Abstract:
:Intracellular communication is an essential process in both embryological development and for the maintenance of normal tissue physiology. We have established the presence of this type of communication between endothelial cells and vascular smooth muscle cells in man and have here investigated the close contacts between endothelial and smooth muscle cells in the aorta of the 10-week-old human fetus. Transmission electron microscopy revealed myoendothelial contacts in the form of cytoplasmic projections, usually originating from the muscle cells. The nature of the cell-cell contacts was via simple appositions with an intercellular space of 6-15 nm. Myoendothelial contacts are sites for communication between elements of the intima and media, ensuring that paracrine secretion can occur and that the vessel wall, during growth and development, works as a unit.
journal_name
Arch Med Resjournal_title
Archives of medical researchauthors
Sosa-Melgarejo JA,Berry CLsubject
Has Abstractpub_date
1995-01-01 00:00:00pages
431-5issue
4eissn
0188-4409issn
1873-5487journal_volume
26pub_type
杂志文章abstract::Thanks to the results of the multiple completed and ongoing genome sequencing projects and to the newly available recombination-based cloning techniques, it is now possible to build gene repositories with no precedent in their composition, formatting, and potential. This new type of gene repository is necessary to add...
journal_title:Archives of medical research
pub_type: 杂志文章,评审
doi:10.1016/s0188-4409(02)00372-7
更新日期:2002-07-01 00:00:00
abstract:BACKGROUND AND AIMS:Cervical cancer is a common neoplastic disease affecting women worldwide. Expression of human papillomavirus type 16 (HPV-16) E6/E7 genes is frequently associated with cervical cancer, representing ideal targets for diagnostic and therapeutic strategies. Aptamers are oligonucleotide ligands capable ...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:10.1016/j.arcmed.2011.02.005
更新日期:2011-02-01 00:00:00
abstract:BACKGROUND:Estrogens exert profound effects on target tissues. These effects are mediated by two estrogen receptors (ER(alpha) and ER(beta)) that bind to specific DNA sequences in estrogen-dependent genes. Other molecules such as growth factors, transcription factors and some oncoproteins might interact with the estrog...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:10.1016/j.arcmed.2005.03.030
更新日期:2005-07-01 00:00:00
abstract::To determine the effects of a vegetarian diet with avocado as a source of monounsaturated fat on serum lipids, thirteen patients with phenotype II (twelve with IIa and one with IIb) dyslipidemia were included in a prospective, transversal and comparative study in which three four-week diets randomly assigned were asse...
journal_title:Archives of medical research
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1997-01-01 00:00:00
abstract::The objective of the study was to identify the patterns of recurrence in patients with squamous cell carcinoma of the anal canal (SCCAC) vs. the size of the primary tumor and its further possible impact on its treatment outcome. We reviewed 78 patients treated between 1975 to 1991. They were classified according to to...
journal_title:Archives of medical research
pub_type: 杂志文章,评审
doi:
更新日期:1995-10-01 00:00:00
abstract:BACKGROUND:There is a need to assess whether human immunodeficiency virus (HIV)-infected patients are more likely than noninfected individuals to have any of the specific lipoprotein combination profiles identified as the best predictors of future cardiovascular disease in the general population. METHODS:One hundred f...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:10.1016/j.arcmed.2007.06.012
更新日期:2008-01-01 00:00:00
abstract:BACKGROUND:Gamma-irradiation of platelet concentrates may inactive contaminated lymphocytes and subsequently inhibit the synthesis of cytokine in platelet during storage. The aim of this study was to determine the effect of gamma-irradiation on the production of IL-8 and lymphocyte proliferation isolated from random do...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:10.1016/j.arcmed.2008.05.004
更新日期:2008-08-01 00:00:00
abstract::Public and governmental concern regarding increasing cancer mortality trends in children in Mexico led us to investigate the current situation of childhood cancer in this country, as well as to discuss the reasons for which no decline in total and childhood cancer mortality has been documented during the past decades....
journal_title:Archives of medical research
pub_type: 杂志文章
doi:10.1016/s0188-4409(00)00094-1
更新日期:2000-09-01 00:00:00
abstract:BACKGROUND:Associations between hyperuricemia, metabolic syndrome, cardiovascular disease and diabetes have been reported. Limited information, however, is available concerning the prevalence and correlates of hyperuricemia among Thai men and women. We sought to estimate the prevalence of hyperuricemia among a populati...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:10.1016/j.arcmed.2006.03.008
更新日期:2006-10-01 00:00:00
abstract:BACKGROUND AND AIMS:Hypophosphatasia is a genetic disorder characterized by defective bone and tooth mineralization and a deficiency of serum and bone alkaline phosphatase activity. To date, few studies have identified gene mutations in Chinese patients with hypophosphatasia. We sought to characterize the clinical mani...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:10.1016/j.arcmed.2012.01.004
更新日期:2012-01-01 00:00:00
abstract::At the end of the year 2019, the novel coronavirus (2019-nCoV) was spreading in Wuhan, China, and the outbreak process has a high speed. It was recognized as a pandemic by the World Health Organization (WHO) on 11 March 2020. Coronaviruses are enveloped and single-stranded RNA that have several families including Seve...
journal_title:Archives of medical research
pub_type: 杂志文章,评审
doi:10.1016/j.arcmed.2020.04.022
更新日期:2020-07-01 00:00:00
abstract:BACKGROUND AND AIMS:We tested the effects of recombinant insulin-like growth factor-I (IGF-I) in an adipocyte model of HIV lipodystrophy and in an open label study on body composition and metabolism in patients with HIV lipodystrophy. METHODS:The effects of IGF-I on ritonavir-induced adipocyte cell death were studied ...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:10.1016/j.arcmed.2013.06.001
更新日期:2013-07-01 00:00:00
abstract:BACKGROUND:Lung adenocarcinoma (LAC) is a major worldwide cause of death by cancer, it shows high aggressiveness, functional decline, systemic compromise and severe cachexia, which might be counteracted by dietary redox-active phytochemicals. Therefore, our aim was to establish the anticancer effects of the oral intake...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:10.1016/j.arcmed.2019.11.006
更新日期:2020-01-01 00:00:00
abstract:BACKGROUND AND AIMS:HTLV-I-transformed T cells secrete biologically active forms of vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (b-FGF). In addition, HTLV-I-transformed cells have a high capacity of adhesion to endothelial cells. METHODS:We measured the circulating endothelial progenit...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:10.1016/j.arcmed.2011.01.002
更新日期:2011-01-01 00:00:00
abstract::Familial isolated glucocorticoid deficiency is a form of potentially lethal hereditary unresponsiveness to ACTH that manifests as primary adrenal insufficiency, usually without mineralocorticoid deficiency. Affected children commonly present with hyperpigmentation, recurrent hypoglycemia, chronic asthenia and failure ...
journal_title:Archives of medical research
pub_type: 杂志文章,评审
doi:10.1016/s0188-0128(99)00057-3
更新日期:1999-11-01 00:00:00
abstract:AIMS:To explore the effect of salvianolic acid B (Sal B) on regulation of SIRT3/FOXO1 signaling pathway in rats with non-alcoholic steatohepatitis (NASH). METHODS:Sixty Sprague Dawley (SD) rats were randomly divided into control, model and treatment groups. After 12 weeks of successful model establishment with high fa...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:10.1016/j.arcmed.2017.11.016
更新日期:2017-08-01 00:00:00
abstract:BACKGROUND AND AIMS:Vardenafil has been found to be potent in pulmonary hypertension; however, the underlying mechanisms remain poorly understood. To address this issue, we investigated the underlying mechanisms of vardenafil in the contribution of Ca(2+) signaling and mobilization in modifying vasoconstriction of pulm...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:10.1016/j.arcmed.2012.05.004
更新日期:2012-05-01 00:00:00
abstract:BACKGROUND:This investigation was undertaken to study the clinical characteristics and the humoral immune pattern in lymphedema patients undergoing O-beta-hydroxy-ethyl rutoside therapy. METHODS:A complete physical examination was performed on 27 lymphedema patients (postmastectomy and postphlebitis) and 17 healthy co...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:10.1016/s0188-4409(00)00272-1
更新日期:2001-03-01 00:00:00
abstract::As an initial step of investigation into the regulatory mechanisms of encystation in Entamoeba, we compared the protein profiles of newly formed cysts and trophozoites of E. invadens using high resolution two-dimensional PAGE and digitized video image analysis of silver stained gels. A total of 155 proteins unique to ...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:
更新日期:1992-01-01 00:00:00
abstract:BACKGROUND AND AIMS:Intestinal microbiota and soluble dietary fiber play an important role in intestinal microecology, which is closely related to gut motility. Regulating intestinal microecology comprised of fecal microbiota transplantation (FMT) or fiber supplementation is becoming a novel therapy for functional gast...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:10.1016/j.arcmed.2016.06.005
更新日期:2016-04-01 00:00:00
abstract::The amebicidal action of metronidazole is activated when the enzyme pyruvate:ferredoxin oxido-reductase transfers reducing equivalents to the nitro group of the drug. The enzyme is present in Entamoeba histolytica and other anaerobic parasites like Giardia and Trichomonas that lack mitochondria. The selectivity of the...
journal_title:Archives of medical research
pub_type: 杂志文章,评审
doi:
更新日期:1996-10-01 00:00:00
abstract:BACKGROUND:The diuretic response has been shown to be a robust independent marker of cardiovascular outcomes in acute heart failure (ADHF) patients. The objectives of this clinical research, will aim are to: a) include diuresis in the formula for diuretic response (R-to-D); b) add to R-to-D the value of a pre-discharge...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:10.1016/j.arcmed.2018.08.007
更新日期:2018-04-01 00:00:00
abstract:BACKGROUND AND AIMS:The present study analyzed the relationship between TP53 codon 72 polymorphisms and the clinical outcome of advanced gastric cancer patients receiving capecitabine plus paclitaxel chemotherapy. METHODS:Three hundred patients with advanced gastric cancer treated with paclitaxel and capecitabine comb...
journal_title:Archives of medical research
pub_type: 临床试验,杂志文章
doi:10.1016/j.arcmed.2015.12.001
更新日期:2016-01-01 00:00:00
abstract::In this report we show the chromosomal changes seen in a group of 303 Mexican patients with de novo Acute Myeloblastic Leukemia (AML). Two hundred forty-two patients were diagnosed and treated at two hospitals affiliated with the Instituto Mexicano del Seguro Social (IMSS). These are the Centro Medico Nacional Siglo X...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:
更新日期:1997-07-01 00:00:00
abstract:BACKGROUND AND AIMS:The use of automated peritoneal dialysis (APD) is increasing compared to continuous ambulatory peritoneal dialysis (CAPD). Surprisingly, little data about health benefits and cost of APD exist, and virtually no information comparing the cost-utility between CAPD and APD is available. We undertook th...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:10.1016/j.arcmed.2013.10.017
更新日期:2013-11-01 00:00:00
abstract:BACKGROUND:Studies in platelet of 5-HT uptake transporters have been performed using binding assay methodology designed for ligand-receptor interactions; however, uptake transporters present requirements that may question the validity of these particular binding assays. METHODS:To explore methodologic aspects that may...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:10.1016/j.arcmed.2003.03.001
更新日期:2003-09-01 00:00:00
abstract:BACKGROUND:It has been recently shown that oral administration of D002, a mixture of higher aliphatic primary alcohols isolated from beeswax, inhibits rat microsomal lipid peroxidation. This justified the present attempt to investigate whether D002 also exerts antioxidant effects in humans. METHODS:The effects of D002...
journal_title:Archives of medical research
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0188-4409(01)00315-0
更新日期:2001-09-01 00:00:00
abstract:BACKGROUND:Patients with certain types of stroke need urgent anticoagulation and it is extremely important for them to achieve fast and stable anticoagulant effect and receive individualized treatment during the initiation of warfarin therapy. METHODS:We conducted a prospective study among 210 acute stroke patients wh...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:10.1016/j.arcmed.2015.05.001
更新日期:2015-05-01 00:00:00
abstract::In this study we evaluated the usefulness of ferruginous bodies (FB) quantification in lung digest and histologic sections from 40 patients with a history of exposure to inorganic dusts. The patients were matched with 40 cases without occupational exposure. The samples of peripheral lung tissue were digested and all F...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:
更新日期:1992-01-01 00:00:00
abstract:BACKGROUND:PCI is an expensive procedure in our population and it implies a huge cost for the institutions and National Health Service. AIM OF THE STUDY:The main objective was to evaluate the technical and biological success of two stents designed in Mexico. METHODS:Ten York pigs, 4-6 months of age, underwent implant...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:10.1016/j.arcmed.2020.03.016
更新日期:2020-07-01 00:00:00