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Effectiveness of Lanzhou lamb rotavirus vaccine against rotavirus gastroenteritis requiring hospitalization: a matched case-control study.

Abstract：

:We sought to determine the vaccine effectiveness (VE) of Lanzhou lamb rotavirus (LLR) vaccine against rotavirus gastroenteritis in children <5 requiring hospitalization. Children hospitalized 2002-2004 with rotavirus gastroenteritis were matched by gender, age and community to 838 controls. VE was calculated for one or more doses of LLR vaccine with 95% confidence intervals (CI). For one dose versus zero doses, LLR vaccine VE was 73.3% (95% CI, range 61.2-81.6%). VE of one dose versus zero doses was higher in children 12-23 months than in children 2-11 months (80.9% versus 60.0%). We found one dose moderately effective in preventing rotavirus gastroenteritis requiring hospitalization.

journal_name

Vaccine

journal_title

Vaccine

authors

Fu C,Wang M,Liang J,He T,Wang D,Xu J

doi

10.1016/j.vaccine.2007.10.036

subject

Has Abstract

pub_date

2007-12-17 00:00:00

pages

8756-61

issue

52

eissn

0264-410X

issn

1873-2518

pii

S0264-410X(07)01200-5

journal_volume

25

pub_type

杂志文章

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