Abstract：
BACKGROUND:Room ventilation is a key determinant of airborne disease transmission. Despite this, ventilation guidelines in hospitals are not founded on robust scientific evidence related to the prevention of airborne transmission. METHODS:We sought to assess the effect of ventilation rates on influenza, tuberculosis, and rhinovirus infection risk within 3 distinct rooms in a major urban hospital: a lung function laboratory, an emergency department negative-pressure isolation room, and an outpatient consultation room. Air-exchange rate measurements were performed in each room using CO2 as a tracer. The model developed by Gammaitoni and Nucci was used to estimate infection risk. RESULTS:Current outdoor air-exchange rates in the lung function laboratory and emergency department isolation room limited infection risks to 0.1%-3.6%. Influenza risk for individuals entering an outpatient consultation room after an infectious individual departed ranged from 3.6% to 20.7%, depending on the duration for which each person occupied the room. CONCLUSION:Given the absence of definitive ventilation guidelines for hospitals, air-exchange measurements combined with modeling afford a useful means of assessing, on a case-by-case basis, the suitability of room ventilation for preventing airborne disease transmission.
journal_name
Am J Infect Controljournal_title
American journal of infection controlauthors
Knibbs LD,Morawska L,Bell SC,Grzybowski Pdoi
10.1016/j.ajic.2011.02.014subject
Has Abstractpub_date
2011-12-01 00:00:00pages
866-72issue
10eissn
0196-6553issn
1527-3296pii
S0196-6553(11)00179-9journal_volume
39pub_type
杂志文章abstract：BACKGROUND:Healthcare associated infections are associated with indwelling devices. Yet, data regarding prevalence of indwelling devices in noncritically ill hospitalized patients remains scant. METHODS:Adult, noncritically ill patients on general care, telemetry, and surgical floors at our quaternary care hospital we...
journal_title：American journal of infection control
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journal_title：American journal of infection control
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journal_title：American journal of infection control
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journal_title：American journal of infection control
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journal_title：American journal of infection control
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更新日期：1993-04-01 00:00:00
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journal_title：American journal of infection control
pub_type： 杂志文章
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journal_title：American journal of infection control
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更新日期：2013-01-01 00:00:00
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journal_title：American journal of infection control
pub_type： 杂志文章
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更新日期：2020-03-01 00:00:00
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journal_title：American journal of infection control
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journal_title：American journal of infection control
pub_type： 杂志文章
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journal_title：American journal of infection control
pub_type： 杂志文章
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更新日期：2019-01-01 00:00:00
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journal_title：American journal of infection control
pub_type： 杂志文章
doi：10.1016/j.ajic.2014.05.001
更新日期：2014-10-01 00:00:00
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journal_title：American journal of infection control
pub_type： 杂志文章
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更新日期：1993-02-01 00:00:00
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journal_title：American journal of infection control
pub_type： 杂志文章
doi：10.1016/j.ajic.2007.11.007
更新日期：2008-09-01 00:00:00
