An update on IgG4-related lung disease.

Abstract:

:IgG4-related disease (IgG4-RD) is an autoimmune disorder characterized by substantial infiltration of plasma cells with IgG4 in target organs. Lung manifestations predominantly present as inflammatory pseudotumor, interstitial pneumonitis, organizing pneumonia, and lymphomatoid granulomatosis. There is no specific diagnostic test for IgG4-related lung disease (IgG4-RLD), and excluding diseases that mimic IgG4-RLD is important. Corticosteroids with or without disease-modifying anti-rheumatic drugs are recommended for treatment. The long-term prognosis of IgG4-RLD remains unknown. In this review, we summarized the current diagnostic algorithms and discussed potential biomarkers for future investigation.

journal_name

Eur J Intern Med

authors

Morales AT,Cignarella AG,Jabeen IS,Barkin JS,Mirsaeidi M

doi

10.1016/j.ejim.2019.06.010

subject

Has Abstract

pub_date

2019-08-01 00:00:00

pages

18-24

eissn

0953-6205

issn

1879-0828

pii

S0953-6205(19)30193-1

journal_volume

66

pub_type

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