Adaptive local window for level set segmentation of CT and MRI liver lesions.

Abstract:

:We propose a novel method, the adaptive local window, for improving level set segmentation technique. The window is estimated separately for each contour point, over iterations of the segmentation process, and for each individual object. Our method considers the object scale, the spatial texture, and the changes of the energy functional over iterations. Global and local statistics are considered by calculating several gray level co-occurrence matrices. We demonstrate the capabilities of the method in the domain of medical imaging for segmenting 233 images with liver lesions. To illustrate the strength of our method, those lesions were screened by either Computed Tomography or Magnetic Resonance Imaging. Moreover, we analyzed images using three different energy models. We compared our method to a global level set segmentation, to a local framework that uses predefined fixed-size square windows and to a local region-scalable fitting model. The results indicate that our proposed method outperforms the other methods in terms of agreement with the manual marking and dependence on contour initialization or the energy model used. In case of complex lesions, such as low contrast lesions, heterogeneous lesions, or lesions with a noisy background, our method shows significantly better segmentation with an improvement of 0.25 ± 0.13 in Dice similarity coefficient, compared with state of the art fixed-size local windows (Wilcoxon, p < 0.001).

journal_name

Med Image Anal

journal_title

Medical image analysis

authors

Hoogi A,Beaulieu CF,Cunha GM,Heba E,Sirlin CB,Napel S,Rubin DL

doi

10.1016/j.media.2017.01.002

subject

Has Abstract

pub_date

2017-04-01 00:00:00

pages

46-55

eissn

1361-8415

issn

1361-8423

pii

S1361-8415(17)30010-5

journal_volume

37

pub_type

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