Erectile dysfunction as the presenting symptom of a pheochromocytoma.

Abstract:

:We report the case of a 59-year-old man with a pheochromocytoma in which erectile dysfunction was the main symptom. Erectile function was related to the amount of noradrenaline secreted by the tumor, as was determined when recurrence of the malignancy was diagnosed twice. Erectile function could be restored by lowering the level of noradrenaline excretion, either by removal of the noradrenaline-producing tumor or by treatment with doxazosin. By stimulating alpha-1-adrenoceptors, high levels of noradrenaline are likely to result in excessive contraction of the corpus cavernosum and penile vessels and, thereby, cause erectile dysfunction.

journal_name

Eur J Intern Med

authors

van den Berge K,van Guldener C,van Wijngaarden P

doi

10.1016/j.ejim.2007.02.027

subject

Has Abstract

pub_date

2007-12-01 00:00:00

pages

593-4

issue

8

eissn

0953-6205

issn

1879-0828

pii

S0953-6205(07)00153-7

journal_volume

18

pub_type

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