Abstract:
BACKGROUND:Associations between hyperuricemia, metabolic syndrome, cardiovascular disease and diabetes have been reported. Limited information, however, is available concerning the prevalence and correlates of hyperuricemia among Thai men and women. We sought to estimate the prevalence of hyperuricemia among a population of patients receiving annual health exams and to evaluate its relationship with metabolic syndrome (MetS). METHODS:We conducted a cross-sectional study of 1,381 patients (376 men and 1,005 women) who first participated in annual health examinations at the Preventive Medicine Clinic of the King Chulalongkorn Memorial Hospital in Bangkok, Thailand during the period July 1999 through February 2000. Hyperuricemia was defined as >7.0 mg/dL in men and >6.0 mg/dL in women. MetS was defined using the modified ATP III criteria. RESULTS:The overall prevalence of the hyperuricemia was 10.6%. The condition was more common in men than in women (18.4 vs. 7.8%). Among women, serum uric acid was statistically significantly correlated with body mass index (BMI), systolic and diastolic blood pressure, high-density lipoprotein-cholesterol, triglyceride and fasting plasma glucose (all p <0.05). Men with serum uric acid concentrations >6.7 mg/dL (upper quartile) had a 3.91-fold increased in risk of MetS (95% CI:1.36-11.23), as compared with those who had concentrations <5.1 mg/dL (lowest quartile). Among women, the risk of MetS increased at least 2-fold for concentration of serum uric acid concentrations >4.0 mg/dL (p for trend <0.001). CONCLUSIONS:Hyperuricemia is prevalent among Thai men and women receiving routine health exams. Additionally, serum uric acid is positively associated with MetS.
journal_name
Arch Med Resjournal_title
Archives of medical researchauthors
Lohsoonthorn V,Dhanamun B,Williams MAdoi
10.1016/j.arcmed.2006.03.008subject
Has Abstractpub_date
2006-10-01 00:00:00pages
883-9issue
7eissn
0188-4409issn
1873-5487pii
S0188-4409(06)00148-2journal_volume
37pub_type
杂志文章abstract:BACKGROUND AND AIMS:We undertook this study to assess the effects of omega-3 polyunsaturated fatty acids (PUFAs) (administered at ≥2.7 g/day) for a minimum duration of 3 months on clinical outcomes in patients with rheumatoid arthritis (RA). METHODS:The authors surveyed randomized controlled trials (RCTs) that examine...
journal_title:Archives of medical research
pub_type: 杂志文章,meta分析
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abstract:BACKGROUND AND AIMS:In Brazil, sickle cell anemia (SCA) is one of the most common genetic disorders. The levels of fetal hemoglobin (HbF) may be influenced by the presence of genetic modifiers; among these are the β(S)-globin haplotypes, associated with the clinical heterogeneity presented by the disease. Patients with...
journal_title:Archives of medical research
pub_type: 杂志文章
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abstract::The incidence of memories of events during the total intravenous general anesthesia is studied in a 400 adult patient group in order to establish the influence of the included doses of drugs in this scheme, upon the mentioned incidence. The anesthetic method included propofol, fentanyl and vecuronium. Two groups of pa...
journal_title:Archives of medical research
pub_type: 临床试验,杂志文章
doi:
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journal_title:Archives of medical research
pub_type: 杂志文章
doi:
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journal_title:Archives of medical research
pub_type: 杂志文章,评审
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journal_title:Archives of medical research
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doi:
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abstract:BACKGROUND:Preimplantation genetic diagnosis (PGD) of monogenic autosomal hereditary disorders following assisted conception usually involves the removal of one or two blastomeres from preimplantation embryos. However, the amount of DNA from a single blastomere is insufficient to amplify the region of interest. Hence, ...
journal_title:Archives of medical research
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journal_title:Archives of medical research
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doi:
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journal_title:Archives of medical research
pub_type: 杂志文章
doi:
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abstract::Proteolytic activity was measured in lysates of four axenic and five xenic cultures of different strains of pathogenic E. histolytica, and in five non-pathogenic strains ("E. dispar") growing in xenic culture. There was no significant difference in total proteolytic activity, using either gelatin or albumin as substra...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:
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journal_title:Archives of medical research
pub_type: 杂志文章
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journal_title:Archives of medical research
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doi:
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journal_title:Archives of medical research
pub_type: 杂志文章
doi:10.1016/j.arcmed.2007.02.004
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journal_title:Archives of medical research
pub_type: 杂志文章,随机对照试验
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更新日期:2011-08-01 00:00:00
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journal_title:Archives of medical research
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journal_title:Archives of medical research
pub_type: 杂志文章
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更新日期:1999-05-01 00:00:00
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journal_title:Archives of medical research
pub_type: 杂志文章,评审
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更新日期:2017-11-01 00:00:00
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journal_title:Archives of medical research
pub_type: 杂志文章
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更新日期:1999-01-01 00:00:00
abstract::To know the activity of antimeningococcal immunoglobulin, Balb/c mice of 18-22 g of body weight were challenged with 5 serotype B strains of Neisseria meningitidis (Nm) isolated from patients of different Latin American countries. The specific antimeningococcal Ig was extracted from the serum of volunteers previously ...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:
更新日期:1997-01-01 00:00:00
abstract:BACKGROUND:The diuretic response has been shown to be a robust independent marker of cardiovascular outcomes in acute heart failure (ADHF) patients. The objectives of this clinical research, will aim are to: a) include diuresis in the formula for diuretic response (R-to-D); b) add to R-to-D the value of a pre-discharge...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:10.1016/j.arcmed.2018.08.007
更新日期:2018-04-01 00:00:00
abstract::Scorpion venom contains different types of peptides toxic to a variety of organisms whose molecular targets have been described as mainly ion-channels of excitable cells where they cause impairment of function. Based on mouse, cricket, and crustacean bioassays, specific toxins for each group of animals have been found...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:10.1016/s0188-4409(02)00370-3
更新日期:2002-07-01 00:00:00
abstract:BACKGROUND:It has been recently shown that oral administration of D002, a mixture of higher aliphatic primary alcohols isolated from beeswax, inhibits rat microsomal lipid peroxidation. This justified the present attempt to investigate whether D002 also exerts antioxidant effects in humans. METHODS:The effects of D002...
journal_title:Archives of medical research
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:2001-09-01 00:00:00
abstract:BACKGROUND:The present study was designed to examine whether resveratrol, a potent antioxidant, protects against renal ischemia-reperfusion (I/R) injury. METHODS:Wistar albino rats were unilaterally nephrectomized and subjected to 45 min of renal pedicle occlusion followed by 6 h of reperfusion. Resveratrol (RVT, 30 m...
journal_title:Archives of medical research
pub_type: 杂志文章
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