Conditional cross-correlation analysis of thalamocortical neurotransmission.

Abstract:

:We developed a method to quantify the probability of a target neuron discharge following synchronous or asynchronous discharges among a pair of reference neurons. To illustrate this method, we simultaneously recorded three neurons having overlapping receptive fields in the somatosensory system: two reference neurons in the thalamic ventrobasal complex and one target neuron in the secondary somatosensory (SII) cortex. Our results show that focal cutaneous stimulation elicits synchronized discharges among thalamic neurons having similar place and submodality properties. Conditional cross-correlation analysis of the reference and target spike trains indicates that thalamic synchronization increases cortical responsiveness. This result suggests that neuronal synchronization plays a critical role in transmitting sensory information from thalamus to the cerebral cortex.

journal_name

Behav Brain Res

authors

Alloway KD,Roy SA

doi

10.1016/s0166-4328(02)00165-1

subject

Has Abstract

pub_date

2002-09-20 00:00:00

pages

191-6

issue

1-2

eissn

0166-4328

issn

1872-7549

pii

S0166432802001651

journal_volume

135

pub_type

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