Induction of the endoplasmic reticulum stress protein GADD153/CHOP by capsaicin in prostate PC-3 cells: a microarray study.

abstract：:We investigated the role of acyl-CoAs during induction and maintenance of long-term potentiation in rat brain hippocampus. Changes of acyl-CoA and free fatty acids (FFA) in hippocampus were measured during tetraethylammonium (TEA)-induced LTP. Results indicated that concentrations of acyl-CoAs and FFAs in slices were ...

journal_title：Biochemical and biophysical research communications

authors： Zhang Q,Yoshida S,Sakai K,Liu J,Fukunaga K

更新日期：2000-01-07 00:00:00

abstract：:Resident mouse peritoneal macrophages in culture spontaneously secrete lipoprotein lipase. Secretion of lipoprotein lipase was 10-fold greater in thioglycollate-elicited and 6-fold greater in mineral oil-elicited macrophages. The increase in enzyme secretion was dependent on protein synthesis and glycosylation of the ...

journal_title：Biochemical and biophysical research communications

authors： Goldberg DI,Khoo JC

更新日期：1987-01-15 00:00:00

abstract：:Chromatography of a rat liver extract on DEAE-cellulose resulted in the near total loss of 3-hydroxyacyl-CoA epimerase activity. The activity was regained either when fractions were recombined or when purified crotonase was added to the early column fractions. A new enoyl-CoA hydratase present in these early fractions...

journal_title：Biochemical and biophysical research communications

authors： Smeland TE,Li JX,Chu CH,Cuebas D,Schulz H

更新日期：1989-05-15 00:00:00

abstract：:Y-box or inverted CCAAT box-binding proteins are multifunctional regulators of transcription and translation of several genes. Although YB-1 has been shown to play a key role in cell cycle, to date, there is no direct evidence. We disrupted one allele of Chk-YB-1b in a chicken pre-B lymphocyte cell line, DT40. Compare...

journal_title：Biochemical and biophysical research communications

authors： Swamynathan SK,Varma BR,Weber KT,Guntaka RV

更新日期：2002-08-16 00:00:00

abstract：:Here we analyzed Pfkfb3 and Pfkfb4 gene expression in rat testis development, isolated testicular cells and spermatozoa. Real time RT-PCR analysis during testis development showed the maximum expression of Pfkfb3 in pre-puber samples and of Pfkfb4 in adult samples. Western blot analysis showed that uPFK-2 protein, a p...

journal_title：Biochemical and biophysical research communications

authors： Gómez M,Navarro-Sabaté A,Manzano A,Duran J,Obach M,Bartrons R

更新日期：2009-09-18 00:00:00

abstract：:The ZntR protein from Escherichia coli is a member of the MerR-family of transcriptional regulatory proteins and acts as a hyper-sensitive transcriptional switch primarily in response to Zn(II) and Cd(II). The binding of metal-ions to ZntR initiates a mechanism that remodels the cognate promoter, increasing its affini...

journal_title：Biochemical and biophysical research communications

authors： Khan S,Brocklehurst KR,Jones GW,Morby AP

更新日期：2002-12-06 00:00:00

abstract：:Calcium regulates diverse cellular activities in plants through the action of calmodulin (CaM). By using (35)S-labeled CaM to screen an Arabidopsis seedling cDNA expression library, a cDNA designated as AtCh-CPN10 (Arabidopsis thaliana chloroplast chaperonin 10) was cloned. Chloroplast CPN10, a nuclear-encoded protein...

journal_title：Biochemical and biophysical research communications

authors： Yang T,Poovaiah BW

更新日期：2000-08-28 00:00:00

abstract：:Nerve Growth Factor is a 118 amino acid polypeptide that plays an important role in the differentiation and survival of neurons. The recent discovery that a mRNA that encodes beta Nerve Growth Factor is present in brain suggests that the Nerve Growth Factor gene may not only regulate gene expression of peripheral but ...

journal_title：Biochemical and biophysical research communications

authors： Rennert PD,Heinrich G

更新日期：1986-07-31 00:00:00

abstract：:We have identified and characterized the novel human transmembrane protein 9 (TMEM9). TMEM9 encodes a 183 amino-acid protein that contains an N-terminal signal peptide, a single transmembrane region, three potential N-glycosylation sites, and three conserved cys-rich domains in the N-terminus, but no hitherto known fu...

journal_title：Biochemical and biophysical research communications

authors： Kveine M,Tenstad E,Døsen G,Funderud S,Rian E

更新日期：2002-10-04 00:00:00

abstract：:The characteristics of carcinoembryonic antigen (CEA) molecules expressed by different cell types have been examined using cDNA transfection into cells of epithelial, neuroectodermal and hematopoietic origin. Variability in the CEA molecules was observed in terms of monoclonal antibody binding, apparent molecular weig...

journal_title：Biochemical and biophysical research communications

authors： Grimm T,Riethmüller G,Johnson JP

更新日期：1994-11-15 00:00:00

abstract：:Extracellular deoxycytidine (CdR) was previously shown to be salvaged into water soluble [1] and also into lipidic [2] precursors of phospholipids in stimulated lymphocytes and in lymphoma cells [3]. In this paper we have described that non-dividing murine macrophages salvaged not only 5-3H-CdR but also tritiated thym...

journal_title：Biochemical and biophysical research communications

authors： Hrabák A,Spasokukotskaja T,Temesi A,Staub M

更新日期：1993-05-28 00:00:00

abstract：:Metabolic assay buffers often omit bicarbonate, which is susceptible to alkalinisation in an open environment. Here, we assessed the effect of including bicarbonate in respirometry experiments. By supplementing HEPES-buffered media with low concentrations of bicarbonate, we found increased respiration in adipocytes an...

journal_title：Biochemical and biophysical research communications

authors： Krycer JR,Fisher-Wellman KH,Fazakerley DJ,Muoio DM,James DE

更新日期：2017-08-05 00:00:00

abstract：:Acivicin, a chlorinated amino acid antibiotic, is found to be remarkably effective in killing both the vector and the host form of the parasitic protozoa, Leishmania donovani, the causative agent for visceral leishmaniasis or Kala-azar. The ED50 (50 nM) for the pathogenic amastigote form in in vitro screening system i...

journal_title：Biochemical and biophysical research communications

authors： Mukherjee T,Roy K,Bhaduri A

更新日期：1990-07-31 00:00:00

abstract：:The rate limiting step in 5-fluorouracil catabolism is catalyzed by the enzyme dihydropyrimidine dehydrogenase. Since degradation of 5-fluorouracil decreases its efficacy in chemotherapy, the inhibition of its catabolism is a promising tool. We investigated the formation of micronuclei in vitro in mouse L5178Y cells. ...

journal_title：Biochemical and biophysical research communications

authors： Stopper H,Kühnel A,Podschun B

更新日期：1994-09-15 00:00:00

abstract：:Although chronic voluntary physical activity has been shown to enhance hippocampal brain-derived neurotrophic factor (BDNF) expression in animals, the effects of forced exercise on a treadmill have not been fully investigated. We assessed induction of c-fos and BDNF expression with acute exercise at different running ...

journal_title：Biochemical and biophysical research communications

authors： Soya H,Nakamura T,Deocaris CC,Kimpara A,Iimura M,Fujikawa T,Chang H,McEwen BS,Nishijima T

更新日期：2007-07-13 00:00:00

abstract：:Exogenous angiogenin undergoes rapid nuclear translocation in cultured human umbilical artery endothelial cells at 37 degrees C but not at 4 degrees C. Treatment of cells with colchicine, nocodazole and taxol, which disrupt the microtubule system, does not affect the nuclear translocation process of angiogenin, sugges...

journal_title：Biochemical and biophysical research communications

authors： Li R,Riordan JF,Hu G

更新日期：1997-09-18 00:00:00

abstract：:The Vpr protein of human immunodeficiency virus type 1 (HIV-1) is incorporated into the virion by the Gag polyprotein precursor Pr55gag. The importance of the p6gag sequence at the C-terminal end of Pr55gag has a crucial role in Vpr incorporation. To identify the Gag sequences directly involved in Vpr binding, we comp...

journal_title：Biochemical and biophysical research communications

authors： Li MS,Garcia-Asua G,Bhattacharyya U,Mascagni P,Austen BM,Roberts MM

更新日期：1996-01-05 00:00:00

abstract：:Resveratrol (3,5,4'-trihydroxystilbene) is a naturally occurring phytoalexin, found in grapes and wine, which has been reported to exert a variety of important pharmacological effects. We have investigated the activity of resveratrol on proliferation and differentiation of the promyelocitic cell line HL-60. A concentr...

journal_title：Biochemical and biophysical research communications

authors： Ragione FD,Cucciolla V,Borriello A,Pietra VD,Racioppi L,Soldati G,Manna C,Galletti P,Zappia V

更新日期：1998-09-08 00:00:00

abstract：:In many apoptotic cells, phosphatidylserine (PS), that is normally restricted to the inner membrane layer, is externalized and subsequently recognized by phagocytes. However, it has been unclear whether PS externalization is sufficient for phagocytosis induction. In a cultured cell line undergoing Fas-mediated apoptos...

journal_title：Biochemical and biophysical research communications

authors： Shiratsuchi A,Osada S,Kanazawa S,Nakanishi Y

更新日期：1998-05-19 00:00:00

abstract：:Recent studies suggest important roles for long noncoding RNAs as essential regulators of human cancer. GClnc1 was found to be upregulated in gastric cancer, playing oncogenic roles. However, the biological function and underlying mechanism of GClnc1 in osteosarcoma (OS) remain unclear. Here, we report that GClnc1 is ...

journal_title：Biochemical and biophysical research communications

authors： Sui Y,Han Y,Zhao X,Li D,Li G

更新日期：2018-12-09 00:00:00

abstract：:We describe the fusion of enhanced green fluorescent protein to the C-terminus of the HsdS DNA sequence-specificity subunit of the Type I DNA modification methyltransferase M.EcoKI. The fusion expresses well in vivo and assembles with the two HsdM modification subunits. The fusion protein functions as a sequence-speci...

journal_title：Biochemical and biophysical research communications

authors： Chen K,Roberts GA,Stephanou AS,Cooper LP,White JH,Dryden DT

更新日期：2010-07-23 00:00:00

abstract：:Cereblon (CRBN), the substrate receptor of an E3 ubiquitin ligase complex, is a target of thalidomide and thalidomide-derived immunomodulatory drugs (IMiDs). The binding of these IMiDs to CRBN alters the substrate specificity of the ligase, thereby mediating multiple effects that are exploited in cancer therapy. Howev...

journal_title：Biochemical and biophysical research communications

authors： Heim C,Maiwald S,Steinebach C,Collins MK,Strope J,Chau CH,Figg WD,Gütschow M,Hartmann MD

更新日期：2021-01-01 00:00:00

abstract：:Abnormal perpetual inflammatory response and sequential cytokine-induced prostaglandin E2 (PGE2) play important roles in the pathogenesis of rheumatoid arthritis (RA). The underlying regulatory mechanism, however, remain largely unknown. Here, we discovered that expression level of Metastasis associated protein 1 (MTA...

journal_title：Biochemical and biophysical research communications

authors： Wang H,Dong BW,Zheng ZH,Wu ZB,Li W,Ding J

更新日期：2016-04-29 00:00:00

abstract：:Several studies have shown that transplantation of embryonic stem cells into diabetic animals either improved or normalized blood glucose levels. In this study, we examined the dose-dependent effect of early (prediabetic stage) intravenous administration of human umbilical cord blood (HUCB) mononuclear cells on blood ...

journal_title：Biochemical and biophysical research communications

authors： Ende N,Chen R,Reddi AS

更新日期：2004-12-17 00:00:00

abstract：:Aplastic anemia (AA) is a serious blood system disease that threatens human health. At present, the main cause of this disease is believed to be immune hyperfunction. However, the specific metabolic mode involved in the occurrence of lymphocytes in AA is still unknown. In addition, whether rapamycin, a specific blocke...

journal_title：Biochemical and biophysical research communications

authors： Liu SL,Zhou YM,Tang DB,Zhou N,Zheng WW,Tang ZH,Duan CW,Chen J

更新日期：2019-10-15 00:00:00

abstract：:Alzheimer's disease (AD) is one of the most common neurodegenerative diseases leading to dementia. Although cytotoxicity of amyloid β peptides has been intensively studied within pathophysiology of AD, the physiological function of amyloid precursor protein (APP) still remains unclarified. We have shown previously tha...

journal_title：Biochemical and biophysical research communications

authors： Kwak YD,Hendrix BJ,Sugaya K

更新日期：2014-05-09 00:00:00

abstract：:Long noncoding RNAs (lncRNAs) have been identified to have more and more important roles in tumorigenesis and may be novel biomarker for cancer therapy. LncRNA TP73-AS1 is a novel identified lncRNA that has been demonstrated to be increased in several cancers, however, its function in bladder cancer remains unknown. T...

journal_title：Biochemical and biophysical research communications

authors： Tuo Z,Zhang J,Xue W

更新日期：2018-05-23 00:00:00

abstract：:Matrix metalloproteinases (MMPs) degrade extracellular matrix proteins, which may be responsible for enlargement of alveoli in chronic obstructive pulmonary disease (COPD) and remodeling of pulmonary tissue associated with chronic asthma. Here, we provide novel evidence that MMP-12 is expressed and secreted by normal ...

journal_title：Biochemical and biophysical research communications

authors： Lavigne MC,Thakker P,Gunn J,Wong A,Miyashiro JS,Wasserman AM,Wei SQ,Pelker JW,Kobayashi M,Eppihimer MJ

更新日期：2004-11-12 00:00:00

abstract：:Our previous study on the dynamic transcriptomes activated during human erythropoiesis suggested that transcription factor forkhead box O3 (FOXO3) possibly plays a role in erythroid differentiation. Functional studies in human cell line TF-1 indicated that FOXO3 knockdown repressed erythropoietin (EPO)-induced erythro...

journal_title：Biochemical and biophysical research communications

authors： Wang H,Li Y,Wang S,Zhang Q,Zheng J,Yang Y,Qi H,Qu H,Zhang Z,Liu F,Fang X

更新日期：2015-05-15 00:00:00

abstract：:Immortal hepatocytes were established from a CYP3A7-transgenic/p53-knockout mouse. The cells could be maintained with shorter doubling time after culture for 1 month. Detectable amounts of CYP3A7 mRNA and the activity of 7-propoxycoumarin O-depropylase, one of the representative CYP3A activities, were present in the i...

journal_title：Biochemical and biophysical research communications

authors： Shimoji M,Hattori K,Itoh S,Nakayama K,Katsuki M,Aizawa S,Yokoi T,Kamataki T

更新日期：1995-12-26 00:00:00