Abstract：
:A novel image reconstruction algorithm has been developed and demonstrated for fluorescence-enhanced frequency-domain photon migration (FDPM) tomography from measurements of area illumination with modulated excitation light and area collection of emitted fluorescence light using a gain modulated image-intensified charge-coupled device (ICCD) camera. The image reconstruction problem was formulated as a nonlinear least-squares-type simple bounds constrained optimization problem based upon the penalty/modified barrier function (PMBF) method and the coupled diffusion equations. The simple bounds constraints are included in the objective function of the PMBF method and the gradient-based truncated Newton method with trust region is used to minimize the function for the large-scale problem (39919 unknowns, 2973 measurements). Three-dimensional (3-D) images of fluorescence absorption coefficients were reconstructed using the algorithm from experimental reflectance measurements under conditions of perfect and imperfect distribution of fluorophore within a single target. To our knowledge, this is the first time that targets have been reconstructed in three-dimensions from reflectance measurements with a clinically relevant phantom.
journal_name
IEEE Trans Med Imagingjournal_title
IEEE transactions on medical imagingauthors
Roy R,Thompson AB,Godavarty A,Sevick-Muraca EMdoi
10.1109/tmi.2004.839359subject
Has Abstractpub_date
2005-02-01 00:00:00pages
137-54issue
2eissn
0278-0062issn
1558-254Xjournal_volume
24pub_type
杂志文章abstract：:This paper presents a method to reconstruct moving objects from cone beam X-ray projections acquired during a single rotational run using a given motion vector field. The method is applicable to voxel driven cone-beam filtered back-projection reconstruction approaches. Here, a formulation based on the algorithm of Fel...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/tmi.2006.876147
更新日期：2006-07-01 00:00:00
abstract：:This paper describes the implementation of a novel and robust threshold energy calibration method for photon counting detectors using polychromatic X-ray tubes. Methods often used for such energy calibration may require re-orientation of the detector or introduce calibration errors that are flux and acquisition time-d...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2018.2875932
更新日期：2019-04-01 00:00:00
abstract：:In this paper, we formulate a reconstruction algorithm for an n-Pi acquisition, where n can be any positive odd integer. The algorithm is a generalization of the method presented in (Bontus et al. 2003). It is based on the results obtained by Katsevich (2004). For the algorithm, different sets of filter-lines have to ...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2005.850545
更新日期：2005-08-01 00:00:00
abstract：:Automatic and accurate classification of retinal optical coherence tomography (OCT) images is essential to assist ophthalmologist in the diagnosis and grading of macular diseases. Clinically, ophthalmologists usually diagnose macular diseases according to the structures of macular lesions, whose morphologies, size, an...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2019.2898414
更新日期：2019-08-01 00:00:00
abstract：:The National Library of Medicine (NLM) is developing a digital chest X-ray (CXR) screening system for deployment in resource constrained communities and developing countries worldwide with a focus on early detection of tuberculosis. A critical component in the computer-aided diagnosis of digital CXRs is the automatic ...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2013.2290491
更新日期：2014-02-01 00:00:00
abstract：:In this paper, we are interested in soft tissue differentiation by multiband images obtained from the High-Resolution Ultrasonic Transmission Tomography (HUTT) system using a spectral target detection method based on constrained energy minimization (CEM). We have developed a new tissue differentiation method (called "...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/tmi.2004.843179
更新日期：2005-03-01 00:00:00
abstract：:After a brief discussion of the algebraic reconstruction techniques (ART), we introduce the attenuation problem in positron emission tomography (PET). We anticipate that a generalization of ART, the so-called cyclic subgradient projection (CSP) method, may be useful for solving this problem. This, however, has not bee...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.1982.4307567
更新日期：1982-01-01 00:00:00
abstract：:The performance of a classifier is largely dependent on the size and representativeness of data used for its training. In circumstances where accumulation and/or labeling of training samples is difficult or expensive, such as medical applications, data augmentation can potentially be used to alleviate the limitations ...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2016.2640180
更新日期：2017-04-01 00:00:00
abstract：:The identification of bronchi on Computed Tomography (CT) images of the lungs provides valuable clinical information in patients with suspected airways diseases including bronchiectasis, emphysema, or constrictive obliterative bronchiolitis. The automated recognition of the airways is, therefore, an important part of ...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/42.952731
更新日期：2001-09-01 00:00:00
abstract：:Multisource cone-beam computed tomography (CT) is an attractive approach of choice for superior temporal resolution, which is critically important for cardiac imaging and contrast enhanced studies. In this paper, we present a filtered-backprojection (FBP) algorithm for triple-source helical cone-beam CT. The algorithm...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2008.2004817
更新日期：2009-03-01 00:00:00
abstract：:We present a new algorithm which merges discontinuities in 3-D images of tubular structures presenting undesirable gaps. The application of the proposed method is mainly associated to large 3-D images of microvascular networks. In order to recover the real network topology, we need to fill the gaps between the closest...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2007.913248
更新日期：2008-05-01 00:00:00
abstract：:Gastro-intestinal (GI) endoscopy is a widely used clinical procedure for screening and surveillance of digestive tract diseases ranging from Barrett's Oesophagus to oesophageal cancer. Current surveillance protocol consists of periodic endoscopic examinations performed in 3-4 month intervals including expert's visual ...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2011.2174252
更新日期：2012-03-01 00:00:00
abstract：:Computed ultrasound tomography in echo mode (CUTE) is a promising ultrasound (US) based multi-modal technique that allows to image the spatial distribution of speed of sound (SoS) inside tissue using hand-held pulse-echo US. It is based on measuring the phase shift of echoes when detected under varying steering angles...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2020.3029286
更新日期：2020-10-07 00:00:00
abstract：:Ultrasound molecular imaging (USMI) is accomplished by detecting microbubble (MB) contrast agents that have bound to specific biomarkers, and can be used for a variety of imaging applications, such as the early detection of cancer. USMI has been widely utilized in preclinical imaging in mice; however, USMI in humans c...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2017.2774814
更新日期：2018-01-01 00:00:00
abstract：:A new reconstruction method, coined MIRAGE, is presented for accurate, fast, and robust parameter mapping of multiple-echo gradient-echo (MEGE) imaging, the basis sequence of novel quantitative magnetic resonance imaging techniques such as water content and susceptibility mapping. Assuming that the temporal signal can...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2017.2771504
更新日期：2018-02-01 00:00:00
abstract：:In dynamic planar imaging, extraction of signals specific to structures is complicated by structures superposition. Due to overlapping, signals extraction with classic regions of interest (ROIs) methods suffers from inaccuracy, as extracted signals are a mixture of targeted signals. Partial volume effect raises the sa...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2017.2759661
更新日期：2018-01-01 00:00:00
abstract：:The problem of automatic quantification of brain tissue by utilizing single-valued (single echo) magnetic resonance imaging (MRI) brain scans is addressed. It is shown that this problem can be solved without classification or segmentation, a method that may be particularly useful in quantifying white matter lesions wh...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/42.241885
更新日期：1993-01-01 00:00:00
abstract：:We show that electrical impedance tomography (EIT) image reconstruction algorithms with regularization based on the total variation (TV) functional are suitable for in vivo imaging of physiological data. This reconstruction approach helps to preserve discontinuities in reconstructed profiles, such as step changes in e...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2009.2022540
更新日期：2010-01-01 00:00:00
abstract：:A three-dimensional reconstruction method which uses cone-beam data was implemented. Issues concerning implementation are investigated and discussed in detail. Computer simulations were used to determine the amount of image degradation occurring in each of the three steps that comprise the reconstruction method. In ad...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/42.141650
更新日期：1992-01-01 00:00:00
abstract：:With continuing improvements in spatial resolution of positron emission tomography (PET) scanners, small patient movements during PET imaging become a significant source of resolution degradation. This work develops and investigates a comprehensive formalism for accurate motion-compensated reconstruction which at the ...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2008.917248
更新日期：2008-08-01 00:00:00
abstract：:The hybrid magnetic resonance (MR)/X-ray suite (XMR) is a recently introduced imaging solution that provides new possibilities for guidance of cardiovascular catheterization procedures. We have previously described and validated a technique based on optical tracking to register MR and X-ray images obtained from the sl...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2005.856731
更新日期：2005-11-01 00:00:00
abstract：:Imaging intramyocardial vascular flows in real-time could strongly help to achieve better diagnostic of cardiovascular diseases. To date, no standard imaging modality allows describing accurately myocardial blood flow dynamics with good spatial and temporal resolution. We recently introduced a novel ultrasonic Doppler...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2012.2203316
更新日期：2012-08-01 00:00:00
abstract：:In waveform design for magnetic resonance applications, periodic continuous-wave excitation offers potential advantages that remain largely unexplored because of a lack of understanding of the Bloch equation with periodic continuous-wave excitations. Using harmonic balancing techniques the steady state solutions of th...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2015.2423313
更新日期：2015-10-01 00:00:00
abstract：:Functional magnetic resonance imaging (fMRI) provides a window on the human brain at work. Spontaneous brain activity measured during resting-state has already provided many insights into brain function. In particular, recent interest in dynamic interactions between brain regions has increased the need for more advanc...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2017.2755369
更新日期：2018-01-01 00:00:00
abstract：:To reconstruct electrical activity in the heart from body-surface electrocardiograms (ECGs) is an ill-posed inverse problem. Electrophysiological models have been found effective in regularizing these inverse problems by incorporating a priori knowledge about how the electrical potential in the heart propagates over t...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2019.2906600
更新日期：2019-11-01 00:00:00
abstract：:Alzheimer's disease (AD) is a serious neurodegenerative condition that affects millions of individuals across the world. As the average age of individuals in the United States and the world increases, the prevalence of AD will continue to grow. To address this public health problem, the research community has develope...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2019.2958943
更新日期：2020-06-01 00:00:00
abstract：:A rule-based, low-level segmentation system that can automatically identify the space occupied by different structures of the brain by magnetic resonance imaging (MRI) is described. Given three-dimensional image data as a stack of slices, it can extract brain parenchyma, cerebro-spinal fluid, and high-intensity abnorm...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/42.57771
更新日期：1990-01-01 00:00:00
abstract：:With its single cell sensitivity over volumes as large as or larger than a mouse, cryo-imaging enables imaging of stem cell biodistribution, homing, engraftment, and molecular mechanisms. We developed and evaluated a highly automated software tool to detect fluorescently labeled stem cells within very large ( ∼ 200 GB...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2015.2497285
更新日期：2016-03-01 00:00:00
abstract：:A common challenge when performing surface-based registration of images is ensuring that the surfaces accurately represent consistent anatomical boundaries. Image segmentation may be difficult in some regions due to either poor contrast, low slice resolution, or tissue ambiguities. To address this, we present a novel ...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2015.2443978
更新日期：2015-12-01 00:00:00
abstract：:A big challenge in sensorless image-based ultrasound tracking is in the out-of-plane motion estimation. The correlation value of a specific model of speckle known as fully developed speckle (FDS) can be used to estimate the out-of-plane displacement. In real tissue, this kind of pattern is rare and the deviation of sp...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2013.2283969
更新日期：2014-01-01 00:00:00
