Abstract:
:Human STAU1 is one member of the family of double-stranded RNA (dsRNA)-binding proteins. It is thought to function in transporting mRNA, controlling translation and eliciting mRNA decay in neurons, and to function in infection of influenza virus and human immunodeficiency virus type 1 (HIV-1). Four transcripts coding two isoforms have been identified before. In this study, we have isolated a novel transcript of STAU1, coding a novel isoform that has six amino acids more (SFPLKQ) than isoform a. In order to examine the tissue distribution of this novel isoform, we have performed RT-PCR experiments and the analysis showed that it was highly expressed in heart, liver, kidney and pancreas.
journal_name
Acta Biochim Poljournal_title
Acta biochimica Polonicaauthors
Fa-Hui N,Hai-Feng Y,Rui-Feng Q,Xin L,Cai-Bin Wsubject
Has Abstractpub_date
2008-01-01 00:00:00pages
473-8issue
3eissn
0001-527Xissn
1734-154Xpii
20081686journal_volume
55pub_type
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