Prescribing pattern in a Dutch university hospital.

abstract：WHAT IS KNOWN AND OBJECTIVE:Carbamazepine is a potent inducer of cytochrome P450 3A and P-glycoprotein. However, there are no reports of the effects of carbamazepine on more than one co-administered drug. CASE SUMMARY:A 53-year-old female patient with schizophrenia and hypertension was on paliperidone 12 mg/day and am...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Akamine Y,Uehara H,Miura M,Yasui-Furukori N,Uno T

更新日期：2015-08-01 00:00:00

abstract：:Recent reports of interactions between alcohol and benzodiazepines, tricyclic and tetracyclic antidepressants during their acute concomitant use are reviewed. Acute ingestion of alcohol (ethanol) with tranquilizers or hypnotics is responsible for several pharmacokinetic interactions that can have significant clinical ...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Tanaka E,Misawa S

更新日期：1998-10-01 00:00:00

abstract：:The bioequivalence of a 600-mg methocel tablet containing buflomedil hydrochloride in sustained-release form was determined relative to a 300-mg CAP/carbovax-coated tablet of buflomedil hydrochloride in immediate-release form. The tablets were given to 20 patients in a double-blind placebo-controlled clinical study wi...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Molinaro M,Regazzi MB,Raffaghello S,Buggia I,Iacona I,Graziani P,Specchia G,Melzi D'eril G

更新日期：1994-04-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Midazolam (MDZ) is commonly used for sedating critically ill patients. The daily dose required for adequate sedation increases in increments over 100 h after administration. The objectives of this study were to characterize the MDZ pharmacokinetics in critically ill patients and to describe ...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Aoyama T,Hirata K,Yamamoto Y,Yokota H,Hayashi H,Aoyama Y,Matsumoto Y

更新日期：2016-08-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Computerized physician order entry (CPOE) systems reduce medical errors (MEs). Nevertheless, a CPOE system may also lead to new types of errors, especially when it is first implemented. The objectives of this study were to determine the impact of a CPOE on the number of MEs and to identify t...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Sanchez Cuervo M,Rojo Sanchis A,Pueyo Lopez C,Gomez de Salazar Lopez de Silanes E,Gramage Caro T,Bermejo Vicedo T

更新日期：2015-10-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Lactic acidosis (LA) is a rare but potentially lethal side effect of linezolid (LZD). However, limited by the study population, the number of patients with LA is insufficient to summarize all the clinical characteristics and risk factors. METHODS:We evaluated the association between LZD and...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Dai Y,Wang Y,Zeng Y,Zhang C,Zhou Z,Shi D

更新日期：2020-12-01 00:00:00

abstract：:Isradipine is a potent dihydropyridine calcium channel blocker. It is highly selective for vascular smooth muscle, with very few negative inotropic or chronotropic effects. It may have minor depressant effects on the sinoatrial node, hence reducing the incidence of reflex tachycardia. The drug is extensively metaboliz...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Schachter M

更新日期：1991-04-01 00:00:00

abstract：:Drug-induced parotitis is a relatively uncommon adverse drug reaction. Most of the data on drug-induced parotitis consist of isolated case reports with few attempts at rechallenge to confirm the aetiology. Phenylbutazone and oxyphenbutazone have a significant number of reports suggesting that these drugs may be implic...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Thompson DF

更新日期：1993-08-01 00:00:00

abstract：OBJECTIVE:To assess the usefulness of dynamic laser scattering for monitoring the stability of ampicillin after reconstitution from commercially available vials with respect to the polymer formation and potency. METHODS:Polymer formation and the remaining potency of the reconstituted ampicillin solution were estimated...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Sendo T,Teshima D,Makino K,Mishima K,Itoh Y,Oishi R

更新日期：2002-04-01 00:00:00

abstract：OBJECTIVE:To evaluate the usefulness of intervention in drug interactions of antiretroviral drugs with coadministered agents by a clinical pharmacist in outpatient HIV-treatment. METHODS:The study design included two intervention arms (A and B), which were both preceded by a control observation period. In arm A, a com...

journal_title：Journal of clinical pharmacy and therapeutics

authors： de Maat MM,de Boer A,Koks CH,Mulder JW,Meenhorst PL,van Gorp EC,Mairuhu AT,Huitema AD,Beijnen JH

更新日期：2004-04-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Clinical use of fluconazole against fungal infections in renal transplant patients is complicated by the potentially marked and unpredictable drug-drug interactions (DDIs). We report a case of tacrolimus-fluconazole DDI in a stable renal transplant recipient and describe the mechanism, magni...

journal_title：Journal of clinical pharmacy and therapeutics

authors： He J,Yu Y,Yin C,Liu H,Zou H,Ma J,Yang W,Liu Y,Zhong L,Chen X

更新日期：2020-04-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Glucocorticoid-induced diabetes mellitus (GIDM) increases the risk of diabetes mellitus (DM)-related complications but is generally difficult to detect in clinical settings. The criteria for diagnosing GIDM have not been established. Recently, medical information databases (MIDs) have been u...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Imatoh T,Sai K,Hori K,Segawa K,Kawakami J,Kimura M,Saito Y

更新日期：2017-04-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Moringa oleifera (MO) Lam (Moringaceae) is commonly used as food supplement and as medicine in most African countries where malaria is also endemic. Therefore, co-administration of MO with antimalarials is a possibility. This study investigated the effects of MO leaves powder on the pharmaco...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Olawoye OS,Adeagbo BA,Bolaji OO

更新日期：2018-10-01 00:00:00

abstract：:This study investigated chemical and pharmaceutical equivalence of 11 brands of pyrimethamine-sulphadoxine combination tablets sold on the Tanzanian market. Physical and chemical tests were performed for all the 11 brands. These tests included hardness test, friability, disintegration, dissolution, weight uniformity a...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Hebron Y,Tettey JN,Pournamdari M,Watson DG

更新日期：2005-12-01 00:00:00

abstract：:The stability and compatibility of anakinra (recombinant human interleukin-1 receptor antagonist) with ceftriaxone sodium in 0.9% sodium chloride or 5% dextrose injection was determined during a 4-h period at ambient room temperature and light. Anakinra was diluted in 0.9% sodium chloride or 5% dextrose to the concent...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Nahata MC,Morosco RS,Sabados BK,Weber TR

更新日期：1997-06-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Current guidelines recommend a combination of clopidogrel and aspirin for management of patients who have experienced an acute coronary syndrome (ACS). Additional antiplatelet agents have been recently approved. Few comparative effectiveness studies are available for these new agents. Accord...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Olson WH,Ma YW,Laliberté F,Lefebvre P,Crivera C,Schein JR,Fields LE,Dea K,Germain G,Lynch SM

更新日期：2014-12-01 00:00:00

abstract：:This study involved the mixing of 1:1 combinations of Bactroban (mupirocin) Ointment 2% with various cream, lotion, ointment, gel, solution and liquid soap formulations with storage at 37 degrees C for 60 days. The mixtures were assayed for mupirocin content at 0, 15, 30, 45 and 60 days using a high-pressure liquid ch...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Jagota NK,Stewart JT,Warren FW,John PM

更新日期：1992-06-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:There are no clinical reports that have compared topiroxostat, a selective xanthine oxidase inhibitor, with allopurinol in serum urate-lowering efficacy. The aim of this study was to compare the efficacy and safety of topiroxostat and allopurinol in Japanese hyperuricemic patients with or wi...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Hosoya T,Ogawa Y,Hashimoto H,Ohashi T,Sakamoto R

更新日期：2016-06-01 00:00:00

abstract：:Nineteen different brands of topical creams were tested in duplicate for microbial growth. The efficacy of their preservation was assessed, when possible, by standard pharmacopoeial procedures. Microbial growth was demonstrated in cultures from all specimens. However, high counts (> 10(4) c.f.u./g) were obtained from ...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Na'was T,Alkofahi A

更新日期：1994-02-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:To assess the equivalent efficacy of two or more treatments, clinical relevance must be adequately established, but there appears to be some confusion between clinical relevance and differences in absolute risk reduction or effect size, which quantifies the size of the difference between two...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Puig L

更新日期：2015-04-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Imatinib mesylate (IM) is the first-line therapy for unresectable or metastatic gastrointestinal stromal tumours (GISTs). Here, we report a case of successful progressive dose optimization by therapeutic drug monitoring (TDM) for a patient with GISTs who developed IM-associated serious cutan...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Huang W,Li J,Qiu F,Wu X,Zhang J,Li X,Yao G,Zhu S

更新日期：2020-08-01 00:00:00

abstract：OBJECTIVE:To investigate the effect of the reconstitution methods for the commercial amphotericin B preparation with respect to particulate contamination. METHODS:The particle counts in amphotericin B solutions reconstituted according to three different methods and amphotericin B fluids made with intravenous fluids af...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Sendo T,Hirakawa M,Makino K,Nakashima K,Kataoka Y,Oishi R

更新日期：2001-04-01 00:00:00

abstract：OBJECTIVES:The use of psychotropic drugs has increased continuously over recent years in industrialized countries. In Europe, France has the highest consumption of such drugs. The aim of this study was to identify the sociodemographic and medical factors associated with the use of psychotropic agents. METHODS:Data, co...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Empereur F,Baumann M,Alla F,Briançon S

更新日期：2003-02-01 00:00:00

abstract：:Graft patency is a major factor contributing to the long-term results of coronary artery bypass graft (CABG) surgery. The systematic overview of the Antiplatelet Trialists' Collaboration provides unequivocal evidence that antiplatelet therapy reduces by nearly one-half the odds of coronary graft occlusion following CA...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Galea J,Manché A,Goiti JJ,Locke TJ,Wilkinson GA,Smith GH

更新日期：1994-12-01 00:00:00

abstract：:Antimicrobials are frequently used to prevent infections. Principles of prophylaxis, and antimicrobial prophylaxis in surgery, tuberculosis, acquired immunodeficiency syndrome, influenza A, traveller's diarrhoea, malaria, recurrent otitis media, Haemophilus influenzae type b infection, pertussis, rheumatic fever, and ...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Nahata MC

更新日期：1996-08-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Many refractory/relapsed haematological malignancies, in non-remission state, still have poor prognosis even after allogeneic haematopoietic stem cell transplantation. Recently, decitabine or umbilical cord blood transplantation (UCBT) seemed to be effective in these patients. However, few s...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Yao W,Chu X,Fang X,Zhu X,Tang B,Wan X,Geng L,Tong J,Song K,Zhang X,Qiang P,Sun G,Liu H,Sun Z

更新日期：2020-12-01 00:00:00

abstract：:A study was conducted in two groups of healthy volunteers to assess whether the time of administration (10 min before the meal versus 60 min after the meal) influences the pharmacokinetics and absorption kinetics of a slow-release theophylline product (Teonova). In the first group (Group A, n = 10), the drug was given...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Boner AL,Sette L,Messori A,Plebani M,Vallone G,Martini N

更新日期：1988-02-01 00:00:00

abstract：:A high-performance liquid chromatographic method for the analysis of ranitidine in plasma and urine is described. Plasma samples were extracted with dichloromethane while urine samples were injected directly after dilution. The mobile phase consisted of: 0.05 M ammonium acetate buffer containing 0.01 M octane sulphona...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Shiekh Salem M,Gharaibeh AM,Alkaysi HN,Badwan A

更新日期：1988-10-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Low levels of serum triiodothyronine (T3) are a strong predictor of mortality and poor prognosis in critical care patients. Few reports, however, have focused on neurocritical patients. The application of hormone replacement therapy (HRT) in the treatment of neurocritical patients with low T...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Chen Y,Chang J,Yin R,Wen J,Ma B,Zuo W,Zhang X,Wei J

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:The effects of the macrolides cannot be ascribed to their antibacterial action alone. Their immunoregulatory and anti-inflammatory functions are significant too. They are frequently used in the treatment of diffuse panbronchiolitis and cystic fibrosis (CF). AIM:To evaluate the effects of a macrolide antibio...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Yalçin E,Kiper N,Ozçelik U,Doğru D,Firat P,Sahin A,Ariyürek M,Mocan G,Gürcan N,Göçmen A

更新日期：2006-02-01 00:00:00