当前位置： SCI文献检索 > EUROPEAN JOURNAL OF HAEMATOLOGY期刊下所有文献 > Use of advanced red blood cell and reticulocyte indices improves the accuracy in diagnosing iron deficiency in pregnant women at term.

Use of advanced red blood cell and reticulocyte indices improves the accuracy in diagnosing iron deficiency in pregnant women at term.

Abstract：

OBJECTIVES:Detection of iron deficiency during pregnancy with hemoglobin (Hb) and serum measurements is insignificant as the measurements may be affected by e.g. hemodilution or accelerated erythropoiesis. This study tests whether cell indices will give a more reliable measure of iron deficiency in pregnant women at term. METHODS:The population was 202 pregnant women. Using the ADVIA 120 hematology system, Hb, mean cell volume (MCV), percentage of hypochromic red blood cells (%HYPOm) and reticulocytes (%HYPOr), and cellular hemoglobin in reticulocytes (CHr) were tested. Additionally, transferrin saturation (TfSat), ferritin, and transferrin receptor (TfR) were analyzed. Receiver operating characteristic (ROC) curves and area under the ROC curves (AUC) were used as statistical methods. RESULTS:When TfSat (< or = 11%) was used as the reference test for iron deficiency, %HYPOm and CHr had a sensitivity of 58.1% and 80.7%, while the specificities were 82.6% and 71.3%, respectively. Additionally, the AUC values were %HYPOr 0.80, CHr 0.79, ferritin 0.77, %HYPOm 0.75, TfR 0.67, MCV 0.63 and Hb 0.64. The results provided by the cell indices alone (%HYPOm or CHr) were in good agreement with the results based on the usage of a combination of three commonly used tests (Hb, MCV, ferritin). CONCLUSIONS:This study suggests that the most practical way to diagnose iron deficiency in pregnant women at term is to use cell indices such as CHr and %HYPOm provided by the automated hematological analyzer. Further studies are needed to determine the usefulness of the cell indices in diagnosing iron deficiency longitudinally during the course of pregnancy.

journal_name

Eur J Haematol

journal_title

European journal of haematology

authors

Ervasti M,Kotisaari S,Heinonen S,Punnonen K

doi

10.1111/j.1600-0609.2007.00964.x

subject

Has Abstract

pub_date

2007-12-01 00:00:00

pages

539-45

issue

6

eissn

0902-4441

issn

1600-0609

pii

EJH964

journal_volume

79

pub_type

杂志文章

相关文献

EUROPEAN JOURNAL OF HAEMATOLOGY文献大全
  • Evaluation of the prognostic relevance of L-selectin and ICAM1 expression in myelodysplastic syndromes.

    abstract：OBJECTIVES:An aberrant pattern of expression of L-selectin and intercellular adhesion molecule 1 (ICAM1) may characterise CD34+ blast cells in myelodysplastic syndromes (MDS) and secondary acute myeloid leukaemia (sAML). METHODS:In a three-colour flow cytometric assay, we evaluated the expression of L-selectin and ICA...

    journal_title：European journal of haematology

    pub_type： 杂志文章

    doi：10.1111/j.1600-0609.2007.00986.x

    authors： Buccisano F,Maurillo L,Tamburini A,Del Poeta G,Del Principe MI,Ammatuna E,Consalvo MI,Campagna S,Ottaviani L,Sarlo C,Renzi D,Faccia S,Fraboni D,Lo Coco F,Amadori S,Venditti A

    更新日期：2008-02-01 00:00:00

  • Accumulation of vincristine and doxorubicin in malignant lymphocytes with different immunophenotypes.

    abstract：:Cellular accumulation of vincristine (VCR) and doxorubicin (DOX) was studied in 15 patients with low-grade B-cell malignancies. Their leukemic lymphocytes were isolated and the effect of verapamil on drug uptake was studied. The immunophenotype was characterized using anti-IgM, -IgD, -B 1, monoclonal antibodies. The m...

    journal_title：European journal of haematology

    pub_type： 杂志文章

    doi：10.1111/j.1600-0609.1989.tb00334.x

    authors： Reizenstein P,Kapoor R,Gruber A,Peterson C

    更新日期：1989-11-01 00:00:00

  • Patient-specific analysis of FLT3 internal tandem duplications for the prognostication and monitoring of acute myeloid leukemia.

    abstract：OBJECTIVES:Internal tandem duplications (ITDs) of the fms-like tyrosine kinase 3 ( FLT3) gene occur in 13-35% of patients with acute myeloid leukemia (AML). FLT3-ITD is associated with poor clinical outcome and is an indication for allogeneic stem cell transplantation (allo-SCT). METHODS:To investigate FLT3-ITD length...

    journal_title：European journal of haematology

    pub_type： 杂志文章

    doi：10.1111/j.1600-0609.2012.01785.x

    authors： Schiller J,Praulich I,Krings Rocha C,Kreuzer KA

    更新日期：2012-07-01 00:00:00

  • Zoledronate-induced remission of acute panmyelosis with myelofibrosis.

    abstract：:Acute panmyelosis with myelofibrosis is a rare and aggressive form of acute myeloid leukemia. We describe a new case with a huge proliferation of megakaryocytes, blast cells and reticulin fibers. The patient was treated with zoledronate, a third-generation bisphosphonate, and a gradual recovery from pancytopenia was o...

    journal_title：European journal of haematology

    pub_type： 杂志文章

    doi：10.1111/j.1600-0609.2004.00277.x

    authors： Español I,Romagosa V,Berlanga J,Domingo A,Losa F,Heras L,Janáriz J

    更新日期：2004-09-01 00:00:00

  • Severe IgA-mediated auto-immune haemolytic anaemia in a 48-yr-old woman.

    abstract：:Auto-immune haemolytic anaemia (AIHA) is characterised by haemolysis associated with the presence of the immunoglobulins IgG, IgM or IgA, and/or components of the complement system on the red cell membrane. The immunoglobulins react as auto-antibodies against the red cell antigens of the patient. IgG antibodies and th...

    journal_title：European journal of haematology

    pub_type： 杂志文章

    doi：10.1034/j.1600-0609.2003.02846.x

    authors： Bardill B,Mengis C,Tschopp M,Wuillemin WA

    更新日期：2003-01-01 00:00:00

  • Direct oral anticoagulants for atrial fibrillation in patients with congenital factor VII deficiency.

    abstract：:The management of anticoagulant therapy (OAT) in patients with factor VII (FVII) deficiency is a very challenging clinical issue, as warfarin further reduces FVII levels, thus potentially increasing bleeding risk. On the other hand, the International Normalized Ratio test is misleading in such patients, as they do not...

    journal_title：European journal of haematology

    pub_type： 杂志文章,meta分析

    doi：10.1111/ejh.13246

    authors： Arletti L,Coluccio V,Romagnoli E,Luppi M,Marietta M

    更新日期：2019-07-01 00:00:00

  • BCR-ABL1 molecular remission after 90Y-epratuzumab tetraxetan radioimmunotherapy in CD22+ Ph+ B-ALL: proof of principle.

    abstract：:Although targeted therapies are used increasingly in hematologic malignancies, we are unaware of any prior studies of radioimmunotherapy (RAIT) in B-acute lymphoblastic leukemia (ALL), even though this radiosensitive tumor expresses CD22, potentially a good target for this approach. Here, we report a patient with Phil...

    journal_title：European journal of haematology

    pub_type： 杂志文章

    doi：10.1111/ejh.12183

    authors： Chevallier P,Bodet-Milin C,Robillard N,Eugene T,Menard A,Le Houerou C,Guillaume T,Delaunay J,Escoffre-Barbe M,Wegener WA,Goldenberg DM,Kraeber-Bodéré F

    更新日期：2013-12-01 00:00:00

  • Inherited or acquired modifiers of iron status may dramatically affect the phenotype in dehydrated hereditary stomatocytosis.

    abstract：:Severe iron overload is frequent in dehydrated hereditary stomatocytosis (DHSt) despite well-compensated hemolysis and no or little transfusion requirement. We investigated 4 patients with proven DHSt, in whom the degree of hemolysis was closely related to iron status. Genetic modifiers increasing iron stores (HFE:pCy...

    journal_title：European journal of haematology

    pub_type：

    doi：10.1111/ejh.13135

    authors： Orvain C,Da Costa L,Van Wijk R,Pissard S,Picard V,Mansour-Hendili L,Cunat S,Giansily-Blaizot M,Cartron G,Schved JF,Aguilar-Martinez P

    更新日期：2018-10-01 00:00:00

  • A comparison of Campath and Thymoglobulin as part of the conditioning before allogeneic hematopoietic stem cell transplantation.

    abstract：BACKGROUND:In vivo T-cell depletion with anti-thymocyte globulin is a commonly used strategy for the prevention of graft-versus-host disease (GVHD) and to avoid rejection after hematopoietic stem cell transplantation (HSCT). METHODS:We compared 36 patients given Campath (alemtuzumab) as part of the conditioning with a...

    journal_title：European journal of haematology

    pub_type： 杂志文章

    doi：10.1111/j.1600-0609.2010.01537.x

    authors： Norlin AC,Remberger M

    更新日期：2011-01-01 00:00:00

  • Cost-effectiveness of rituximab as maintenance treatment for relapsed follicular lymphoma: results of a population-based study.

    abstract：OBJECTIVES:On the basis of two population-based registries, our study aims to calculate the real-world cost-effectiveness of rituximab maintenance compared with observation in relapsed or refractory follicular lymphoma patients who responded to second-line chemotherapy. METHODS:Data were obtained from the EORTC20981 t...

    journal_title：European journal of haematology

    pub_type： 杂志文章

    doi：10.1111/ejh.12264

    authors： Blommestein HM,Issa DE,Pompen M,Ten Hoor G,Hogendoorn M,Joosten P,Zweegman S,Huijgens PC,Uyl-de Groot CA

    更新日期：2014-01-01 00:00:00

  • Reticulocyte crisis after splenectomy: evidence for delayed red cell maturation?

    abstract：:In whole blood from splenectomized subjects (n = 8) in a steady state an increased number of reticulocytes was observed (14.0 +/- 7.8% versus 3.6 +/- 2.4% controls: p less than 0.05). Cell fractionation on density showed that reticulocytes, as in normals, are more or less confined to the least dense fraction; cell fra...

    journal_title：European journal of haematology

    pub_type： 杂志文章

    doi：10.1111/j.1600-0609.1988.tb00872.x

    authors： De Haan LD,Werre JM,Ruben AM,Huls AH,de Gier J,Staal GE

    更新日期：1988-07-01 00:00:00

  • Lenalidomide as maintenance treatment for patients with multiple myeloma after autologous stem cell transplantation: A pharmaco-economic assessment.

    abstract：OBJECTIVE:Autologous stem cell transplantation (ASCT) has improved progression-free survival (PFS) and overall survival in eligible patients with newly diagnosed multiple myeloma (NDMM); however, relapse occurs. Maintenance therapy with lenalidomide (Len-Mt) extends survival and delays relapse and the subsequent initia...

    journal_title：European journal of haematology

    pub_type： 杂志文章

    doi：10.1111/ejh.13497

    authors： Uyl-de Groot CA,Ramsden R,Lee D,Boersma J,Zweegman S,Dhanasiri S

    更新日期：2020-11-01 00:00:00

  • Cancer-related anemia in a rat model: alpha2-macroglobulin from Yoshida sarcoma shortens erythrocyte survival.

    abstract：:Implantation of Yoshida ascites sarcoma in rats was found to lead to a reduction in the hemoglobin content, the erythrocyte count and the packed cell volume of blood to 30% of normal in 4 d; however, there was no decrease in the mean cell hemoglobin, the mean cell volume and the mean corpuscular hemoglobin concentrati...

    journal_title：European journal of haematology

    pub_type： 杂志文章

    doi：10.1034/j.1600-0609.2002.00543.x

    authors： Bhanushali AA,Raghunathan R,Kalraiya RD,Mehta NG

    更新日期：2002-01-01 00:00:00

  • Feasibility of fludarabine added to VAD during induction therapy in multiple myeloma: a randomised phase II-study.

    abstract：:Multiple myeloma (MM) is considered to be an essentially incurable haematological malignant disease, probably because of the existence of resistant clonal precursor cell with self-renewal capacity. Recent data have indicated that the myeloma cell hierarchy includes circulating clonal memory B cells, which differ consi...

    journal_title：European journal of haematology

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1034/j.1600-0609.2003.00068.x

    authors： Björkstrand B,Rasmussen T,Remes K,Gruber A,Pelliniemi TT,Johnsen HE

    更新日期：2003-06-01 00:00:00

  • The antiplatelet activity of Escherichia coli lipopolysaccharide is mediated through a nitric oxide/cyclic GMP pathway.

    abstract：:In this study, Escherichia coli LPS dose-dependently (100-500 microg/ml) and time-dependently (10-60 min) inhibited platelet aggregation in human and rabbit platelets stimulated by agonists. LPS also dose-dependently inhibited the intracellular Ca2+ mobilization in human platelets stimulated by collagen. In addition, ...

    journal_title：European journal of haematology

    pub_type： 杂志文章

    doi：10.1111/j.1600-0609.1999.tb01909.x

    authors： Sheu JR,Hung WC,Su CH,Lin CH,Lee LW,Lee YM,Yen MH

    更新日期：1999-05-01 00:00:00

  • Congenital haemolytic anaemia in a low birth weight infant due to congenital stomatocytosis.

    abstract：:A baby girl born at 31 weeks gestation showed severe haemolytic anaemia and hyperbilirubinaemia which led to exchange transfusion within the first 12 hours of life. There was no blood group incompatibility between mother and child but there was a marked stomatocytosis of the baby's red blood cells. Family history reve...

    journal_title：European journal of haematology

    pub_type： 杂志文章

    doi：10.1111/j.1600-0609.1991.tb00554.x

    authors： Huppi PS,Ott P,Amato M,Schneider H

    更新日期：1991-07-01 00:00:00

  • Single-agent thalidomide induces response in T-cell lymphoma.

    abstract：:T-cell lymphoma is an aggressive lymphoma that cannot be cured despite aggressive therapy, including autologous stem cell transplantation. Thalidomide is an immunomodulatory drug with numerous properties that has proven effective in relapsed multiple myeloma and, to a lesser extent, in other hematologic diseases. We r...

    journal_title：European journal of haematology

    pub_type： 杂志文章

    doi：10.1111/j.1600-0609.2004.00362.x

    authors： Damaj G,Bouabdallah R,Vey N,Bilger K,Mohty M,Gastaut JA

    更新日期：2005-02-01 00:00:00

  • Effect of cytokines on the toxicity of cytostatic drugs on leukemic cells in vitro and in vivo.

    abstract：:Most cytostatic drugs exert their effect on cells in active cell cycle. To improve the effect of cytostatic drugs we have tried, prior to treatment in vitro, to recruit tumor cells from G0 with growth factors. Leukemic cells from the bone marrows of 26 patients with AML and CML in blast crisis were incubated with G-CS...

    journal_title：European journal of haematology

    pub_type： 杂志文章

    doi：10.1111/j.1600-0609.1996.tb00285.x

    authors： Sundman-Engberg B,Tidefelt U,Paul C

    更新日期：1996-01-01 00:00:00

  • 'Auto'-immune neutropenia after allogeneic bone marrow transplantation unresponsive to conventional immunosuppression but resolving promptly after splenectomy.

    abstract：:A 32-year-old male presented with isolated neutropenia 6 months after allogeneic bone marrow transplantation for CML from his HLA-matched brother. The presence of granulocyte-specific IgM and IgG antibodies in the patient's serum indicated an immune-mediated basis for the neutropenia. A variety of manoeuvres to suppre...

    journal_title：European journal of haematology

    pub_type： 杂志文章

    doi：10.1111/j.1600-0609.1988.tb00889.x

    authors： Koeppler H,Goldman JM

    更新日期：1988-08-01 00:00:00

  • Treatment of 34 patients with myelodysplastic syndromes with 13-CIS retinoic acid.

    abstract：:Thirty-four patients with myelodysplastic syndromes, 23 men and 11 women, aged between 47 and 80 years, with all types of myelodysplastic syndromes were treated with 13-cis-retinoic acid. The dose of retinoic acid ranged between 10 and 60 mg/m2/daily and was administered in combination with vitamin E to diminish side ...

    journal_title：European journal of haematology

    pub_type： 临床试验,杂志文章

    doi：10.1111/j.1600-0609.1995.tb00263.x

    authors： Bourantas KL,Tsiara S,Christou L

    更新日期：1995-10-01 00:00:00

  • Prophylaxis of cytomegalovirus infection with ganciclovir in allogeneic marrow transplantation.

    abstract：:Cytomegalovirus (CMV) infection is one of the most common causes of morbidity and mortality after allogeneic marrow transplantation. We studied 14 consecutive CMV-seropositive patients adding ganciclovir (2.5 mg/kg i.v. every 8 hours for 7 days prior to transplant and 6 mg/kg three times a week after neutrophils becam...

    journal_title：European journal of haematology

    pub_type： 临床试验,杂志文章

    doi：10.1111/j.1600-0609.1991.tb01863.x

    authors： Yau JC,Dimopoulos MA,Huan SD,Tarrand JJ,Spencer V,Spitzer G,Meneghetti CM,Wallerstein RO,Andersson BS,LeMaistre CF

    更新日期：1991-11-01 00:00:00

  • An Arg545----Cys545 substitution mutation of the von Willebrand factor in type IIB von Willebrand's disease.

    abstract：:Type IIB is a special variant of von Willebrand's disease, characterized by an abnormal von Willebrand factor which shows an increased interaction with platelets. This interaction sometimes causes platelet aggregation and thrombocytopenia in vivo. It involves the glycoprotein-Ib (GPIb) receptor on platelets and corres...

    journal_title：European journal of haematology

    pub_type： 杂志文章

    doi：10.1111/j.1600-0609.1991.tb01858.x

    authors： Donnér M,Andersson AM,Kristoffersson AC,Nilsson IM,Dahlbäck B,Holmberg L

    更新日期：1991-11-01 00:00:00

  • Anagrelide influences thrombotic risk, and prolongs progression-free and overall survival in essential thrombocythaemia vs hydroxyurea plus aspirin.

    abstract：OBJECTIVE:We report an extension study of patients with essential thrombocythaemia (ET) in the Hungarian Myeloproliferative Neoplasm (HUMYPRON) Registry, which demonstrated that over 6 years anagrelide significantly decreased the number of patients experiencing minor arterial and minor venous thrombotic events (TEs) vs...

    journal_title：European journal of haematology

    pub_type： 杂志文章

    doi：10.1111/ejh.13459

    authors： Kellner A,Dombi P,Illes A,Demeter J,Homor L,Ercsei I,Simon Z,Karadi E,Herczeg J,Gy Korom V,Gasztonyi Z,Szerafin L,Udvardy M,Egyed M

    更新日期：2020-10-01 00:00:00

  • Real-world outcomes for 205 patients with chronic lymphocytic leukemia treated with ibrutinib.

    abstract：:Ibrutinib has now been approved for treatment of chronic lymphocytic leukemia (CLL) in both front-line setting and as later-line treatment. However, knowledge about the outcomes and adverse events (AE) among patients at a population-based level is still limited. OBJECTIVES:To report outcomes and AEs in a population-b...

    journal_title：European journal of haematology

    pub_type： 杂志文章

    doi：10.1111/ejh.13499

    authors： Aarup K,Rotbain EC,Enggaard L,Pedersen RS,Bergmann OJ,Thomsen RH,Frederiksen M,Frederiksen H,Nielsen T,Christiansen I,Andersen MA,Niemann CU

    更新日期：2020-11-01 00:00:00

  • Intracellular HMGB1 transactivates the human IL1B gene promoter through association with an Ets transcription factor PU.1.

    abstract：:High mobility group box 1 protein (HMGB1), originally described as a non-histone, DNA binding protein, was recently identified as a late mediator of inflammation via its extracellular release from activated macrophages/monocytes. In the present study, we report that intracellular HMGB1 synergizes with a macrophage/mon...

    journal_title：European journal of haematology

    pub_type： 杂志文章

    doi：10.1111/j.1600-0609.2007.00981.x

    authors： Mouri F,Tsukada J,Mizobe T,Higashi T,Yoshida Y,Minami Y,Izumi H,Kominato Y,Kohno K,Tanaka Y

    更新日期：2008-01-01 00:00:00

  • BCL3 rearrangement, amplification and expression in diffuse large B-cell lymphoma.

    abstract：AIMS:Aim of the study is to investigate diffuse large B-cell lymphoma (DLBCL) for the presence of BCL3 gene rearrangement and protein expression and to correlate these with immunophenotypic subsets of DLBCL. We aimed to investigate the pathogenetic implication of BCL3 in DLBCL. METHODS AND RESULTS:Tissue microarray se...

    journal_title：European journal of haematology

    pub_type： 杂志文章

    doi：10.1111/j.1600-0609.2011.01684.x

    authors： Ibrahim HA,Amen F,Reid AG,Naresh KN

    更新日期：2011-12-01 00:00:00

  • Levels of soluble angiogenin in chronic myeloid malignancies: clinical implications.

    abstract：:Angiogenesis is critical for the clinical progression of haematopoietic malignancies and depends on angiogenic factors. Angiogenin is a powerful factor produced by neoplastic cells and host microenvironment. High levels of soluble angiogenin (sAng) correlate with a poor prognosis in patients affected by acute myeloid ...

    journal_title：European journal of haematology

    pub_type： 杂志文章

    doi：10.1111/j.1600-0609.2004.00253.x

    authors： Musolino C,Alonci A,Bellomo G,Loteta B,Quartarone E,Gangemi D,Massara E,Calabrò L

    更新日期：2004-06-01 00:00:00

  • Optimising management of deferasirox therapy for patients with transfusion-dependent thalassaemia and lower-risk myelodysplastic syndromes.

    abstract：:Effective iron chelation therapy is an important part of treatment in patients with transfusion-dependent thalassaemia and lower-risk myelodysplastic syndromes (MDS). Key strategies for optimising iron chelation therapy include ensuring good adherence and preventing and managing adverse events (AEs). Good adherence to...

    journal_title：European journal of haematology

    pub_type： 杂志文章,评审

    doi：10.1111/ejh.13111

    authors： Kattamis A,Aydinok Y,Taher A

    更新日期：2018-09-01 00:00:00

  • Regulatory T-cell phenotype in association with large cell transformation of mycosis fungoides.

    abstract：INTRODUCTION:Tumor cells of primary cutaneous T-cell lymphomas are able to adopt a regulatory T-cell phenotype in vitro. The significance of this finding in vivo is matter of debate. METHODS:We stained five cases with transformed mycosis fungoides (MF) with an antibody against FOXP3, which is a sensitive and specific ...

    journal_title：European journal of haematology

    pub_type： 杂志文章

    doi：10.1111/j.1600-0609.2006.00809.x

    authors： Hallermann C,Niermann C,Schulze HJ

    更新日期：2007-03-01 00:00:00

  • Is valganciclovir really effective in primary effusion lymphoma: case report of an HIV(-) EBV(-) HHV8(+) patient.

    abstract：:Primary effusion lymphoma (PEL) is a human herpesvirus 8 (HHV8) associated lymphoproliferative disease characterized by effusions in body cavities, and lack of tumor mass. Valganciclovir is a treatment option in PEL, however, little is known about its clinical efficacy. Ganciclovir has been reported to be effective in...

    journal_title：European journal of haematology

    pub_type： 杂志文章

    doi：10.1111/ejh.12174

    authors： Ozbalak M,Tokatlı I,Özdemirli M,Tecimer T,Ar MC,Örnek S,Koroglu A,Laleli Y,Ferhanoglu B

    更新日期：2013-11-01 00:00:00