Abstract：
:Numerous epidemiological studies have shown an inverse correlation between moderate consumption of alcoholic drinks and the risk of coronary heart disease. Wine, especially red wine, may be more favorable in this respect than beer or spirits because of its high content of flavonoids. These polyphenols originate from the skins, seeds, and vine stems of the grapes while some are formed during the process of vinification. In nature they exhibit a wide range of biological effects as antioxidants, antimicrobials, and modulators of various enzyme systems. Potential beneficial effects for humans have been demonstrated in experimental studies and include influences on the oxidation of LDL-cholesterol, on platelet aggregation, and on prostaglandin and nitric oxide metabolism. However, most of these studies concern semi in vivo experiments and research in animal models; data from human intervention trials are scarce. Furthermore, little is known about the absorption, bioavailability, and bioactivity of most of these compounds because of difficulties in reliable quantification in biological fluids. Until these issues are well addressed, and despite the enthusiasm and faith of many believers, evidence-based medicine justifies a critical attitude towards the application of these compounds outside the context of scientific research. Yet, there is no need to deny their potential, nor should we close our eyes to the blessings of the grape.
journal_name
Eur J Intern Medjournal_title
European journal of internal medicineauthors
van de Wiel A,van Golde PH,Hart HCdoi
10.1016/s0953-6205(01)00170-4subject
Has Abstractpub_date
2001-12-01 00:00:00pages
484-9issue
6eissn
0953-6205issn
1879-0828pii
S0953620501001704journal_volume
12pub_type
杂志文章abstract：:We report two patients with isolated bone marrow non-Hodgkin's lymphoma and we review the additional 23 cases thus far described. Bicytopenia or pancytopenia and an elevated erythrocyte sedimentation rate were universally present. Some 84% of the patients manifested fever of unknown origin (FUO), 64% constitutional sy...
journal_title：European journal of internal medicine
pub_type： 杂志文章
doi：10.1016/s0953-6205(02)00216-9
更新日期：2003-03-01 00:00:00
abstract：:A 60-year-old male was bitten by a venomous snake (Vipera ammodytes) and gradually developed signs of an allergic reaction including generalized itching, generalized rash, and chest discomfort. This was followed by severe retrosternal pain with electrocardiographic evidence of an inferior myocardial ischemia progressi...
journal_title：European journal of internal medicine
pub_type： 杂志文章
doi：10.1016/j.ejim.2005.11.016
更新日期：2006-05-01 00:00:00
abstract：BACKGROUND/OBJECTIVES:There is some evidence to suggest that exercise systolic blood pressure (SBP) may be associated with future risk of stroke in subjects without a history of coronary artery disease (CAD). However, the value of an exaggerated exercise SBP response (EESBPR) for predicting stroke in patients referred ...
journal_title：European journal of internal medicine
pub_type： 杂志文章
doi：10.1016/j.ejim.2014.05.013
更新日期：2014-07-01 00:00:00
abstract：:Oncogenic osteomalacia (OOM) is a rare but curable cause of metabolic bone disease. We report 9 patients with OOM, including 2 patients with occult nasal sinus tumours and 1 in whom a progressive increase in the post-operative FGF23 level heralded the development of metastatic pulmonary disease. The median duration of...
journal_title：European journal of internal medicine
pub_type： 杂志文章
doi：10.1016/j.ejim.2008.01.011
更新日期：2008-11-01 00:00:00
abstract：:Research on multimorbidity has rapidly increased in the last decade, but evidence on the effectiveness of interventions to improve outcomes in patients with multimorbidity is limited. The European Commission is co-funding a large collaborative project named Joint Action on Chronic Diseases and Promoting Healthy Ageing...
journal_title：European journal of internal medicine
pub_type： 杂志文章,评审
doi：10.1016/j.ejim.2015.02.020
更新日期：2015-04-01 00:00:00
abstract：BACKGROUND:According to Swiss legislation, do not attempt cardiopulmonary resuscitation (DNACPR) order can be made at any time by patients only, unless the resuscitation is considered as futile, based on the doctors' evaluation. Little is known about how this decision is made, and which are the factors influencing this...
journal_title：European journal of internal medicine
pub_type： 杂志文章
doi：10.1016/j.ejim.2015.04.003
更新日期：2015-06-01 00:00:00
abstract：:Vasculitis is characterized by inflammation of the vascular wall. It reaches vessels of different sizes and locations, conditioning multisystem and complex manifestations that require a holistic approach. Antineutrophil cytoplasmic antibody-associated vasculitis has an annual incidence rate of 20 per million inhabitan...
journal_title：European journal of internal medicine
pub_type： 杂志文章,评审
doi：10.1016/j.ejim.2020.01.011
更新日期：2020-04-01 00:00:00
abstract：OBJECTIVE:To present our experience regarding the use of a rapid diagnostic test for seasonal influenza A and B. METHODS:We systematically collected and analyzed our data regarding the use of a rapid diagnostic test for seasonal influenza A and B in patients with specific respiratory symptoms that sought medical servi...
journal_title：European journal of internal medicine
pub_type： 临床试验,杂志文章
doi：10.1016/j.ejim.2010.06.013
更新日期：2010-10-01 00:00:00
abstract：BACKGROUND:There are ethnic differences in the incidence of venous thromboembolism. This is the first nationwide study to examine whether there is an association between country of birth in first-generation immigrants and first hospitalisation for venous thrombosis (VT) and pulmonary embolism (PE), and to study whether...
journal_title：European journal of internal medicine
pub_type： 杂志文章
doi：10.1016/j.ejim.2011.07.015
更新日期：2012-01-01 00:00:00
abstract：BACKGROUND:We investigated physician rationale for and against performing routine erythrocyte sedimentation rate (ESR) tests during hospital admissions. METHODS:A comparative, descriptive, prospective study among 82 physicians in 15 departments of internal medicine from two University Medical Centers - A and B - in Is...
journal_title：European journal of internal medicine
pub_type： 杂志文章
doi：10.1016/j.ejim.2006.07.021
更新日期：2007-01-01 00:00:00
abstract：:Diabetes mellitus type 2 (T2DM) has been associated with an increased cardiovascular risk. Improving glycaemia or other traditional cardiovascular risk factors may reduce cardiovascular risk in patients with T2DM. However, single risk intervention in T2DM has not provided convincing evidence in the reduction of cardio...
journal_title：European journal of internal medicine
pub_type： 杂志文章,评审
doi：10.1016/j.ejim.2017.04.017
更新日期：2017-07-01 00:00:00
abstract：:Of the different respiratory disorders that complicate the course of polymyositis, diaphragmatic weakness is one that is seldom described and most often suspected rather than confirmed. We report a case of severe diaphragmatic weakness as a cause of acute respiratory failure revealing a polymyositis. The diaphragmatic...
journal_title：European journal of internal medicine
pub_type： 杂志文章
doi：10.1016/s0953-6205(02)00015-8
更新日期：2002-05-01 00:00:00
abstract：:Portopulmonary hypertension is a form of pulmonary arterial hypertension that has gained interest in recent years with the development of liver transplantation techniques and new pulmonary vasodilator therapies. Portopulmonary hypertension is defined as pulmonary artery hypertension associated with portal hypertension...
journal_title：European journal of internal medicine
pub_type： 杂志文章,评审
doi：10.1016/j.ejim.2011.02.018
更新日期：2011-10-01 00:00:00
abstract：BACKGROUND:Tachycardia is a reliable predictor of adverse outcomes in normotensive patients with acute pulmonary embolism (PE). However, different prognostic relevant heart rate thresholds have been proposed. The aim of the study was to investigate the prognostic performance of different thresholds used for defining ta...
journal_title：European journal of internal medicine
pub_type： 杂志文章
doi：10.1016/j.ejim.2020.08.009
更新日期：2020-12-01 00:00:00
abstract：:Background: Essential mixed cryoglobulinemia (EMC) is a systemic disease frequently associated with chronic viral hepatitis. This study was conducted in order to assess the prevalence of EMC in patients with hepatitis B virus (HBV) or hepatitis C virus (HCV) infections. We also evaluated the possible associations of E...
journal_title：European journal of internal medicine
pub_type： 杂志文章
doi：10.1016/s0953-6205(01)00151-0
更新日期：2001-09-01 00:00:00
abstract：BACKGROUND:Visceral obesity increases the risk of arterial hypertension (78% of cases of hypertension in men and 65% of cases in women). The aim of the study is to assess the role of visceral obesity in causing resistant hypertension (RH). METHODS:The survey was performed on 5065 hypertensive patients with visceral ob...
journal_title：European journal of internal medicine
pub_type： 杂志文章
doi：10.1016/j.ejim.2012.04.012
更新日期：2012-10-01 00:00:00
abstract：BACKGROUND:Diabetes mellitus can cause a wide variety of vascular complications and it is one of the major risk factors for cardiovascular diseases (CVD). High glucose can induce vascular endothelial cell apoptosis. In this study, we investigated the effect of radix hedysari polysaccharide (HPS) on the depression of ap...
journal_title：European journal of internal medicine
pub_type： 杂志文章
doi：10.1016/j.ejim.2011.10.006
更新日期：2012-04-01 00:00:00
abstract：AIM:We investigated the association among long-term proton-pump inhibitors (PPIs) use with serum magnesium (Mg) levels in chronic hemodialysis (HD) patients, as well as possible association among PPI use and increased risk of cardiovascular (CVD) morbidity in HD patients. METHODS:Of 418 HD patients that were screened ...
journal_title：European journal of internal medicine
pub_type： 杂志文章
doi：10.1016/j.ejim.2016.01.026
更新日期：2016-05-01 00:00:00
abstract：:Fasciitis-panniculitis syndrome (FPS) is a condition characterized by inflammation of the subcutaneous cellular tissue, the aponeurosis and, eventually, the muscles. A 49-year-old female who was previously diagnosed as having retroperitoneal fibrosis presented recurrent episodes of intermittent inflammation of her lim...
journal_title：European journal of internal medicine
pub_type： 杂志文章
doi：10.1016/j.ejim.2006.09.025
更新日期：2007-05-01 00:00:00
abstract：BACKGROUND:Acute kidney injury (AKI) is a serious complication in patients hospitalized for decompensated heart failure (HF). Currently, AKI definitions consider creatinine levels at admission as reference of baseline renal function (RF). However, renal impairment may already be present at admission. We aimed to study ...
journal_title：European journal of internal medicine
pub_type： 杂志文章
doi：10.1016/j.ejim.2020.02.028
更新日期：2020-07-01 00:00:00
abstract：:Venous and arterial thromboses have traditionally been regarded as separate diseases with different causes. However, recent epidemiological studies have documented an association between these vascular complications, probably due to the presence of more overlapping risk factors than previously recognized. This narrati...
journal_title：European journal of internal medicine
pub_type： 杂志文章,评审
doi：10.1016/j.ejim.2012.02.008
更新日期：2012-06-01 00:00:00
abstract：:In all industrialized countries, life expectancy has risen in the past 100 years. The incidence of elderly patients reaching end-stage renal disease (ESRD) and requiring renal replacement therapy has also increased. During the past few decades, the pattern of ESRD has changed significantly with the emerging predominan...
journal_title：European journal of internal medicine
pub_type： 杂志文章
doi：10.1016/s0953-6205(01)00121-2
更新日期：2001-04-01 00:00:00
abstract：:Erdheim-Chester disease (ECD) is rare form of non-Langerhans cells histiocytosis with multiorgan involvement. Individuals are more frequently affected in their fifth decade and there is a slight male prevalence. Recent studies have demonstrated that ECD patients bare mutations in the proto-oncogene BRAF (and more rare...
journal_title：European journal of internal medicine
pub_type： 杂志文章,评审
doi：10.1016/j.ejim.2015.03.004
更新日期：2015-05-01 00:00:00
abstract：:Anthracosis is a form of pneumoconiosis caused by coal dust or by a smoky and polluted environment. Anthracosis often presents in pulmonary form; only rarely are extrathoracic, esophageal, and mediastinal anthracoses documented. We report a rare case of anthracosis with multiple mediastinal lymphadenopathy. ...
journal_title：European journal of internal medicine
pub_type： 杂志文章
doi：10.1016/j.ejim.2003.09.001
更新日期：2003-11-01 00:00:00
abstract：BACKGROUND:In recent decades, the growing incidence of patients with heart failure who have preserved systolic function, underlines the need to differentiate between heart failure due to diastolic dysfunction and that due to systolic dysfunction. OBJECTIVE:To develop a prediction profile of clinical parameters that en...
journal_title：European journal of internal medicine
pub_type： 杂志文章
doi：10.1016/j.ejim.2008.09.001
更新日期：2009-05-01 00:00:00
abstract：BACKGROUND:Tocilizumab, a humanized monoclonal antibody, targets IL-6 receptors blocking downstream pro-inflammatory effects of IL-6. In preliminary reports it was suggested to be beneficial in patients with severe COVID-19. METHODS:In this open-label prospective study we describe clinical characteristics and outcome ...
journal_title：European journal of internal medicine
pub_type： 杂志文章
doi：10.1016/j.ejim.2020.05.011
更新日期：2020-06-01 00:00:00
abstract：:Background: Parkinson's disease is a common neurodegenerative disorder that affects an increasing number of older people every year. Dysphagia is not only a common feature, but one that results in poor nutrition and an increased risk of bronchopneumonia. Previous work has suggested that the oral flora is altered in pa...
journal_title：European journal of internal medicine
pub_type： 杂志文章
doi：10.1016/j.ejim.2003.09.009
更新日期：2003-12-01 00:00:00
abstract：:IgG4-related disease (IgG4-RD) is an autoimmune disorder characterized by substantial infiltration of plasma cells with IgG4 in target organs. Lung manifestations predominantly present as inflammatory pseudotumor, interstitial pneumonitis, organizing pneumonia, and lymphomatoid granulomatosis. There is no specific dia...
journal_title：European journal of internal medicine
pub_type： 杂志文章,评审
doi：10.1016/j.ejim.2019.06.010
更新日期：2019-08-01 00:00:00
abstract：BACKGROUND:Acute kidney injury (AKI) is independently associated with increased morbidity and mortality. Quality improvement has been identified as an important goal in the care of patients with AKI. Different settings can be targeted to improve AKI care, broadly classified these include the inpatient and outpatient en...
journal_title：European journal of internal medicine
pub_type： 杂志文章
doi：10.1016/j.ejim.2020.04.056
更新日期：2020-10-01 00:00:00
abstract：AIM:Dual blockade of renin-angiotensin system (RAS) has increased antiproteinuric effects and it has been increasingly used on patients with proteinuria, but could have secondary effects when this kind of treatment is administered to patients with single functioning kidney. The aim of this study has been to assess the ...
journal_title：European journal of internal medicine
pub_type： 杂志文章
doi：10.1016/j.ejim.2008.06.002
更新日期：2009-03-01 00:00:00
