Abstract:
:The calculation of many derived fermentation variables such as the respiratory quotient (RQ) and mass transfer coefficient (K(L)a) requires the differences between the molar percentages of oxygen and carbon dioxide in the fermentor inlet and exit gas, called the %OUR and %CER. Noise and bias in %CER data is of order that in the exit gas carbon dioxide analysis. However, the relative amount of noise in the %OUR is one to two orders of magnitude greater than the noise in the raw oxygen analyses because the %OUR is calculated as a small difference between two large quantities. The noise in the %OUR is white with a Gaussian amplitude probability distribution of absolute standard deviation 0.0145. A chi-square filter of the %OUR data is shown to considerably improve the quality of the calculated RQ and K(L)a for a fermentation of Streptomyces clavuligerus.
journal_name
Biotechnol Bioengjournal_title
Biotechnology and bioengineeringauthors
Royce PN,Thornhill NFdoi
10.1002/bit.260400511subject
Has Abstractpub_date
1992-08-01 00:00:00pages
634-7issue
5eissn
0006-3592issn
1097-0290journal_volume
40pub_type
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