Abstract：
BACKGROUND:Gamma-irradiation of platelet concentrates may inactive contaminated lymphocytes and subsequently inhibit the synthesis of cytokine in platelet during storage. The aim of this study was to determine the effect of gamma-irradiation on the production of IL-8 and lymphocyte proliferation isolated from random donor platelet concentrates during 3-day storage. METHODS:In this study, we evaluated the effect of gamma-irradiation on both lymphocyte proliferative response and IL-8 production for 29 random donor platelet concentrates (RD-PCs). All PCs were prepared from single RD by platelet-rich plasma (PRP) method were divided in two groups: 1) non-irradiated RD-PCs (n = 13) and 2) irradiated RD-PCs (n = 16). The RD-PCs were treated by gamma-irradiation (30 Gy) on days 0 and 3. RESULTS:IL-8 increased in both groups after 3 days. It showed increase in concentration of IL-8 in irradiated and non-irradiated PCs during storage. Results of lymphocyte transformation test (LTT) indicated that the proliferation activity of lymphocyte was inhibited by gamma radiation. CONCLUSIONS:These data indicate that gamma irradiation inhibits proliferation of lymphocyte but does not inhibit production and accumulation of IL-8 during the storage of PCs.
journal_name
Arch Med Resjournal_title
Archives of medical researchauthors
Pourfathollah AA,Shaiegan M,Namiri M,Babae GRdoi
10.1016/j.arcmed.2008.05.004subject
Has Abstractpub_date
2008-08-01 00:00:00pages
590-3issue
6eissn
0188-4409issn
1873-5487pii
S0188-4409(08)00140-9journal_volume
39pub_type
杂志文章abstract：BACKGROUND AND AIMS:Streptococcus pneumoniae is the leading cause of acute otitis media, pneumonia, meningitis, and sepsis. The heptavalent pneumococcal conjugate vaccine (PCV7) was incorporated into the national immunization program in Mexico in 2008. The aim of the study was to analyze the frequency of S. pneumoniae ...
journal_title：Archives of medical research
pub_type： 杂志文章
doi：10.1016/j.arcmed.2015.02.004
更新日期：2015-02-01 00:00:00
abstract：BACKGROUND:We previously showed by using biochemical parameters that male Sprague-Dawley rats receiving a single intraperitoneal (i.p.) administration of alloxan (120 mg/kg body weight) with no further treatment recovered endocrine pancreatic function after 12 days. METHODS:Male Sprague-Dawley rats received an i.p. in...
journal_title：Archives of medical research
pub_type： 杂志文章
doi：10.1016/j.arcmed.2003.10.001
更新日期：2004-03-01 00:00:00
abstract：BACKGROUND AND AIMS:HTLV-I-transformed T cells secrete biologically active forms of vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (b-FGF). In addition, HTLV-I-transformed cells have a high capacity of adhesion to endothelial cells. METHODS:We measured the circulating endothelial progenit...
journal_title：Archives of medical research
pub_type： 杂志文章
doi：10.1016/j.arcmed.2011.01.002
更新日期：2011-01-01 00:00:00
abstract：BACKGROUND AND AIMS:Umbilical cord blood (UCB) has been identified as a good source of hematopoietic and nonhematopoietic stem cells that can be easily isolated. In the present study we investigated the possibility of whether stem cells in mononuclear UCB grown under defined conditions can produce progeny with neural p...
journal_title：Archives of medical research
pub_type： 杂志文章
doi：10.1016/j.arcmed.2011.10.003
更新日期：2011-10-01 00:00:00
abstract：:In contrast to the prophylactic HPV vaccines that exhibit great promise in reducing the burden of cervical cancer, there is limited progress towards the development of immune therapeutic strategies that would help those women who are already infected with high-risk HPV and do not benefit from the current vaccines. The...
journal_title：Archives of medical research
pub_type： 杂志文章,评审
doi：10.1016/j.arcmed.2009.07.003
更新日期：2009-08-01 00:00:00
abstract：BACKGROUND:Cardiac resynchronization therapy (CRT) has been shown to improve the clinical status and survival in congestive heart failure (CHF) patients, but little is known about its influence on neurohormonal profile. METHODS:Heart failure patients treated with CRT for moderate/severe heart failure were studied with...
journal_title：Archives of medical research
pub_type： 临床试验,杂志文章
doi：10.1016/j.arcmed.2008.07.004
更新日期：2008-10-01 00:00:00
abstract：BACKGROUND:A comprehensive understanding of the immune response induced by Mycobacterium bovis Bacille Calmette-Guérin in activation of protective T cells against tuberculosis is important to develop effective therapies to combat this disease. In this study, our experiments were designed to determine effects of transfo...
journal_title：Archives of medical research
pub_type： 杂志文章
doi：10.1016/s0188-4409(02)00463-0
更新日期：2003-01-01 00:00:00
abstract：:During the late 1940s, Alfred Jost demonstrated that mammalian sex differentiation begins in fetal testis, producing two factors necessary for the establishment of phenotypic males. Castrated embryos prior to testis differentiation led to phenotypic female differentiation. Jost proposed the existence of a testis-deter...
journal_title：Archives of medical research
pub_type： 杂志文章,评审
doi：10.1016/s0188-4409(01)00317-4
更新日期：2001-11-01 00:00:00
abstract：:Reports on simultaneous central and peripheral nervous system involvement in a patient with brucellosis are very rare. We report of one young female patient with a long history of consumption of non-pasteurized dairy products in which clinical and laboratory findings confirmed the existence of an active brucellosis wi...
journal_title：Archives of medical research
pub_type： 杂志文章
doi：
更新日期：1996-10-01 00:00:00
abstract：BACKGROUND:Associations between hyperuricemia, metabolic syndrome, cardiovascular disease and diabetes have been reported. Limited information, however, is available concerning the prevalence and correlates of hyperuricemia among Thai men and women. We sought to estimate the prevalence of hyperuricemia among a populati...
journal_title：Archives of medical research
pub_type： 杂志文章
doi：10.1016/j.arcmed.2006.03.008
更新日期：2006-10-01 00:00:00
abstract：BACKGROUND:Afternoon nap sleep was studied in 32 young male medical students who take customary naps to replace loss in nocturnal sleep. METHODS:From 16 subjects, a group called dreamers was formed, and the other 16 individuals were grouped as non-dreamers. Polygraphic recordings lasting 30 min were done at a fixed ti...
journal_title：Archives of medical research
pub_type： 临床试验,杂志文章
doi：
更新日期：1998-07-01 00:00:00
abstract：:Adhesion of trophozoites to target cells in the host intestine is the first of three consecutive steps (adherence, cytolytic effect and phagocytosis) involved in the invasion of colonic tissue by E. histolytica. To investigate the possible participation of the local secretory immune response in the interference with t...
journal_title：Archives of medical research
pub_type： 杂志文章
doi：
更新日期：1992-01-01 00:00:00
abstract：:The number of patients requiring lung transplantation is increasing, with a significant unmet demand for grafts. Ex vivo lung perfusion has been developed to increase graft recruitment. The major complications of lung transplantation include chronic allograft dysfunction (CLAD) whose cumulative incidence ranges from 4...
journal_title：Archives of medical research
pub_type： 杂志文章
doi：10.1016/j.arcmed.2015.03.004
更新日期：2015-04-01 00:00:00
abstract：:Trichomonas vaginalis cytoadherence is mediated by four adhesins (AP65, AP51, AP33 and AP23). Adhesin gene expression was previously shown to be up-regulated by iron. Therefore, a cDNA library was constructed from mRNA of T. vaginalis grown in a high-iron medium. Ten cDNA clones (three for AP65, one for AP51, and six ...
journal_title：Archives of medical research
pub_type： 杂志文章
doi：
更新日期：1995-01-01 00:00:00
abstract：:We report a study on the DNA organization in Entamoeba histolytica using a ribosomal DNA probe. The rDNA genes were found forming mers which were separated in a typical ladder pattern by pulse field electrophoresis. DNA rosette structures were visualized through electron microscopy in DNA eluted from bands recognized ...
journal_title：Archives of medical research
pub_type： 杂志文章
doi：
更新日期：1997-04-01 00:00:00
abstract：BACKGROUND:Quinolone-induced mutagenesis in the Salmonella typhimurium hisG48 strains suggests that these antibiotics are oxygen free radical generators. The use of beta-carotene as antioxidant was evaluated as an alternative to reduce oxidative cell damage in patients who need therapy with nalidixic acid, norfloxacin,...
journal_title：Archives of medical research
pub_type： 杂志文章
doi：10.1016/s0188-4409(00)00046-1
更新日期：2000-03-01 00:00:00
abstract：BACKGROUND AND AIMS:In previous studies, the Pro12Ala polymorphism in the peroxisome proliferator-activated receptor gamma 2 (PPAR-γ2) was shown to be associated with both lipid metabolism and longevity. We examined whether the polymorphism continued to be associated with abnormal levels of serum lipid/lipoprotein amon...
journal_title：Archives of medical research
pub_type： 杂志文章
doi：10.1016/j.arcmed.2011.09.010
更新日期：2011-10-01 00:00:00
abstract：:Gene therapy holds great promise. Somatic gene therapy has the potential to treat a wide range of disorders, including inherited conditions, cancers, and infectious diseases. Early progress has already been made in the treatment of a range of disorders. Ethical issues surrounding somatic gene therapy are primarily tho...
journal_title：Archives of medical research
pub_type： 杂志文章,评审
doi：10.1016/S0188-4409(03)00070-5
更新日期：2003-07-01 00:00:00
abstract：:The effect of electric field stimulation for promoting axonal growth between sural to facial nerve grafts in cases of congenital permanent facial palsy associated with hemifacial microsomia was studied. For this purpose, a total of 17 patients with unilateral congenital permanent facial palsy associated with hemifacia...
journal_title：Archives of medical research
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1996-04-01 00:00:00
abstract：:The communication discusses COVID-19 triggered reverse migration in India. India has witnessed the second largest mass migration in its history after the Partition of India in 1947, where more than 14 million people were displaced and migrated to India and Pakistan respectively, depending on their religious faiths. Th...
journal_title：Archives of medical research
pub_type： 杂志文章
doi：10.1016/j.arcmed.2020.06.003
更新日期：2020-10-01 00:00:00
abstract：OBJECTIVE:The aim of the study was to analyze, using a decision analysis approach, the probability of severity of illness due to delayed utilization of health services and inappropriate hospital medical treatment during the 2009 AH1N1 influenza epidemic in Mexico. METHODS:Patients with influenza AH1N1 confirmed by the...
journal_title：Archives of medical research
pub_type： 杂志文章
doi：10.1016/j.arcmed.2017.06.007
更新日期：2017-04-01 00:00:00
abstract：:The incidence of memories of events during the total intravenous general anesthesia is studied in a 400 adult patient group in order to establish the influence of the included doses of drugs in this scheme, upon the mentioned incidence. The anesthetic method included propofol, fentanyl and vecuronium. Two groups of pa...
journal_title：Archives of medical research
pub_type： 临床试验,杂志文章
doi：
更新日期：1994-01-01 00:00:00
abstract：:Three exoglucanase genes have been described in Saccharomyces cerevisiae. The bulk of the exoglucanase (EXO) activity is encoded by the EXG1 gene, whose primary gene product is differentially glycosylated during its transit to the cell surface to yield three isoenzymes: EXOI, EXOII and EXOII1/2. EXOII, the major isoen...
journal_title：Archives of medical research
pub_type： 杂志文章,评审
doi：
更新日期：1993-10-01 00:00:00
abstract：:It is likely that monosodium glutamate (MSG) is the excitotoxin that has been most commonly employed to characterize the process of excitotoxicity and to improve understanding of the ways that this process is related to several pathological conditions of the central nervous system. Excitotoxicity triggered by neonatal...
journal_title：Archives of medical research
pub_type： 杂志文章,评审
doi：10.1016/j.arcmed.2014.11.014
更新日期：2014-11-01 00:00:00
abstract：BACKGROUND:We assessed the auditory function of 94 patients with type 2 diabetes mellitus and 94 age- and sex-matched healthy subjects. METHODS:To study the influence of the clinical characteristics of the disease on the auditory function, after a clinical interview with ophthalmological assessment, subjects were eval...
journal_title：Archives of medical research
pub_type： 杂志文章
doi：10.1016/j.arcmed.2005.02.002
更新日期：2005-09-01 00:00:00
abstract：BACKGROUND:The aim of this study was to provide insight into the interpretation of CK-MB data after major noncardiac surgery. METHODS:Some 3,321 patients who underwent major non-emergent noncardiac procedures (orthopedic 31%, intrathoracic 12%, vascular 22%, other 35%) were studied. All patients had at least two CK sa...
journal_title：Archives of medical research
pub_type： 杂志文章
doi：
更新日期：1998-04-01 00:00:00
abstract：BACKGROUND:Hyperlipidemia is a risk factor for atherosclerotic events. Differences in lipid levels may exist in different races. Han is the largest group and Zhuang is the largest minority among the 56 nationalities in China. Geographically and linguistically, Zhuang can be classified into 43 ethnic subgroups, among wh...
journal_title：Archives of medical research
pub_type： 杂志文章
doi：10.1016/j.arcmed.2005.12.005
更新日期：2006-08-01 00:00:00
abstract：:Mongolian gerbils were inoculated intracecally with E. histolytica trophozoites cultured monoxenically. During the first hours of interaction an increase in mucus production was observed. Microulcerative mucosal lesions appeared 24 to 72 h post-inoculation. Inflammatory infiltrate and edema of the lamina propria were ...
journal_title：Archives of medical research
pub_type： 杂志文章
doi：
更新日期：1992-01-01 00:00:00
abstract：BACKGROUND:Exercise duration of constant-load endurance tests has been recently demonstrated to be more sensitive in detecting the changes after bronchodilator administration than either walking distance or peak oxygen uptake in patients with COPD. In the present study, we questioned whether exercise duration of progre...
journal_title：Archives of medical research
pub_type： 杂志文章
doi：10.1016/j.arcmed.2007.02.004
更新日期：2007-11-01 00:00:00
abstract：BACKGROUND AND AIMS:Distal renal tubular acidosis (dRTA) is characterized by a reduced ability to acidify urine, variable hyperchloremic hypokalemic metabolic acidosis, nephrocalcinosis, and nephrolithiasis. Mutations in the SLC4A1 gene have been found to cause either autosomal dominant (AD) or autosomal recessive (AR)...
journal_title：Archives of medical research
pub_type： 杂志文章
doi：10.1016/j.arcmed.2012.05.001
更新日期：2012-05-01 00:00:00
