Should mild cognitive impairment be subtyped?

Abstract:

PURPOSE OF REVIEW:To review evidence on the validity and utility of recent approaches to subtyping late-life mild cognitive impairment. RECENT FINDINGS:There is growing evidence that amnestic mild cognitive impairment is associated with biomarkers for Alzheimer's disease, while nonamnestic mild cognitive impairment maps more closely to cerebrovascular disease. The former is more likely to progress to dementia than the latter. Mild impairment in multiple cognitive domains appears to represent a more advanced disease state than single-domain impairment, and is more likely to progress to dementia. The cognitive subtypes have imprecise boundaries and have limited ecological validity. Approaches to subtyping that also incorporate biomarkers increase diagnostic specificity and have greater predictive value. However, these approaches have yet to be validated outside specialized memory clinic populations. SUMMARY:Mild cognitive impairment as currently defined is still etiologically and prognostically heterogeneous, particularly outside specialty clinical settings. The objective of further subtyping is to delineate subgroups that are more clinically homogeneous. The current cognitive subtypes have some validity and utility but additional approaches should be explored so as to enhance these properties.

journal_name

Curr Opin Psychiatry

authors

Hughes TF,Snitz BE,Ganguli M

doi

10.1097/YCO.0b013e328344696b

subject

Has Abstract

pub_date

2011-05-01 00:00:00

pages

237-42

issue

3

eissn

0951-7367

issn

1473-6578

journal_volume

24

pub_type

杂志文章,评审
  • Alcohol-related problems in adolescents and adults with intellectual disabilities.

    abstract:PURPOSE OF REVIEW:Alcohol is widely available and one of the most commonly used psychoactive substances. This review examined the recent literature for empirical research addressing the cause, prevalence and treatment of alcohol-related problems in adolescents and adults with intellectual disabilities. RECENT FINDINGS...

    journal_title:Current opinion in psychiatry

    pub_type: 杂志文章,评审

    doi:10.1097/01.yco.0000238474.07078.41

    authors: Barrett N,Paschos D

    更新日期:2006-09-01 00:00:00

  • How does level of personality functioning inform clinical management and treatment? Implications for ICD-11 classification of personality disorder severity.

    abstract:PURPOSE OF REVIEW:The International Classification of Diseases, 11th Edition (ICD-11) classifies personality disturbance according to levels of severity. This article reviews the literature on levels of personality functioning in relation to clinical management and treatment, and proposes how these findings apply to th...

    journal_title:Current opinion in psychiatry

    pub_type: 杂志文章

    doi:10.1097/YCO.0000000000000658

    authors: Bach B,Simonsen S

    更新日期:2021-01-01 00:00:00

  • Antecedents, consequences and interventions for workplace bullying.

    abstract:PURPOSE OF REVIEW:The issue of workplace bullying has become an area of research interest in the last 3 decades. Much of the extant literature is published in the business management journals. This is problematic as the targets of workplace bullying may need psychiatric treatment; as a discipline, therefore psychiatris...

    journal_title:Current opinion in psychiatry

    pub_type: 杂志文章,评审

    doi:10.1097/YCO.0000000000000084

    authors: Kemp V

    更新日期:2014-09-01 00:00:00

  • Pharmacotherapy for mental health problems in people with intellectual disability.

    abstract:PURPOSE OF REVIEW:Psychotropic medications are commonly prescribed to people with intellectual disability. We reviewed current evidence-based pharmacotherapy options and recent updates to guide clinicians in their medication management plans. RECENT FINDINGS:Antipsychotics, particularly risperidone, appear to be effec...

    journal_title:Current opinion in psychiatry

    pub_type: 杂志文章,评审

    doi:10.1097/YCO.0000000000000233

    authors: Ji NY,Findling RL

    更新日期:2016-03-01 00:00:00

  • Service provision for mentally disordered homeless people.

    abstract:PURPOSE OF REVIEW:Mentally ill homeless persons are among the most neglected or marginalized patient groups. Their needs for mental healthcare are widely unmet. The current economic crisis probably accelerates the social decline and deterioration of physical and mental health in high-risk groups worldwide and increases...

    journal_title:Current opinion in psychiatry

    pub_type: 杂志文章,评审

    doi:10.1097/YCO.0b013e328361e596

    authors: Salize HJ,Werner A,Jacke CO

    更新日期:2013-07-01 00:00:00

  • Magnitude and impact of comorbidity of mental disorders from epidemiologic surveys.

    abstract:PURPOSE OF REVIEW:To consider comorbidity across multiple classes of disorders in data derived from recent large-scale community surveys. RECENT FINDINGS:There has been substantial recent progress in our understanding of patterns and implications of comorbidity of mental disorders. There is now converging evidence on ...

    journal_title:Current opinion in psychiatry

    pub_type: 杂志文章,评审

    doi:10.1097/YCO.0b013e3281c61dc5

    authors: Merikangas KR,Kalaydjian A

    更新日期:2007-07-01 00:00:00

  • Models of borderline personality disorder: recent advances and new perspectives.

    abstract:PURPOSE OF REVIEW:The purpose of this article is to review the most relevant conceptual models of borderline personality disorder (BPD), with a focus on recent developments in this area. RECENT FINDINGS:Several conceptual models have been proposed with the aim of better understanding BPD: the borderline personality or...

    journal_title:Current opinion in psychiatry

    pub_type: 杂志文章,评审

    doi:10.1097/YCO.0000000000000374

    authors: D'Agostino A,Rossi Monti M,Starcevic V

    更新日期:2018-01-01 00:00:00

  • Treatment of the psychiatric problems associated with fragile X syndrome.

    abstract:PURPOSE OF REVIEW:This work reviews recent research regarding treatment of fragile X syndrome (FXS), the most common inherited cause of intellectual disability and autism spectrum disorder. The phenotype includes anxiety linked to sensory hyperarousal, hyperactivity, and attentional problems consistent with attention d...

    journal_title:Current opinion in psychiatry

    pub_type: 杂志文章,评审

    doi:10.1097/YCO.0000000000000131

    authors: Hagerman RJ,Polussa J

    更新日期:2015-03-01 00:00:00

  • The importance of faith-based mental healthcare in African urbanized sites.

    abstract:PURPOSE OF REVIEW:This review highlights what current research says about how local beliefs and norms can facilitate expansion of mental healthcare to meet the large unmet need for services in Africa. RECENT FINDINGS:In contemporary Africa, religious beliefs exert important influences on mental health as well as the w...

    journal_title:Current opinion in psychiatry

    pub_type: 杂志文章

    doi:10.1097/YCO.0000000000000590

    authors: Ojagbemi A,Gureje O

    更新日期:2020-05-01 00:00:00

  • Situational expectations mediate the effect of global beliefs on depressive symptoms: a 1-year prospective study using a student sample.

    abstract:PURPOSE OF REVIEW:Recent research suggests that expectations might be a particularly important subgroup of cognitions in major depression. The present study aimed to further specify the role of situation-specific dysfunctional expectations (SDEs) in the development of depressive symptoms. It was hypothesized that the e...

    journal_title:Current opinion in psychiatry

    pub_type: 杂志文章

    doi:10.1097/YCO.0000000000000443

    authors: Kube T,Glombiewski JA,Rief W

    更新日期:2018-09-01 00:00:00

  • The role of religion and spirituality in mental health.

    abstract:PURPOSE OF REVIEW:There has been increased interest in the relationship between religion and spirituality and mental health in recent years. This article reviews recent research into the capacity of religion and spirituality to benefit or harm the mental health of believers. We also examine the implications this may ha...

    journal_title:Current opinion in psychiatry

    pub_type: 杂志文章,评审

    doi:10.1097/YCO.0000000000000080

    authors: Weber SR,Pargament KI

    更新日期:2014-09-01 00:00:00

  • Implementation strategies for collaborative primary care-mental health models.

    abstract:PURPOSE OF REVIEW:Extensive research exists that collaborative primary care-mental health models can improve care and outcomes for patients. These programs are currently being implemented throughout the United States and beyond. The purpose of this study is to review the literature and to generate an overview of strate...

    journal_title:Current opinion in psychiatry

    pub_type: 杂志文章,评审

    doi:10.1097/YCO.0b013e328363a69f

    authors: Franx G,Dixon L,Wensing M,Pincus H

    更新日期:2013-09-01 00:00:00

  • Tardive dyskinesia: eliminated, forgotten, or overshadowed?

    abstract:PURPOSE OF REVIEW:The present review focuses on atypical antipsychotics and tardive dyskinesia. RECENT FINDINGS:We have known for many years that clozapine has a diminished risk of tardive dyskinesia compared with typical antipsychotics. The last decade has seen the introduction of a number of other atypical antipsych...

    journal_title:Current opinion in psychiatry

    pub_type: 杂志文章,评审

    doi:10.1097/YCO.0b013e328017f6b1

    authors: Remington G

    更新日期:2007-03-01 00:00:00

  • Prevention of common mental disorders: conceptual framework and effective interventions.

    abstract:PURPOSE OF REVIEW:Mental disorders take a major toll, economically, socially, and psychologically, on individuals, families, and societies. Prevention provides an important and realistic opportunity to overcome this major health problem. This review outlines a conceptual framework for mental health prevention and effec...

    journal_title:Current opinion in psychiatry

    pub_type: 杂志文章,评审

    doi:10.1097/YCO.0000000000000076

    authors: D'Arcy C,Meng X

    更新日期:2014-07-01 00:00:00

  • Measuring psychosocial outcome is good.

    abstract:PURPOSE OF REVIEW:Poor psychosocial functioning in schizophrenia can be conceptualized as an early indicator of chronic neurodevelopmental illness. Alternatively, impaired psychosocial functioning could be the result of social and environmental factors associated with the onset of psychotic illness. We review recent ev...

    journal_title:Current opinion in psychiatry

    pub_type: 杂志文章,评审

    doi:10.1097/YCO.0b013e32835d82aa

    authors: Lin A,Wood SJ,Yung AR

    更新日期:2013-03-01 00:00:00

  • The many ages of man: diverse approaches to assessing ageing-related biological and psychological measures and their relationship to chronological age.

    abstract:PURPOSE OF REVIEW:Chronological age is a crude measure and may not be the best indicator of the ageing process. Establishing valid and reliable biomarkers to understand the true effect of ageing is of great interest. We provide an overview of biological and psychological characteristics that change with age and can pot...

    journal_title:Current opinion in psychiatry

    pub_type: 杂志文章,评审

    doi:10.1097/YCO.0000000000000473

    authors: Foo H,Mather KA,Thalamuthu A,Sachdev PS

    更新日期:2019-03-01 00:00:00

  • Immediate and early behavioral interventions for the prevention of acute and posttraumatic stress disorder.

    abstract:PURPOSE OF REVIEW:The development of acute and posttraumatic stress symptoms after a traumatic event is common and often leads to personal distress, functional impairment, and economic consequences in trauma victims and their loved ones. Hence, the prevention of acute and chronic posttraumatic stress is an important pu...

    journal_title:Current opinion in psychiatry

    pub_type: 杂志文章,评审

    doi:10.1097/YCO.0b013e32834cdde2

    authors: Agorastos A,Marmar CR,Otte C

    更新日期:2011-11-01 00:00:00

  • Why do patients with schizophrenia smoke?

    abstract:PURPOSE OF REVIEW:Among the mentally ill, smoking prevalence is highest in patients with schizophrenia ( approximately 70-80%). This can impose a significant financial burden on patients, not to speak of increased smoking-related morbidity and mortality. Therefore, it is critical for clinicians to understand why patien...

    journal_title:Current opinion in psychiatry

    pub_type: 杂志文章,评审

    doi:10.1097/YCO.0b013e3283366643

    authors: Winterer G

    更新日期:2010-03-01 00:00:00

  • Comorbidity of psychiatric and substance use disorders in the United States: current issues and findings from the NESARC.

    abstract:PURPOSE OF REVIEW:The comorbidity between psychiatric and substance use disorders remains an important phenomenon to understand, and an active area of investigation. The purpose of this review is to highlight key 2011 issues and novel findings on psychiatric and substance disorders comorbidity from the National Epidemi...

    journal_title:Current opinion in psychiatry

    pub_type: 杂志文章,评审

    doi:10.1097/YCO.0b013e3283523dcc

    authors: Hasin D,Kilcoyne B

    更新日期:2012-05-01 00:00:00

  • Recent trends in behavioral medicine.

    abstract:PURPOSE OF REVIEW:Behavioral medicine is an interdisciplinary field, integrating research from a variety of disciplines. This review focuses on recent advances and developments in behavioral medicine. RECENT FINDINGS:Stress, as well as having a role in the etiology and maintenance of somatic disease and somatoform dis...

    journal_title:Current opinion in psychiatry

    pub_type: 杂志文章,评审

    doi:10.1097/01.yco.0000214345.37002.77

    authors: Nater UM,Gaab J,Rief W,Ehlert U

    更新日期:2006-03-01 00:00:00

  • Cerebrospinal fluid biomarkers for pathological processes in Alzheimer's disease.

    abstract:PURPOSE OF REVIEW:To review the rationale behind and the use of cerebrospinal fluid (CSF) biomarkers in Alzheimer's disease (AD). Established as well as new candidate biomarkers will be covered. RECENT FINDINGS:AD is a complex disorder and the AD brain is characterized by multiple pathological processes, in addition t...

    journal_title:Current opinion in psychiatry

    pub_type: 杂志文章,评审

    doi:10.1097/YCO.0b013e32835f6747

    authors: Rosén C,Zetterberg H

    更新日期:2013-05-01 00:00:00

  • Substance use and addictive disorders in DSM-5 and ICD 10 and the draft ICD 11.

    abstract:PURPOSE OF REVIEW:The present review compares and contrasts the diagnostic entities and taxonomy of substance use and addictive disorders in the beta draft of the Eleventh Revision of the International Classification of Diseases (ICD 11), which was released in November 2016, and the Fifth Edition of the Diagnostic and ...

    journal_title:Current opinion in psychiatry

    pub_type: 杂志文章,评审

    doi:10.1097/YCO.0000000000000332

    authors: Saunders JB

    更新日期:2017-07-01 00:00:00

  • Is it possible to carry out high-quality epidemiological research in psychiatry with limited resources?

    abstract:PURPOSE OF REVIEW:This review covers the epidemiological research from developing countries to identify the scope of research in the various aspects of epidemiology and the strengths of research. The period covered is June 2004 to June 2005. The literature survey used searches of Medline, key psychiatric journals and p...

    journal_title:Current opinion in psychiatry

    pub_type: 杂志文章

    doi:10.1097/01.yco.0000179499.23311.f3

    authors: Murthy RS,Lakshminarayana R

    更新日期:2005-09-01 00:00:00

  • Sexuality in menopausal women.

    abstract:PURPOSE OF REVIEW:Sexuality is an essential part of a healthy life. It can contribute significantly to the physical, psychological and social wellbeing of menopausal women, therefore, to their quality of life. This study is an overview of the most recent findings in the literature retrieved from searches of computerize...

    journal_title:Current opinion in psychiatry

    pub_type: 杂志文章,评审

    doi:10.1097/YCO.0000000000000280

    authors: Caruso S,Rapisarda AM,Cianci S

    更新日期:2016-11-01 00:00:00

  • Current use of benzodiazepines in anxiety disorders.

    abstract:PURPOSE OF REVIEW:The aim of this study is to provide a review of articles published between July 2007 and August 2008 on the current use and rationale of benzodiazepines in anxiety disorders. RECENT FINDINGS:Recent review articles confirm selective serotonin reuptake inhibitors as first-choice drugs for treating anxi...

    journal_title:Current opinion in psychiatry

    pub_type: 杂志文章,评审

    doi:10.1097/YCO.0b013e32831a473d

    authors: Cloos JM,Ferreira V

    更新日期:2009-01-01 00:00:00

  • Recent trends in the study of specific phobias.

    abstract:PURPOSE OF REVIEW:Specific phobias are prevalent and often disabling anxiety disorders. The present review examines relevant investigations that have been published during the last 2 years on major aspects of this group of disorders. RECENT FINDINGS:Recent studies have come mainly from epidemiology, brain imagery and ...

    journal_title:Current opinion in psychiatry

    pub_type: 杂志文章,评审

    doi:10.1097/YCO.0b013e3282f30086

    authors: Pull CB

    更新日期:2008-01-01 00:00:00

  • Cross-cultural applicability of ICD-11 and DSM-5 personality disorder.

    abstract:PURPOSE OF REVIEW:This review explores recent literature on the applicability of the Diagnostic and Statistical Manual of Mental Disorders, 5th Edition (DSM-5) and International Classification of Disease, 11th Revision (ICD-11) personality disorder classification systems across countries and cultural contexts. RECENT ...

    journal_title:Current opinion in psychiatry

    pub_type: 杂志文章

    doi:10.1097/YCO.0000000000000659

    authors: Ayinde OO,Gureje O

    更新日期:2021-01-01 00:00:00

  • The epidemiology and characteristics of stalking.

    abstract:PURPOSE OF REVIEW:This article summarizes major results in the field of epidemiology and characteristics of stalking, as published in literature between 2003 and October 2005. RECENT FINDINGS:Although stalking had been only recently conceptualized, it soon became evident that it represents a significant social and med...

    journal_title:Current opinion in psychiatry

    pub_type: 杂志文章,评审

    doi:10.1097/01.yco.0000228760.95237.f5

    authors: Dressing H,Kuehner C,Gass P

    更新日期:2006-07-01 00:00:00

  • Smoking in schizophrenia: recent findings about an old problem.

    abstract:PURPOSE OF REVIEW:Recent epidemiology, biological and clinical findings correlate high cigarette consumption in patients with schizophrenia, impeding both treatment strategies and the effectiveness of antipsychotics. RECENT FINDINGS:New data suggests that despite world-wide efforts to curb cigarette consumption, smoki...

    journal_title:Current opinion in psychiatry

    pub_type: 杂志文章,评审

    doi:10.1097/YCO.0000000000000529

    authors: Sagud M,Mihaljevic Peles A,Pivac N

    更新日期:2019-09-01 00:00:00

  • Decriminalization of drug use.

    abstract:PURPOSE OF REVIEW:To review the literature on decriminalization of drug use from 2016 to 2017 and suggest the way forward. RECENT FINDINGS:The systematic review of the literature on decriminalization resulted in seven articles that discuss decriminalization as compared with 57 published articles on legalization. Decri...

    journal_title:Current opinion in psychiatry

    pub_type: 杂志文章

    doi:10.1097/YCO.0000000000000429

    authors: Vicknasingam B,Narayanan S,Singh D,Chawarski M

    更新日期:2018-07-01 00:00:00