Abstract：
:Deep learning is becoming an indispensable tool for various tasks in science and engineering. A critical step in constructing a reliable deep learning model is the selection of a loss function, which measures the discrepancy between the network prediction and the ground truth. While a variety of loss functions have been proposed in the literature, a truly optimal loss function that maximally utilizes the capacity of neural networks for deep learning-based decision-making has yet to be established. Here, we devise a generalized loss function with functional parameters determined adaptively during model training to provide a versatile framework for optimal neural network-based decision-making in small target segmentation. The method is showcased by more accurate detection and segmentation of lung and liver cancer tumors as compared with the current state-of-the-art. The proposed formalism opens new opportunities for numerous practical applications such as disease diagnosis, treatment planning, and prognosis.
journal_name
IEEE Trans Med Imagingjournal_title
IEEE transactions on medical imagingauthors
Seo H,Bassenne M,Xing Ldoi
10.1109/TMI.2020.3031913subject
Has Abstractpub_date
2020-10-19 00:00:00eissn
0278-0062issn
1558-254Xjournal_volume
PPpub_type
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