Abstract：
:Optoacoustic (photoacoustic) dermoscopy offers two principal advantages over conventional optical imaging applied in dermatology. First, it yields high-resolution cross-sectional images of the skin at depths not accessible to other non-invasive optical imaging methods. Second, by resolving absorption spectra at multiple wavelengths, it enables label-free 3D visualization of morphological and functional features. However, the relation of pulse energy to generated bandwidth and imaging depth remains poorly defined. In this paper, we apply computer models to investigate the optoacoustic frequency response generated by simulated skin. We relate our simulation results to experimental measurements of the detection bandwidth as a function of optical excitation energy in phantoms and human skin. Using raster-scan optoacoustic mesoscopy, we further compare the performance of two broadband ultrasonic detectors (a bandwidth of 20-180 and 10-90MHz) in acquiring optoacoustic readouts. Based on the findings of this paper, we propose energy ranges required for skin imaging with considerations of laser safety standards.
journal_name
IEEE Trans Med Imagingjournal_title
IEEE transactions on medical imagingauthors
Schwarz M,Soliman D,Omar M,Buehler A,Ovsepian SV,Aguirre J,Ntziachristos Vdoi
10.1109/TMI.2017.2664142subject
Has Abstractpub_date
2017-06-01 00:00:00pages
1287-1296issue
6eissn
0278-0062issn
1558-254Xjournal_volume
36pub_type
杂志文章abstract：:We have calculated the aperture function of a positron computed tomograph (PCT) with computer simulation, and evaluated the axial resolution of a multislice PCT, Positologica III, both theoretically and experimentally. The axial point spread function (PSF) was approximately a triangle at or near the center of the fiel...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.1985.4307692
更新日期：1985-01-01 00:00:00
abstract：:Complete projection (360 degrees ) free-space fluorescence tomography of opaque media is poised to enable 3-D imaging through entire small animals in vivo with improved depth resolution compared to 360 degrees -projection fiber-based systems or limited-view angle systems. This approach can lead to a new generation of ...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2007.904662
更新日期：2008-02-01 00:00:00
abstract：:Convolutional neural networks (CNNs) have recently been used in biomedical imaging applications with great success. In this paper, we investigated the classi?cation performance of CNN models on diffusion weighted imaging (DWI) streamlines de?ned by functional MRI (fMRI) and electrical stimulation mapping (ESM). To lea...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2019.2902073
更新日期：2019-02-27 00:00:00
abstract：:Wireless capsule endoscopy has opened a new era by enabling remote diagnostic assessment of the gastrointestinal tract in a painless procedure. Video capsule endoscopy is currently commercially available worldwide. However, it is limited to visualization of superficial tissue. Ultrasound (US) imaging is a complementar...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2017.2699973
更新日期：2017-09-01 00:00:00
abstract：:The classification of 3 common breast lesions, fibroadenomas, cysts, and cancers, was achieved using computerized image analysis of tumor shape in conjunction with patient age. The process involved the digitization of 69 mammographic images using a video camera and a commercial frame grabber on a PC-based computer sys...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/42.251116
更新日期：1993-01-01 00:00:00
abstract：:A method for measuring the spatial concentration of specific categories of vessels in a vascular network consisting of vessels of several diameters, lengths, and orientations is demonstrated. It is shown that a combination of the mathematical morphology operation, opening, with a linear rotating structuring element (R...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/42.241865
更新日期：1993-01-01 00:00:00
abstract：:Accurate medical image segmentation is essential for diagnosis and treatment planning of diseases. Convolutional Neural Networks (CNNs) have achieved state-of-the-art performance for automatic medical image segmentation. However, they are still challenged by complicated conditions where the segmentation target has lar...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2020.3035253
更新日期：2020-11-02 00:00:00
abstract：:Many segmentation methods for thoracic volume data require manual input in the form of a seed point, initial contour, volume of interest etc. The aim of the work presented here is to further automate this segmentation initialization step. In this paper an anatomical modeling and matching method is proposed to coarsely...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/42.764893
更新日期：1999-03-01 00:00:00
abstract：:Peripheral Nerve Stimulation (PNS) limits the acquisition rate of Magnetic Resonance Imaging data for fast sequences employing powerful gradient systems. The PNS characteristics are currently assessed after the coil design phase in experimental stimulation studies using constructed coil prototypes. This makes it diffi...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2020.3023329
更新日期：2021-01-01 00:00:00
abstract：:In this paper, we propose a new prostate computed tomography (CT) segmentation method for image guided radiation therapy. The main contributions of our method lie in the following aspects. 1) Instead of using voxel intensity information alone, patch-based representation in the discriminative feature space with logisti...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2012.2230018
更新日期：2013-02-01 00:00:00
abstract：:In this paper, discrepancies and reference inaccuracies in the paper (Grana et al., 2003) are pointed out. Specifically, it is demonstrated that the definitions of "lesion gradient" and "skin lesion gradient," widely used in a number of medical papers on computer analysis of pigmented skin lesions, are unambiguous, an...
journal_title：IEEE transactions on medical imaging
pub_type： 评论,信件
doi：10.1109/tmi.2006.884205
更新日期：2006-12-01 00:00:00
abstract：:A novel approach to correcting for intensity nonuniformity in magnetic resonance (MR) data is described that achieves high performance without requiring a model of the tissue classes present. The method has the advantage that it can be applied at an early stage in an automated data analysis, before a tissue model is a...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/42.668698
更新日期：1998-02-01 00:00:00
abstract：:This paper presents a virtual tagging framework for measuring, as well as visualising, myocardial deformation using magnetic resonance (MR) velocity imaging. Tagging grids are allocated artificially according to the deformation gradient with varying shapes and densities. The control points are then deformed such that ...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2002.804429
更新日期：2002-09-01 00:00:00
abstract：:This paper addresses the implementation of image processing and computer vision techniques to automate tracer flow extraction in images obtained by the photochromic dye technique. This task is important in modeled arterial blood flow studies. Currently, it is performed via manual application of B-spline curve fitting....
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/42.585762
更新日期：1997-06-01 00:00:00
abstract：PURPOSE:Demonstration of a technique for three-dimensional (3-D) assessment of tracheal-stenoses, regarding site, length and degree, based on spiral computed tomography (S-CT). PATIENTS AND METHODS:S-CT scanning and automated segmentation of the laryngo-tracheal tract (LTT) was followed by the extraction of the LTT me...
journal_title：IEEE transactions on medical imaging
pub_type： 临床试验,杂志文章
doi：10.1109/42.996344
更新日期：2002-03-01 00:00:00
abstract：:Imaging intramyocardial vascular flows in real-time could strongly help to achieve better diagnostic of cardiovascular diseases. To date, no standard imaging modality allows describing accurately myocardial blood flow dynamics with good spatial and temporal resolution. We recently introduced a novel ultrasonic Doppler...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2012.2203316
更新日期：2012-08-01 00:00:00
abstract：:In magnetic resonance imaging (MRI), it is well-known that patient motion plays a significant role in the degradation of image quality. Although the case of translational in-plane motion (x-y-motion) has been studied by several researchers, the effect of rigid, translational out-of-plane motion (z-motion) has not yet ...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/42.414611
更新日期：1995-01-01 00:00:00
abstract：:Our primary motivator is the need for screening HIV+ populations in resource-constrained regions for exposure to Tuberculosis, using posteroanterior chest radiographs (CXRs). The proposed method is motivated by the observation that radiological examinations routinely conduct bilateral comparisons of the lung field. In...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2017.2775636
更新日期：2018-05-01 00:00:00
abstract：:Transmembrane voltage-sensitive fluorescent dyes are used to study electrical activity in hearts. Green and red fluorescence emissions from di-4-ANEPPS excited with 488 nm light indicate both transmembrane voltage changes and heart movement. We have previously shown that the ratio, green fluorescence divided by red fl...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2005.861019
更新日期：2006-01-01 00:00:00
abstract：:Photon counting computed tomography (PCCT) has the ability to identify individual photons, resulting in quantitative material identification. Meanwhile, several technical challenges still exist in current PCCT imaging systems, including increased noise and suboptimal bin selection. These nonideal effects can substanti...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2020.3001616
更新日期：2020-11-01 00:00:00
abstract：:Adolescence is a transitional period between the childhood and adulthood with physical changes, as well as increasing emotional development. Studies have shown that the emotional sensitivity is related to a second period of rapid brain growth. However, there is little focus on the trend of brain development during thi...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2019.2926667
更新日期：2020-02-01 00:00:00
abstract：:A novel image reconstruction algorithm has been developed and demonstrated for fluorescence-enhanced frequency-domain photon migration (FDPM) tomography from measurements of area illumination with modulated excitation light and area collection of emitted fluorescence light using a gain modulated image-intensified char...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/tmi.2004.839359
更新日期：2005-02-01 00:00:00
abstract：:Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) of the breast has become an invaluable tool in the clinical work-up of patients suspected of having breast carcinoma. The purpose of this study is to introduce novel features extracted from the kinetics of contrast agent uptake imaged by a short (100 s) vi...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2013.2281984
更新日期：2014-02-01 00:00:00
abstract：:Functional magnetic resonance images (fMRI's) provide high-resolution datasets which allow researchers to obtain accurate delineation and sensitive detection of activation areas involved in cognitive processes. To preserve the resolution of this noninvasive technique, refined methods are required in the analysis of th...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/42.746636
更新日期：1998-12-01 00:00:00
abstract：:The feasibility of ultrasonic Nakagami imaging to evaluate thermal lesions by high-intensity focused ultrasound and microwave ablation was explored in ex vivo and in vivo liver models. Dynamic changes of the ultrasonic Nakagami parameter in thermal lesions were calculated, and ultrasonic B-mode and Nakagami images wer...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2018.2829934
更新日期：2018-07-01 00:00:00
abstract：:A special-purpose hardware architecture is proposed to implement the expectation-maximization algorithm to compute, in clinically useful times, the maximum-likelihood estimate of a radionuclide distribution for a positron-emission tomogram from time-of-flight measurements. Two-dimensional convolutions required for for...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/42.14510
更新日期：1988-01-01 00:00:00
abstract：:Tracking pylorus in ultrasonic image sequences is an important step in the analysis of duodenogastric reflux (DGR). We propose a joint prediction and segmentation method (JPS) which combines optical flow with active contour to track pylorus. The goal of the proposed method is to improve the pyloric tracking accuracy b...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2012.2183884
更新日期：2012-03-01 00:00:00
abstract：:Over the years, medical image tracking has gained considerable attention from both medical and research communities due to its widespread utility in a multitude of clinical applications, from functional assessment during diagnosis and therapy planning to structure tracking or image fusion during image-guided intervent...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2018.2840820
更新日期：2018-11-01 00:00:00
abstract：:A direct (noniterative) reconstruction algorithm for electrical impedance tomography in the two-dimensional (2-D), cross-sectional geometry is reviewed. New results of a reconstruction of a numerically simulated phantom chest are presented. The algorithm is based on the mathematical uniqueness proof by A. I. Nachman [...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2002.800574
更新日期：2002-06-01 00:00:00
abstract：:Given that heart disease can cause abnormal motion dynamics over the cardiac cycle, understanding and quantifying cardiac motion can provide insight for clinicians to aid with diagnosis, therapy planning, and determining prognosis. The goal of this paper is to extract population-specific motion patterns from 3D displa...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2015.2405579
更新日期：2015-07-01 00:00:00
