Abstract:
:Four allelic forms of serum plasminogen (PLG) were detected in baboons (Papio hamadryas Linneaus 1758) by isoelectric focusing and were determined to be inherited as autosomal codominant traits. Linkage analysis of data from 179 progeny and their parents revealed that PLG is tightly linked (lod score = 30.20) to the gene encoding apolipoprotein(a) (LPA), as in humans. No recombinant individuals were identified. This is the first linkage detected between PLG and LPA in any species other than humans and is the first genetic linkage identified in a nonhuman primate species by family studies.
journal_name
Genomicsjournal_title
Genomicsauthors
VandeBerg JL,Weitkamp L,Kammerer CM,Weill P,Aivaliotis MJ,Rainwater DLdoi
10.1016/0888-7543(91)90016-8subject
Has Abstractpub_date
1991-12-01 00:00:00pages
925-30issue
4eissn
0888-7543issn
1089-8646pii
0888-7543(91)90016-8journal_volume
11pub_type
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