Redox Control of Mitochondrial Calcium Uptake.

Abstract:

:Dong et al. (2017) establish how the mitochondrial Ca2+ uniporter (MCU) integrates Ca2+ and oxidative stress signals by identifying a cysteine residue that controls MCU channel activity, a mechanism causing mitochondrial Ca2+ overload and cell death during oxidative stress.

journal_name

Mol Cell

journal_title

Molecular cell

authors

Demaurex N,Rosselin M

doi

10.1016/j.molcel.2017.02.029

subject

Has Abstract

pub_date

2017-03-16 00:00:00

pages

961-962

issue

6

eissn

1097-2765

issn

1097-4164

pii

S1097-2765(17)30166-1

journal_volume

65

pub_type

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