Hypersersensitivity and Kounis syndrome due to a viper bite.

Abstract:

:A 60-year-old male was bitten by a venomous snake (Vipera ammodytes) and gradually developed signs of an allergic reaction including generalized itching, generalized rash, and chest discomfort. This was followed by severe retrosternal pain with electrocardiographic evidence of an inferior myocardial ischemia progressing to acute myocardial infarction. Cardiac enzymes and troponin, serum tryptase, and histamine were elevated. Coronary arteriography showed normal coronary arteries. This is a characteristic type I variant of Kounis syndrome, which is the concurrence of acute coronary syndromes with conditions associated with mast cell activation including allergic or hypersensitivity reactions as well as anaphylactic or anaphylactoid reactions. This is the first report to show that viper bites can induce allergic angina and/or allergic myocardial infarction.

journal_name

Eur J Intern Med

authors

Frangides C,Kouni S,Niarchos C,Koutsojannis C

doi

10.1016/j.ejim.2005.11.016

subject

Has Abstract

pub_date

2006-05-01 00:00:00

pages

215-6

issue

3

eissn

0953-6205

issn

1879-0828

pii

S0953-6205(06)00030-6

journal_volume

17

pub_type

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