Abstract:
PURPOSE OF REVIEW:Cognitive dysfunction in major depressive disorder (MDD) is common, pervasive across multiple subdomains of cognitive function, and is a principle determinant of health outcomes from patient, provider, and societal perspectives. The overarching aim herein is to provide rationale for the evaluation, measurement, and specific treatment of cognitive function in adults with MDD. RECENT FINDINGS:Evidence indicates that cognitive dysfunction in MDD is a critical mediator of workplace disability. Systematic evaluation and measurement of cognitive function is warranted. All individuals with MDD should be evaluated for both objective and subjective cognitive dysfunction. Although differences between antidepressants in overall antidepressant efficacy are not consistent, unequivocal differences in improving measures of cognitive function are noted with evidence indicating that vortioxetine has multidomain cognitive benefits, whereas duloxetine has replicated evidence of improving measures of acquisition and recall (i.e. memory). SUMMARY:The probability of functional recovery in MDD is likely to increase with interventions that specifically target and improve measures of cognitive function. Clinicians are encouraged to evaluate patients using a validated measure (e.g. the THINC-it tool); prevention of cognitive impairment in MDD is a critical therapeutic priority. Vortioxetine and duloxetine benefit measures of cognitive function in MDD. Preliminary evidence of beneficial effects on cognitive emotional processing are reported with ketamine.
journal_name
Curr Opin Psychiatryjournal_title
Current opinion in psychiatryauthors
McIntyre RS,Lee Ydoi
10.1097/YCO.0000000000000221subject
Has Abstractpub_date
2016-01-01 00:00:00pages
48-55issue
1eissn
0951-7367issn
1473-6578journal_volume
29pub_type
杂志文章,评审abstract:PURPOSE OF REVIEW:The development of acute and posttraumatic stress symptoms after a traumatic event is common and often leads to personal distress, functional impairment, and economic consequences in trauma victims and their loved ones. Hence, the prevention of acute and chronic posttraumatic stress is an important pu...
journal_title:Current opinion in psychiatry
pub_type: 杂志文章,评审
doi:10.1097/YCO.0b013e32834cdde2
更新日期:2011-11-01 00:00:00
abstract:PURPOSE OF REVIEW:Policies that limit young people's access to cannabis may reduce early onset of use and minimize health-related harm. This review article provides an update of recent research examining the influence of the cannabis policy frameworks on the use of cannabis by young people. RECENT FINDINGS:There are s...
journal_title:Current opinion in psychiatry
pub_type: 杂志文章,评审
doi:10.1097/YCO.0000000000000253
更新日期:2016-07-01 00:00:00
abstract:PURPOSE OF REVIEW:Recent research suggests that expectations might be a particularly important subgroup of cognitions in major depression. The present study aimed to further specify the role of situation-specific dysfunctional expectations (SDEs) in the development of depressive symptoms. It was hypothesized that the e...
journal_title:Current opinion in psychiatry
pub_type: 杂志文章
doi:10.1097/YCO.0000000000000443
更新日期:2018-09-01 00:00:00
abstract:PURPOSE OF REVIEW:Current issues in consultation-liaison psychiatry, which is now labeled psychosomatic medicine as a formal subspecialty by the American Board of Psychiatry and Neurology, are discussed. RECENT FINDINGS:There is continued interest in how to best manage depression and anxiety in a primary-care setting....
journal_title:Current opinion in psychiatry
pub_type: 杂志文章,meta分析,评审
doi:10.1097/YCO.0b013e3282f393ae
更新日期:2008-03-01 00:00:00
abstract:PURPOSE OF REVIEW:In this paper, we analyze the concept of objectivity as it is accepted in the 'standard position' on ethical practice in forensic psychiatry and confront it with the current trends of psychiatric nosology, specially the debate that we have now regarding the theoretical orientation of DSM-5, which is i...
journal_title:Current opinion in psychiatry
pub_type: 杂志文章,评审
doi:10.1097/YCO.0b013e32833cd1e6
更新日期:2010-09-01 00:00:00
abstract:PURPOSE OF REVIEW:This review examines progress being made in the treatment of cocaine abuse and dependence, with a particular focus on pharmacotherapies. Medications with apparently very different mechanisms of action have been reported to reduce cocaine use in controlled clinical trials in outpatient settings. This r...
journal_title:Current opinion in psychiatry
pub_type: 杂志文章
doi:10.1097/01.yco.0000165596.98552.02
更新日期:2005-05-01 00:00:00
abstract:PURPOSE OF REVIEW:This review explores recent literature on the applicability of the Diagnostic and Statistical Manual of Mental Disorders, 5th Edition (DSM-5) and International Classification of Disease, 11th Revision (ICD-11) personality disorder classification systems across countries and cultural contexts. RECENT ...
journal_title:Current opinion in psychiatry
pub_type: 杂志文章
doi:10.1097/YCO.0000000000000659
更新日期:2021-01-01 00:00:00
abstract:PURPOSE OF REVIEW:The current review aims to describe and evaluate research on cognitive difficulties associated with posttraumatic stress disorder (PTSD) published between January 2007 and June 2008. RECENT FINDINGS:The reviewed studies provide additional evidence that negative appraisals and decrements on verbal and...
journal_title:Current opinion in psychiatry
pub_type: 杂志文章,评审
doi:10.1097/YCO.0b013e328314e3bb
更新日期:2009-01-01 00:00:00
abstract:PURPOSE OF REVIEW:This review highlights the epidemiologic research on club drug use in the past year, with a focus on clinical epidemiology, social epidemiology, new methodological approaches, and alternative explanations for drug use behaviors. RECENT FINDINGS:Although 3,4-methylenedioxy-N-methylamphetamine (MDMA) o...
journal_title:Current opinion in psychiatry
pub_type: 杂志文章,多中心研究,评审
doi:10.1097/YCO.0b013e3282f9b1f1
更新日期:2008-05-01 00:00:00
abstract:PURPOSE OF REVIEW:Health disparities are evident between people with intellectual disabilities and the general population. Despite the potential of indicators for measuring disparities and planning interventions to address inequalities- currently a priority health policy target- few studies have mapped the physical or ...
journal_title:Current opinion in psychiatry
pub_type: 杂志文章,评审
doi:10.1097/YCO.0b013e3283065bc6
更新日期:2008-09-01 00:00:00
abstract:PURPOSE OF REVIEW:Abuse of new psychoactive substances (NPS) has been a new global concern. So far, there has been no international consensus on legislative control of NPS. Scrutiny of Taiwan's illegal drug use history reveals that legislation and policy play an important role in tackling the drug issues. RECENT FINDI...
journal_title:Current opinion in psychiatry
pub_type: 杂志文章
doi:10.1097/YCO.0000000000000604
更新日期:2020-07-01 00:00:00
abstract:PURPOSE OF REVIEW:Alcohol is widely available and one of the most commonly used psychoactive substances. This review examined the recent literature for empirical research addressing the cause, prevalence and treatment of alcohol-related problems in adolescents and adults with intellectual disabilities. RECENT FINDINGS...
journal_title:Current opinion in psychiatry
pub_type: 杂志文章,评审
doi:10.1097/01.yco.0000238474.07078.41
更新日期:2006-09-01 00:00:00
abstract:PURPOSE OF REVIEW:Considerable progress has been made in the neurobiological understanding of expectations in physiological and pathological processes. This article is aimed at presenting an overview of the role of expectations in producing health-related effects. We selected recent laboratory and clinical studies in t...
journal_title:Current opinion in psychiatry
pub_type: 杂志文章,评审
doi:10.1097/YCO.0b013e328343803b
更新日期:2011-03-01 00:00:00
abstract:PURPOSE OF REVIEW:We reviewed the recent literature on prevalence rates, and application of evidence-based treatments for eating disorders among Hispanics/Latinos residing in the United States. RECENT FINDINGS:Lifetime prevalence rates of anorexia nervosa are lower among Hispanic/Latinos than non-Hispanic Whites. Ther...
journal_title:Current opinion in psychiatry
pub_type: 杂志文章,评审
doi:10.1097/YCO.0000000000000277
更新日期:2016-11-01 00:00:00
abstract:PURPOSE OF REVIEW:Social cognition training is an emerging intervention, which aims to ameliorate impairment in social interaction and improve functional outcomes in persons with a psychosis. This article reviews the research conducted on the impact of this intervention published in English language journals over the p...
journal_title:Current opinion in psychiatry
pub_type: 杂志文章,评审
doi:10.1097/YCO.0b013e3283642cf1
更新日期:2013-09-01 00:00:00
abstract:PURPOSE OF REVIEW:Schizophrenia occurs in ∼25% of individuals with 22q11.2 deletion syndrome (22q11.2DS), the strongest known molecular genetic risk factor for schizophrenia. This review highlights recent literature in 22q11.2DS as it pertains to psychosis and schizophrenia. RECENT FINDINGS:Advances in noninvasive pre...
journal_title:Current opinion in psychiatry
pub_type: 杂志文章,评审
doi:10.1097/YCO.0000000000000324
更新日期:2017-05-01 00:00:00
abstract:PURPOSE OF REVIEW:The aim of this article is to investigate psychopathology in order to illuminate the nature of personal identity. RECENT FINDINGS:Predominantly, the authors reviewed here defend a more robust version of the narrative self against Dennett's claim that narrative self is ultimately a useful fiction. Aut...
journal_title:Current opinion in psychiatry
pub_type: 杂志文章
doi:10.1097/01.yco.0000184415.44329.11
更新日期:2005-11-01 00:00:00
abstract:PURPOSE OF REVIEW:To raise awareness of and inform evidence-based practice regarding medical and behavioral interventions for antipsychotic medication-induced metabolic abnormalities. RECENT FINDINGS:The current literature indicates that individuals with severe and persistent mental illness have significantly worse he...
journal_title:Current opinion in psychiatry
pub_type: 杂志文章,评审
doi:10.1097/YCO.0b013e328314b74b
更新日期:2008-11-01 00:00:00
abstract:PURPOSE OF REVIEW:Social cognition refers broadly to the way in which we process social information, and is a critical predictor of social competency. This article provides an overview of some of the assessment approaches that have been developed to assess this construct. RECENT FINDINGS:A variety of well validated as...
journal_title:Current opinion in psychiatry
pub_type: 杂志文章,评审
doi:10.1097/YCO.0000000000000139
更新日期:2015-03-01 00:00:00
abstract:PURPOSE OF REVIEW:The importance of ensuring robust arrangements for young people's transitions from specialist child and adolescent mental health services to specialist mental health services for adults is well documented in the international literature. Nonetheless, according to young people, there remains great vari...
journal_title:Current opinion in psychiatry
pub_type: 杂志文章,评审
doi:10.1097/YCO.0b013e32833a51e2
更新日期:2010-07-01 00:00:00
abstract:PURPOSE OF REVIEW:Inpatient services constitute the most highly specialized child and adolescent mental health provision and cater for the most severe disorders in this age group. In view of a number of mapping and audit initiatives in the UK in recent years and changing influences on admission policies worldwide, it i...
journal_title:Current opinion in psychiatry
pub_type: 杂志文章
doi:10.1097/01.yco.0000172066.24391.be
更新日期:2005-07-01 00:00:00
abstract:PURPOSE OF REVIEW:The aim of this review is to describe the considerable advances in consolidating the empirical evidence on several key topics in the genetics of attention deficit hyperactivity disorder, namely the quantitative genetic studies of the nature of attention deficit hyperactivity disorder and its comorbidi...
journal_title:Current opinion in psychiatry
pub_type: 杂志文章,评审
doi:10.1097/YCO.0b013e328303ba54
更新日期:2008-07-01 00:00:00
abstract:PURPOSE OF REVIEW:Schizophrenia (SCZ) and bipolar disorder are severe mental disorders, both placing a significant burden on individuals' wellbeing and global health generally. The complex interaction of multiple mechanisms, underlying these disorders, still needs further elucidation. Increased activation of components...
journal_title:Current opinion in psychiatry
pub_type: 杂志文章,评审
doi:10.1097/YCO.0000000000000499
更新日期:2019-05-01 00:00:00
abstract:PURPOSE OF REVIEW:With increasing awareness of potential differences of autism presentation in nonmale versus male individuals, this review summarizes the rapidly evolving literature on sex and gender impacts on autism across nosology, behavioural presentation, developmental change and contextual recognition biases. R...
journal_title:Current opinion in psychiatry
pub_type: 杂志文章,评审
doi:10.1097/YCO.0000000000000575
更新日期:2020-03-01 00:00:00
abstract:PURPOSE OF REVIEW:Depression is a complex and burdensome condition; it often leads to personal, societal and economic costs. Despite advances in treatments, its management over time remains a challenge; many treated for depression do not achieve full recovery or remain well for long. Novel ways to monitor patients are ...
journal_title:Current opinion in psychiatry
pub_type: 杂志文章,评审
doi:10.1097/YCO.0000000000000382
更新日期:2018-01-01 00:00:00
abstract:PURPOSE OF REVIEW:To provide an update of the recent studies on the olfactory function in Alzheimer's disease, with a focus on the olfactory identification function. RECENT FINDINGS:The studies reviewed here confirm previous reports on the poor olfactory function in Alzheimer's disease compared to health normal contro...
journal_title:Current opinion in psychiatry
pub_type: 杂志文章,评审
doi:10.1097/YCO.0000000000000146
更新日期:2015-03-01 00:00:00
abstract:PURPOSE OF REVIEW:Compelling evidence suggests that a small group of men who develop schizophrenia display a stable pattern of antisocial behaviour from childhood onwards, causing considerable suffering to victims and to themselves and imposing a significant financial burden on society. We reviewed the literature on th...
journal_title:Current opinion in psychiatry
pub_type: 杂志文章,评审
doi:10.1097/01.yco.0000238484.12023.aa
更新日期:2006-09-01 00:00:00
abstract:PURPOSE OF REVIEW:Clinical practice guidelines (CPGs) do not usually offer a sex-specific approach for the management of schizophrenia. With this narrative review, we aim to give an integrated and synthesized overview of the current state of knowledge regarding sex-specific aspects in schizophrenia and how this topic m...
journal_title:Current opinion in psychiatry
pub_type: 杂志文章
doi:10.1097/YCO.0000000000000597
更新日期:2020-05-01 00:00:00
abstract:PURPOSE OF REVIEW:Screening measures for bipolar disorder are positioned as playing an important role in improving diagnostic accuracy. This review considers the principal screening measures developed over the past decade. RECENT FINDINGS:Although the development and evaluation of bipolar screening measures were disti...
journal_title:Current opinion in psychiatry
pub_type: 杂志文章,评审
doi:10.1097/YCO.0000000000000125
更新日期:2015-01-01 00:00:00
abstract:PURPOSE OF REVIEW:To increase the expert knowledge-base on intellectual developmental disorders (IDDs) by investigating the typology trajectories of consensus formation in the classification systems up to the 11th edition of the International Classification of Diseases (ICD-11). This expert review combines an analysis ...
journal_title:Current opinion in psychiatry
pub_type: 杂志文章,评审
doi:10.1097/YCO.0000000000000396
更新日期:2018-03-01 00:00:00