Biomimetic polyesters and their role in ion transport across cell membranes.

Abstract:

:Syntheses of biomimetic low-molecular weight poly-(R)-3-hydroxybutanoate mediated by three types of supramolecular catalysts are presented. The utility of these synthetic polyesters for preparation of artificial channels in phospholipid bilayers capable of sodium and calcium ion transport across cell membranes, is discussed. Further studies on possible applications of these bio-polymers for manufacturing drugs of prolonged activity are under way.

journal_name

Acta Biochim Pol

journal_title

Acta biochimica Polonica

authors

Jedliński Z,Kurcok P,Adamus G,Juzwa M

subject

Has Abstract

pub_date

2000-01-01 00:00:00

pages

79-85

issue

1

eissn

0001-527X

issn

1734-154X

journal_volume

47

pub_type

杂志文章
  • Kinetic studies on the oxidation of nitrite by horseradish peroxidase and lactoperoxidase.

    abstract::The reaction of nitrite (NO2-) with horseradish peroxidase and lactoperoxidase was studied. Sequential mixing stopped-flow measurements gave the following values for the rate constants of the reaction of nitrite with compounds II (oxoferryl heme intermediates) of horseradish peroxidase and lactoperoxidase at pH 7.0, 1...

    journal_title:Acta biochimica Polonica

    pub_type: 杂志文章

    doi:

    authors: Gebicka L

    更新日期:1999-01-01 00:00:00

  • Tumors and the danger model.

    abstract::This article reviews the evidence for the danger model in the context of immune response to tumors and the insufficiency of the immune system to eliminate tumor growth. Despite their potential immunogenicity tumors do not induce significant immune responses which could destroy malignant cells. According to the danger ...

    journal_title:Acta biochimica Polonica

    pub_type: 杂志文章,评审

    doi:

    authors: Kowalczyk DW

    更新日期:2002-01-01 00:00:00

  • Cystic fibrosis is a risk factor for celiac disease.

    abstract:BACKGROUND:The coexistence of cystic fibrosis (CF) and celiac disease (CD) has been reported. To our knowledge there is no study directly comparing the incidence of CD in CF patients to that in the general population at the same time. There is no published data on genetic predisposition to CD in CF patients either. The...

    journal_title:Acta biochimica Polonica

    pub_type: 杂志文章

    doi:

    authors: Walkowiak J,Blask-Osipa A,Lisowska A,Oralewska B,Pogorzelski A,Cichy W,Sapiejka E,Kowalska M,Korzon M,Szaflarska-Popławska A

    更新日期:2010-01-01 00:00:00

  • Fluorescence decay time distribution analysis of cyclic enkephalin analogues. Influence of the solvents and configuration of amino acids in position 2 and 3 on changes in conformation.

    abstract::The lifetime distribution calculations were applied to study the influence of configuration of amino-acid residues in positions 2 and 3 on changes in conformation of the peptide chain of cyclic analogues of enkephalins containing a fluorescence energy donor and acceptor in different solvents. In all the solvents studi...

    journal_title:Acta biochimica Polonica

    pub_type: 杂志文章

    doi:

    authors: Malicka J,Groth M,Czaplewski C,Liwo A,Wiczk W

    更新日期:1999-01-01 00:00:00

  • Prediction of secondary structure of human haptoglobin.

    abstract::Secondary structure of alpha (light) and beta (heavy) chains of human haptoglobin was proposed. The Chou-Fasman predictive method was used in conjunction with the hydrophobic character and hydropathy scale value assigned to each amino acid residue in the primary sequence of the protein. Moreover, by means of hydrophil...

    journal_title:Acta biochimica Polonica

    pub_type: 杂志文章

    doi:

    authors: Dobryszycka W,Kubisa W,Kubicz Z

    更新日期:1987-01-01 00:00:00

  • Regulation of RNA polymerase III transcription by Maf1 protein.

    abstract::Maf1 was the first protein discovered to regulate polymerase III RNA in yeast and because it is evolutionarily conserved, a Maf1 ortholog also serves to restrain transcription in mouse and human cells. Understanding the mechanism of the regulation has been made possible by recent studies showing that Maf1 is a nuclear...

    journal_title:Acta biochimica Polonica

    pub_type: 杂志文章,评审

    doi:

    authors: Cieśla M,Boguta M

    更新日期:2008-01-01 00:00:00

  • Enzyme activities in human breast tumours.

    abstract::The activities of six enzymes associated with carbohydrate metabolism were measured both in carcinomas and in normal breast tissues. The following differences were observed. 1. The carcinoma showed higher enzyme activities than the normal mammary tissue. 2. The ratios of glutamate dehydrogenase, hydroxybutyrate dehydr...

    journal_title:Acta biochimica Polonica

    pub_type: 杂志文章

    doi:

    authors: Rzymowska J

    更新日期:1992-01-01 00:00:00

  • Reduction of oxidative stress in adjuvant arthritis. Comparison of efficacy of two pyridoindoles: stobadine dipalmitate and SMe1.2HCl.

    abstract::The aim of this study was to evaluate the therapeutic potential of oxidative stress (OS) reduction by using pyridoindole (PI) antioxidants in adjuvant arthritis (AA). The substances tested were stobadine dipalmitate (STB) and SMe1. AA was used as animal model. The experiments included healthy animals, control arthriti...

    journal_title:Acta biochimica Polonica

    pub_type: 杂志文章

    doi:

    authors: Ponist S,Mihalova D,Jancinova V,Snirc V,Ondrejickova O,Mascia C,Poli G,Stancikova M,Nosal R,Bauerová K

    更新日期:2010-01-01 00:00:00

  • Overexpression of the yeast HAM1 gene prevents 6-N-hydroxylaminopurine mutagenesis in Escherichia coli.

    abstract::The base analogue 6-N-hydroxylaminopurine (HAP) is a potent mutagen in a variety of prokaryotic and eukaryotic organisms. Mutations in the yeast ham1 gene render the cells hypersensitive to the mutagenic effect of HAP. We have found that this gene has homologues in a variety of organisms from bacteria to man. We have ...

    journal_title:Acta biochimica Polonica

    pub_type: 杂志文章

    doi:

    authors: Kozmin SG,Leroy P,Pavlov YI

    更新日期:1998-01-01 00:00:00

  • Eriochrome black T as a dye for agarose gel electrophoresis.

    abstract::We found that it is possible to use eriochrome black T as a dye for agarose gel electrophoresis of DNA. The presence of the dye does not change the migration rate of DNA and does not influence the electrophoretical picture. ...

    journal_title:Acta biochimica Polonica

    pub_type: 杂志文章

    doi:

    authors: Obuchowski M,Wegrzyn G

    更新日期:1991-01-01 00:00:00

  • Stem cell biology: a never ending quest for understanding.

    abstract::Stem cells (SC) research is an important part of biotechnology that could lead to the development of new therapeutic strategies. A lot of effort has been put to understand biology of the stem cells and to find genes and subsequently proteins that are responsible for their proliferation, self-renewal and differentiatio...

    journal_title:Acta biochimica Polonica

    pub_type: 杂志文章,评审

    doi:

    authors: Majka M,Kucia M,Ratajczak MZ

    更新日期:2005-01-01 00:00:00

  • Internal force field in selected proteins.

    abstract::The fuzzy oil drop model suggests that the tertiary conformation of a protein - particularly a globular one - can be likened to a spherical micelle. During the folding process, hydrophilic residues are exposed on the surface, while hydrophobic residues are retained inside the protein. The resulting hydrophobicity dist...

    journal_title:Acta biochimica Polonica

    pub_type: 杂志文章

    doi:10.18388/abp.2019_2865

    authors: Ptak-Kaczor M,Banach M,Konieczny L,Roterman I

    更新日期:2019-11-20 00:00:00

  • Leonurus cardiaca L. herb--a derived extract and an ursolic acid as the factors affecting the adhesion capacity of Staphylococcus aureus in the context of infective endocarditis.

    abstract::The objective was an assessment of the impact of Leonurus cardiaca L. extract (LCE) and ursolic acid (UA) on the adhesive properties of Staphylococus aureus NCTC 8325 strain, expressing virulence factors important in the pathogenesis of infective endocarditis. The adhesion and biofilm formation of bacteria cultured in...

    journal_title:Acta biochimica Polonica

    pub_type: 杂志文章

    doi:

    authors: Micota B,Sadowska B,Podsędek A,Redzynia M,Różalska B

    更新日期:2014-01-01 00:00:00

  • Effect of maternal dietary supplementation with phytosterol esters on muscle development of broiler offspring.

    abstract::Recently, embryo muscle development, which is crucial for postnatal skeletal muscle growth, has been investigated widely. Nutrients in ovo were suggested to be critical in embryo muscle development since the chick growth mostly relies on nutrients in eggs at the early developmental stage. Phytosterol esters (PE), whic...

    journal_title:Acta biochimica Polonica

    pub_type: 杂志文章

    doi:10.18388/abp.2020_2884

    authors: Wang L,Zuo X,Zhao W,Zhou G,Luo L,Yang K,Shu G,Wang S,Gao P,Zhu X,Jiang Q,Wang L

    更新日期:2020-03-19 00:00:00

  • Effect of thyroid hormone on the myosin heavy chain isoforms in slow and fast muscles of the rat.

    abstract::The myosin heavy chain (MHC) was studied by biochemical methods in the slow-twitch (soleus) and two fast-twitch leg muscles of the triiodothyronine treated (hyperthyroid), thyroidectomized (hypothyroid) and euthyroid (control) rats. The changes in the contents of individual MHC isoforms(MHC-1, MHC-2A, MHC-2B and MHC-2...

    journal_title:Acta biochimica Polonica

    pub_type: 杂志文章

    doi:

    authors: Jakubiec-Puka A,Ciechomska I,Mackiewicz U,Langford J,Chomontowska H

    更新日期:1999-01-01 00:00:00

  • The synthesis of RNA and silk protein in Galleria mellonella silk glands.

    abstract::The silk protein synthesis in silk glands of Galleria mellonella is preceded by the increase of total RNA content. The levels of the main RNA classes: 28S and 18S rRNA, tRNA as well as poly(A) + RNA change proportionally to the total RNA pool of glands. The fibroin-like silk protein of molecular weight of about 240 00...

    journal_title:Acta biochimica Polonica

    pub_type: 杂志文章

    doi:

    authors: Michalik J,Sehnal F,Lassota Z

    更新日期:1984-01-01 00:00:00

  • Advanced oxidation protein products and inflammatory markers in liver cirrhosis: a comparison between alcohol-related and HCV-related cirrhosis.

    abstract::Advanced oxidation protein products (AOPPs) are protein markers of oxidative stress with pro-inflammatory properties that accumulated in liver cirrhosis. In the present study, we investigated the association between chronic inflammatory response triggered by AOPPs and the severity of liver disease as assessed by the C...

    journal_title:Acta biochimica Polonica

    pub_type: 杂志文章

    doi:

    authors: Zuwała-Jagiełło J,Pazgan-Simon M,Simon K,Warwas M

    更新日期:2011-01-01 00:00:00

  • Tissue- and stage-specific expression of a fatty acid binding protein-like gene from amphioxus Branchiostoma belcheri.

    abstract::A cDNA clone encoding an amphioxus fatty acid binding protein-like (AmphiFABPL) protein was isolated from a gut cDNA library of Branchiostoma belcheri. It contained a 423 bp open reading frame corresponding to a deduced protein of 140 amino acids with a predicted molecular mass of approximately 15.9 kDa. Phylogenetic ...

    journal_title:Acta biochimica Polonica

    pub_type: 杂志文章

    doi:

    authors: Wang Y,Zhang Y,Zhang S,Tian J,Jiang S

    更新日期:2008-01-01 00:00:00

  • Up-regulation of human PNPase mRNA by beta-interferon has no effect on protein level in melanoma cell lines.

    abstract::Human mitochondrial polynucleotide phosphorylase (hPNPase) is an exoribonuclease localized in mitochondria. The exact physiological function of this enzyme is unknown. Recent studies have revealed the existence of a relationship between induction of hPNPase mRNA and both cellular senescence and growth arrest of melano...

    journal_title:Acta biochimica Polonica

    pub_type: 杂志文章

    doi:

    authors: Gewartowski K,Tomecki R,Muchowski L,Dmochow Ska A,Dzwonek A,Malecki M,Skurzak H,Ostrowski J,Stepien PP

    更新日期:2006-01-01 00:00:00

  • Biocatalytic synthesis of δ-gluconolactone and ε-caprolactone copolymers.

    abstract::The biodegradability and biocompatibility properties of ε-caprolactone homopolymers place it as a valuable raw material, particularly for controlled drug delivery and tissue engineering applications. However, the usefulness of such materials is limited by their low hydrophilicity and slow biodegradation rate. In order...

    journal_title:Acta biochimica Polonica

    pub_type: 杂志文章

    doi:

    authors: Todea A,Badea V,Nagy L,Kéki S,Boeriu CG,Péter F

    更新日期:2014-01-01 00:00:00

  • Tissue-specific effect of refeeding after short- and long-term caloric restriction on malic enzyme gene expression in rat tissues.

    abstract::Restricting food intake to a level below that consumed voluntarily (85%, 70% and 50% of the ad libitum energy intake for 3 or 30 days) and re-feeding ad libitum for 48 h results in an increase of malic enzyme (ME) gene expression in rat white adipose tissue. The increase of ME gene expression was much more pronounced ...

    journal_title:Acta biochimica Polonica

    pub_type: 杂志文章

    doi:045103805

    authors: Stelmanska E,Korczynska J,Swierczynski J

    更新日期:2004-01-01 00:00:00

  • Collagenous constituents of amniotic fluid.

    abstract::The amniotic fluid (AF) was fractionated by dialysis, gel filtration and SDS/PAGE, and submitted to the assay of collagenous constituents. The collagenous character of peptides and proteins of amniotic fluid was confirmed by hydroxyproline (Hyp) assay and treatment with bacterial collagenase followed by electrophoresi...

    journal_title:Acta biochimica Polonica

    pub_type: 杂志文章

    doi:

    authors: Gogiel T,Bielecki DA,Bańkowski E

    更新日期:1998-01-01 00:00:00

  • Collagen, elastin and glycosaminoglycans in aortic aneurysms.

    abstract::The walls of human abdominal aortas and atherosclerosis-induced aneurysms contain similar amounts of collagen. The quantitative ratio between collagens of various types of this protein does not differ significantly either, whereas solubility of the collagen in aneurysmal wall and its susceptibility to the action of ED...

    journal_title:Acta biochimica Polonica

    pub_type: 杂志文章

    doi:

    authors: Sobolewski K,Wolańska M,Bańkowski E,Gacko M,Głowiński S

    更新日期:1995-01-01 00:00:00

  • Evaluation of the effects of antibiotics on cytotoxicity of EGFP and DsRed2 fluorescent proteins used for stable cell labeling.

    abstract::The use of fluorescent markers has proven to be an attractive tool in biological imaging. However, its usefulness may be confined by the cytotoxicity of the fluorescent proteins. In this article, for the first time, we have examined an influence of the antibiotics present in culture medium on cytotoxicity of the EGFP ...

    journal_title:Acta biochimica Polonica

    pub_type: 杂志文章

    doi:

    authors: Zakrzewska KE,Samluk A,Pluta KD,Pijanowska DG

    更新日期:2014-01-01 00:00:00

  • A novel homozygous mutation in the WNK1/HSN2 gene causing hereditary sensory neuropathy type 2.

    abstract::Hereditary sensory and autonomic neuropathy type 2 is a rare disorder caused by recessive mutations in the WNK1/HSN2 gene located on chromosome 12p13.33. Phenotype of the patients is characterized by severe sensory loss affecting all sensory modalities. We report a novel homozygous Lys179fsX182 (HSN2); Lys965fsX968 (W...

    journal_title:Acta biochimica Polonica

    pub_type: 杂志文章

    doi:

    authors: Potulska-Chromik A,Kabzińska D,Lipowska M,Kostera-Pruszczyk A,Kochański A

    更新日期:2012-01-01 00:00:00

  • Haplotype analysis of phenylalanine hydroxylase alleles in polish families with phenylketonuria.

    abstract::Eight polymorphic restriction enzyme sites at phenylalanine hydroxylase locus from the parental chromosomes in Polish families with phenylketonuria were analyzed. Among 28 chromosomes studied, we identified haplotypes found within the Danish population. Haplotype 2 has been found in 25% of affected alleles. One of the...

    journal_title:Acta biochimica Polonica

    pub_type: 杂志文章

    doi:

    authors: Jaruzelska J,Borski K,Riess O,Blin N,Słomski R

    更新日期:1989-01-01 00:00:00

  • Mitochondrial metabolite carrier family, topology, structure and functional properties: an overview.

    abstract::A set of metabolite carriers operates the traffic of numerous molecules consumed or produced in mitochondrial matrix and/or cytosolic compartments. As their existence has been predicted by the chemiosmotic theory, the first challenge, in the late sixties, was to prove their presence in the inner mitochondrial membrane...

    journal_title:Acta biochimica Polonica

    pub_type: 杂志文章,评审

    doi:

    authors: Sluse FE

    更新日期:1996-01-01 00:00:00

  • Hemagglutination inhibition antibody titers as a correlate of protection against influenza disease in the 2018/2019 epidemic season in Poland.

    abstract::The aim of this study was to determine the level of antibodies against hemagglutinin of influenza viruses in the sera of people in the seven age groups in the epidemic season 2018/2019 in Poland. The level of anti-hemagglutinin antibodies was determined by hemagglutination inhibition test (HAI). 1050 clinical samples ...

    journal_title:Acta biochimica Polonica

    pub_type: 杂志文章

    doi:10.18388/abp.2020_5088

    authors: Hallmann-Szelińska E,Szymański K,Łuniewska K,Kondratiuk K,Brydak LB

    更新日期:2020-03-17 00:00:00

  • Homology of the predicted secondary structures of the N-terminal fragments of preproteins.

    abstract::Secondary structures of the N-terminal fragments of 18 preproteins were analysed taking advantage of the method of Chou & Fasman (Biochemistry, 1974, 13, 222-245; J. Mol. Biol., 1977, 115, 135-175) and the known sequences of amino acid residues. Positions of alpha-helices, beta-sheet structures and beta-turns in the l...

    journal_title:Acta biochimica Polonica

    pub_type: 杂志文章

    doi:

    authors: Tłomak P,Nowak K

    更新日期:1981-01-01 00:00:00

  • The antioxidant quercetin protects HL-60 cells with high myeloperoxidase activity against pro-oxidative and apoptotic effects of etoposide.

    abstract::The protective action of quercetin against the pro-oxidant and apoptotic effect of etoposide was investigated in HL-60 cells with a high level of myeloperoxidase (MPO) activity and in cells treated with MPO inhibitor, 4-aminobenzoic acid hydrazide (ABAH). Quercetin significantly protected MPO-rich cells against the pr...

    journal_title:Acta biochimica Polonica

    pub_type: 杂志文章

    doi:

    authors: Papież MA,Krzyściak W

    更新日期:2014-01-01 00:00:00