Abstract:
:In this work, we first propose an original and efficient computational framework to model continuous diffusion MRI (dMRI) signals and analytically recover important diffusion features such as the Ensemble Average Propagator (EAP) and the Orientation Distribution Function (ODF). Then, we develop an efficient parametric dictionary learning algorithm and exploit the sparse property of a well-designed dictionary to recover the diffusion signal and its features with a reduced number of measurements. The properties and potentials of the technique are demonstrated using various simulations on synthetic data and on human brain data acquired from 7T and 3T scanners. It is shown that the technique can clearly recover the dMRI signal and its features with a much better accuracy compared to state-of-the-art approaches, even with a small and reduced number of measurements. In particular, we can accurately recover the ODF in regions of multiple fiber crossing, which could open new perspectives for some dMRI applications such as fiber tractography.
journal_name
Med Image Analjournal_title
Medical image analysisauthors
Merlet S,Caruyer E,Ghosh A,Deriche Rdoi
10.1016/j.media.2013.04.011subject
Has Abstractpub_date
2013-10-01 00:00:00pages
830-43issue
7eissn
1361-8415issn
1361-8423pii
S1361-8415(13)00064-9journal_volume
17pub_type
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