Space-time segmentation using level set active contours applied to myocardial gated SPECT.

Abstract:

:This paper presents a new variational method for the segmentation of a moving object against a still background, over a sequence of [two-dimensional or three-dimensional (3-D)] image frames. The method is illustrated in application to myocardial gated single photon emission computed tomography (SPECT) data, and incorporates a level set framework to handle topological changes while providing closed boundaries. The key innovation is the introduction of a geometrical constraint into the derivation of the Euler-Lagrange equations, such that the segmentation of each individual frame can be interpreted as a closed boundary of an object (an isolevel of a set of hyper-surfaces) while integrating information over the entire sequence. This results in the definition of an evolution velocity normal to the object boundary. Applying this method to 3-D myocardial gated SPECT sequences, the left ventricle endocardial and epicardial limits can be computed in each frame. This space-time segmentation method was tested on simulated and clinical 3-D myocardial gated SPECT sequences and the corresponding ejection fractions were computed.

journal_name

IEEE Trans Med Imaging

authors

Debreuve E,Barlaud M,Aubert G,Laurette I,Darcourt J

doi

10.1109/42.932748

subject

Has Abstract

pub_date

2001-07-01 00:00:00

pages

643-59

issue

7

eissn

0278-0062

issn

1558-254X

journal_volume

20

pub_type

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