In vivo impedance imaging with total variation regularization.

Abstract:

:We show that electrical impedance tomography (EIT) image reconstruction algorithms with regularization based on the total variation (TV) functional are suitable for in vivo imaging of physiological data. This reconstruction approach helps to preserve discontinuities in reconstructed profiles, such as step changes in electrical properties at interorgan boundaries, which are typically smoothed by traditional reconstruction algorithms. The use of the TV functional for regularization leads to the minimization of a nondifferentiable objective function in the inverse formulation. This cannot be efficiently solved with traditional optimization techniques such as the Newton method. We explore two implementations methods for regularization with the TV functional: the lagged diffusivity method and the primal dual-interior point method (PD-IPM). First we clarify the implementation details of these algorithms for EIT reconstruction. Next, we analyze the performance of these algorithms on noisy simulated data. Finally, we show reconstructed EIT images of in vivo data for ventilation and gastric emptying studies. In comparison to traditional quadratic regularization, TV regularization shows improved ability to reconstruct sharp contrasts.

journal_name

IEEE Trans Med Imaging

authors

Borsic A,Graham BM,Adler A,Lionheart WR

doi

10.1109/TMI.2009.2022540

subject

Has Abstract

pub_date

2010-01-01 00:00:00

pages

44-54

issue

1

eissn

0278-0062

issn

1558-254X

journal_volume

29

pub_type

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