Apoptosis of peripheral blood leucocytes in rabbits infected with different strains of rabbit haemorrhagic disease virus.

Abstract:

:The pathogenicity of RHDV (rabbit haemorrhagic disease virus) is mainly associated with its affinity to blood vessels, with causing disseminated intravascular coagulations (DIC), and with the stimulation of the host immune system. Moreover, there are implications suggesting that apoptosis may be a pivotal process in understanding the basis of viral haemorrhagic disease in rabbits - a serious infectious disease causing mortality to wild and domestic rabbits. The aim of this study is to evaluate, by means of flow cytometry, the dynamics of apoptosis in peripheral blood granulocytes and lymphocytes in rabbits experimentally infected with seven different strains of RHDV and so-called antigenic variants of RHDV denominated as RHDVa, i.e.: Hungarian 24V/89, 1447V/96, 72V/2003; Austrian 01-04, 237/04, V-412 and French 05-01. The results showed that all of the RHDV and RHDVa strains cause an increase in the number of apoptotic cells throughout the infection, which might indicate the need for further analysis of the importance of this process.

journal_name

Acta Biochim Pol

journal_title

Acta biochimica Polonica

authors

Niedźwiedzka-Rystwej P,Hukowska-Szematowicz B,Tokarz-Deptuła B,Trzeciak-Ryczek A,Działo J,Deptuła W

subject

Has Abstract

pub_date

2013-01-01 00:00:00

pages

65-9

issue

1

eissn

0001-527X

issn

1734-154X

pii

2012_347

journal_volume

60

pub_type

杂志文章
  • Molecular forms of alkaline phosphatase in particular segments of the small intestine of adult rat. Separation of three enzyme forms from jejunum.

    abstract::Rat duodenum and jejunum were found to contain three forms of alkaline phosphatase, F1, F2 and F3, and ileum two forms of this enzyme, F1 and F2. The procedure for separation of phosphatase F1, F2 and F3 from jejunum is presented. ...

    journal_title:Acta biochimica Polonica

    pub_type: 杂志文章

    doi:

    authors: Dupuis Y,Landiharintsoa L,Fournier P,Zelazowska E,Staroń I,Porembska Z

    更新日期:1986-01-01 00:00:00

  • Dendrimer-paclitaxel complexes for efficient treatment in ovarian cancer: study on OVCAR-3 and HEK293T cells.

    abstract::The present paper investigates the enhancement of the therapeutic effect of Paclitaxel (a potent anticancer drug) by increasing its cellular uptake in the cancerous cells with subsequent reduction in its cytotoxic effects. To fulfill these goals the Paclitaxel (PTX)-Biotinylated PAMAM dendrimer complexes were prepared...

    journal_title:Acta biochimica Polonica

    pub_type: 杂志文章

    doi:10.18388/abp.2017_2331

    authors: Yao H,Ma J

    更新日期:2018-01-01 00:00:00

  • Evaluation of p-phenylene-bis and phenyl dithiocarbamate sodium salts as inhibitors of mushroom tyrosinase.

    abstract::Two structurally related compounds, phenyl dithiocarbamate sodium salt (I) and p-phenylene-bis (dithiocarbamate) sodium salt (II) were prepared by reaction of the parent aniline and p-phenylenediamine with CS₂ in the presence of sodium hydroxide. These water soluble compounds were characterized by spectroscopic techni...

    journal_title:Acta biochimica Polonica

    pub_type: 杂志文章

    doi:

    authors: Amin E,Saboury AA,Mansouri-Torshizi H,Zolghadri S,Bordbar AK

    更新日期:2010-01-01 00:00:00

  • Collagenous constituents of amniotic fluid.

    abstract::The amniotic fluid (AF) was fractionated by dialysis, gel filtration and SDS/PAGE, and submitted to the assay of collagenous constituents. The collagenous character of peptides and proteins of amniotic fluid was confirmed by hydroxyproline (Hyp) assay and treatment with bacterial collagenase followed by electrophoresi...

    journal_title:Acta biochimica Polonica

    pub_type: 杂志文章

    doi:

    authors: Gogiel T,Bielecki DA,Bańkowski E

    更新日期:1998-01-01 00:00:00

  • In situ detection of DNA and mRNA of human cytomegalovirus to distinguish different forms of viral infection in leukocytes.

    abstract::In situ PCR and in situ reverse transcription PCR (RT-PCR) were applied to discriminate between latent and productive infection of human cytomegalovirus (HCMV) in leukocytes. We investigated 28 samples, in which viral pp65 antigen was detected only in the cytoplasm of leukocytes. Additionally we assayed 12 specimens l...

    journal_title:Acta biochimica Polonica

    pub_type: 杂志文章

    doi:

    authors: Zawilinska B,Bulek K,Kopec J,Kosz-Vnenchak M

    更新日期:2006-01-01 00:00:00

  • Recombinant angioarrestin secreted from mouse melanoma cells inhibits growth of primary tumours.

    abstract::Angioarrestin is a recently described anti-angiogenic protein whose expression is down-regulated in solid tumours of various origins. It has a sequence identical to angiopoietin related protein-1. In this study we investigated anti-tumour properties of angioarrestin in B16 (F10) melanoma tumour model. We constructed a...

    journal_title:Acta biochimica Polonica

    pub_type: 杂志文章

    doi:

    authors: Smagur A,Szary J,Szala S

    更新日期:2005-01-01 00:00:00

  • An introduction to DNA chips: principles, technology, applications and analysis.

    abstract::This review describes the recently developed GeneChip technology that provides efficient access to genetic information using miniaturised, high-density arrays of DNA or oligonucleotide probes. Such microarrays are powerful tools to study the molecular basis of interactions on a scale that would be impossible using con...

    journal_title:Acta biochimica Polonica

    pub_type: 杂志文章,评审

    doi:

    authors: Gabig M,Wegrzyn G

    更新日期:2001-01-01 00:00:00

  • The influence of L-norvalyl-N3-4-methoxyfumaroyl-L-2,3-diaminopropanoic acid, an antifungal agent, on mammalian cells in tissue culture.

    abstract::Murine leukemia L1210 cells contain active glucosamine 6-phosphate synthase inhibited by N3-4-methoxyfumaroyl-L-2,3-diaminopropanoic acid (FMDP). However, FMDP-peptides do not exhibit any cytotoxicity against these cells, HeLa S3 human cervical carcinoma cells, and LL2 murine Lewis lung carcinoma cells. It is suggeste...

    journal_title:Acta biochimica Polonica

    pub_type: 杂志文章

    doi:

    authors: Bontemps-Gracz M,Milewski S,Borowski E

    更新日期:1991-01-01 00:00:00

  • HPV16 E6 polymorphism and physical state of viral genome in relation to the risk of cervical cancer in women from the south of Poland.

    abstract::The aim of this study was to analyse the correlation between HPV16 E6 variants and the physical status of viral genome (integrated, mixed, episomal) among patients with cervical cancer (n=40) and low-grade squamous intraepithelial lesions - LSIL (n=40). The study was performed on 80 HPV16 positive samples. HPV16 E6 va...

    journal_title:Acta biochimica Polonica

    pub_type: 杂志文章

    doi:10.18388/abp.2016_1364

    authors: Szostek S,Zawilinska B,Klimek M,Kosz-Vnenchak M

    更新日期:2017-01-01 00:00:00

  • Effect of extracellular pH and inhibitors on the gluconeogenesis and ammoniagenesis relationship in rat kidney cortex slices.

    abstract::1. Gluconeogenesis from glutamine, fumarate, pyruvate, glutamine plus fumarate, and glutamine plus pyruvate, was generally higher at pH 7.1 than at pH 7.4 and 7.7, whereas ammoniagenesis did not depend on the pH of the medium. 2. The intermediates of the Krebs cycle decreased ammonia formation from glutamine, raising ...

    journal_title:Acta biochimica Polonica

    pub_type: 杂志文章

    doi:

    authors: Strzelecki T,Rogulski J

    更新日期:1977-01-01 00:00:00

  • Relation of the polymorphism of cyp51A sequence and the susceptibility of Aspergillus fumigatus isolates to triazoles determined by commercial gradient test (Etest) and by reference methods.

    abstract::The aim of this study was to evaluate the accuracy of commercial gradient test (Etest) in the detection of triazole resistant Aspergillus fumigatus isolates using reference microdilution methods and the analysis of sequences of the cyp 51A gene. The study was performed on twenty clinical isolates which were identified...

    journal_title:Acta biochimica Polonica

    pub_type: 杂志文章

    doi:10.18388/abp.2017_1571

    authors: Nawrot U,Sulik-Tyszka B,Kurzyk E,Mroczyńska M,Włodarczyk K,Wróblewska M,Basak GW,Brillowska-Dąbrowska A

    更新日期:2017-01-01 00:00:00

  • The relationship between alkaline phosphatase and bone alkaline phosphatase activity and the growth hormone/insulin-like growth factor-1 axis and vitamin D status in children with growth hormone deficiency.

    abstract::The relationships between bone turnover, the growth hormone/insulin-like growth factor-1 (GH/IGF-1) axis and vitamin D are complex, but still not fully explained. The GH/IGF-1 axis and vitamin D can mutually modulate each other's metabolism and influence the activation of cell proliferation, maturation, and mineraliza...

    journal_title:Acta biochimica Polonica

    pub_type: 杂志文章

    doi:10.18388/abp.2017_2541

    authors: Witkowska-Sędek E,Stelmaszczyk-Emmel A,Majcher A,Demkow U,Pyrżak B

    更新日期:2018-01-01 00:00:00

  • Multidirectional effects of triterpene saponins on cancer cells - mini-review of in vitro studies.

    abstract::Triterpene saponins (saponosides) are found in a variety of higher plants and display a wide range of pharmacological activities, including expectorant, anti-inflamatory, vasoprotective, gastroprotective and antimicrobial properties. Recently, a potential anticancer activity of saponins has been suggested by their cyt...

    journal_title:Acta biochimica Polonica

    pub_type: 杂志文章,评审

    doi:10.18388/abp.2015_1089

    authors: Koczurkiewicz P,Czyż J,Podolak I,Wójcik K,Galanty A,Janeczko Z,Michalik M

    更新日期:2015-01-01 00:00:00

  • Adenosine 5'-triphosphate--a new regulator of annexin function. A hypothesis.

    abstract::The paradigm of annexins as phospholipid-binding proteins interacting with membranes in a calcium-dependent manner has been recently questioned in light of observations that some annexin isoforms may behave like membrane integral proteins or remain associated with their target membranes at low, resting, concentrations...

    journal_title:Acta biochimica Polonica

    pub_type: 杂志文章,评审

    doi:

    authors: Bandorowicz-Pikuła J,Pikuła S

    更新日期:1998-01-01 00:00:00

  • Soluble non-collagen proteins of bovine vitreous humour.

    abstract::Bovine vitreous humour contains 0.6 +/- 0.04 mg of proteins per cm3. Three main protein fractions were obtained by CM-cellulose chromatography and their homogeneity was confirmed by isoelectric focusing and SDS-gel electrophoresis. The Mr and pl values of the separated fractions were: fraction I, 67,000 and 4.02; frac...

    journal_title:Acta biochimica Polonica

    pub_type: 杂志文章

    doi:

    authors: Wolańska M,Bańkowski E

    更新日期:1989-01-01 00:00:00

  • Haplotype analysis of phenylalanine hydroxylase alleles in polish families with phenylketonuria.

    abstract::Eight polymorphic restriction enzyme sites at phenylalanine hydroxylase locus from the parental chromosomes in Polish families with phenylketonuria were analyzed. Among 28 chromosomes studied, we identified haplotypes found within the Danish population. Haplotype 2 has been found in 25% of affected alleles. One of the...

    journal_title:Acta biochimica Polonica

    pub_type: 杂志文章

    doi:

    authors: Jaruzelska J,Borski K,Riess O,Blin N,Słomski R

    更新日期:1989-01-01 00:00:00

  • Localization and role of RAP55/LSM14 in HeLa cells: a new finding on the mitotic spindle assembly.

    abstract::The MAP family includes large proteins like MAP-1A, MAP-1B, MAP-1C, MAP-2, and MAP-4 and smaller components like tau and MAP-2C. This article focuses on the relevant aspects of RAP55/LSM14 position with emphasis on its role in mitotic spindle formation and stability. In this context, the localization of RNA associated...

    journal_title:Acta biochimica Polonica

    pub_type: 杂志文章

    doi:10.18388/abp.2015_1107

    authors: Mili D,Georgesse D,Kenani A

    更新日期:2015-01-01 00:00:00

  • Recent progress in oligonucleotide synthesis.

    abstract::New blocking group combinations for the machine-aided oligoribonucleotide synthesis on solid phase material have been developed and tested regarding their general application. An acetal function for 2'-OH protection offers a series of advantages in the synthetic approach but special conditions have to be fulfilled in ...

    journal_title:Acta biochimica Polonica

    pub_type: 杂志文章,评审

    doi:

    authors: Pfleiderer W,Matysiak S,Bergmann F,Schnell R

    更新日期:1996-01-01 00:00:00

  • Is the mechanism of nitroglycerin tolerance associated with aldehyde dehydrogenase activity? A contribution to the ongoing discussion.

    abstract::The aim of the study presented here was an attempt to answer the question posed in the title: Is the mechanism of nitroglycerin tolerance associated with aldehyde dehydrogenase (ALDH) activity? Here, we investigated the effect of administration (separately or jointly) of lipoic acid (LA), nitroglycerin (GTN), and disu...

    journal_title:Acta biochimica Polonica

    pub_type: 杂志文章

    doi:10.18388/abp.2019_2908

    authors: Bilska-Wilkosz A,Kotańska M,Górny M,Filipek B,Iciek M

    更新日期:2019-12-28 00:00:00

  • Type III CRISPR complexes from Thermus thermophilus.

    abstract::Pathogen-specific acquired immunity in bacteria is mediated by the CRISPR (clustered regularly interspaced short palindromic repeats)-Cas systems. Thermus thermophilus strain HB8 contains CRISPR systems of several major subtypes (type I, IIIA and IIIB), and has become a widely studied model for CRISPR biology. We have...

    journal_title:Acta biochimica Polonica

    pub_type: 杂志文章

    doi:10.18388/abp.2016_1261

    authors: Szychowska M,Siwek W,Pawolski D,Kazrani AA,Pyrc K,Bochtler M

    更新日期:2016-01-01 00:00:00

  • A common cis-element in promoters of protein synthesis and cell cycle genes.

    abstract::Gene promoters contain several classes of functional sequence elements (cis elements) recognized by protein agents, e.g. transcription factors and essential components of the transcription machinery. Here we describe a common DNA regulatory element (tandem TCTCGCGAGA motif) of human TATA-less promoters. A combination ...

    journal_title:Acta biochimica Polonica

    pub_type: 杂志文章

    doi:

    authors: Wyrwicz LS,Gaj P,Hoffmann M,Rychlewski L,Ostrowski J

    更新日期:2007-01-01 00:00:00

  • Sustained virologic response and IL28B single-nucleotide polymorphisms in patients with chronic hepatitis C treated with pegylated interferon alfa and ribavirin.

    abstract:INTRODUCTION:Hepatitis C virus (HCV) infection is a global health problem which can lead to liver cirrhosis or hepatocellular carcinoma in one-fifth of chronically infected patients. MATERIALS AND METHODS:The study group consisted of 123 patients: 90 with HCV mono- and 33 with HIV/HCV co-infection, who were treated wi...

    journal_title:Acta biochimica Polonica

    pub_type: 杂志文章

    doi:

    authors: Jabłonowska E,Piekarska A,Koślińska-Berkan E,Omulecka A,Szymańska B,Wójcik K

    更新日期:2012-01-01 00:00:00

  • Effect of Mg2+ on kinetics of oxidation of pyrimidines in duplex DNA by potassium permanganate.

    abstract::Potassium permanganate oxidation of pyrimidine bases is often used to probe single-stranded regions in functional DNA-protein complexes. However, so far reactivity of these bases in double-stranded DNA has not been studied quantitatively. We have investigated the kinetics of oxidation of pyrimidines in supercoiled pDS...

    journal_title:Acta biochimica Polonica

    pub_type: 杂志文章

    doi:

    authors: Loziński T,Wierzchowski KL

    更新日期:2001-01-01 00:00:00

  • Influence of G2 arrest on the cytotoxicity of DNA topoisomerase inhibitors toward human carcinoma cells with different p53 status.

    abstract::We here report the influence of the cell cycle abrogator UCN-01 on RKO human colon carcinoma cells differing in p53 status following exposure to two DNA damaging agents, the topoisomerase inhibitors etoposide and camptothecin. Cells were treated with the two drugs at the IC90 concentration for 24 h followed by post-in...

    journal_title:Acta biochimica Polonica

    pub_type: 杂志文章

    doi:

    authors: Bozko P,Larsen AK,Raymond E,Skladanowski A

    更新日期:2002-01-01 00:00:00

  • Non-histone nuclear protein HMGN2 differently regulates the urothelium barrier function by altering expression of antimicrobial peptides and tight junction protein genes in UPEC J96-infected bladder epithelial cell monolayer.

    abstract::The urinary tract is vulnerable to frequent challenges from environmental microflora. Uropathogenic Escherichia coli (UPEC) makes a major contribution to urinary tract infection (UTI). Previous studies have characterized positive roles of non-histone nuclear protein HMGN2 in lung epithelial innate immune response. In ...

    journal_title:Acta biochimica Polonica

    pub_type: 杂志文章

    doi:10.18388/abp.2017_1622

    authors: Tian H,Miao J,Zhang F,Xiong F,Zhu F,Li J,Wang X,Chen S,Chen J,Huang N,Wang Y

    更新日期:2018-01-01 00:00:00

  • Kainate-evoked modulation of gene expression in rat brain.

    abstract::Kainate is a glutamate analog that produces neuronal excitation resulting in seizures within hours following its intraperitoneal injection into adult rats. Then, at 2-3 days after the treatment, neurodegeneration of apoptotic character can be observed in limbic system. As a consequence, plastic reorganization and glia...

    journal_title:Acta biochimica Polonica

    pub_type: 杂志文章,评审

    doi:

    authors: Kaminska B,Filipkowski RK,Biedermann IW,Konopka D,Nowicka D,Hetman M,Dabrowski M,Gorecki DC,Lukasiuk K,Szklarczyk AW,Kaczmarek L

    更新日期:1997-01-01 00:00:00

  • Diversity of the effect of phosphatidylcholine and sphingomyelin on adenylate deaminase from pig brain.

    abstract::Liposomes made of sphingomyelin were found to inhibit both ATP-activated and non-activated AMP deaminase from pig brain, in contrast to liposomes made of egg yolk phosphatidylcholine which exhibited an activating effect on the ATP-activated enzyme, being without effect on AMP deaminase in the absence of ATP. Dioleoylp...

    journal_title:Acta biochimica Polonica

    pub_type: 杂志文章

    doi:

    authors: Woźniak M,Purzycka-Preis J,Kossowska E,Zydowo MM

    更新日期:1987-01-01 00:00:00

  • MALDI-TOF MS - application in food microbiology.

    abstract::Microbiological purity control of food products is of great importance in the food industry. Contaminated food is often characterized by a deteriorated taste, smell, and appearance, and when consumed, it can pose a threat to human health and life. Also, contamination incurs huge financial losses to the food industry. ...

    journal_title:Acta biochimica Polonica

    pub_type: 杂志文章

    doi:10.18388/abp.2020_5380

    authors: Akimowicz M,Bucka-Kolendo J

    更新日期:2020-09-14 00:00:00

  • Antivirals--current trends in fighting influenza.

    abstract::Influenza virus infection is a major source of morbidity and mortality worldwide. Due to the variable effectiveness of existing vaccines, especially in the early stages of an epidemic, antiviral drugs represent the first line of defense against the virus. Currently, there are two major classes of anti-influenza drugs ...

    journal_title:Acta biochimica Polonica

    pub_type: 杂志文章,评审

    doi:

    authors: Król E,Rychłowska M,Szewczyk B

    更新日期:2014-01-01 00:00:00

  • Functional analyses of a low-penetrance risk variant rs6702619/1p21.2 associating with colorectal cancer in Polish population.

    abstract::Several studies employed the genome-wide association (GWA) analysis of single-nucleotide polymorphisms (SNPs) to identify susceptibility regions in colorectal cancer (CRC). However, the functional studies exploring the role of associating SNPs with cancer biology are limited. Herein, using chromatin immunoprecipitatio...

    journal_title:Acta biochimica Polonica

    pub_type: 杂志文章

    doi:10.18388/abp.2019_2775

    authors: Statkiewicz M,Maryan N,Kulecka M,Kuklinska U,Ostrowski J,Mikula M

    更新日期:2019-09-17 00:00:00