Abstract:
:The authors present a new algorithmic procedure for the analysis of brain images. This procedure is specifically designed to image the activity and functional organization of the brain. The authors' results are tested on data collected and previously analyzed with the technique known as in vivo optical imaging of intrinsic signals. The authors' procedure enhances the applicability of this technique and facilitates the extension of the underlying ideas to other imaging problems (e.g., functional MRI). The authors' thrust is two fold. First, they give a systematic method to control the blood vessel artifacts which typically reduce the dynamic range of the image. They propose a mathematical model for the vibrations in time of the veins and arteries and they design a new method for cleaning the images of the vessels with the highest time variations. This procedure is based on the analysis of the singularities of the images. The use of wavelet transform is of crucial importance in characterizing the singularities and reconstructing appropriate versions of the original images. The second important component of the authors' work is the analysis of the time evolution of the fine structure of the images. They show that, once the images have been cleaned of the blood vessel vibrations/variations, the principal component of the time evolutions of the signals is due to the functional activity following the stimuli. The part of the brain where this function takes place can be localized and delineated with precision.
journal_name
IEEE Trans Med Imagingjournal_title
IEEE transactions on medical imagingauthors
Carmona RA,Hwang WL,Frostig RDdoi
10.1109/42.414621subject
Has Abstractpub_date
1995-01-01 00:00:00pages
556-64issue
3eissn
0278-0062issn
1558-254Xjournal_volume
14pub_type
杂志文章abstract::Tomographic reconstruction from positron emission tomography (PET) data is an ill-posed problem that requires regularization. An attractive approach is to impose an l(1) -regularization constraint, which favors sparse solutions in the wavelet domain. This can be achieved quite efficiently thanks to the iterative algor...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.2008.923698
更新日期:2008-01-01 00:00:00
abstract::This paper presents a new variational method for the segmentation of a moving object against a still background, over a sequence of [two-dimensional or three-dimensional (3-D)] image frames. The method is illustrated in application to myocardial gated single photon emission computed tomography (SPECT) data, and incorp...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/42.932748
更新日期:2001-07-01 00:00:00
abstract::Psoriasis is a chronic inflammatory skin disease that affects over 3% of the population. Various methods are currently used to evaluate psoriasis severity and to monitor therapeutic response. The PASI system of scoring is widely used for evaluating psoriasis severity. It employs a visual analogue scale to score the th...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.2012.2236349
更新日期:2013-04-01 00:00:00
abstract::This paper describes a multimodality framework for computer-aided myocardial viability assessment based on neuro-fuzzy techniques. The proposed approach distinguishes two main levels: the modality-independent inference level and the modality-dependent application level. This two-level distinction releases the hard con...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/42.974925
更新日期:2001-12-01 00:00:00
abstract::Cell or nucleus detection is a fundamental task in microscopy image analysis and has recently achieved state-of-the-art performance by using deep neural networks. However, training supervised deep models such as convolutional neural networks (CNNs) usually requires sufficient annotated image data, which is prohibitive...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.2020.3042789
更新日期:2020-12-07 00:00:00
abstract::Two methods for recovering an image that has been degraded while being processed are presented. The restoration problem is formulated as a constrained optimization problem in which a measure of smoothness based on the second derivatives of the restored image is maximized subject to the constraint that noise energy is ...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/42.126904
更新日期:1992-01-01 00:00:00
abstract::It is well known that the inverse radon transform exists in two forms for odd and even dimension functions, respectively. This note shows that these formulas become zero when the dimension requirement is violated, which results in a simple unified formula for the inverse radon transform of arbitrary dimensions. ...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/42.476117
更新日期:1995-01-01 00:00:00
abstract::The quantitative analysis of magnetic resonance imaging (MRI) data has become increasingly important in both research and clinical studies aiming at human brain development, function, and pathology. Inevitably, the role of quantitative image analysis in the evaluation of drug therapy will increase, driven in part by r...
journal_title:IEEE transactions on medical imaging
pub_type: 临床试验,杂志文章
doi:10.1109/TMI.2002.806283
更新日期:2002-10-01 00:00:00
abstract::This editorial introduces the Special Issue on Simulation and Synthesis in Medical Imaging. In this editorial, we define so-far ambiguous terms of simulation and synthesis in medical imaging. We also briefly discuss the synergistic importance of mechanistic (hypothesis-driven) and phenomenological (data-driven) models...
journal_title:IEEE transactions on medical imaging
pub_type: 社论
doi:10.1109/TMI.2018.2800298
更新日期:2018-03-01 00:00:00
abstract::Cone beam X-ray luminescence computed tomography (CB-XLCT) is a promising imaging technique in studying the physiological and pathological processes in small animals. However, the dynamic bio-distributions of probes in small animal, especially in adjacent targets are still hard to be captured directly from dynamic CB-...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.2019.2917026
更新日期:2019-12-01 00:00:00
abstract::In this paper, we propose a new prostate computed tomography (CT) segmentation method for image guided radiation therapy. The main contributions of our method lie in the following aspects. 1) Instead of using voxel intensity information alone, patch-based representation in the discriminative feature space with logisti...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.2012.2230018
更新日期:2013-02-01 00:00:00
abstract::Although Blood Oxygenation Level Dependent (BOLD) functional MRI (fMRI) is widely used to examine brain function in adults, the need for general anesthesia limits its practical utility in infants and small children. Functional Near-Infrared Spectroscopy - Diffuse Optical Tomography (fNIRS-DOT) imaging promises to be a...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.2020.2990823
更新日期:2020-11-01 00:00:00
abstract::Reconstruction of white matter connectivity in the fetal brain from in utero diffusion-weighted magnetic resonance imaging (MRI) faces many challenges, including subject motion, small anatomical scale, and limited image resolution and signal. These issues are compounded by the need to track significant changes in stru...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.2019.2932681
更新日期:2020-03-01 00:00:00
abstract::Magnetic resonance imaging (MRI) on patients with implanted deep brain stimulators (DBSs) can be hazardous because of the antenna-effect of leads exposed to the incident radio-frequency field. This study evaluated electromagnetic field and specific absorption rate (SAR) changes as a function of lead resistivity on an ...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.2010.2040624
更新日期:2010-04-01 00:00:00
abstract::Bronchoscopy is a major step in lung cancer staging. To perform bronchoscopy, the physician uses a procedure plan, derived from a patient's 3D computed-tomography (CT) chest scan, to navigate the bronchoscope through the lung airways. Unfortunately, physicians vary greatly in their ability to perform bronchoscopy. As ...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.2013.2252361
更新日期:2013-08-01 00:00:00
abstract::An optical model for imaging the retina through cataracts has been developed. The images are treated as sample functions of stochastic processes. On the basis of the model a homomorphic Weiner filter can be designed that will optimally restore the cataractous image (in the mean-square-error sense). The design of the f...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/42.41493
更新日期:1989-01-01 00:00:00
abstract::Component averaging (CAV) was recently introduced by Censor, Gordon, and Gordon as a new iterative parallel technique suitable for large and sparse unstructured systems of linear equations. Based on earlier work of Byrne and Censor, it uses diagonal weighting matrices, with pixel-related weights determined by the spar...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/42.959302
更新日期:2001-10-01 00:00:00
abstract::This paper discusses image reconstruction with a tilted gantry in multislice computed tomography (CT) with helical (spiral) data acquisition. The reconstruction problem with gantry tilt is shown to be transformable into the problem of reconstructing a virtual object from multislice CT data with no gantry tilt, for whi...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.2004.829337
更新日期:2004-09-01 00:00:00
abstract::Image reconstruction in low-count PET is particularly challenging because gammas from natural radioactivity in Lu-based crystals cause high random fractions that lower the measurement signal-to-noise-ratio (SNR). In model-based image reconstruction (MBIR), using more iterations of an unregularized method may increase ...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.2020.2998480
更新日期:2020-11-01 00:00:00
abstract::We introduce a multi-region model for simultaneous segmentation of medical images. In contrast to many other models, geometric constraints such as inclusion and exclusion between the regions are enforced, which makes it possible to correctly segment different regions even if the intensity distributions are identical. ...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.2012.2218117
更新日期:2013-02-01 00:00:00
abstract::We present a new approach to anisotropic diffusion based on a multidirectional diffusion flux. The diffusion flux is decomposed in an orthogonal basis, effectively enabling enhancement of contours as well as diffusion along the contours. To this end, we have selected a three-dimensional basis that depicts the directio...
journal_title:IEEE transactions on medical imaging
pub_type: 信件
doi:10.1109/TMI.2002.806403
更新日期:2002-11-01 00:00:00
abstract::A novel splat feature classification method is presented with application to retinal hemorrhage detection in fundus images. Reliable detection of retinal hemorrhages is important in the development of automated screening systems which can be translated into practice. Under our supervised approach, retinal color images...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.2012.2227119
更新日期:2013-02-01 00:00:00
abstract::Optical Diffusion Tomography (ODT) is a modern non-invasive medical imaging modality which requires mathematical modelling of near-infrared light propagation in tissue. Solving the ODT forward problem equation accurately and efficiently is crucial. Typically, the forward problem is represented by a Diffusion PDE and i...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.2016.2641500
更新日期:2017-04-01 00:00:00
abstract::Tracking subcellular structures as well as viral structures displayed as 'particles' in fluorescence microscopy images yields quantitative information on the underlying dynamical processes. We have developed an approach for tracking multiple fluorescent particles based on probabilistic data association. The approach c...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.2014.2359541
更新日期:2015-02-01 00:00:00
abstract::It is well known that the energy dependence of X-ray attenuation can be used to characterize materials. Yet, even with energy discriminating photon counting X-ray detectors, it is still unclear how to best form energy dependent measurements for spectral imaging. Common ideas include binning photon counts based on thei...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.2010.2061862
更新日期:2011-01-01 00:00:00
abstract::Instrument detection, pose estimation, and tracking in surgical videos are an important vision component for computer-assisted interventions. While significant advances have been made in recent years, articulation detection is still a major challenge. In this paper, we propose a deep neural network for articulated mul...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.2017.2787672
更新日期:2018-05-01 00:00:00
abstract::Spectral computed tomography (CT) is a promising technique with the potential for improving lesion detection, tissue characterization, and material decomposition. In this paper, we are interested in kVp switching-based spectral CT that alternates distinct kVp X-ray transmissions during gantry rotation. This system can...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.2014.2380993
更新日期:2015-03-01 00:00:00
abstract::Small pulmonary nodules are a common radiographic finding that presents an important diagnostic challenge in contemporary medicine. While pulmonary nodules are the major radiographic indicator of lung cancer, they may also be signs of a variety of benign conditions. Measurement of nodule growth rate over time has been...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.2003.817785
更新日期:2003-10-01 00:00:00
abstract::It is known that when the maximum likelihood estimator (MLE) algorithm passes a certain point, it produces images that begin to deteriorate. We propose a quantitative criterion with a simple probabilistic interpretation that allows the user to stop the algorithm just before this effect begins. The MLE algorithm search...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.1987.4307849
更新日期:1987-01-01 00:00:00
abstract::We present the use of an entropy focus criterion to enable automatic focusing of motion corrupted magnetic resonance images. We demonstrate the principle using illustrative examples from cooperative volunteers. Our technique can determine unknown patient motion or use knowledge of motion from other measures as a start...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/42.650886
更新日期:1997-12-01 00:00:00