Abstract：
PURPOSE:More than 370 million women will experience recurrent vulvovaginal candidiasis (RVVC) during their lifetime. However, RVVC is often trivialized as clinically insignificant and not worthy of research funding. We evaluated the influence of RVVC on the quality of life in affected women. METHODS:The validated World Health Organization Quality of Life Abbreviated Assessment (WHOQOL-Bref) questionnaire was administered to 100 women with RVVC and to 101 epidemiologically matched women with no history of vulvovaginal candidiasis. RVVC was defined as at least four episodes of clinical and culture-positive vaginal candidiasis within a 1 year period. Data were analyzed by Chi square, Student t test and analysis of variance. Internal consistency of responses to questions was evaluated by Cronbach alpha. RESULTS:The Cronbach alpha coefficient was > 0.80 for responses to generalized questions and > 0.65 for answers to more specific questions, indicating substantial internal consistency. Perception of quality of life and satisfaction with their health was greatly reduced in the RVVC group (p < 0.001). Diminished responses to physical and psychological well-being were also reported by women with RVVC (p < 0.001). Various aspects of social relations including sexual activity were similarly reduced (p < 0.001) as were satisfaction with issues such as home environment, financial resources and employment (p < 0.001). CONCLUSION:RVVC affects multiple aspects of a woman's well-being. Women with this condition deserve serious attention from clinicians and research into susceptibility, prevention and treatment of this infection deserves much greater emphasis.
journal_name
Arch Gynecol Obstetjournal_title
Archives of gynecology and obstetricsauthors
Fukazawa EI,Witkin SS,Robial R,Vinagre JG,Baracat EC,Linhares IMdoi
10.1007/s00404-019-05228-3subject
Has Abstractpub_date
2019-09-01 00:00:00pages
647-650issue
3eissn
0932-0067issn
1432-0711pii
10.1007/s00404-019-05228-3journal_volume
300pub_type
杂志文章abstract：PURPOSE:To evaluate the benefits of LT4 treatment on pregnancy outcomes in SCH women. STUDY DESIGN:PubMed [including Medline], Web of Science, Wiley, Google Scholar, Science direct and Scopus were searched for identifying and retrieving all English articles published up to May 2018 on the effects of levothyroxine trea...
journal_title：Archives of gynecology and obstetrics
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