Abstract:
:The aim of this study was to assess the added diagnostic value of contrast-enhanced US (CEUS) combined with 64-row multidetector CT (CT) in the assessment of hepatocellular nodule vascularity in patients with liver cirrhosis. One hundred and six cirrhotic patients (68 male, 38 female; mean age +/- SD, 70 +/- 7 years) with 121 biopsy-proven hepatocellular nodules (72 hepatocellular carcinomas, 10 dysplastic and 15 regenerative nodules, 12 hemangiomas, and 12 other benignancies) detected during US surveillance were prospectively recruited. Each nodule was scanned by CEUS during the arterial (10-40 s), portal venous (45-90 s), and delayed sinusoidal phase (from 100 s after microbubble injection to microbubble disappearance). Nodule vascularity at CEUS, CT, and combined CEUS/CT was evaluated side-by-side by two independent blinded readers who classified nodules as benign or malignant according to reference diagnostic criteria. The combined assessment of CEUS/CT provided higher sensitivity (97%, both readers) than did separate assessment of CEUS (88% reader 1; 87% reader 2) and CT (74% reader 1; 71% reader 2; P < 0.05), while no change in specificity was provided by combined analysis. The combined assessment of hepatocellular nodule vascularity at CT and CEUS improved sensitivity in the diagnosis of malignancy in patients with liver cirrhosis.
journal_name
Eur Radioljournal_title
European radiologyauthors
Quaia E,Alaimo V,Baratella E,Medeot A,Midiri M,Cova MAdoi
10.1007/s00330-008-1179-3subject
Has Abstractpub_date
2009-03-01 00:00:00pages
651-63issue
3eissn
0938-7994issn
1432-1084journal_volume
19pub_type
杂志文章abstract:OBJECTIVES:To develop a non-invasive MRI method for evaluation of liver fibrosis, with histological analysis as the reference standard. METHODS:The study protocol was approved by the Institutional Review Board for Human Studies of our hospital, and written informed consent was obtained from all subjects. Seventy-nine ...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-011-2249-5
更新日期:2012-01-01 00:00:00
abstract:OBJECTIVES:To describe the MR imaging findings in adults presenting with anal incontinence following pull-through perineoplasty for anorectal atresia. METHODS:15 adults (12 male, 3 female; age 22-52 years) with anal incontinence following a prior perineal pull-through procedure as an infant for anorectal atresia were ...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-013-2949-0
更新日期:2013-12-01 00:00:00
abstract::Though recent research into the diagnosis and management of hamstring disorders has resulted in early and accurate recognition of injury, hamstring strain remains the most common form of muscle injury in the active population. With prompt recognition of hamstring strain, an appropriate rest and rehabilitation routine ...
journal_title:European radiology
pub_type: 杂志文章,评审
doi:10.1007/s00330-005-0075-3
更新日期:2006-07-01 00:00:00
abstract:OBJECTIVES:Investigate the effect of a novel Bayesian penalised likelihood (BPL) reconstruction algorithm on analysis of pulmonary nodules examined with 18F-FDG PET/CT, and to determine its effect on small, sub-10-mm nodules. METHODS:18F-FDG PET/CTs performed for nodule evaluation in 104 patients (121 nodules) were re...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-015-3832-y
更新日期:2016-02-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to test the feasibility of time-resolved computed tomography angiography (TR-CTA) for use in the lower leg. METHODS:Fifty-nine patients with suspected peripheral arterial occlusive disease were examined with a standard CTA (S-CTA) of the lower run-off and with an additional TR-CTA o...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-010-1861-0
更新日期:2010-12-01 00:00:00
abstract::Bronchioloalveolar carcinoma (BAC) is a polymorphic lung cancer the incidence of which is rising. The presence of intratumoral radiolucencies is an important feature of bronchioloalveolar carcinoma. The aim of this study was to present pictorially the spectrum of intratumoral radiolucencies visible in BAC. In 57 BACs ...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s003300050627
更新日期:1999-01-01 00:00:00
abstract:OBJECTIVES:To assess whether, in patients with normal liver function, a hepatobiliary delay time of 10 min after Gd-EOB-DTPA injection is sufficient for lesion characterisation. METHODS:In 42 consecutive patients with suspected focal liver lesions, dynamic MRI was performed after intravenous Gd-EOB-DTPA, followed by h...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-012-2486-2
更新日期:2012-10-01 00:00:00
abstract:OBJECTIVES:To evaluate the association between tumour FDG uptake on preoperative PET/CT and axillary lymph node metastasis (ALNM) according to breast cancer subtype. METHODS:The records of 671 patients with invasive breast cancer who underwent (18) F-FDG PET/CT and surgery were reviewed. Using immunohistochemistry, tu...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-014-3452-y
更新日期:2015-04-01 00:00:00
abstract:OBJECTIVES:To explain the technical principles of and differences between commercially available iterative reconstruction (IR) algorithms for computed tomography (CT) in non-mathematical terms for radiologists and clinicians. METHODS:Technical details of the different proprietary IR techniques were distilled from avai...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-012-2765-y
更新日期:2013-06-01 00:00:00
abstract:OBJECTIVES:To assess the interchangeability of zone-specific (peripheral-zone (PZ) and transition-zone (TZ)) multiparametric-MRI (mp-MRI) logistic-regression (LR) models for classification of prostate cancer. METHODS:Two hundred and thirty-one patients (70 TZ training-cohort; 76 PZ training-cohort; 85 TZ temporal vali...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-015-3636-0
更新日期:2015-09-01 00:00:00
abstract::Nonvariceal upper gastrointestinal bleeding (NUGB) remains a major medical problem even after advances in medical therapy with gastric acid suppression and cyclooxygenase (COX-2) inhibitors. Although the incidence of upper gastrointestinal bleeding presenting to the emergency room has slightly decreased, similar decre...
journal_title:European radiology
pub_type: 杂志文章,评审
doi:10.1007/s00330-006-0477-x
更新日期:2007-07-01 00:00:00
abstract::Magnetic resonance angiography (MRA) has become an imaging modality which comprises various techniques based on two concepts: methods relying on the natural flow effects, the time-of-flight and phase-contrast technique, either in two- or three-dimensional acquisition mode, and the more recently developed contrast-enha...
journal_title:European radiology
pub_type: 杂志文章,评审
doi:10.1007/s003300050834
更新日期:1999-01-01 00:00:00
abstract::Two cases of agenesis of the horizontal segment of the left portal vein are reported. This very rare vascular anomaly probably corresponds to an embryological variation rather than to an obstruction of the left portal vein. In almost all cases liver ultrasonography is sufficient for identifying such vascular abnormali...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s003300050057
更新日期:2000-01-01 00:00:00
abstract::The purpose of the study was to evaluate the CT abnormalities of airways and lung parenchyma in asthmatic patients and to assess inter- and intraobserver variability for these abnormalities. The CT scans of 50 asthmatic patients and 10 healthy volunteers were assessed independently by four independent chest radiologis...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/BF00181147
更新日期:1996-01-01 00:00:00
abstract:OBJECTIVES:To investigate whether contralateral parenchymal enhancement (CPE) on MRI during neoadjuvant endocrine therapy (NET) is associated with the preoperative endocrine prognostic index (PEPI) of ER+/HER2- breast cancer. METHODS:This retrospective observational cohort study included 40 unilateral ER+/HER2- breast...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-020-07058-3
更新日期:2020-12-01 00:00:00
abstract::The aim of this study was to analyze pulmonary embolism (PE) occurrence and retrospective clinical outcome in patients with clinically suspected acute PE and a negative spiral CT angiography (SCTA) of the pulmonary arteries. Within a 35-month period, 485 consecutive patients with clinical symptoms of acute PE underwen...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-003-2016-3
更新日期:2004-01-01 00:00:00
abstract:OBJECTIVES:To investigate the association of contrast-enhanced cone beam breast CT (CE-CBBCT) features, immunohistochemical (IHC) receptors, and molecular subtypes in breast cancer. METHODS:In this retrospective study, patients who underwent preoperative CE-CBBCT and received complete IHC results were analyzed. CE-CBB...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-020-07277-8
更新日期:2020-10-02 00:00:00
abstract::This study was prospectively conducted to evaluate the clinical potential of the advanced breast biopsy instrumentation (ABBI) system as an alternative to needle localization and open surgery in the management of nonpalpable breast lesions (NPBL). One hundred and eighty-six consecutive patients were referred for manag...
journal_title:European radiology
pub_type: 临床试验,杂志文章
doi:10.1007/s003300000736
更新日期:2001-01-01 00:00:00
abstract::The purpose of this study was to compare LV function and mass quantification derived from cardiac dual-source CT (DSCT) exams with those obtained by MRI in heart transplant recipients. Twelve heart transplant recipients who underwent cardiac DSCT and MRI examination were included. Double-oblique short-axis 8-mm slice ...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-008-0949-2
更新日期:2008-09-01 00:00:00
abstract:OBJECTIVES:To clarify the changes in organic anion-transporting polypeptide 8 (OATP8) expression and enhancement ratio on gadoxetic acid-enhanced MR imaging in hepatocellular nodules during multistep hepatocarcinogenesis. METHODS:In imaging analysis, we focused on 71 surgically resected hepatocellular carcinomas (well...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-011-2165-8
更新日期:2011-10-01 00:00:00
abstract:OBJECTIVE:To compare image quality and radiation dose using Adaptive Statistical Iterative Reconstruction (ASiR) and Filtered Back Projection (FBP) in patients weighing ≥ 91 kg. METHODS:In this Institution Review Board-approved retrospective study, single-phase contrast-enhanced abdominopelvic CT examinations of 100 a...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-012-2424-3
更新日期:2012-08-01 00:00:00
abstract:OBJECTIVE:To evaluate the integrity of endometrial enhancement after magnetic resonance imaging-guided high-intensity focused ultrasound (MR-HIFU) ablation of submucosal uterine fibroids based on contrast-enhanced MRI findings, and to identify the risk factors for endometrial impairment. METHODS:In total, 117 submucos...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-017-4765-4
更新日期:2017-09-01 00:00:00
abstract::The effect of stereotactic thalamotomy was assessed with pre- and postoperative functional magnetic resonance imaging (fMRI) under motor stimulation. A patient with unilateral essential tremor (ET) of the left arm underwent stereotactically guided thalamotomy of the right ventral intermediate thalamic nucleus (VIM). F...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-006-0211-8
更新日期:2006-10-01 00:00:00
abstract:OBJECTIVE:This study aimed to determine whether characteristics detected by multi-detector computed tomography (MDCT) were predictive of highly infectious, smear-positive, active pulmonary tuberculosis (PTB). METHODS:Among 124 patients with active PTB, 84 had positive (group 1) and 40 had negative (group 2) smear resu...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-010-1796-5
更新日期:2010-09-01 00:00:00
abstract:OBJECTIVES:To evaluate the diagnostic performance of a deep learning algorithm for automated detection of small 18F-FDG-avid pulmonary nodules in PET scans, and to assess whether novel block sequential regularized expectation maximization (BSREM) reconstruction affects detection accuracy as compared to ordered subset e...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-019-06498-w
更新日期:2020-04-01 00:00:00
abstract::The purpose was to assess the diagnostic accuracy of a hand-held Doppler ultrasound (US) machine for the bedside detection of liver and vascular abnormalities after liver transplantation in the intensive care unit. The IRB approved this study, and written informed consent was obtained from all patients or the patient'...
journal_title:European radiology
pub_type: 临床试验,杂志文章
doi:10.1007/s00330-009-1417-3
更新日期:2009-10-01 00:00:00
abstract:OBJECTIVE:Detection and pattern analysis of fascicular nerve hyperintensities in the T2-weighted image are the backbone of magnetic resonance neurography (MRN) as they may represent lesions of various etiologies. The aim of this study was to assess the prevalence of fascicular nerve hyperintensities in healthy individu...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-019-06145-4
更新日期:2019-07-01 00:00:00
abstract:OBJECTIVE:To determine the possible influence of segmentation margin on each step (feature reproducibility, selection, and classification) of the machine learning (ML)-based high-dimensional quantitative computed tomography (CT) texture analysis (qCT-TA) of renal clear cell carcinomas (RcCCs). MATERIALS AND METHODS:Fo...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-019-6003-8
更新日期:2019-09-01 00:00:00
abstract::The objective of this paper is to quantify the fatty degeneration (infiltration) of rotator cuff muscles with a new spectroscopic FLASH (SPLASH) sequence. Before planned surgery (reconstruction or muscle transfer), 20 patients (13 men, 7 women; 35-75 years) with different stages of rotator cuff disease underwent an MR...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-004-2410-5
更新日期:2004-12-01 00:00:00
abstract:OBJECTIVES:To demonstrate the feasibility of using chemical exchange saturation transfer (CEST) imaging to detect Parkinson's disease (PD) in patients at 3 Tesla. METHODS:Twenty-seven PD patients (17 men and 10 women; age range, 54-77 years) and 22 age-matched normal controls (13 men and 9 women; age range, 55-73 year...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-014-3241-7
更新日期:2014-10-01 00:00:00