Chronic fatigue syndrome: a hormonal origin? A rare case of dysmenorrhea membranacea.

Abstract:

BACKGROUND:Membranous dysmenorrhea is a rare entity involving expulsion of fragments of endometrium retaining the shape of the uterus. The condition is often linked to high progesterone levels. An association with a chronic fatigue syndrome was never described. CASE:A 44-year-old woman with a chronic fatigue syndrome (CFS), presented with membranous dysmenorrhea after taking an oral contraceptive pill containing ethinylestradiol 0.02 mg and desogestrel 0.15 mg for 3 months in a continuous regimen as treatment for dysfunctional bleeding. Oral contraception was discontinued and she resumed normal menstruations. Remarkably, she mentioned complete disappearance of the CFS since expulsion of the tissue and started working again. CONCLUSION:The occurrence of membranous dysmenorrhea with a dissolving chronic fatigue syndrome is very rare and was never described before. This case suggests a hormonal dysfunction as a possible cause of chronic fatigue syndrome. A review of the literature on membranous dysmenorrhea is presented.

journal_name

Arch Gynecol Obstet

authors

Veldman J,Van Houdenhove B,Verguts J

doi

10.1007/s00404-008-0795-0

subject

Has Abstract

pub_date

2009-05-01 00:00:00

pages

717-20

issue

5

eissn

0932-0067

issn

1432-0711

journal_volume

279

pub_type

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