Testicular cancer in twins: a meta-analysis.

abstract：:The primary aim of this study was to investigate if the expression of the DNA damage identifying protein DNA-PKcs known to be involved in DNA repair after treatment with ionising radiation can be used as a predictive marker for radiotherapy (RT) response in cervical cancer. Formalin-fixed primary tumour biopsies from ...

journal_title：British journal of cancer

authors： Beskow C,Kanter L,Holgersson A,Nilsson B,Frankendal B,Avall-Lundqvist E,Lewensohn R

更新日期：2006-06-05 00:00:00

abstract：:Clear cell sarcoma of tendons and aponeuroses (malignant melanoma of soft parts) and conventional malignant melanoma may demonstrate significant morphologic overlap at the light microscopic and ultrastructural level. Consequently, the clinically relevant distinction between primary clear cell sarcoma and metastatic me...

journal_title：British journal of cancer

authors： Langezaal SM,Graadt van Roggen JF,Cleton-Jansen AM,Baelde JJ,Hogendoorn PC

更新日期：2001-02-01 00:00:00

abstract：:In the search for effective chemotherapy regimens which can be used in multimodality treatment programmes for patients with cancer of the oesophagus, we conducted a phase II trial to determine the activity and toxicity of the combination of cisplatin and etoposide in patients with advanced squamous cell carcinoma of t...

journal_title：British journal of cancer

authors： Kok TC,Van der Gaast A,Dees J,Eykenboom WM,Van Overhagen H,Stoter G,Tilanus HW,Splinter TA

更新日期：1996-09-01 00:00:00

abstract：:Our objective was to determine whether oral etoposide and cisplatin combination (EoP) is superior to paclitaxel in the treatment of advanced breast cancer (ABC) patients pretreated with anthracyclines. From December 1997 to August 2003, 201 patients were randomised, 100 to EoP and 101 to paclitaxel arms. Four patients...

journal_title：British journal of cancer

authors： Icli F,Akbulut H,Uner A,Yalcin B,Baltali E,Altinbas M,Coşkun S,Komurcu S,Erkisi M,Demirkazik A,Senler FC,Sencan O,Büyükcelik A,Boruban C,Onur H,Zengin N,Sak SD

更新日期：2005-02-28 00:00:00

abstract：BACKGROUND:Recent studies suggest that older patients in the United Kingdom are not benefiting as much from improvements in cancer treatments as their younger counterparts. We investigate whether this might be partly due to differential referral rates using ovarian cancer as an example. METHODS:From the General Practi...

journal_title：British journal of cancer

authors： Tate AR,Nicholson A,Cassell JA

更新日期：2010-03-16 00:00:00

abstract：BACKGROUND:When tumour tissue is unavailable, cell-free DNA (cfDNA)can serve as a surrogate for genetic analyses. Because mutated alleles in cfDNA are usually below 1%, next-generation sequencing (NGS)must be narrowed to target only clinically relevant genes. In this proof-of-concept study, we developed a panel to use ...

journal_title：British journal of cancer

authors： Malapelle U,Mayo de-Las-Casas C,Rocco D,Garzon M,Pisapia P,Jordana-Ariza N,Russo M,Sgariglia R,De Luca C,Pepe F,Martinez-Bueno A,Morales-Espinosa D,González-Cao M,Karachaliou N,Viteri Ramirez S,Bellevicine C,Molina-Vila M

更新日期：2017-03-14 00:00:00

abstract：:Eleven human bladder carcinomata of different degrees of differentiation were implanted in mice immunosuppressed by thymectomy, anti-thymocyte serum and x-rays. Seven carcinomata grew well and one poorly and 3 produced mainly fibrous nodules in the mice. Normal human bladder tissues were grown from 4 other patients. T...

journal_title：British journal of cancer

authors： Kelly JF,Snell ME,Berenbaum MC

更新日期：1975-02-01 00:00:00

abstract：:Pulmonary metastasectomy is widely and increasingly practiced in the belief that this intervention can cure patients with colorectal cancer, and that without it few survive 5 years. No good evidence exists supporting such convictions, indeed recent trial results challenge them. What evidence underpins this acceptance ...

journal_title：British journal of cancer

authors： Macbeth F,Fallowfield L

更新日期：2020-08-01 00:00:00

abstract：:Collagen breakdown, and thus bone resorption, can now be assessed by measuring the urinary excretion of the collagen crosslinks, pyridinoline (Pyd) and deoxypyridinoline (Dpd). In a pilot study we measured Pyd and Dpd in 20 patients with breast cancer, ten with known bone metastases and ten with no recognised metastas...

journal_title：British journal of cancer

authors： Paterson CR,Robins SP,Horobin JM,Preece PE,Cuschieri A

更新日期：1991-11-01 00:00:00

abstract：:Electrochemotherapy is an anti-tumour treatment that utilizes locally delivered electric pulses to increase cytotoxicity of chemotherapeutic drugs. The aim of our study was to determine whether anti-tumour effectiveness of electrochemotherapy with cisplatin is a consequence of increased plasma membrane permeability ca...

journal_title：British journal of cancer

authors： Cemazar M,Miklavcic D,Scancar J,Dolzan V,Golouh R,Sersa G

更新日期：1999-03-01 00:00:00

abstract：:Women referred to a familial breast cancer clinic completed questionnaires before and after counselling and at annual follow-up to assess their risk estimate and psychological characteristics. The aims were to determine whether those who attended the clinic overestimated their risk or were highly anxious and whether c...

journal_title：British journal of cancer

authors： Cull A,Anderson ED,Campbell S,Mackay J,Smyth E,Steel M

更新日期：1999-02-01 00:00:00

abstract：:Recombinant single-chain fragments (scFv) of the murine anti-MUC1 monoclonal antibody C595 have been produced using the original hybridoma cells as a source of variable heavy (V(H))- and variable light (V(L))-chain-encoding antibody genes. The use of the polymerase chain reaction (PCR), bacteriophage (phage) display t...

journal_title：British journal of cancer

authors： Denton G,Sekowski M,Spencer DI,Hughes OD,Murray A,Denley H,Tendler SJ,Price MR

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND:The urokinase plasminogen activator (uPA) system is one of the best-investigated protease systems, both under physiological and pathological conditions, including various types of cancer. However, effects of co-expression of members of the uPA system in soft-tissue sarcoma (STS) patients at the protein level...

journal_title：British journal of cancer

authors： Taubert H,Würl P,Greither T,Kappler M,Bache M,Lautenschläger C,Füssel S,Meye A,Eckert AW,Holzhausen HJ,Magdolen V,Kotzsch M

更新日期：2010-02-16 00:00:00

abstract：BACKGROUND:The germline BRCA2 mutation is associated with increased prostate cancer (PrCa) risk. We have assessed survival in young PrCa cases with a germline mutation in BRCA2 and investigated loss of heterozygosity at BRCA2 in their tumours. METHODS:Two cohorts were compared: one was a group with young-onset PrCa, t...

journal_title：British journal of cancer

authors： Edwards SM,Evans DG,Hope Q,Norman AR,Barbachano Y,Bullock S,Kote-Jarai Z,Meitz J,Falconer A,Osin P,Fisher C,Guy M,Jhavar SG,Hall AL,O'Brien LT,Gehr-Swain BN,Wilkinson RA,Forrest MS,Dearnaley DP,Ardern-Jones AT,Pag

更新日期：2010-09-07 00:00:00

abstract：:Immunoglobulins (Ig) and some complement components (C) were quantified in sera from patients with gastric carcinoma before surgery and at regular intervals during a 5-year follow-up. The preoperative concentrations of C1-INH and C4 were higher (P < 0.0005 and P < 0.005) and IgG lower (P < 0.0005) in 50 patients with ...

journal_title：British journal of cancer

authors： Janssen CW Jr,Lie RT,Bassøe CF,Maartmann-Moe H,Matre R

更新日期：1992-11-01 00:00:00

abstract：:Chlamydia pneumoniae, Chlamydia trachomatis and Chlamydia psittaci were detected at low frequencies (<20%) among 69 pulmonary mucosa-associated lymphoid tissue (MALT) lymphomas, 30 other lymphoproliferative disorders (LPD) and 44 non-LPD. The incidence of individual Chlamydiae was generally higher in MALT lymphoma tha...

journal_title：British journal of cancer

authors： Chanudet E,Adam P,Nicholson AG,Wotherspoon AC,Ranaldi R,Goteri G,Pileri SA,Ye H,Müller-Hermelink HK,Du MQ

更新日期：2007-10-08 00:00:00

abstract：:Fifty patients affected by histologically confirmed gastrointestinal tract cancer (GTC) were treated with oral tegafur (TG) 1,000 mg m-2 p.o. on days 1-14 repeated after a 14 day interval. Out of 42 evaluable patients seven patients had a partial response (PR. 17%) with a median duration of 20.5 weeks, three had a min...

journal_title：British journal of cancer

authors： Palmeri S,Gebbia V,Russo A,Armata MG,Gebbia N,Rausa L

更新日期：1990-03-01 00:00:00

abstract：:We investigated breast cancer incidence in migrants in the Netherlands in 1988-1998. The standardised incidence ratio for breast cancer in Northwest-Netherlands was statistically significantly reduced for women born in Surinam (0.56), Turkey (0.29) and Morocco (0.22). The proportion of women with advanced stages (III ...

journal_title：British journal of cancer

authors： Visser O,van der Kooy K,van Peppen AM,Ory FG,van Leeuwen FE

更新日期：2004-06-01 00:00:00

abstract：:The mechanism of down-regulation of c-myc RNA associated with androgen-induced suppression of the transformed phenotype in the human prostate carcinoma cell line LNCaP was investigated. The synthetic androgen mibolerone (7 alpha-17 alpha-Dimethyl-19-nortestosterone) reversibly inhibits the proliferation of LNCaP cells...

journal_title：British journal of cancer

authors： Wolf DA,Kohlhuber F,Schulz P,Fittler F,Eick D

更新日期：1992-03-01 00:00:00

abstract：:We analysed antibodies specific for human p53 in sera from primary breast cancer patients using three different immunoassays and we related these results to the p53 level in tumour tissue detected by immunohistochemistry. Only 44% (11/25) of apparently enzyme-linked immunosorbent assay (ELISA)-positive sera were from ...

journal_title：British journal of cancer

authors： Vojtesek B,Kovarik J,Dolezalova H,Nenutil R,Havlis P,Brentani RR,Lane DP

更新日期：1995-06-01 00:00:00

abstract：:Intrapleurally injected cells of an ascitic rat tumour produced intrapleural effusions and solid pleural deposits. BCG, or its methanol extraction residue (MER) injected into the pleural space, suppressed tumour development and prolonged survival. Treatment was effective if given a few days before or after tumour inje...

journal_title：British journal of cancer

authors： Pimm MV,Hopper DG,Baldwin RW

更新日期：1976-10-01 00:00:00

abstract：:The objective of the study was to evaluate the effect of neoadjuvant chemotherapy on the survival of patients with oropharyngeal cancer. Patients with a squamous cell carcinoma of the oropharynx for whom curative radiotherapy or surgery was considered feasible were entered in a multicentric randomized trial comparing ...

journal_title：British journal of cancer

authors： Domenge C,Hill C,Lefebvre JL,De Raucourt D,Rhein B,Wibault P,Marandas P,Coche-Dequeant B,Stromboni-Luboinski M,Sancho-Garnier H,Luboinski B,French Groupe d'Etude des Tumeurs de la Tête et du Cou (GETTEC).

更新日期：2000-12-01 00:00:00

abstract：:Early detection of relapse has been advocated to improve survival in children with recurrent medulloblastoma. However, the prognostic factors and the longer term outcome of these patients remains unclear. Pattern of recurrences were analysed in three consecutive protocols of the Société Française d'Oncologie Pédiatriq...

journal_title：British journal of cancer

authors： Bouffet E,Doz F,Demaille MC,Tron P,Roche H,Plantaz D,Thyss A,Stephan JL,Lejars O,Sariban E,Buclon M,Zücker JM,Brunat-Mentigny M,Bernard JL,Gentet JC

更新日期：1998-04-01 00:00:00

abstract：:Breast cancer is the second most common cancer among women in Madras and southern India after cervix cancer. The Madras Metropolitan Tumour Registry (MMTR), a population-based cancer registry, collects data on the outcome of cancer diagnosis by both active and passive methods. A total of 2080 cases of invasive female ...

journal_title：British journal of cancer

authors： Gajalakshmi CK,Shanta V,Swaminathan R,Sankaranarayanan R,Black RJ

更新日期：1997-01-01 00:00:00

abstract：:Aminoglutethimide without glucocorticoid has been shown to be a clinically effective treatment for postmenopausal breast cancer in low dosage (250 mg day-1). The mechanism of action of this approach is thought to be the inhibition of peripheral aromatase, the enzyme which converts androstenedione to oestrone. The acti...

journal_title：British journal of cancer

authors： Dowsett M,Santner SJ,Santen RJ,Jeffcoate SL,Smith IE

更新日期：1985-07-01 00:00:00

abstract：:Monoclonal antibody MUC 2-63 recognises neurogenic tumours and has been used successfully for radioimaging human malignant gliomas. We now show that the MUC 2-63 antigen has the same tissue distribution and molecular weight range as the CD44 antigen and confirm the identity of these two molecules in blocking studies u...

journal_title：British journal of cancer

authors： Romeijn P,Lenthall R,Stavrou D,Melcher D,Ladyman H,Ritter MA

更新日期：1994-11-01 00:00:00

abstract：:I have studied the effects on growth of two tumours in mice and on host toxicity, of combining Misonidazole (MISO) or Metronidazole (METRO) with Methotrexate (MTX)-5-fluorouracil (FU) or Adriamycin (ADR). The nitroimidazoles alone had no effect on the growth of either tumour, but MISO (1 mg/g) led to a small increase ...

journal_title：British journal of cancer

authors： Tannock IF

更新日期：1980-12-01 00:00:00

abstract：BACKGROUND:Little is known about the effect of participating in a colorectal cancer (CRC) screening programme on quality of life (QOL), neither for participants with a negative nor for those with a positive test result. These findings, however, are important to evaluate the impact of CRC screening. METHODS:Participant...

journal_title：British journal of cancer

authors： Kapidzic A,Korfage IJ,van Dam L,van Roon AH,Reijerink JC,Zauber AG,van Ballegooijen M,Kuipers EJ,van Leerdam ME

更新日期：2012-10-09 00:00:00

abstract：BACKGROUND:Germline mutations within DNA-repair genes are implicated in susceptibility to multiple forms of cancer. For prostate cancer (PrCa), rare mutations in BRCA2 and BRCA1 give rise to moderately elevated risk, whereas two of B100 common, low-penetrance PrCa susceptibility variants identified so far by genome-wid...

journal_title：British journal of cancer

authors： Saunders EJ,Dadaev T,Leongamornlert DA,Al Olama AA,Benlloch S,Giles GG,Wiklund F,Gronberg H,Haiman CA,Schleutker J,Nordestgaard BG,Travis RC,Neal D,Pasayan N,Khaw KT,Stanford JL,Blot WJ,Thibodeau SN,Maier C,Kibel AS

更新日期：2016-04-12 00:00:00

abstract：:Loss of the short arm of chromosome 1 is a hallmark of oligodendroglial tumours (OTs). Deletion mapping studies in OTs have revealed multiple commonly deleted regions on chromosome 1p, suggesting that there are more than one tumour suppressor gene. To map critical deletion regions on 1p, a series of 25 OTs were examin...

journal_title：British journal of cancer

authors： Dong Z,Pang JS,Ng MH,Poon WS,Zhou L,Ng HK

更新日期：2004-09-13 00:00:00