based and delivered effectively. This review briefly discusses the contribution of parenti...
journal_title:Current opinion in psychiatry
pub_type: 杂志文章
doi:10.1097/01.yco.0000172056.63401.e0
更新日期:2005-07-01 00:00:00
abstract:PURPOSE OF REVIEW:This review examines progress being made in the treatment of cocaine abuse and dependence, with a particular focus on pharmacotherapies. Medications with apparently very different mechanisms of action have been reported to reduce cocaine use in controlled clinical trials in outpatient settings. This r...
journal_title:Current opinion in psychiatry
pub_type: 杂志文章
doi:10.1097/01.yco.0000165596.98552.02
更新日期:2005-05-01 00:00:00
abstract:PURPOSE OF REVIEW:To collect and update published information on the stigma associated with substance abuse in nonclinical samples, which has not been recently reviewed. RECENT FINDINGS:Searching large databases, a total of only 17 articles were published since 1999, with the majority of studies conducted outside the ...
journal_title:Current opinion in psychiatry
pub_type: 杂志文章,评审
doi:10.1097/YCO.0000000000000351
更新日期:2017-09-01 00:00:00
abstract:PURPOSE OF REVIEW:Pilowsky introduced the term 'abnormal illness behaviour' to characterize syndromes of excessive or inadequate response to symptoms, including hypochondriasis, somatization, and denial of illness. This review summarizes recent work from sociology, health psychology and psychiatry that contributes to a...
journal_title:Current opinion in psychiatry
pub_type: 杂志文章,评审
doi:10.1097/01.yco.0000194810.76096.f2
更新日期:2006-01-01 00:00:00
abstract:PURPOSE OF REVIEW:The present review compares and contrasts the diagnostic entities and taxonomy of substance use and addictive disorders in the beta draft of the Eleventh Revision of the International Classification of Diseases (ICD 11), which was released in November 2016, and the Fifth Edition of the Diagnostic and ...
journal_title:Current opinion in psychiatry
pub_type: 杂志文章,评审
doi:10.1097/YCO.0000000000000332
更新日期:2017-07-01 00:00:00
abstract:PURPOSE OF REVIEW:Extensive research exists that collaborative primary care-mental health models can improve care and outcomes for patients. These programs are currently being implemented throughout the United States and beyond. The purpose of this study is to review the literature and to generate an overview of strate...
journal_title:Current opinion in psychiatry
pub_type: 杂志文章,评审
doi:10.1097/YCO.0b013e328363a69f
更新日期:2013-09-01 00:00:00