Abstract：
:Although there are many algorithms available in the literature aimed at segmentation and model reconstruction of 3D angiographic images, many are focused on characterizing only a part of the vascular network. This study is motivated by the recent emerging prospects of whole-organ simulations in coronary hemodynamics, autoregulation and tissue oxygen delivery for which anatomically accurate vascular meshes of extended scale are highly desirable. The key requirements of a reconstruction technique for this purpose are automation of processing and sub-voxel accuracy. We have designed a vascular reconstruction algorithm which satisfies these two criteria. It combines automatic seeding and tracking of vessels with radius detection based on active contours. The method was first examined through a series of tests on synthetic data, for accuracy in reproduced topology and morphology of the network and was shown to exhibit errors of less than 0.5 voxel for centerline and radius detections, and 3 degrees for initial seed directions. The algorithm was then applied on real-world data of full rat coronary structure acquired using a micro-CT scanner at 20 microm voxel size. For this, a further validation of radius quantification was carried out against a partially rescanned portion of the network at 8 microm voxel size, which estimated less than 10% radius error in vessels larger than 2 voxels in radius.
journal_name
Med Image Analjournal_title
Medical image analysisauthors
Lee J,Beighley P,Ritman E,Smith Ndoi
10.1016/j.media.2007.06.012subject
Has Abstractpub_date
2007-12-01 00:00:00pages
630-47issue
6eissn
1361-8415issn
1361-8423pii
S1361-8415(07)00064-3journal_volume
11pub_type
杂志文章abstract：:Image-based parcellation of the brain often leads to multiple disconnected anatomical structures, which pose significant challenges for analyses of morphological shapes. Existing shape models, such as the widely used spherical harmonic (SPHARM) representation, assume topological invariance, so are unable to simultaneo...
journal_title：Medical image analysis
pub_type： 杂志文章
doi：10.1016/j.media.2015.02.004
更新日期：2015-05-01 00:00:00
abstract：:In this work, we first propose an original and efficient computational framework to model continuous diffusion MRI (dMRI) signals and analytically recover important diffusion features such as the Ensemble Average Propagator (EAP) and the Orientation Distribution Function (ODF). Then, we develop an efficient parametric...
journal_title：Medical image analysis
pub_type： 杂志文章
doi：10.1016/j.media.2013.04.011
更新日期：2013-10-01 00:00:00
abstract：:In this paper, we present a framework to estimate local ventricular myocardium contractility using clinical MRI, a heart model and data assimilation. First, we build a generic anatomical model of the ventricles including muscle fibre orientations and anatomical subdivisions. Then, this model is deformed to fit a clini...
journal_title：Medical image analysis
pub_type： 杂志文章
doi：10.1016/j.media.2006.04.002
更新日期：2006-08-01 00:00:00
abstract：:This paper presents a new approach for multimodal medical image registration and compares it to normalized mutual information (NMI) and the correlation ratio (CR). Like NMI and CR, the new method's measure of registration quality is based on the distribution of points in the joint intensity scatter plot (JISP); compac...
journal_title：Medical image analysis
pub_type： 杂志文章
doi：10.1016/j.media.2007.12.002
更新日期：2008-08-01 00:00:00
abstract：:Atlas-based methods for automated preoperative planning of the femoral stem implant in total hip arthroplasty are described. Statistical atlases are constructed from a number of past preoperative plans prepared by experienced surgeons in order to represent the surgeon's expertise of the planning. Two types of atlases ...
journal_title：Medical image analysis
pub_type： 杂志文章
doi：10.1016/j.media.2011.10.005
更新日期：2012-02-01 00:00:00
abstract：:In order to improve the accuracy of image-guided neurosurgery, different biomechanical models have been developed to correct preoperative images with respect to intraoperative changes like brain shift or tumor resection. All existing biomechanical models simulate different anatomical structures by using either appropr...
journal_title：Medical image analysis
pub_type： 杂志文章
doi：10.1016/s1361-8415(02)00059-2
更新日期：2002-12-01 00:00:00
abstract：:Diffusion magnetic resonance imaging (dMRI) provides a noninvasive method for measuring brain tissue microstructure. q-Space deep learning(q-DL) methods have been developed to accurately estimate tissue microstructure from dMRI scans acquired with a reduced number of diffusion gradients. In these methods, deep network...
journal_title：Medical image analysis
pub_type： 杂志文章
doi：10.1016/j.media.2020.101885
更新日期：2021-01-01 00:00:00
abstract：:Prostate brachytherapy is a treatment for prostate cancer using radioactive seeds that are permanently implanted in the prostate. The treatment success depends on adequate coverage of the target gland with a therapeutic dose, while sparing the surrounding tissue. Since seed implantation is performed under transrectal ...
journal_title：Medical image analysis
pub_type： 杂志文章
doi：10.1016/j.media.2012.06.001
更新日期：2012-10-01 00:00:00
abstract：:Although white matter hyperintensities evolve in the course of ageing, few solutions exist to consider the lesion segmentation problem longitudinally. Based on an existing automatic lesion segmentation algorithm, a longitudinal extension is proposed. For evaluation purposes, a longitudinal lesion simulator is created ...
journal_title：Medical image analysis
pub_type： 杂志文章
doi：10.1016/j.media.2017.02.007
更新日期：2017-05-01 00:00:00
abstract：:The goal of this study is to provide a theoretical framework for accurately optimizing the segmentation energy considering all of the possible shapes generated from the level-set-based statistical shape model (SSM). The proposed algorithm solves the well-known open problem, in which a shape prior may not be optimal in...
journal_title：Medical image analysis
pub_type： 杂志文章
doi：10.1016/j.media.2015.11.003
更新日期：2016-02-01 00:00:00
abstract：:This article describes a combination of interactive classification and super-sampling visualization algorithms that greatly enhances the realism of 3-D reconstructions of the Visible Human data sets. Objects are classified on the basis of ellipsoidal regions in RGB space. The ellipsoids are used for super-sampling in ...
journal_title：Medical image analysis
pub_type： 杂志文章
doi：10.1016/s1361-8415(97)85001-3
更新日期：1997-09-01 00:00:00
abstract：:This paper introduces a model-based approach for a fully automatic delineation of kidney and cortex tissue from contrast-enhanced abdominal CT scans. The proposed framework, named CorteXpert, consists of two new strategies for kidney tissue delineation: cortex model adaptation and non-uniform graph search. CorteXpert ...
journal_title：Medical image analysis
pub_type： 杂志文章
doi：10.1016/j.media.2017.06.010
更新日期：2017-12-01 00:00:00
abstract：:Pseudo-healthy synthesis is the task of creating a subject-specific 'healthy' image from a pathological one. Such images can be helpful in tasks such as anomaly detection and understanding changes induced by pathology and disease. In this paper, we present a model that is encouraged to disentangle the information of p...
journal_title：Medical image analysis
pub_type： 杂志文章
doi：10.1016/j.media.2020.101719
更新日期：2020-08-01 00:00:00
abstract：:In this paper, we exploit the ability of Compressed Sensing (CS) to recover the whole 3D Diffusion MRI (dMRI) signal from a limited number of samples while efficiently recovering important diffusion features such as the Ensemble Average Propagator (EAP) and the Orientation Distribution Function (ODF). Some attempts to...
journal_title：Medical image analysis
pub_type： 杂志文章
doi：10.1016/j.media.2013.02.010
更新日期：2013-07-01 00:00:00
abstract：:We propose a novel Riemannian framework for statistical analysis of shapes that is able to account for the nonlinearity in shape variation. By adopting a physical perspective, we introduce a differential representation that puts the local geometric variability into focus. We model these differential coordinates as ele...
journal_title：Medical image analysis
pub_type： 杂志文章
doi：10.1016/j.media.2017.09.004
更新日期：2018-01-01 00:00:00
abstract：:In this paper an automatic atlas-based segmentation algorithm for 4D cardiac MR images is proposed. The algorithm is based on the 4D extension of the expectation maximisation (EM) algorithm. The EM algorithm uses a 4D probabilistic cardiac atlas to estimate the initial model parameters and to integrate a priori inform...
journal_title：Medical image analysis
pub_type： 杂志文章
doi：10.1016/j.media.2004.06.005
更新日期：2004-09-01 00:00:00
abstract：:We describe a new algorithm for non-rigid registration capable of estimating a constrained dense displacement field from multi-modal image data. We applied this algorithm to capture non-rigid deformation between digital images of histological slides and digital flat-bed scanned images of cryotomed sections of the lary...
journal_title：Medical image analysis
pub_type： 杂志文章
doi：10.1016/j.media.2005.04.003
更新日期：2005-12-01 00:00:00
abstract：:Traditionally, segmentation and registration have been solved as two independent problems, even though it is often the case that the solution to one impacts the solution to the other. In this paper, we introduce a geometric, variational framework that uses active contours to simultaneously segment and register feature...
journal_title：Medical image analysis
pub_type： 杂志文章
doi：10.1016/s1361-8415(03)00004-5
更新日期：2003-06-01 00:00:00
abstract：:Real-time cardiac MRI appears as a promising technique to evaluate the mechanical function of the heart. However, ultra-fast MRI acquisitions come with an important signal-to-noise ratio (SNR) penalty, which drastically reduces the image quality. Hence, a real-time denoising approach would be desirable for SNR amelior...
journal_title：Medical image analysis
pub_type： 杂志文章
doi：10.1016/j.media.2009.05.006
更新日期：2009-08-01 00:00:00
abstract：:Current neuroimaging investigation of the white matter typically focuses on measurements derived from diffusion tensor imaging, such as fractional anisotropy (FA). In contrast, imaging studies of the gray matter oftentimes focus on morphological features such as cortical thickness, folding and surface curvature. As a ...
journal_title：Medical image analysis
pub_type： 杂志文章
doi：10.1016/j.media.2014.06.013
更新日期：2014-12-01 00:00:00
abstract：:Many cardiac pathologies are reflected in abnormal myocardial deformation, accessible through magnetic resonance tagging (MRT). Interpretation of the MRT data is difficult, since the relation between pathology and deformation is not straightforward. Mathematical models of cardiac mechanics could be used to translate m...
journal_title：Medical image analysis
pub_type： 杂志文章
doi：10.1016/j.media.2006.04.001
更新日期：2006-08-01 00:00:00
abstract：:We describe a new 3-D statistical shape model of the heart consisting of atria, ventricles and epicardium. The model was constructed by combining information on standard short- and long-axis cardiac MR images. In the model, the variability of the shape was modeled with PCA- and ICA-based shape models as well as with n...
journal_title：Medical image analysis
pub_type： 杂志文章
doi：10.1016/j.media.2004.06.013
更新日期：2004-09-01 00:00:00
abstract：:Synthesized medical images have several important applications. For instance, they can be used as an intermedium in cross-modality image registration or used as augmented training samples to boost the generalization capability of a classifier. In this work, we propose a generic cross-modality synthesis approach with t...
journal_title：Medical image analysis
pub_type： 杂志文章
doi：10.1016/j.media.2018.12.002
更新日期：2019-02-01 00:00:00
abstract：:In this paper, we present a graph-based concurrent brain tumor segmentation and atlas to diseased patient registration framework. Both segmentation and registration problems are modeled using a unified pairwise discrete Markov Random Field model on a sparse grid superimposed to the image domain. Segmentation is addres...
journal_title：Medical image analysis
pub_type： 杂志文章
doi：10.1016/j.media.2014.02.006
更新日期：2014-05-01 00:00:00
abstract：:A new information-theoretic approach is presented for finding the registration of volumetric medical images of differing modalities. Registration is achieved by adjustment of the relative position and orientation until the mutual information between the images is maximized. In our derivation of the registration proced...
journal_title：Medical image analysis
pub_type： 杂志文章
doi：10.1016/s1361-8415(01)80004-9
更新日期：1996-03-01 00:00:00
abstract：:During embryogenesis, a mammalian heart develops from a simple tubular shape into a complex 4-chamber organ, going through four distinct phases: early primitive tubular heart, emergence of trabeculations, trabecular remodeling and development of the compact myocardium. In this paper we propose a framework for standard...
journal_title：Medical image analysis
pub_type： 杂志文章
doi：10.1016/j.media.2018.08.001
更新日期：2018-10-01 00:00:00
abstract：:A number of algorithms for brain segmentation in preterm born infants have been published, but a reliable comparison of their performance is lacking. The NeoBrainS12 study (http://neobrains12.isi.uu.nl), providing three different image sets of preterm born infants, was set up to provide such a comparison. These sets a...
journal_title：Medical image analysis
pub_type： 杂志文章
doi：10.1016/j.media.2014.11.001
更新日期：2015-02-01 00:00:00
abstract：:Robust and fast detection of anatomical structures represents an important component of medical image analysis technologies. Current solutions for anatomy detection are based on machine learning, and are generally driven by suboptimal and exhaustive search strategies. In particular, these techniques do not effectively...
journal_title：Medical image analysis
pub_type： 杂志文章
doi：10.1016/j.media.2018.06.007
更新日期：2018-08-01 00:00:00
abstract：:The problem of respiratory motion has proved a serious obstacle in developing techniques to acquire images or guide interventions in abdominal and thoracic organs. Motion models offer a possible solution to these problems, and as a result the field of respiratory motion modelling has become an active one over the past...
journal_title：Medical image analysis
pub_type： 杂志文章,评审
doi：10.1016/j.media.2012.09.005
更新日期：2013-01-01 00:00:00
abstract：:Retinal images are routinely acquired and assessed to provide diagnostic evidence for many important diseases, e.g. diabetes or hypertension. Because of the acquisition process, very often these images are non-uniformly illuminated and exhibit local luminosity and contrast variability. This problem may seriously affec...
journal_title：Medical image analysis
pub_type： 杂志文章
doi：10.1016/j.media.2004.07.001
更新日期：2005-06-01 00:00:00
