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Linking differential chromatin loops to transcriptional decisions.

Abstract：

:GATA-1 and GATA-2 control proliferation and differentiation of hematopoietic progenitor cells via transcriptional regulation. In this issue of Molecular Cell, Jing et al. (2008) demonstrate that GATA factor exchange on the Kit locus directs a transcriptional switch by reconfiguring chromatin loops.

journal_name

Mol Cell

journal_title

Molecular cell

authors

Apostolou E,Thanos D

doi

10.1016/j.molcel.2008.01.008

subject

Has Abstract

pub_date

2008-02-01 00:00:00

pages

154-6

issue

2

eissn

1097-2765

issn

1097-4164

pii

S1097-2765(08)00043-9

journal_volume

29

pub_type

评论,杂志文章

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