Abstract:
:Knowledge about the human skin mechanical properties is essential in several domains, particularly for dermatology, cosmetic or to detect some cutaneous pathology. This study proposes a new method to determine the human skin mechanical properties in vivo using the indentation test. Usually, the skin mechanical parameters obtained with this method are influenced by the mechanical properties of the subcutaneous layers, like muscles. In this study, different mechanical models were used to evaluate the effect of the subcutaneous layers on the measurements and to extract the skin elastic properties from the global mechanical response. The obtained results demonstrate that it is necessary to take into account the effect of the subcutaneous layers to correctly estimate the skin Young's modulus. Moreover, the results illustrate that the variation of the measured Young's modulus at low penetration depth cannot be correctly described with usual one-layer mechanical models. Thus a two-layer elastic model was proposed, which highly improved the measurement of the skin mechanical properties.
journal_name
Med Eng Physjournal_title
Medical engineering & physicsauthors
Pailler-Mattei C,Bec S,Zahouani Hdoi
10.1016/j.medengphy.2007.06.011subject
Has Abstractpub_date
2008-06-01 00:00:00pages
599-606issue
5eissn
1350-4533issn
1873-4030pii
S1350-4533(07)00135-Xjournal_volume
30pub_type
杂志文章abstract::A novel multi-scale simulation method developed to describe mesoscale phenomena occurring in biofluidic devices is presented. The approach combines the macro-scale modelling of the carrier fluid and the micro-scale description of the transported macromolecules or compounds. Application of the approach is demonstrated ...
journal_title:Medical engineering & physics
pub_type: 杂志文章
doi:10.1016/j.medengphy.2010.08.003
更新日期:2011-09-01 00:00:00
abstract::Whereas left ventricular assist device (LVAD) is the gold-standard therapy for patients with heart failure, gastrointestinal bleeding is one of the most common complications. LVAD implantation may remarkably impact aortic hemodynamics so that experimental and computational flow analyses can be used to study the diseas...
journal_title:Medical engineering & physics
pub_type: 杂志文章
doi:10.1016/j.medengphy.2017.06.029
更新日期:2017-09-01 00:00:00
abstract::The majority of the eye models developed in the late 90s and early 00s considers only heat conduction inside the eye. This assumption is not entirely correct, since the anterior and posterior chambers are filled aqueous humor (AH) that is constantly in motion due to thermally-induced buoyancy. In this paper, a three-d...
journal_title:Medical engineering & physics
pub_type: 杂志文章
doi:10.1016/j.medengphy.2016.05.011
更新日期:2016-08-01 00:00:00
abstract::The objective of this study is to determine the three dimensional kinematics of the human pelvis including both sacroiliac joints following a simulated open book injury induced on cadavers by applying anterior-posterior compressive loads to the pelvis. An electromagnetic digitizing and motion tracking system was utili...
journal_title:Medical engineering & physics
pub_type: 杂志文章
doi:10.1016/s1350-4533(02)00196-0
更新日期:2003-05-01 00:00:00
abstract::This paper describes a novel three-wire thermal flow sensor for medical applications. The present innovation for low-frequency measurements involves the use of a pulsed-wire anemometer with a comparatively large wire diameter (12.5 microm and larger) together with a novel signal processing approach. A small wire is he...
journal_title:Medical engineering & physics
pub_type: 杂志文章
doi:10.1016/j.medengphy.2004.06.002
更新日期:2004-10-01 00:00:00
abstract::The purpose of this study was to determine the accuracy of a radiographic model-based tracking technique that measures the three-dimensional in vivo motion of the tibio-femoral joint during running. Tantalum beads were implanted into the femur and tibia of three subjects and computed tomography (CT) scans were acquire...
journal_title:Medical engineering & physics
pub_type: 临床试验,杂志文章
doi:10.1016/j.medengphy.2008.03.003
更新日期:2009-01-01 00:00:00
abstract::This work proposes the use of miniature wireless inertial sensors as an objective tool for the diagnosis of ADHD. The sensors, consisting of both accelerometers and gyroscopes to measure linear and rotational movement, respectively, are used to characterize the motion of subjects in the setting of a psychiatric consul...
journal_title:Medical engineering & physics
pub_type: 杂志文章
doi:10.1016/j.medengphy.2014.02.023
更新日期:2014-07-01 00:00:00
abstract::Clinical studies show that non-invasive respiratory support by continuous positive airway pressure (CPAP) affects gas conditioning in the upper airways, especially in the presence of mouth leaks. Using a new bench model of neonatal CPAP, we investigated the influence of mouth opening on oropharyngeal temperature and h...
journal_title:Medical engineering & physics
pub_type: 杂志文章
doi:10.1016/j.medengphy.2016.12.005
更新日期:2017-02-01 00:00:00
abstract::Understanding morphological features that characterize normal hip joint is critical and necessary for a more comprehensive definition of pathological presentations, such as femoroacetabular impingement and hip dysplasia. Based on anatomical observations that articular surfaces of synovial joints are better represented...
journal_title:Medical engineering & physics
pub_type: 杂志文章
doi:10.1016/j.medengphy.2018.07.001
更新日期:2018-09-01 00:00:00
abstract::This study relates to eye fixation systems with combined optical and audio systems. Many devices for eye diagnostics and some devices for eye therapeutics require the patient to fixate on a small target for a certain period of time, during which the eyes do not move and data from substructures of one or both eyes are ...
journal_title:Medical engineering & physics
pub_type: 杂志文章
doi:10.1016/j.medengphy.2016.05.004
更新日期:2016-08-01 00:00:00
abstract::A numerical model was developed to predict the dynamics of a solid particle in a poststenotic blood vessel region. The flow through a 3D axisymmetric stenosis with 75% reduction in cross-section area was considered for inlet Reynolds numbers of 500 and 1000, which corresponds to typical values for the blood flow in hu...
journal_title:Medical engineering & physics
pub_type: 杂志文章
doi:10.1016/j.medengphy.2011.11.003
更新日期:2012-09-01 00:00:00
abstract::Schlemm's canal (SC) is a ring structure responsible for maintaining fluid homeostasis in the anterior chamber of the eye by draining aqueous humor (AH) from the trabecular meshwork (TM) into the collecting channel (CC). Obstruction of the AH flow in this conventional pathway leads to an elevation of intraocular press...
journal_title:Medical engineering & physics
pub_type: 杂志文章
doi:10.1016/j.medengphy.2020.12.005
更新日期:2021-02-01 00:00:00
abstract::Tripolar systems have been implanted to reduce the risk of recurrent dislocation. However, there is little known about the dynamic behavior of tripolar hip endoprostheses under daily life conditions and achieved joint stability. Hence, the objective of this biomechanical study was to examine the in vivo dynamics and d...
journal_title:Medical engineering & physics
pub_type: 杂志文章
doi:10.1016/j.medengphy.2013.09.007
更新日期:2014-01-01 00:00:00
abstract::A through-water ultrasonic data telemetry system using burst-mode frequency shift keying (FSK) is described. The system can be adapted for the transmission of data from various sensors, but it has been designed principally for monitoring the respiratory rate, heart rate, temperature and depth of a free-swimming diver ...
journal_title:Medical engineering & physics
pub_type: 临床试验,杂志文章
doi:10.1016/1350-4533(94)90051-5
更新日期:1994-07-01 00:00:00
abstract::Functional Electrical Stimulation (FES) is a well known clinical rehabilitation procedure, however the neural mechanisms that underlie this treatment at Central Nervous System (CNS) level are still not completely understood. Functional magnetic resonance imaging (fMRI) is a suitable tool to investigate effects of reha...
journal_title:Medical engineering & physics
pub_type: 杂志文章
doi:10.1016/j.medengphy.2011.04.005
更新日期:2011-10-01 00:00:00
abstract::The aim of this study was to develop a technique for analyzing and visualizing the regional, three-dimensional signal intensity distribution of articular cartilage in MR images, as a potential surrogate marker of structural or biochemical alterations in early osteoarthritis. Exemplary MR-images of human patellae were ...
journal_title:Medical engineering & physics
pub_type: 杂志文章
doi:10.1016/s1350-4533(02)00006-1
更新日期:2002-04-01 00:00:00
abstract::The formation of pressure ulcers can be exacerbated by a breakdown in the integrity of the patient's skin caused by poor maintenance of the skin microclimate. Patient support systems (PSSs-specialised beds, mattresses, chairs, cushions and pads) play an important role in the dissipation of heat and moisture away from ...
journal_title:Medical engineering & physics
pub_type: 杂志文章
doi:10.1016/s1350-4533(00)00003-5
更新日期:1999-12-01 00:00:00
abstract::Understanding the load mechanics of orthopaedic implants is important to be able to predict their behaviour in-vivo. Much research, both mechanical and clinical, has been carried out on hip and knee implants, but less has been written about the mechanics of wrist implants. In this paper, the load mechanics of the Univ...
journal_title:Medical engineering & physics
pub_type: 杂志文章
doi:10.1016/j.medengphy.2016.02.008
更新日期:2016-06-01 00:00:00
abstract::Investigations focused on the gait and physiological limits of human speed have been on-going for more than a century. However, due to measurement limitation a kinetic understanding of the foot-ground collision and how these dynamics differ between individuals to confer speed and limit gait has only recently begun to ...
journal_title:Medical engineering & physics
pub_type: 杂志文章
doi:10.1016/j.medengphy.2015.04.009
更新日期:2015-09-01 00:00:00
abstract::Zygomatic implant technology has been regarded as an alternative treatment to massive grafting surgery in the severe atrophic maxillary. Nowadays, the assistant method with a real-time surgical navigation has been applied to reduce the risks of zygomatic implant placement. However, the accuracy of the complex operatio...
journal_title:Medical engineering & physics
pub_type: 杂志文章
doi:10.1016/j.medengphy.2019.07.020
更新日期:2020-01-01 00:00:00
abstract::A field-usable sleepiness tester could reduce sleepiness related accidents. 15 subjects' postural steadiness was measured with a Nintendo(®) Wii Fit balance board every hour for 24 h. Body sway was quantified with complexity index, CI, and the correlation between CI and alertness predicted by a three-process model of ...
journal_title:Medical engineering & physics
pub_type: 杂志文章
doi:10.1016/j.medengphy.2013.08.007
更新日期:2013-12-01 00:00:00
abstract::Aseptic loosening is the major failure mode for hip prostheses. Currently, loosened prostheses are revised during open surgery. Because of a high complication rate, this demanding procedure cannot be performed in patients with a poor general health. We are developing an alternative minimally invasive refixation proced...
journal_title:Medical engineering & physics
pub_type: 杂志文章
doi:10.1016/j.medengphy.2011.07.029
更新日期:2012-04-01 00:00:00
abstract::A ligamentous, nonlinear, sliding contact, three-dimensional finite element (FE) model of L2-L3 complex was developed to investigate the biomechanical effect of laminectomy with and without facetectomy. The L2-L3 FE model was validated against experimental study under various physiological loadings and found to match ...
journal_title:Medical engineering & physics
pub_type: 杂志文章
doi:10.1016/j.medengphy.2003.11.006
更新日期:2004-04-01 00:00:00
abstract::The investigation presented in this paper has attempted to study, from a fluid dynamics point of view, the consequences of the presence of a stent on the flow of blood. The method adopted is mainly by numerical simulation using a finite element technique, but visualization experiments and an analytical study have also...
journal_title:Medical engineering & physics
pub_type: 杂志文章
doi:10.1016/s1350-4533(00)00072-2
更新日期:2000-10-01 00:00:00
abstract::Functional spinal units (FSUs) are frequently used for in vitro mechanical testing. This approach assumes that the mechanical behavior of the FSUs is equivalent to the mechanics of these segments within the intact spine. The purpose of this study was to determine whether normal spinal mechanics are compromised in FSU ...
journal_title:Medical engineering & physics
pub_type: 杂志文章
doi:10.1016/s1350-4533(02)00152-2
更新日期:2003-04-01 00:00:00
abstract:BACKGROUND:Verified and validated CT-based high-order finite element (FE) methods were developed that predict accurately the mechanical response of patient-specific intact femurs. Here we extend these capabilities to human femurs undergoing a total hip replacement using cemented prostheses. METHODS:A fresh-frozen huma...
journal_title:Medical engineering & physics
pub_type: 杂志文章
doi:10.1016/j.medengphy.2012.09.007
更新日期:2013-07-01 00:00:00
abstract::Understanding hip osteoarthritis requires new investigational tools for quantitative studies of biophysical and biomechanical properties as well as for determination of structure. Three new protocols to study pathological changes in cartilage and to measure cartilage thickness in intact human hips are described using ...
journal_title:Medical engineering & physics
pub_type: 杂志文章
doi:10.1016/j.medengphy.2019.08.003
更新日期:2019-11-01 00:00:00
abstract::This work compared the performance of six different fatigue detection algorithms quantifying muscle fatigue based on electromyographic signals. Surface electromyography (sEMG) was obtained by an experiment from upper arm contractions at three different load levels from twelve volunteers. Fatigue detection algorithms m...
journal_title:Medical engineering & physics
pub_type: 杂志文章
doi:10.1016/j.medengphy.2016.09.009
更新日期:2016-11-01 00:00:00
abstract::Gastric contractions play an important role in the digestive process of the stomach. The established method for the measurement of gastric contractions is invasive and involves the insertion through the nose of a manometric probe into the stomach. A non-invasive method is introduced in this paper for the identificatio...
journal_title:Medical engineering & physics
pub_type: 杂志文章
doi:10.1016/1350-4533(95)95713-k
更新日期:1995-04-01 00:00:00
abstract::The paper described a limited part of the coagulation pathway, and in particular the inhibitory effects of activated protein C in the context of thrombin production. This is a computational modeling study with various assumption made of kinetic rates laws and their summation. The level of complexity and assumed parame...
journal_title:Medical engineering & physics
pub_type: 杂志文章
doi:10.1016/j.medengphy.2004.01.003
更新日期:2004-05-01 00:00:00