Abstract：
:Ortho-phthalaldehyde (OPA), a high-level disinfectant alternative to glutaraldehyde, was tested for efficacy against human hepatitis B virus (HBV) and hepatitis C virus (HCV) using surrogate animal viruses. HBV and HCV are the most prevalent human bloodborne viruses but have not yet been propagated in the laboratory. The surrogate viruses, duck hepatitis B virus (DHBV) and bovine viral diarrhea virus (BVDV), were used to assess the virucidal efficacy of OPA on HBV and HCV, respectively. After a timed exposure to the test disinfectant, the surrogate virus dried on a hard surface was neutralized and assayed to detect viable viruses using appropriate cell lines. A greater than 4-log(10) reduction in virus titer was demonstrated using dilute OPA solutions against dried DHBV and BVDV after 5 minutes of exposure at 20 degrees C. OPA was shown to be efficacious against surrogate viruses for human hepatitis B and hepatitis C virus. This is the first time that OPA efficacy has been demonstrated for HBV and HCV.
journal_name
Am J Infect Controljournal_title
American journal of infection controlauthors
Roberts CG,Chan-Myers HB,Favero MSdoi
10.1016/j.ajic.2007.08.005subject
Has Abstractpub_date
2008-04-01 00:00:00pages
223-6issue
3eissn
0196-6553issn
1527-3296pii
S0196-6553(07)00810-3journal_volume
36pub_type
杂志文章abstract：BACKGROUND:Because blood culture is a common test at our institution, we hoped to save money and reduce the risk of needlestick injury by modifying our current technique for the preparation of culture specimens without increasing the risk of contamination. METHODS: OBJECTIVE:To compare the contamination rates of bloo...
journal_title：American journal of infection control
pub_type： 杂志文章
doi：10.1016/s0196-6553(05)80176-2
更新日期：1992-06-01 00:00:00
abstract：BACKGROUND:To reach and engage hospitalists in the prevention of antimicrobial resistance, the Society of Hospital Medicine and the Centers for Disease Control and Prevention developed and conducted a quality improvement workshop based on the Centers for Disease Control and Prevention's Campaign to Prevent Antimicrobia...
journal_title：American journal of infection control
pub_type： 杂志文章
doi：10.1016/j.ajic.2007.03.006
更新日期：2007-12-01 00:00:00
abstract：BACKGROUND:Hospital-acquired Legionnaires' disease is associated with the presence of Legionella pneumophila in hospital water systems. In the United Kingdom, the Department of Health recommends maintaining hot water temperatures >55°C and cold water temperatures <20°C at the point of delivery to prevent proliferation ...
journal_title：American journal of infection control
pub_type： 杂志文章
doi：10.1016/j.ajic.2018.12.005
更新日期：2019-07-01 00:00:00
abstract：:Health care workers (HCWs) are susceptible to hospital acquired varicella zoster virus (VZV). We evaluated seroprevalence and predictive value of a history of varicella disease (VD) with VZV serology in HCWs in northern Israel. A total of 200 HCWs were enrolled. A high rate of seropositivity for VZV-IgG was found: 98....
journal_title：American journal of infection control
pub_type： 杂志文章
doi：10.1016/j.ajic.2007.06.004
更新日期：2008-08-01 00:00:00
abstract：:Health care-associated infections impact patient morbidity and mortality, and institutions adopt evidence-based measures to prevent and control such infections. In this study, professionals were observed during patient care under empirical contact precautions. A total of 243 observations were performed in which 39.5% ...
journal_title：American journal of infection control
pub_type： 杂志文章
doi：10.1016/j.ajic.2019.10.004
更新日期：2020-07-01 00:00:00
abstract：:The virucidal activity of 2 hand rubs proposed by the World Health Organization was studied in a quantitative suspension test for chemical disinfectants and antiseptics in human medicine (EN 14476). These formulations are recommended if no hand rubs with declared microbiological activity are available in health care s...
journal_title：American journal of infection control
pub_type： 杂志文章
doi：10.1016/j.ajic.2009.07.009
更新日期：2010-02-01 00:00:00
abstract：BACKGROUND:Total abdominal hysterectomy, a common operative procedure, is infrequently accompanied by incisional wound infection. No recent study has examined the excess hospital stay attributable to such infections. METHODS:This historical cohort study of cases and matched controls was performed in a tertiary care un...
journal_title：American journal of infection control
pub_type： 临床试验,杂志文章
doi：10.1016/0196-6553(93)90032-y
更新日期：1993-08-01 00:00:00
abstract：:This report describes a cluster of nosocomial infections with Pseudomonas aeruginosa in a neonatal intensive care nursery. All 5 cases of P aeruginosa infection were clustered in September 1999. Aggressive infection control measures were instituted, including installation of a user-friendly handwashing soap and enviro...
journal_title：American journal of infection control
pub_type： 杂志文章
doi：10.1067/mic.2002.121153
更新日期：2002-11-01 00:00:00
abstract：BACKGROUND:Contamination of bronchoalveolar lavage fluid is a major problem in the world. Although 2% glutaraldehyde (GA) is widely used as a disinfectant for bronchoscope cleaning, recently, GA-tolerant mycobacteria have been isolated, which makes this problem more complicated. METHODS:We studied the susceptibility t...
journal_title：American journal of infection control
pub_type： 杂志文章
doi：10.1016/j.ajic.2003.07.007
更新日期：2004-06-01 00:00:00
abstract：BACKGROUND:The incidence of postoperative surgical site infections (SSIs) is difficult to estimate because of the current trend of early discharge after surgery. Both operation-related and host factors should be taken into consideration in the prevention of SSIs. We wanted to determine the actual incidence of SSIs and ...
journal_title：American journal of infection control
pub_type： 临床试验,杂志文章
doi：10.1016/s0196-6553(97)90082-1
更新日期：1997-10-01 00:00:00
abstract：OBJECTIVE:Surgical site infections (SSIs) are a serious and costly post-op complication. Generating SSI rates often requires labor-intensive methods, but increasing numbers of publications reported SSI rates using administrative data. METHODS:Index laminectomy and spinal fusion procedures were identified using Canadia...
journal_title：American journal of infection control
pub_type： 杂志文章
doi：10.1016/j.ajic.2020.10.010
更新日期：2020-10-20 00:00:00
abstract：:Knowing where we have come from helps to decide where we should be going. Many principles and practices of modern infection control were developed in the nineteenth and early twentieth century. The story is one of halting, yet relentless, progress. The history of these discoveries and their application to infection co...
journal_title：American journal of infection control
pub_type： 历史文章,杂志文章
doi：10.1016/s0196-6553(81)80064-8
更新日期：1981-08-01 00:00:00
abstract：BACKGROUND:Pertussis is an underestimated disease. Several European countries have developed models to account for underreporting of pertussis. The aim of this study was to estimate pertussis underdetection and underreporting in pediatric patients attending primary health care centers (PHCCs). METHODS:We reviewed clin...
journal_title：American journal of infection control
pub_type： 杂志文章
doi：10.1016/j.ajic.2016.03.033
更新日期：2016-11-01 00:00:00
abstract：BACKGROUND:Increasing evidence indicates a strong association between occupational livestock contact and methicillin-resistant Staphylococcus aureus (MRSA) carriage. However, it remains unclear whether there are frequency-risk and duration-risk relations between occupational livestock contact and human MRSA carriage. ...
journal_title：American journal of infection control
pub_type： 杂志文章
doi：10.1016/j.ajic.2015.03.026
更新日期：2015-07-01 00:00:00
abstract：BACKGROUND:Thermally injured patients are at high risk for infections, including hospital acquired infections (HAIs). We modeled a twice-daily chlorhexidine gluconate (CHG) bath protocol aimed at decreasing HAIs. METHODS:Bathing with a 0.9% CHG solution in sterile water was provided twice daily as part of routine care...
journal_title：American journal of infection control
pub_type： 杂志文章
doi：10.1016/j.ajic.2013.08.015
更新日期：2014-02-01 00:00:00
abstract：BACKGROUND:The best strategy for active surveillance for methicillin-resistant Staphylococcus aureus (MRSA) remains unclear. We attempted to identify a risk factor score to predict MRSA colonization at hospital admission. METHODS:Data on 9 variables reported as risk factors for MRSA colonization were analyzed, and a r...
journal_title：American journal of infection control
pub_type： 杂志文章
doi：10.1016/j.ajic.2013.02.013
更新日期：2013-11-01 00:00:00
abstract：:One medical center in southern Taiwan faced an outbreak of nosocomial Legionnaires' disease; a total of 81 suspected cases were detected during an 8-month period. Baseline environmental surveillance showed that 80% of the distal sites in intensive care units (ICUs) were positive for Legionella pneumophila. Superheat-a...
journal_title：American journal of infection control
pub_type： 杂志文章
doi：10.1016/j.ajic.2004.12.008
更新日期：2005-12-01 00:00:00
abstract：BACKGROUND:Composition and diversity of intestinal microbial communities (microbiota) are generally accepted as a risk factor for poor outcomes; however, we cannot yet use this information to prevent adverse outcomes. METHODS:Stool was collected from 8 long-term acute care hospital patients experiencing diarrhea and 2...
journal_title：American journal of infection control
pub_type： 杂志文章
doi：10.1016/j.ajic.2016.01.003
更新日期：2016-07-01 00:00:00
abstract：:In a series of experiments, the barrier integrity of single and double vinyl and latex examination gloves were tested for dye and water leaks after being placed under stress. A total of 886 examination gloves (385 vinyl: single, 199; double, 186; and 501 latex: single, 290; double, 211) were tested with a standardized...
journal_title：American journal of infection control
pub_type： 杂志文章
doi：10.1016/0196-6553(94)90085-x
更新日期：1994-02-01 00:00:00
abstract：:To prevent central line-associated bloodstream infections (CLABSIs), leadership line care rounds (LLCRs) used the engage, educate, execute, and evaluate improvement model to audit compliance, identify barriers and opportunities, empower patients and families, and engage leadership. Findings of excellence and improveme...
journal_title：American journal of infection control
pub_type： 杂志文章
doi：10.1016/j.ajic.2017.08.032
更新日期：2018-02-01 00:00:00
abstract：BACKGROUND:Studies conducted in the first decade of the AIDS epidemic indicated that, in general, dentists had suboptimal levels of compliance with standard infection control practices, including work practices designed to reduce exposure to bloodborne pathogens. This study was designed to assess current rates of compl...
journal_title：American journal of infection control
pub_type： 杂志文章
doi：10.1016/s0196-6553(98)70058-6
更新日期：1998-02-01 00:00:00
abstract：:This article catalogs some of the Centers for Disease Control and Prevention's (CDC) more important information resource offerings, which make public health information accessible via computer and automated telephone systems and on electronic media (diskette and CD-ROM). We review mechanisms for (1) finding and retrie...
journal_title：American journal of infection control
pub_type： 杂志文章,评审
doi：10.1016/s0196-6553(96)90038-3
更新日期：1996-12-01 00:00:00
abstract：BACKGROUND:Room ventilation is a key determinant of airborne disease transmission. Despite this, ventilation guidelines in hospitals are not founded on robust scientific evidence related to the prevention of airborne transmission. METHODS:We sought to assess the effect of ventilation rates on influenza, tuberculosis, ...
journal_title：American journal of infection control
pub_type： 杂志文章
doi：10.1016/j.ajic.2011.02.014
更新日期：2011-12-01 00:00:00
abstract：BACKGROUND:Methicillin-resistant Staphylococcus aureus (MRSA) strains were isolated and characterized from environmental surfaces of two fire stations from two independent districts in the northwestern United States. After the first sampling and before the second sampling, education was provided, additional signage was...
journal_title：American journal of infection control
pub_type： 杂志文章
doi：10.1016/j.ajic.2010.09.008
更新日期：2011-06-01 00:00:00
abstract：OBJECTIVE:To describe successful termination of an outbreak of vancomycin-resistant Enterococcus faecium (VREfm) colonization within a neonatal service. SETTING:Multisite neonatal intensive care unit and special care nurseries within a single health care service. PARTICIPANTS:Forty-four cases of VREfm-colonized neona...
journal_title：American journal of infection control
pub_type： 杂志文章
doi：10.1016/j.ajic.2015.05.047
更新日期：2015-10-01 00:00:00
abstract：BACKGROUND:Occupational blood exposures among operating room personnel have been substantially underreported in incident reports. Recent research has indicated several common factors influencing exposure rates: surgical service (thoracic, neurosurgery, orthopedic), length of operation, and emergency status. METHODS:Th...
journal_title：American journal of infection control
pub_type： 杂志文章
doi：10.1016/0196-6553(93)90402-p
更新日期：1993-12-01 00:00:00
abstract：:We evaluated symptom documentation for 312 inpatients with bacteriuria by comparing information found in the chart with that obtained prospectively from the medical and nursing team caring for the patient. There was only moderate agreement (κ = 0.55), and only 77% of symptomatic patients had any symptom documented in ...
journal_title：American journal of infection control
pub_type： 杂志文章
doi：10.1016/j.ajic.2015.07.037
更新日期：2015-11-01 00:00:00
abstract：:We illustrate how genotyping of mycobacterial strains contributed to the discovery of an undetected outbreak of tuberculosis in a hospital ward, ruling out misleading assumptions of transmission chains. Genotyping should be taken into account in routine tests for the control of tuberculosis. ...
journal_title：American journal of infection control
pub_type： 杂志文章
doi：10.1016/j.ajic.2011.03.003
更新日期：2012-02-01 00:00:00
abstract：:The predominant form of life for the majority of microorganisms in any hydrated biologic system is a cooperative community termed a "biofilm." A biofilm on an indwelling urinary catheter consists of adherent microorganisms, their extracellular products, and host components deposited on the catheter. The biofilm mode o...
journal_title：American journal of infection control
pub_type： 杂志文章,评审
doi：10.1016/j.ajic.2003.08.005
更新日期：2004-05-01 00:00:00
abstract：BACKGROUND:Hand cleanliness is important in hospital infection control, but skin irritation from frequent alcohol-based hand rub use reduces compliance. We have compared a new copper biocide/Aloe vera-based biocidal hand rub (Xgel) with 7 commercially available hand rubs. METHODS:Hand rubs were cultured with human ski...
journal_title：American journal of infection control
pub_type： 杂志文章
doi：10.1016/j.ajic.2008.09.011
更新日期：2009-05-01 00:00:00
