A bitter PP1 fights the sweet polo.

Abstract:

:In a recent paper in Developmental Cell, Yamashiro et al. (2008) report that the PP1 regulatory subunit MYPT1 interacts with PLK1 and antagonizes essential mitotic functions of PLK1, at least in part by promoting the dephosphorylation of PLK1 at Thr210.

journal_name

Mol Cell

journal_title

Molecular cell

authors

Archambault V,Chen F,Glover DM

doi

10.1016/j.molcel.2008.05.012

subject

Has Abstract

pub_date

2008-06-06 00:00:00

pages

541-2

issue

5

eissn

1097-2765

issn

1097-4164

pii

S1097-2765(08)00363-8

journal_volume

30

pub_type

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