Drug-induced parotitis.

abstract：WHAT IS KNOWN AND OBJECTIVE:Appraisal of drug information centres (DICs) is mainly by word of mouth communication and surveys of overall user satisfaction. Efforts to study the impact of this type of informatics and decision support systematically are generally lacking within the healthcare system. COMMENT:Scandinavia...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Schjøtt J,Spigset O

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Enteric-coated, delayed-release divalproex sodium requires multiple daily administrations and high adherence rate to prevent breakthrough seizures and control adverse effects. We evaluated the effect of missing one or two doses of divalproex for up to 24 h, followed by replacement and resumptio...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Dutta S,Reed RC

更新日期：2006-08-01 00:00:00

abstract：BACKGROUND:Ropivacaine hydrochloride (HCl) ('Naropin') is a long-acting local anaesthetic agent, administered epidurally to patients undergoing various surgical procedures. A combination of local anaesthetic and opioid is often administered for the management of severe pain to ensure that a minimal dose of each is used...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Oster Svedberg K,McKenzie J,Larrivee-Elkins C

更新日期：2002-02-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Linezolid, a member of the oxazolidinone class of antibacterial drugs, is approved by the US Food and Drug Administration (FDA) for the treatment of vancomycin-resistant Enterococcus faecium infections, nosocomial and community-acquired pneumonia, as a part of anti tubercular regimen and com...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Singhania SVK,Shenoy S,Kapoor D

更新日期：2020-04-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Cytochrome P450 1A2 (CYP1A2), CYP2B6 and inducible nitric oxide synthase (iNOS) are involved in the metabolism and action of many important therapeutic drugs, and genetic variants have been associated with interethnic differences in response to treatment, including chemotherapy. METHODS:Eig...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Qi GZ,Zhang ZY,Wang X,Yin SJ,Lou YQ,Zhang GL

更新日期：2016-02-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:The most appropriate sedative agent for conscious sedation in minor hysteroscopic surgeries is still unclear. Dexmedetomidine a sedative and analgesic agent, may be appropriate for outpatient procedures. The aim of our study was to compare the sedative, analgesic and hemodynamic effects of d...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Bingol Tanriverdi T,Koceroglu I,Devrim S,Gura Celik M

更新日期：2019-04-01 00:00:00

abstract：:A study was conducted in two groups of healthy volunteers to assess whether the time of administration (10 min before the meal versus 60 min after the meal) influences the pharmacokinetics and absorption kinetics of a slow-release theophylline product (Teonova). In the first group (Group A, n = 10), the drug was given...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Boner AL,Sette L,Messori A,Plebani M,Vallone G,Martini N

更新日期：1988-02-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:There is much controversy over how angiotensin II receptor blockers (ARB) or angiotensin-converting enzyme inhibitors (ACEI) affect blood uric acid levels. Though ARB is not used to lorcwer the uric acid concentration in the blood, losartan, one of the ARB series, is known to reduce the uric...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Kim HS,Kim H,Lee SH,Kim JH

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:In September 1998, legislation was introduced in the United Kingdom to limit paracetamol pack sizes to 16 tablets of 500 mg at general sales outlets and 32 tablets of 500 mg at pharmacies. The effect of the regulations on severity of paracetamol poisoning is unclear. The aim of this study was t...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Morgan O,Hawkins L,Edwards N,Dargan P

更新日期：2007-10-01 00:00:00

abstract：:The subject of 'drug addiction' is multifaceted and many aspects of it (even some of the definitions) are controversial. Collateral medical problems include the spread of HIV and hepatitis C virus secondary to i.v. drug abuse and effects on prenatal brain development (1). Progress in the understanding of the causes of...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Betz C,Mihalic D,Pinto ME,Raffa RB

更新日期：2000-02-01 00:00:00

abstract：:The in vitro dissolution rates of 5 and 10 mg nifedipine capsules from eight suppliers were measured in simulated gastric fluid using the rotating paddle apparatus. A total of fourteen products were tested and the performance was found to be satisfactory for all products (> 80% dissolution in 20 min). ...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Mehta AC,Hart-Davies S,Kay EA

更新日期：1995-08-01 00:00:00

abstract：:A number of drugs have been reported to cause neuromuscular blockade and/or to increase weakness in myasthenia gravis. We report on two patients, treated with felodipine and nifedipine for arterial hypertension, who presented with an exacerbation of their myasthenia gravis and a myasthenic syndrome or exacerbation of ...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Pina Latorre MA,Cobeta JC,Rodilla F,Navarro N,Zabala S

更新日期：1998-10-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:The complexity and diversity of irritable bowel syndrome's (IBS) presentation make treatment difficult. Although there are reviews and guidelines for treating IBS, they focus on the efficacy of medications for IBS symptoms using high-priority endpoints, leaving those of lower priority largel...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Trinkley KE,Nahata MC

更新日期：2011-06-01 00:00:00

abstract：BACKGROUND:Upregulation of oligopeptide transport activity by dietary protein, certain dipeptides and amino acids has been reported in the rat intestine and a human intestinal cell line. OBJECTIVE:In this study, the pharmacokinetics of cefdinir were investigated after L-phenylalanine supplementation and a high-protein...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Fujita T,Nakamura K,Yamazaki A,Ozaki M,Sahashi K,Shichijo K,Nomura K,Maeda M,Nakamura T,Fujita T,Yokota S,Kuroyama S,Kumagai Y,Majima M,Ohtani Y

更新日期：2007-06-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Aloe vera (Aloe vera (L.) Burm.f., Xanthorrhoeaceae family) has long been used in folk or traditional medicine for diabetes. Several studies have been conducted on the effect of Aloe vera on glycaemic control, but the results appear inconsistent. We undertook a systematic review and meta-ana...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Suksomboon N,Poolsup N,Punthanitisarn S

更新日期：2016-04-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:There are no clinical reports that have compared topiroxostat, a selective xanthine oxidase inhibitor, with allopurinol in serum urate-lowering efficacy. The aim of this study was to compare the efficacy and safety of topiroxostat and allopurinol in Japanese hyperuricemic patients with or wi...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Hosoya T,Ogawa Y,Hashimoto H,Ohashi T,Sakamoto R

更新日期：2016-06-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Terlipressin is widely used to treat variceal bleeding and hepatorenal syndrome. We report one case of stubborn hyponatraemia induced by long-term (up to 21 days) therapy with terlipressin and review the side effects of this agent. CASE SUMMARY:A 41-year-old man with variceal rebleeding exp...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Huang Y,Wang M,Wang J

更新日期：2015-12-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Colchicine is an anti-inflammatory agent used primarily in treatment of gout and familial Mediterranean fever. Toxicity is uncommon, and depends on dose, hepatic or renal impairment, co-administration with P-glycoprotein or CYP3A4 inhibitors and route of administration. In patients taking p-...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Abodunde OA,LevakaVeera RR,Desai R,Nweke N,Berrou M

更新日期：2013-06-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Antituberculosis drug-induced liver injury (ATLI) is a serious adverse drug reaction, and its pathogenic mechanism is still largely unknown. Rifampin (RIF) has been reported to cause haemolysis due to the production of drug-dependent antibodies, and haemolysis results in an increased level o...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Tao B,Yang M,Chen H,Pan H,Liu W,Yi H,Tang S

更新日期：2020-08-01 00:00:00

abstract：:An imbalance of oxidative-antioxidant defence mechanism has been proposed in systemic lupus erythematosus patients. Co-administration of N-acetylcysteine (NAC) which has a strong antioxidant activity may produce a satisfactory therapeutic outcome when added to standard therapy. We report a case of a 46-year-old lupus ...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Tewthanom K,Janwitayanujit S,Totemchockcyakarn K,Panomvana Na Ayudhya D

更新日期：2010-08-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:CYP2C19*17 allele increases the metabolic activity of CYP2C19 resulting in decreased therapeutic levels of CYP2C19 substrates. There exist inter-ethnic differences in the distribution of this allele. The present study was aimed at establishing the allele and genotype frequencies of CYP2C19*1...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Anichavezhi D,Chakradhara Rao US,Shewade DG,Krishnamoorthy R,Adithan C

更新日期：2012-06-01 00:00:00

abstract：OBJECTIVE:To investigate the contribution of patient and doctor characteristics in explaining observed variations in prescribing costs between individual doctors. METHOD:Secondary analysis of data collected from general practitioners, Family Health Services Authorities, 1991 Census data set and the Prescription Pricin...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Gill PS,Roalfe A

更新日期：2001-12-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Carbamazepine is a potent inducer of cytochrome P450 3A and P-glycoprotein. However, there are no reports of the effects of carbamazepine on more than one co-administered drug. CASE SUMMARY:A 53-year-old female patient with schizophrenia and hypertension was on paliperidone 12 mg/day and am...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Akamine Y,Uehara H,Miura M,Yasui-Furukori N,Uno T

更新日期：2015-08-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Trimethylaminuria is a metabolic disorder characterized by excessive excretion of trimethylamine in body fluids following FMO3 gene mutations. Secondary forms of the disease may be due to consumption of trimethylamine precursor-rich foods or metabolism of some xenobiotics. CASE SUMMARY:A HI...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Scimone C,Alibrandi S,Donato L,Giofrè SV,Rao G,Sidoti A,D'Angelo R

更新日期：2020-11-28 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Adverse drug events (ADE), common and underestimated in ICU patients, have direct consequences on length of stay, mortality and hospital costs. Critically ill patients with HIV/AIDS are at a high risk of ADE because of their need for multiple drug therapies. ADE can be prevented, especially ...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Ramos GV,Guaraldo L,Japiassú AM,Bozza FA

更新日期：2015-02-01 00:00:00

abstract：:A stability-indicating reversed phase high-performance liquid chromatographic assay for prazosin was developed to investigate the feasibility of a transdermal dosage form. The assay enabled detection of drug concentrations down to 0.05 microgram/ml and the quantification of the drug in both permeation fluids and in ex...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Tenjarla SN,Tseggai A

更新日期：1992-02-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:This study aimed to compare the ability of statin monotherapy (ST group), omega-3 fatty acid monotherapy (OM_A group) and combination therapy with omega-3 fatty acids and a statin (OM_S group), to reduce triglyceride (TG) levels in patients with hypertriglyceridaemia. METHODS:In this retros...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Kim HS,Kim H,Jeong YJ,Yang SJ,Baik SJ,Lee H,Lee SH,Cho JH,Choi IY,Yim HW,Yoon KH

更新日期：2016-10-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Teneligliptin is a DPP-4 inhibitor used for the treatment of type 2 diabetes mellitus, commonly prescribed in combination with glimepiride. Teneligliptin is metabolized by CYP3A4, and glimepiride might be partly metabolized by CYP3A4. The aim of the study was to investigate the possible effe...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Park JW,Kim KA,Choi YJ,Yoon SH,Park JY

更新日期：2019-10-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Clinical use of fluconazole against fungal infections in renal transplant patients is complicated by the potentially marked and unpredictable drug-drug interactions (DDIs). We report a case of tacrolimus-fluconazole DDI in a stable renal transplant recipient and describe the mechanism, magni...

journal_title：Journal of clinical pharmacy and therapeutics

authors： He J,Yu Y,Yin C,Liu H,Zou H,Ma J,Yang W,Liu Y,Zhong L,Chen X

更新日期：2020-04-01 00:00:00

abstract：OBJECTIVE:Studies on antiepileptic drug utilization are important for the optimization of drug therapy and drug control. The present study was to evaluate the drug utilization pattern of standard antiepileptic drugs and traditional Chinese medicines (TCMs) in the treatment of different types of epilepsy in a general ho...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Chen LC,Chen YF,Yang LL,Chou MH,Lin MF

更新日期：2000-04-01 00:00:00