Abstract:
OBJECTIVE:To compare the oocyte quality and intracytoplasmic sperm injection performance in women with isolated polycystic ovaries or polycystic ovarian syndrome. DESIGN:Retrospective study. SETTING:Fertility unit. POPULATION:Three study groups were identified: women with PCO-only morphology (50 cycles), PCOS (51 cycles) and age matched control group (104 cycles) with isolated male factor infertility necessitating ICSI. METHOD:Controlled ovarian hyperstimulation and ICSI. MAIN OUTCOME MEASURES:Response to gonadotropin stimulation, oocyte and embryo quality, clinical pregnancy rate and pregnancy outcome. RESULTS:Despite a significantly lower total gonadotropin dose, a significantly higher serum E2 level was attained in both the PCOS and the PCO-only groups compared to the control group. Although significantly more oocytes were retrieved in the PCOS and PCO-only groups, the number of 2-pronuclear embryos was similar to controls. No significant differences were noted in the maturity of the oocytes, oocyte dysmorphism, embryo quality, implantation and pregnancy rates among the three groups. However the clinical miscarriage rate was significantly lower in women with PCO-only morphology group (15.4 versus 31%, P < 0.05) than in the PCOS group. CONCLUSION:Women with PCO-only appearance have shown to have similar characteristics to women with PCOS in terms of ovarian response to hMG stimulation, oocyte and embryo quality and pregnancy rates. However miscarriage rates were significantly lower in the PCO-only group than the PCOS group. Our findings suggest that factors unrelated to oocyte and embryo morphology present in PCOS patients may be instrumental in adverse reproductive outcomes in these women.
journal_name
Arch Gynecol Obstetjournal_title
Archives of gynecology and obstetricsauthors
Sahu B,Ozturk O,Ranierri M,Serhal Pdoi
10.1007/s00404-007-0462-xsubject
Has Abstractpub_date
2008-03-01 00:00:00pages
239-44issue
3eissn
0932-0067issn
1432-0711journal_volume
277pub_type
杂志文章abstract:PURPOSE:Ovarian cancer is the most lethal gynaecological malignancy. Despite the introduction of bevacizumab, standard chemotherapy has remained largely unchanged and the vast majority of patients will relapse within the first two years of diagnosis. However, results from recent clinical trials demonstrating clinical b...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章,评审
doi:10.1007/s00404-020-05677-1
更新日期:2020-11-01 00:00:00
abstract::It is rare to find osteoclastic giant cells (OGCs) as a stromal reaction in uterine adenocarcinoma of endometrium. Here, we report a case of a 60-year-old female diagnosed with adenocarcinoma of endometrium. Total hysterectomy with bilateral salpingo-oopherectomy and removal of pelvic lymphnodes was performed. Histolo...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-011-2089-1
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abstract:OBJECTIVE:To determine the perinatal outcome associated with cup detachment during vacuum-assisted vaginal delivery (VAVD). METHODS:A retrospective cohort study of all women attempting VAVD in a tertiary hospital (2012-2014). Singleton-term pregnancies were included. Antepartum fetal death and major fetal structural o...
journal_title:Archives of gynecology and obstetrics
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doi:10.1007/s00404-017-4507-5
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abstract:OBJECTIVE:A previous decision analysis models for two strategic choices for trial of labor or repeated cesarean after prior cesarean concluded that the degree of wish for an additional future pregnancy appeared to be a major determinant for choice between the two strategic options. We had extended the analysis model to...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-007-0373-x
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abstract:OBJECTIVE:Our objective was to establish reference values for ductus venosus flow velocities during ventricular systole (S wave) and diastole (D wave), the lowest forward velocity during atrial contraction (A wave) and different calculated indices [(S-A)/D), (S-A)/Vmean, (S-A)/S, S/A, S/D)]. METHODS:Ductus venosus flo...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-003-0484-y
更新日期:2004-03-01 00:00:00
abstract:BACKGROUND:The Nitric Oxide (NO) system plays an important role in the establishment and maintenance of the feto-placental circulation. Research on the pathogenesis of preeclampsia in several studies has established the involvement of the NO-system in preeclampsia and fetal intrauterine growth restriction (IUGR). In th...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-006-0149-8
更新日期:2006-06-01 00:00:00
abstract:AIM:Breast cancer 2, early onset (BRCA2) has been reported to be associated with familial breast and ovarian cancer. Several proteins interact with conserved regions of BRCA2, which play significant roles in DNA damage repair and centrosomal localization. This study was aimed to identify a novel protein, Wilms tumor 1 ...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
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更新日期:2016-11-01 00:00:00
abstract:BACKGROUND:Membranous dysmenorrhea is a rare entity involving expulsion of fragments of endometrium retaining the shape of the uterus. The condition is often linked to high progesterone levels. An association with a chronic fatigue syndrome was never described. CASE:A 44-year-old woman with a chronic fatigue syndrome ...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章,评审
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更新日期:2009-05-01 00:00:00
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journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
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更新日期:2016-05-01 00:00:00
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journal_title:Archives of gynecology and obstetrics
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abstract::In this study, our aim was to compare the effects of metformin and gonadotropin releasing hormone (GnRH) analogues in clinical and hormonal parameters in women with polycystic ovary syndrome (PCOS). There were 50 women with PCOS who were included in our study and they were divided into two groups. In this randomized t...
journal_title:Archives of gynecology and obstetrics
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:2003-06-01 00:00:00
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journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
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journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章,评审
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更新日期:2012-07-01 00:00:00
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journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章,随机对照试验
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更新日期:2013-01-01 00:00:00
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journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-006-0229-9
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journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
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journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章,meta分析,评审
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journal_title:Archives of gynecology and obstetrics
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journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/BF02264885
更新日期:1995-01-01 00:00:00
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journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章,评审
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更新日期:2013-10-01 00:00:00
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journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-019-05117-9
更新日期:2019-05-01 00:00:00
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journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-009-1329-0
更新日期:2010-07-01 00:00:00
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journal_title:Archives of gynecology and obstetrics
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/s00404-002-0437-x
更新日期:2004-01-01 00:00:00
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journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-016-4107-9
更新日期:2016-08-01 00:00:00
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journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-019-05116-w
更新日期:2019-05-01 00:00:00
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journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-019-05228-3
更新日期:2019-09-01 00:00:00
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journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章,评审
doi:10.1007/s00404-013-2801-4
更新日期:2013-07-01 00:00:00
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journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-007-0320-x
更新日期:2007-08-01 00:00:00
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journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-010-1544-8
更新日期:2011-05-01 00:00:00