Abstract:
:The present study demonstrates that an abbreviated regimen of ganglioside treatments attenuates the behavioral impairments produced by unilateral lesions of the entorhinal cortex. Ganglioside treatments not only accelerate recovery of learned alternation on a Y-maze, but also reduce total errors and perseverative errors.
journal_name
Behav Brain Resjournal_title
Behavioural brain researchauthors
Ramirez JJ,Fass-Holmes B,Karpiak SE,Harshbarger R,Zengel D,Wright P,Valbuena Mdoi
10.1016/s0166-4328(05)80057-9subject
Has Abstractpub_date
1991-04-18 00:00:00pages
99-101issue
1eissn
0166-4328issn
1872-7549pii
S0166-4328(05)80057-9journal_volume
43pub_type
杂志文章abstract::Injections of carbachol (CCh) through a chronic cannula into the midbrain periaqueductal grey region (PAG) of the cat induced an emotional-defensive response (EDR) which was evaluated by duration and number of growls in a 30-min experimental session. That response was examined before and after injection of kainic acid...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/s0166-4328(89)80002-6
更新日期:1989-10-01 00:00:00
abstract::The water maze task has been developed to test spatial learning abilities in rats or mice, and is widely used. Though it has been reported before that numerous cognitive abilities are of importance for learning this task, poor performance is usually interpreted as an impairment of spatial memory formation. Previous in...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/s0166-4328(98)00134-x
更新日期:1999-04-01 00:00:00
abstract::Alcohol use disorder is pervasive and effects the health of millions. Identifying factors such as early life stress that contribute to the development of alcohol use disorder is therefore critical, especially those that contribute to adolescent drinking, a strong predictor of AUD development. The majority of prior stu...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2019.112449
更新日期:2020-02-17 00:00:00
abstract::The efferent and afferent connections of the V1/V2 border with the contralateral hemisphere have been examined using anatomical tracers. The V1/V2 border was found to exchange connections with the contralateral V2 area as well as a restricted strip of V1 lying adjacent to the V1/V2 border. Besides these homotopic proj...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/0166-4328(88)90027-7
更新日期:1988-08-01 00:00:00
abstract::Aging has diverse effects on different behaviors and underlying neural systems. This study utilized fear conditioning to determine if aged mice have deficits in the acquisition and/or retention of memories for contextual or cued fear conditioning, and to determine if galantamine, an acetylcholinesterase (AChE) inhibit...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2005.06.040
更新日期:2005-12-07 00:00:00
abstract::Microglia, the innate immune cells of the central nervous system, regulate brain development by promoting cell genesis, pruning synapses, and removing dying, newly-born or progenitor cells. However, the role of microglia in the early life programming of behavior under normal conditions is not well characterized. We us...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2016.09.006
更新日期:2017-01-01 00:00:00
abstract::Serotonin (5-HT) acts as a neurogenic compound in the developing brain; however serotonin altering drugs such as SSRIs are often prescribed to pregnant and lactating mothers. Early agonism of 5-HT receptors could alter the development of serotonergic circuitry, altering neurotransmission and behaviors mediated by 5-HT...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2013.07.043
更新日期:2013-09-15 00:00:00
abstract::This study's goal is to identify adaptations involving striatal glutamate (GLU) or dopamine (DA) receptors that may contribute to recovery of function following cortical injury. Unilateral aspiration of the medial agranular region of frontal cortex (AGm) in rats produces neglect of contralateral stimuli. Pharmacologic...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/0166-4328(95)00229-4
更新日期:1996-05-01 00:00:00
abstract::Deep brain stimulation (DBS) has gained interest as a potential therapy for advanced treatment-resistant dementia. However, possible targets for DBS and the optimal stimulation parameters are not yet clear. Here, we compared the effects of DBS of the CA1 sub-region of the hippocampus, mammillothalamic tract, anterior ...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2015.06.032
更新日期:2015-10-01 00:00:00
abstract::The study examined the relationship between risk-taking behavior during selection of monetary rewards and activations in the anterior cingulate cortex (ACC), orbitofrontal cortex (OFC) and medial prefrontal cortex (mPFC), brain regions that are associated with decision-making. Thirty-three adolescents with no personal...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2010.09.033
更新日期:2011-02-02 00:00:00
abstract::Rats were randomly assigned to enriched (EE) or standard environments (SE) at 21 or 73 days of age, for 17 days. Half of the rats of each rearing condition were trained in a radial maze (RM). At 38 days (pre-pubertal) or 90 days (young), rats were sacrificed and brain cytosolic and mitochondrial nitric oxide synthase ...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2007.06.024
更新日期:2007-12-03 00:00:00
abstract::In this study the relationship between 6-hydroxydopamine lesions of dopaminergic innervation of the lateral septum and schedule-induced polydipsia was examined. Animals with lesions were found to have a significant increase in water intake during a test involving an intermittent schedule of food delivery. Additional e...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/0166-4328(85)90012-9
更新日期:1985-01-01 00:00:00
abstract::Elements of the septo-preoptic basal forebrain complex, particularly the lateral and medial septum, the diagonal band of Broca, and the magnocellular preoptic area, have been linked to medial forebrain bundle (MFB) self-stimulation. This study examines the roles of these areas in MFB self-stimulation by temporarily in...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2006.12.005
更新日期:2007-03-12 00:00:00
abstract::S-100 beta, a gene triplicated in Down Syndrome (DS), is thought to play a role in development of the brain in general, and in the serotonergic neuronal system in particular. We have been studying an animal model of DS, based on overexpression of this gene. In the current study, we report on the social behaviors of th...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/s0166-4328(02)00373-x
更新日期:2003-05-15 00:00:00
abstract::We have found that protein malnutrition (PM) causes a significant impairment of memory-related behavior on the 15th and 20th day after the start of PM (5% casein) feeding in prepubertal mice but not in postpubertal mice, as measured by a passive-avoidance task. This impairment was almost completely reversed by merely ...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2005.08.024
更新日期:2006-02-15 00:00:00
abstract::In the present study we evaluated the involvement of nitric oxide (NO) system in the antidepressant-like effects of chronic lithium administration in the mouse forced swimming test (FST). Administration of lithium chloride (300 mg/L in drinking water for 21 days) had no effect on the immobility of mice in the FST, whe...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2008.12.032
更新日期:2009-06-08 00:00:00
abstract::Though accumulating literature implicates that cytokines are involved in the pathophysiology of mental disorders, the role of interleukin-6 (IL-6) in learning and memory functions remains unresolved. The present study was undertaken to investigate the effect of IL-6 on amygdala-dependent fear learning. Adult Wistar ra...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2014.08.052
更新日期:2014-12-15 00:00:00
abstract::It has been proposed that long-term potentiation (LTP), a form of activity-dependent modification of synaptic efficacy, may be a synaptic mechanism for certain types of learning. Recent studies on the insular cortex (IC), a region of the temporal cortex implicated in the acquisition and storage of conditioned taste av...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/s0166-4328(01)00329-1
更新日期:2002-02-01 00:00:00
abstract::Simultaneous spatial-discrimination thresholds of 6 human subjects were measured at luminances between 0.2 and 2000 cd/m2. Subjects were tested on a forced-choice discrimination task which required them to distinguish between test and control stimuli of high contrast square-wave gratings with similar space-average lum...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/0166-4328(84)90019-6
更新日期:1984-10-01 00:00:00
abstract::Previous research has shown that the dorsal immobility response (DIR) changes significantly in duration across the estrous cycle. In order to test whether gonadal steroid hormones act directly on the striatum to modulate this behavior, ovariectomized female Long-Evans hooded rats were given bilateral intrastriatal imp...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/s0166-4328(89)80111-1
更新日期:1989-11-01 00:00:00
abstract::A growing body of evidence suggests that activity of the mirror neuron system is dependent on the observer's motor experience of a given action. It remains unclear, however, whether activity of the mirror neuron system is also associated with the observer's motor experience in sports game. Therefore, the aim of the pr...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2011.04.053
更新日期:2011-10-01 00:00:00
abstract::We aimed to analyze whether hypertension and changes in nitric oxide (NO) generation are associated with alterations of locomotor activity in rats. Male Wistar rats treated with an inhibitor of NO synthase, NG-nitro-L-arginine methyl ester (L-NAME, 40 mg/kg/day) for 6 weeks, control Wistar rats, spontaneously hyperten...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2006.07.021
更新日期:2006-11-01 00:00:00
abstract::We developed a method to quantify the probability of a target neuron discharge following synchronous or asynchronous discharges among a pair of reference neurons. To illustrate this method, we simultaneously recorded three neurons having overlapping receptive fields in the somatosensory system: two reference neurons i...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/s0166-4328(02)00165-1
更新日期:2002-09-20 00:00:00
abstract::The anterior hippocampus has been implicated in associative memory, and along with hippocampal volume, this type of memory declines with age. However, few cross-sectional studies include middle-aged samples, making it unclear at what point these age-related changes occur. In addition, although men and women have been ...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2016.10.002
更新日期:2017-01-15 00:00:00
abstract::Despite considerable evidence for potential effects of estrogen on emotional processing, several studies of postmenopausal women who began hormone therapy (HT) remote from menopause report no effects of HT on emotional measures. As early HT initiation may preserve brain mechanisms, we examined effects of HT on emotion...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2011.09.012
更新日期:2012-01-01 00:00:00
abstract::Behavioural activation repeatedly induced by a stimulant in rodents can persist in the absence of the drug if the animals are tested in the context where the drug was previously given, a phenomenon often explained in terms of Pavlovian conditioning. The aim of this study was to verify whether the amplitude of the puta...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/s0166-4328(03)00106-2
更新日期:2003-10-17 00:00:00
abstract::The present study investigated the impact of a spared nerve injury (SNI) on the daily performance of rats tested in two instrumental conditioning procedures: the progressive ratio (PR) schedule of food reinforcement to study motivation for an appetitive stimulus, and the 5-choice serial reaction time task (5-CSRTT), a...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2015.02.050
更新日期:2015-06-01 00:00:00
abstract::We examined the long-term effects of administration of (S)-alpha-fluoromethylhistidine (FMH), a specific inhibitor of histidine decarboxylase, on the spontaneous locomotor activity, food intake and brain contents of histamine, catecholamines, serotonin and amino acids of ICR mice. The distance of ambulation and number...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/0166-4328(96)00059-9
更新日期:1995-12-14 00:00:00
abstract::Corticotropin-releasing factor (CRF) acts to promote stress-like physiological and behavioral responses and is mainly expressed in the paraventricular hypothalamic nucleus (PVN). Urocortin 1 (Ucn1) is also a ligand to CRF type 1 and 2 receptors that has been associated with the stress response. Ucn1 neurons are primar...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2014.06.014
更新日期:2014-09-01 00:00:00
abstract::Glucagon-like peptide-1 (GLP-1) decreased corticotropin-releasing factor (CRF)-induced behaviors in neonatal chicks, and serotonin is one of the possible mechanisms through which GLP-1 affects CRF-induced behaviors. The present experiments were conducted to confirm the effect of serotonin on CRF-induced behaviors. In ...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2003.08.005
更新日期:2004-05-05 00:00:00