Abstract：
PURPOSE:To evaluate the effect of perioperative blood transfusions on the risk of recurrence of endometrial cancer. METHODS:This study is a retrospective analysis of 358 consecutive patients, without a history of other tumors, who underwent surgery for endometrial cancer between January 2000 and April 2010. RESULTS:Women who did not need any transfusion (N = 331) and patients who received allogenic blood donations (N = 27) were compared in terms of risk of cancer recurrence. The surgical standard procedure included peritoneal washing for cytologic examination, total hysterectomy + bilateral adnexectomy (N = 358), and pelvic lymphadenectomy (N = 227). The two groups were homogeneous in term of age, BMI, previous abdominal surgery, type of intervention, operative time, nodal count, and hospital stay. The median (range) estimated blood loss was higher in the transfusion group, 400 mL (100-2,000 mL), than in the non-transfusion group, 150 mL (10-1,000 mL). Median (range) follow-up was 67.5 months (6-132.4 months). Blood transfusions were associated with a higher relapse rate (P = 0.0021). At multivariate analysis, administration of packed red blood cells remained independently associated with recurrence (OR 4.64; CI 95 % 1.45-14.9), as well as myometrial invasion ≥50 % (OR 2.88; CI 95 % 1.18-7.07) and stage >1 (OR 4.24; CI 95 % 1.75-10.3). CONCLUSIONS:The use of allogenic blood transfusions is associated with a higher risk of recurrence. We hypothesize that this could be due to a transitory perioperative immunodepression that promotes the spread of neoplastic cells.
journal_name
Arch Gynecol Obstetjournal_title
Archives of gynecology and obstetricsauthors
Uccella S,Ghezzi F,Cromi A,Bogani G,Formenti G,Donadello N,Serati M,Bolis Pdoi
10.1007/s00404-012-2668-9subject
Has Abstractpub_date
2013-05-01 00:00:00pages
1009-16issue
5eissn
0932-0067issn
1432-0711journal_volume
287pub_type
杂志文章abstract：OBJECTIVE:Case report of a rare combination of a trisomy 18 and 21 in a dizygotic twin pregnancy in a woman with a history of recurrent miscarriage, a neonatal death, no living offspring and Graves disease. METHODS:Case report and literature search. RESULTS:Only one other report in the literature of a combined trisom...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-007-0378-5
更新日期：2007-11-01 00:00:00
abstract：OBJECTIVE:To identify differentially expressed genes (DEGs) in endometriosis and further analyze molecular mechanisms implicated in disease pathogenesis. MATERIALS AND METHODS:Gene expression data (ID: GSE7846) of human endometrial endothelial cells (HEECs) collected from eutopic endometria tissue of patients with and...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-015-3875-y
更新日期：2016-04-01 00:00:00
abstract：PURPOSE:To establish a reference range for the intracranial translucency (IT). METHODS:In this prospective study, we examined 596 singleton fetuses at 11-14 weeks of gestation using transabdominal ultrasonography. The distribution curves of the anterior-posterior diameter of the IT were established according to the ge...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-014-3410-6
更新日期：2015-03-01 00:00:00
abstract：PURPOSE:In general, male and female are prescribed the same amount of dosage even if most of the cases female required less dosage than male. Physicians are often facing problem on appropriate drug dosing, efficient treatment, and drug safety for a female in general. To identify and synthesize evidence about the effect...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章,评审
doi：10.1007/s00404-017-4363-3
更新日期：2017-06-01 00:00:00
abstract：PURPOSE:To investigate the relationship between hyaluronan binding (HB) assay and pregnancy rates in intrauterine insemination (IUI) cycles. METHODS:This prospective cohort study was done in Hacettepe University, a tertiary care center for reproductive medicine. Seventy-one consecutive couples who suffered from unexpl...
journal_title：Archives of gynecology and obstetrics
pub_type： 临床试验,杂志文章
doi：10.1007/s00404-012-2476-2
更新日期：2012-12-01 00:00:00
abstract：INTRODUCTION:Objective cutaneous metastasis from carcinoma of the uterine cervix is an uncommon occurrence. The outcome of patients with skin metastasis is usually poor as they are often associated with locoregional recurrence. This metastasis impairs the quality of life and shortens survival. Consequently, physicians ...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-008-0617-4
更新日期：2008-11-01 00:00:00
abstract：INTRODUCTION:Radiotherapy is known to cause rarely various malignancies including leukemia, sarcoma, and thyroid and lung carcinoma. Post-radiation sarcomas account for 0.5-5.5% of all sarcomas; and include extra skeletal osteosarcoma, fibrosarcoma leiomyosarcoma, and malignant fibrous histiocytoma. Reports on post rad...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-010-1699-3
更新日期：2011-03-01 00:00:00
abstract：OBJECTIVES:To compare the diagnostic accuracy of brush endometrial sampling with conventional dilatation and curettage in women with abnormal uterine bleeding. PATIENTS AND METHODS:Two hundred and twenty (220) women with abnormal uterine bleeding were included in this comparative study; endometrial sampling was done b...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-014-3523-y
更新日期：2015-05-01 00:00:00
abstract：PURPOSE:The aim of this study is to assess the effects of maternal nifedipine administration on placental and fetal blood flow. METHODS:A total of 29 patients with preterm labor diagnosis admitted to the tertiary care center, Zeynep Kamil Hospital, were evaluated. Before and 24-48 h after administration of oral nifedi...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-018-4839-9
更新日期：2018-10-01 00:00:00
abstract：PURPOSE:The objective of this study was to determine the changes in total plasma thiols (homocysteine, cysteine and cysteinylglycine), lipid peroxidation and nitric oxide concentrations during normal pregnancy. METHODS:These variables were measured in 28 uncomplicated pregnant women at first, second and third trimeste...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-011-2150-0
更新日期：2012-05-01 00:00:00
abstract：BACKGROUND:Desmoid tumors are benign neoplasms that most often arise from muscle aponeurosis and have been associated with both trauma and pregnancy. The etiology of desmoids has not been determined. CLINICAL CHARACTERISTICS:We present here four almost identical cases with desmoids occurring in the same location, the ...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-008-0830-1
更新日期：2009-06-01 00:00:00
abstract：BACKGROUND:Polycystic ovarian syndrome (PCOS) is the most prevalent metabolic disorder in reproductive-age women. It is indeed a multifactorial condition evidenced by ovarian dysfunction, hyperandrogenaemia, infertility, hormonal imbalance and chronic anovulation. Experimental evidence infers that PCOS women are prone ...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章,评审
doi：10.1007/s00404-020-05951-2
更新日期：2021-01-13 00:00:00
abstract：PURPOSE:We evaluated the role of the fossa ischioanalis (FI) in functional relations between the levator ani (LA) and gluteus maximus muscles (GM) in healthy female volunteers. METHODS:Twenty-three nulliparae were examined. Electromyogramms of LA and GM were simultaneously recorded during voluntary contraction of the ...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-012-2377-4
更新日期：2012-10-01 00:00:00
abstract：:We report of a maternal sternal fracture during a spontaneous delivery in a 31-year-old primipara without a suitable trauma. The putative mechanism of fracture was strong hyperflexion of the thoracic spine and additional cervical flexion with pushing the chin to the thorax due to active management of labour. The histo...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-009-1037-9
更新日期：2009-12-01 00:00:00
abstract：INTRODUCTION:Splenic metastasis from endometrial carcinoma is a rare clinical event, with only 11 cases documented previously in the literature. CASE REPORT:A 58-year-old woman had surgery and radiotherapy for stage IIB endometrial carcinoma. Eighteen months later, PET scan discovered a hypermetabolic splenic mass and...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-009-1039-7
更新日期：2009-12-01 00:00:00
abstract：:A 32 years old omani woman G6P4A1 at 39 weeks of pregnancy presented with complaints of headache and picture of eclampsia. Emergency caesarean section was done for maternal and foetal distress. Post caesarean section patient could not be extubated from general anaesthesia. Emergency computed tomography scan of the bra...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-009-1047-7
更新日期：2009-12-01 00:00:00
abstract：OBJECTIVE:To present and discuss 28 female cases with abdominopelvic tuberculosis (TB) and abnormal CA125 levels to better distinguish this disease from advanced ovarian cancer (AOC) and pelvic inflammatory disease (PID). Abdominopelvic tuberculosis (APTB) is one of the extrapulmonary tuberculosis (TB) sites, usually m...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-013-3034-2
更新日期：2014-03-01 00:00:00
abstract：PURPOSE:To evaluate the efficacy and safety for mother and child of using intravenous iron isomaltoside (IV-IIM) during pregnancy. METHODS:Using an appointment register, we retrospectively identified all pregnant women who received a single dose of 1000 or 1500 mg IV-IIM in the maternity ward of Falu Hospital and subs...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章,评审
doi：10.1007/s00404-020-05509-2
更新日期：2020-05-01 00:00:00
abstract：PURPOSE:To develop a predictive model for risk of cesarean section in pregnant women after induction of labor. METHODS:A retrospective cohort study was conducted of 861 induced labors during 2009, 2010, and 2011 at Hospital "La Mancha-Centro" in Alcázar de San Juan, Spain. Multivariate analysis was used with binary lo...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-015-3856-1
更新日期：2016-03-01 00:00:00
abstract：PURPOSE:To compare the pregnancy outcomes between women who were treated with cold-coagulation versus large loop excision of the transformation zone (LLETZ) for cervical intraepithelial neoplasia. METHODS:This was a retrospective cohort study of women who had a single cervical treatment between 2010 and 2011. We ident...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-018-4704-x
更新日期：2018-04-01 00:00:00
abstract：BACKGROUND:There are many studies documenting increased prevalence of periodontal infection in women with preeclampsia. But, very few studies have attempted to establish causal relationship between the two. OBJECTIVE:To find out causal circumstantial evidence by isolating specific periodontal pathogens in oral and pla...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-011-2012-9
更新日期：2012-03-01 00:00:00
abstract：OBJECTIVES:Total parenteral nutrition (TPN) presumably benefits cancer patients although reports have disputed the significance of this nutritional intervention. We sought to compare the postoperative outcomes of ovarian cancer patients treated with either TPN or conservative management. METHODS:We retrospectively eva...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-016-4227-2
更新日期：2017-02-01 00:00:00
abstract：PURPOSE:An important factor influencing the outcome of perineal repair is the repair technique. This study was done to determine if there is a difference in post perineal repair pain scores following the use of the standard multiple-knot technique (MKT) of perineal repair and a single-knot technique (SKT). METHODS:We ...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00404-016-4101-2
更新日期：2016-11-01 00:00:00
abstract：OBJECTIVE:To compare the efficacy and safety of fentanyl iontophoretic transdermal system (ITS) with morphine intravenous patient-controlled analgesia (IV PCA) for pain management following gynecologic surgery. METHOD:A subgroup (n = 275) of gynecologic surgery patients from a randomized study (N = 636) of patients tr...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1007/s00404-007-0339-z
更新日期：2007-09-01 00:00:00
abstract：PURPOSE:Recent evidence suggests that ADP-ribosylation factor-like tumor suppressor gene 1(ARLTS1) may act as a tumor suppressor gene. However, its role in tumor chemotherapy remains unclear. The aim of this study is to investigate the effects of ARLTS1 gene in regulation of chemosensitivity in ovarian cystadenocarcino...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-010-1782-9
更新日期：2011-11-01 00:00:00
abstract：OBJECTIVE:The objective was to characterize postmenopausal women with endometrial polyps and to evaluate their significance. METHODS:The study population included all consecutive postmenopausal patients with a diagnosis of endometrial polyps. Demographic, medical and gynecological data were assessed with regard to the...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-002-0471-8
更新日期：2004-07-01 00:00:00
abstract：PURPOSE:We sought to investigate the serum levels of asymmetric dimethylarginine in pregnant women with hyperemesis gravidarum. METHODS:Thirty-seven patients with hyperemesis gravidarum and 33 healthy controls were included in the study. Participants in the control group had no symptoms, or suffered only mild nausea w...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-011-1982-y
更新日期：2012-02-01 00:00:00
abstract：BACKGROUND:Reactive oxygen species (ROS) are an array of molecules including oxygen-centered radicals, which are endowed with one or more unpaired electrons and non-radical oxygen derivatives such as hydrogen peroxide, which behave, to a large extent, like a double-edged sword in human sperm biology. This study aimed t...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章,评审
doi：10.1007/s00404-013-2801-4
更新日期：2013-07-01 00:00:00
abstract：PURPOSE:To evaluate the efficacy and toxicity of angiogenesis inhibitors for the treatment of ovarian cancer patients, we conducted a meta-analysis of the published literature on this subject. METHODS:In this meta-analysis, we searched PubMed, EMBASE, Web of Science, and Cochrane Library databases for randomized contr...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章,评审
doi：10.1007/s00404-020-05865-z
更新日期：2020-11-21 00:00:00
abstract：PURPOSE:Serum anti-Mullerian hormone shows a strong positive correlation to the quantitative ovarian reserve but its correlation to embryo quality is unclear. This study assessed the association between serum AMH as a marker of ovarian reserve and embryo quality, using the technology of time-lapse imaging of the embryo...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-017-4453-2
更新日期：2017-09-01 00:00:00
